Induced pluripotent stem-cell-derived CD19-directed chimeric antigen receptor natural killer cells in B-cell lymphoma: a phase 1, first-in-human trial.

Authors: Ghobadi, Armin¹ (AUTHOR), Bachanova, Veronika² (AUTHOR), Patel, Krish³ (AUTHOR), Park, Jae H⁴ (AUTHOR), Flinn, Ian⁵ (AUTHOR), Riedell, Peter A⁶ (AUTHOR), Bachier, Carlos⁷ (AUTHOR), Diefenbach, Catherine S⁸ (AUTHOR), Wong, Carol⁹ (AUTHOR), Bickers, Cara⁹ (AUTHOR), Wong, Lilly⁹ (AUTHOR), Patel, Deepa⁹ (AUTHOR), Goodridge, Jode⁹ (AUTHOR), Denholt, Matthew⁹ (AUTHOR), Valamehr, Bahram⁹ (AUTHOR), Elstrom, Rebecca L⁹ (AUTHOR), Strati, Paolo¹⁰ (AUTHOR)

Source: Lancet. Jan2025, Vol. 405 Issue 10473, p127-136. 10p.

Subject Terms: Killer cells, Killer cell receptors, Cytokine release syndrome, Chimeric antigen receptors, FC receptors

Non‐invasive molecular biomarkers for monitoring solid organ transplantation: A comprehensive overview.

Authors: Fernando, Jeffy J¹ (AUTHOR), Biswas, Raja¹ (AUTHOR), Biswas, Lalitha¹ (AUTHOR) lalithabiswas@aims.amrita.edu

Source: International Journal of Immunogenetics. Apr2024, Vol. 51 Issue 2, p47-62. 16p.

Subject Terms: *KILLER cell receptors, *TRANSPLANTATION of organs, tissues, etc., *BIOMARKERS, *GRAFT rejection, *GENETIC regulation, *CELL-free DNA, *VESICLES (Cytology)

Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes.

Authors: Mora-Bitria, Laura^1,2, Debebe, Bisrat J.¹, Miners, Kelly L.³, Ladell, Kristin³, Kaur, Charandeep¹, Traherne, James A.⁴, Jiang, Wei⁴, Price, David A.^3,5, Hadcocks, Linda⁶, McQuibban, Nicholas A. R.^1,7, Trowsdale, John⁴, Wong, F Susan³, Pontikos, Nikolas⁸, Niederalt, Christoph², Asquith, Becca¹, b.asquith@imperial.ac.uk

Source: PLoS Genetics; 12/26/2024, Vol. 20 Issue 12, p1-29, 29p

Molecular relapse monitoring reveals the domination of impaired NK cell education over impaired inhibition in missing KIR‐ligand recognition in patients after unrelated hematopoietic stem cell transplantation for malignant diseases.

Authors: Nowak, Jacek¹ (AUTHOR) jnowak@ihit.waw.pl, Witkowska, Agnieszka¹ (AUTHOR), Rogatko‐Koroś, Marta¹ (AUTHOR), Malinowska, Agnieszka¹ (AUTHOR), Graczyk‐Pol, Elżbieta¹ (AUTHOR), Nestorowicz‐Kałużna, Klaudia² (AUTHOR), Flaga, Anna¹ (AUTHOR), Szlendak, Urszula¹ (AUTHOR), Wnorowska, Anna¹ (AUTHOR), Gawron, Agnieszka¹ (AUTHOR)

Source: HLA: Immune Response Genetics. Feb2024, Vol. 103 Issue 2, p1-15. 15p.

Subject Terms: *HEMATOPOIETIC stem cell transplantation, *KILLER cell receptors, *KILLER cells, *CANCER cells, *MOLECULAR recognition, *CHRONIC myeloid leukemia, *HEMATOLOGIC malignancies, *HEMATOPOIETIC stem cells

Complete HLA genotyping of type 1 diabetes patients and controls from Mali reveals both expected and novel disease associations.

