Quantitative ctDNA Detection in Hepatoblastoma: Implications for Precision Medicine.

Authors: Kahana-Edwin, Smadar¹ (AUTHOR) smadar.kahanaedwin@health.nsw.gov.au, Torpy, James² (AUTHOR), Cain, Lucy E.³ (AUTHOR), Mullins, Anna³ (AUTHOR), McCowage, Geoffrey³ (AUTHOR), Woodfield, Sarah E.⁴ (AUTHOR), Vasudevan, Sanjeev A.⁴ (AUTHOR), Shea, Dan P. T.² (AUTHOR), Minoche, Andre E.² (AUTHOR), Espinoza, Andres F.⁴ (AUTHOR), Kummerfeld, Sarah^2,5 (AUTHOR), Goldstein, Leonard D.^2,5 (AUTHOR), Karpelowsky, Jonathan^1,6,7 (AUTHOR)

Source: Cancers. Jan2024, Vol. 16 Issue 1, p12. 15p.

Subject Terms: *ALPHA fetoproteins, *DNA, *SCIENTIFIC observation, *HEPATOBLASTOMA, *INDIVIDUALIZED medicine, *QUANTITATIVE research, *CANCER patients, *COMPARATIVE studies, *RESEARCH funding, *TUMOR markers, *COMBINED modality therapy, *SENSITIVITY & specificity (Statistics), *DECISION making in clinical medicine, *LONGITUDINAL method, BODY fluid examination

Roadmap to Liquid Biopsy Biobanking from Pediatric Cancers–Challenges and Opportunities

Authors: Kahana-Edwin, Smadar, Cain, Lucy E., Karpelowsky, Jonathan

Source: Biopreservation and biobanking. 19(2):124-129

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100150486184.0x000001&indx=1&recIds=ETOCvdc_100150486184.0x000001

TNFR2+ TILs are significantly associated with improved survival in triple-negative breast cancer patients

Authors: Dadiani, Maya, Necula, Daniela, Kahana-Edwin, Smadar, Oren, Nino, Baram, Tamir, Marin, Irina, Morzaev-Sulzbach, Dana, Pavlovski, Anya, Balint-Lahat, Nora, Anafi, Liat, Wiemann, Stefan, Korner, Cindy, Gal-Yam, Einav Nili, Avivi, Camila, Kaufman, Bella, Barshack, Iris, Ben-Baruch, Adit

Source: Cancer immunology, immunotherapy. 69(7):1315-1326

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167889523.0x000001&indx=1&recIds=ETOCvdc_100167889523.0x000001

From Pediatric to Adult Brain Cancer: Exploring Histone H3 Mutations in Australian Brain Cancer Patients.

Authors: Grebstad Tune, Benedicte, Sareen, Heena, Powter, Branka, Kahana-Edwin, Smadar, Cooper, Adam, Koh, Eng-Siew, Lee, Cheok S., Po, Joseph W., McCowage, Geoff, Dexter, Mark, Cain, Lucy, O'Neill, Geraldine, Prior, Victoria, Karpelowsky, Jonathan, Tsoli, Maria, Baumbusch, Lars O., Ziegler, David, Roberts, Tara L., DeSouza, Paul, Becker, Therese M.

Source: Biomedicines; Nov2023, Vol. 11 Issue 11, p2907, 12p

Subject Terms: BRAIN cancer, CANCER patients, CELL-free DNA, CHILD patients, GENETIC variation, BRAIN tumors

Geographic Terms: SYDNEY (N.S.W.)

Exploration of CTNNB1 ctDNA as a putative biomarker for hepatoblastoma

Authors: Kahana‐Edwin, Smadar, McCowage, Geoffrey, Cain, Lucy, Saletta, Federica, Yuksel, Aysen, Graf, Nicole, Karpelowsky, Jonathan

Source: Pediatric blood & cancer. 67(11)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107611689.0x000001&indx=1&recIds=ETOCvdc_100107611689.0x000001

ESR1 mutations are frequent in newly diagnosed metastatic and loco-regional recurrence of endocrine-treated breast cancer and carry worse prognosis

Authors: Zundelevich, Adi, Dadiani, Maya, Kahana-Edwin, Smadar, Itay, Amit, Sella, Tal, Gadot, Moran, Cesarkas, Karen, Farage-Barhom, Sarit, Saar, Efrat Glick, Eyal, Eran, Kol, Nitzan, Pavlovski, Anya, Balint-Lahat, Nora, Dick-Necula, Daniela, Barshack, Iris, Kaufman, Bella, Gal-Yam, Einav Nili

