Persistent Diarrhea in Patients With Crohn’s Disease After Mucosal Healing Is Associated With Lower Diversity of the Intestinal Microbiome and Increased Dysbiosis

Authors: Boland, Karen, Bedrani, Larbi, Turpin, Williams, Kabakchiev, Boyko, Stempak, Joanne, Borowski, Krzysztof, Nguyen, Geoffrey, Steinhart, A. Hillary, Smith, Michelle I., Croitoru, Kenneth, Silverberg, Mark S.

Source: In Clinical Gastroenterology and Hepatology February 2021 19(2):296-304

Individualized Medication Management in Ontario Long-Term Care Clinical Impact on Management of Depression, Pain, and Dementia

Authors: Dorfman, Ruslan, London, Zana, Metias, Mark, Kabakchiev, Boyko, Mukerjee, Gouri, Moser, Andrea

Source: In Journal of the American Medical Directors Association June 2020 21(6):823-829

PARC report: health outcomes and value of personalized medicine interventions: impact on patient care

Authors: Mitropoulou, Christina, Litinski, Veronika, Kabakchiev, Boyko, Rogers, Sara, P Patrinos, George

Source: Pharmacogenomics. 21(11):797-807

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186604047.0x000001&indx=1&recIds=ETOCvdc_100186604047.0x000001

Histological Markers of Clinical Relapse in Endoscopically Quiescent Ulcerative Colitis

Authors: Kevans, David, Kirsch, Richard, Dargavel, Callum, Kabakchiev, Boyko, Riddell, Robert, Silverberg, Mark S

Source: Inflammatory bowel diseases. 26(11):1722-1729

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108991258.0x000001&indx=1&recIds=ETOCvdc_100108991258.0x000001

Differential miRNA Expression in Ileal and Colonic Tissues Reveals an Altered Immunoregulatory Molecular Profile in Individuals With Crohn's Disease versus Healthy Subjects

Authors: Mohammadi, Aylia, Kelly, Orlaith B, Smith, Michelle I, Kabakchiev, Boyko, Silverberg, Mark S

Source: Journal of Crohn's and colitis. 13(11):1459-1469

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100100508712.0x000001&indx=1&recIds=ETOCvdc_100100508712.0x000001

User considerations in assessing pharmacogenomic tests and their clinical support tools

Authors: Mukerjee, Gouri, Huston, Andrea, Kabakchiev, Boyko, Piquette-Miller, Micheline, Schaik, Ron, Dorfman, Ruslan

Source: Npj genomic medicine. 3:1-9

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183624472.0x000001&indx=1&recIds=ETOCvdc_100183624472.0x000001

Development of the Harvey-Bradshaw Index-pro (HBI-PRO) Score to Assess Endoscopic Disease Activity in Crohn's Disease

Authors: Zittan, Eran, Kabakchiev, Boyko, Kelly, Orlaith B., Milgrom, Raquel, Nguyen, Geoffrey C., Croitoru, Kenneth, Steinhart, A. Hillary, Silverberg, Mark S.

Source: Journal of Crohn's and colitis. 11(5):543-548

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN620510930&indx=1&recIds=ETOCRN620510930

Microbiome Heterogeneity Characterizing Intestinal Tissue and Inflammatory Bowel Disease Phenotype

Authors: Tyler, Andrea D., Kirsch, Richard, Milgrom, Raquel, Stempak, Joanne M., Kabakchiev, Boyko, Silverberg, Mark S.

Source: Inflammatory bowel diseases. 22(4):807-816

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100037056875.0x000001&indx=1&recIds=ETOCvdc_100037056875.0x000001

Expression Quantitative Trait Loci Analysis Identifies Associations Between Genotype and Gene Expression in Human Intestine

Authors: Kabakchiev, Boyko, Silverberg, Mark S.

Source: In Gastroenterology June 2013 144(7):1488-1496

Downregulation of Expression of Xenobiotic Efflux Genes is Associated with Pelvic Pouch Inflammation in Ulcerative Colitis

Authors: Kabakchiev, Boyko, Tyler, Andrea, Stempak, Joanne M., Milgrom, Raquel, Silverberg, Mark S.

Source: Inflammatory bowel diseases. 20(7):1157-1164

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100030365668.0x000001&indx=1&recIds=ETOCvdc_100030365668.0x000001

257 – Higher Abundance of Bile Acid-Metabolizing Microbiota is Associated with Type of Disease, Biopsy Location and Mucosal Inflammation in Inflammatory Bowel Disease Patients

Authors: Hernandez-Rocha, Cristian, Kabakchiev, Boyko, Borowski, Krzysztof, Turpin, Williams, Boland, Karen, Milgrom, Raquel, Stempak, Joanne M., Smith, Michelle I., Silverberg, Mark S.