Source: Breast cancer research. 22(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164301971.0x000001&indx=1&recIds=ETOCvdc_100164301971.0x000001

Correction to: ESR1 mutations are frequent in newly diagnosed metastatic and loco-regional recurrence of endocrine-treated breast cancer and carry worse prognosis

Authors: Zundelevich, Adi, Dadiani, Maya, Kahana-Edwin, Smadar, Itay, Amit, Sella, Tal, Gadot, Moran, Cesarkas, Karen, Farage-Barhom, Sarit, Saar, Efrat Glick, Eyal, Eran, Kol, Nitzan, Pavlovski, Anya, Balint-Lahat, Nora, Dick-Necula, Daniela, Barshack, Iris, Kaufman, Bella, Gal-Yam, Einav Nili

Source: Breast cancer research. 22(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164288316.0x000001&indx=1&recIds=ETOCvdc_100164288316.0x000001

Divergence of mutational signatures in association with breast cancer subtype.

Authors: Perry, Gili, Dadiani, Maya, Kahana‐Edwin, Smadar, Pavlovski, Anya, Markus, Barak, Hornung, Gil, Balint‐Lahat, Nora, Yosepovich, Ady, Hout‐Siloni, Goni, Jacob‐Hirsch, Jasmine, Sklair‐Levy, Miri, Friedman, Eitan, Barshack, Iris, Kaufman, Bella, Gal‐Yam, Einav Nili, Paluch‐Shimon, Shani

Source: Molecular Carcinogenesis; Nov2022, Vol. 61 Issue 11, p1056-1070, 15p

Multiple MAPK Cascades Regulate the Transcription of IME1, the Master Transcriptional Activator of Meiosis in Saccharomyces cerevisiae.

Authors: Kahana-Edwin, Smadar¹, Stark, Michal¹, Kassir, Yona¹ ykassir@tx.technion.ac.il

Source: PLoS ONE. Nov2013, Vol. 8 Issue 11, p1-12. 12p.

Subject Terms: *MITOGEN-activated protein kinases, *GENETIC transcription, *MEIOSIS, *SACCHAROMYCES cerevisiae, *YEAST, *GAMETOGENESIS, *CELLULAR signal transduction, *REPRODUCTION

Neuroblastoma Molecular Risk-Stratification of DNA Copy Number and ALK Genotyping via Cell-Free Circulating Tumor DNA Profiling.

Authors: Kahana-Edwin, Smadar¹ (AUTHOR) FSaletta@ccia.org.au, Cain, Lucy E.² (AUTHOR) lucy.cain@health.nsw.gov.au, McCowage, Geoffrey² (AUTHOR) geoff.mccowage@health.nsw.gov.au, Darmanian, Artur³ (AUTHOR) artur.darmanian@health.nsw.gov.au, Wright, Dale^3,4 (AUTHOR) dale.wright@health.nsw.gov.au, Mullins, Anna² (AUTHOR) Anna.Mullins@health.nsw.gov.au, Saletta, Federica¹ (AUTHOR) jonathan.karpelowsky@sydney.edu.au, Karpelowsky, Jonathan^1,4,5 (AUTHOR)

Source: Cancers. Jul2021, Vol. 13 Issue 13, p3365-3365. 1p.

Subject Terms: *BIOMARKERS, *NEUROBLASTOMA, *MOLECULAR diagnosis, *SINGLE nucleotide polymorphisms, *RISK assessment, *GENE expression profiling, *EXTRACELLULAR space, *NUCLEIC acids, *DISEASE risk factors

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Multiple MAPK Cascades Regulate the Transcription of IME1, the Master Transcriptional Activator of Meiosis in Saccharomyces cerevisiae.

Authors: Kahana-Edwin, Smadar, Stark, Michal, Kassir, Yona

Source: PLoS ONE; Nov2013, Vol. 8 Issue 11, p1-12, 12p

Subject Terms: MITOGEN-activated protein kinases, GENETIC transcription, MEIOSIS, SACCHAROMYCES cerevisiae, YEAST, GAMETOGENESIS, CELLULAR signal transduction, REPRODUCTION

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