Source: Gastroenterology. 156(6):S-49-S-49

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100080955587.0x000001&indx=1&recIds=ETOCvdc_100080955587.0x000001

Tu1831 – Use of Drug-Tolerant Assays in Inflammatory Bowel Disease; What Does It Tell Us?

Authors: Walshe, Margaret, Borowski, Krzysztof, Kabakchiev, Boyko, Milgrom, Raquel, Stempak, Joanne M., Steinhart, A. Hillary, Croitoru, Kenneth, Silverberg, Mark S.

Source: Gastroenterology. 156(6):S-1142-S-1142

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100080947660.0x000001&indx=1&recIds=ETOCvdc_100080947660.0x000001

475 - Clinical Predictors of Recurrence after End Ileostomy and Colectomy for Crohn's Disease

Authors: Boland, Karen, Li, Rachelle, Soriano, Joelle, Stempak, Joanne M., Kabakchiev, Boyko, O'Connor, Brenda, Brar, Mantaj S., Kennedy, Erin, Cohen, Zane, Silverberg, Mark S.

Source: Gastroenterology. 154(6):S-112-S-112

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100085562961.0x000001&indx=1&recIds=ETOCvdc_100085562961.0x000001

Su1008 – Mir874-3P is Inversely Correlated with Its Target Atg16L1 in T-Cells of Inflammatory Bowel Disease Patients

Authors: Filice, Melissa, Kabakchiev, Boyko, Parsons, Michael, Mohammadi, Aylia, Smith, Michelle I., Silverberg, Mark S.

Source: Gastroenterology. 156(6):S-483-S-484

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100080966012.0x000001&indx=1&recIds=ETOCvdc_100080966012.0x000001

Microbial Composition in IBD May Influence Clinical Symptoms Independent of Endoscopic Activity

Authors: Boland, Karen, Turpin, Williams, Mohammadi, Aylia, Borowski, Krzysztof, Kabakchiev, Boyko, Stempak, Joanne M., Smith, Michelle I., Nguyen, Geoffrey C., Hillary Steinhart, A., Croitoru, Kenneth, Silverberg, Mark S.

Source: Gastroenterology. 152(5):S193-S194

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100054023668.0x000001&indx=1&recIds=ETOCvdc_100054023668.0x000001

Ulcerative Colitis Patients on Vedolizumab Lacking Response at Induction Phase Continue to Improve Over the First 6 Months of Treatment

Authors: Zezos, Petros, Kabakchiev, Boyko, Weizman, Adam, Nguyen, Geoffrey C., Narula, Neeraj, Croitoru, Kenneth, Hillary Steinhart, A., Silverberg, Mark S.

Source: Gastroenterology. 152(5):S400-S401

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100054002256.0x000001&indx=1&recIds=ETOCvdc_100054002256.0x000001

Identification of Target Golimumab Levels in Maintenance Therapy of Crohn's Disease and Ulcerative Colitis Associated With Mucosal Healing.

Authors: Boland, Karen, Greener, Tomer, Kabakchiev, Boyko, Stempak, Joanne, Tessolini, Jenna, Li, Rachelle, Soriano, Joelle, Croitoru, Kenneth, Nguyen, Geoffrey, Steinhart, A Hillary, Weizman, Adam V, Silverberg, Mark S

Source: Inflammatory Bowel Diseases; May2020, Vol. 26 Issue 5, p766-773, 8p

Ulcerative Colitis Patients Continue to Improve Over the First Six Months of Vedolizumab Treatment: 12-Month Clinical and Mucosal Healing Effectiveness.

Authors: Zezos, Petros, Kabakchiev, Boyko, Weizman, Adam V, Nguyen, Geoffrey C, Narula, Neeraj, Croitoru, Kenneth, Steinhart, A Hillary, Silverberg, Mark S

Source: Journal of the Canadian Association of Gastroenterology; Apr2020, Vol. 3 Issue 2, p74-82, 9p

Gene Expression Changes Associated with Resistance to Intravenous Corticosteroid Therapy in Children with Severe Ulcerative Colitis.

Authors: Kabakchiev, Boyko^1,2 kabakchiev@lunenfeld.ca, Turner, Dan³, Hyams, Jeffrey⁴, Mack, David⁵, Leleiko, Neal⁶, Crandall, Wallace⁷, Markowitz, James⁸, Otley, Anthony R.⁹, Wei Xu², Pingzhao Hu¹⁰, Griffiths, Anne M.¹⁰, Silverberg, Mark S.^1,2

Source: PLoS ONE. 2010, Vol. 5 Issue 9, p1-8. 8p.

Subject Terms: *GENE expression, *GENES, *COLITIS, *ULCERATIVE colitis in children, *PEDIATRIC gastroenterology, *RNA, *INFLAMMATION, *CORTICOSTEROIDS, *ADRENAL cortex, *STEROID hormones

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