Authors: Noble, Janelle A.^1,2 (AUTHOR) jnoble58@berkeley.edu, Besançon, Stéphane³ (AUTHOR), Sidibé, Assa Traore⁴ (AUTHOR), Rozemuller, Erik H.⁵ (AUTHOR), Rijkers, Maaike⁵ (AUTHOR), Dadkhodaie, Fereshte⁵ (AUTHOR), de Bruin, Helma⁵ (AUTHOR), Kooij, Jannetje⁵ (AUTHOR), Martin, Harper R. N.¹ (AUTHOR), Ogle, Graham D.^6,7 (AUTHOR), Mack, Steven J.² (AUTHOR)

Source: HLA: Immune Response Genetics. Jan2024, Vol. 103 Issue 1, p1-16. 16p.

Subject Terms: *KILLER cell receptors, *TYPE 1 diabetes, *PEOPLE with diabetes, *LINKAGE disequilibrium, *HAPLOTYPES, *HISTOCOMPATIBILITY class I antigens

Geographic Terms: MALI

A retrospective analysis to evaluate if KIR B haplotype donors associate with a reduced risk of relapse in patients with haematological malignancies following haploidentical transplantation at the Blood and Bone Marrow Transplant Unit at Hammersmith Hospital ICHNHST

Authors: Byrnes, Christopher Paul^1,2 (AUTHOR) christopher.byrnes@nhs.net, Hastings, Andrew³ (AUTHOR), Lacej, Ira³ (AUTHOR), Palanicawandar, Renuka⁴ (AUTHOR), Olavarria, Eduardo⁴ (AUTHOR), Anand, Arthi¹ (AUTHOR)

Source: HLA: Immune Response Genetics. Jan2024, Vol. 103 Issue 1, p1-14. 14p.

Subject Terms: *KILLER cell receptors, *BONE marrow, *BONE marrow transplantation, *GRAFT versus host disease, *KILLER cells, *DISEASE relapse, *HAPLOTYPES

Exceptional diversity of KIR and HLA class I in Egypt.

Authors: Montero‐Martin, Gonzalo¹ (AUTHOR), Kichula, Katherine M.² (AUTHOR), Misra, Maneesh K.^3,4 (AUTHOR), de Brito Vargas, Luciana² (AUTHOR), Marin, Wesley M.³ (AUTHOR), Hollenbach, Jill A.³ (AUTHOR), Fernández‐Viña, Marcelo A.¹ (AUTHOR), Elfishawi, Sally⁵ (AUTHOR), Norman, Paul J.^2,6 (AUTHOR) paul.norman@ucdenver.edu

Source: HLA: Immune Response Genetics. Jan2024, Vol. 103 Issue 1, p1-13. 13p.

Subject Terms: *KILLER cell receptors, *KILLER cells, *IMMUNOGLOBULIN receptors, *NATURAL selection, *HAPLOTYPES, *HISTOCOMPATIBILITY class I antigens, *REPRODUCTIVE health

Geographic Terms: EGYPT, CAIRO (Egypt)

Therapeutic potential of anti-ErbB3 chimeric antigen receptor natural killer cells against breast cancer.

Authors: Lee, Juheon¹ (AUTHOR), Song, Jinhoo¹ (AUTHOR), Yoo, Wonbeak² (AUTHOR), Choi, Hyunji² (AUTHOR), Jung, Dana¹ (AUTHOR), Choi, Eunjeong¹ (AUTHOR), Jo, Seo-Gyeong¹ (AUTHOR), Gong, Eun-Yeung³ (AUTHOR), Jeoung, Young-Hee³ (AUTHOR), Park, You-Soo⁴ (AUTHOR), Son, Woo-Chang⁴ (AUTHOR), Lee, Hosuk⁵ (AUTHOR), Lee, Hayoung⁵ (AUTHOR), Kim, Jeom Ji⁵ (AUTHOR), Kim, TaeEun⁵ (AUTHOR), Lee, Sooyun⁶ (AUTHOR), Park, Jang-June⁵ (AUTHOR) jangjune.park@isu.co.kr, Kim, Tae-Don^6,7 (AUTHOR) tdkim@kribb.re.kr, Kim, Seok-Ho^1,3 (AUTHOR) cvaccine@dau.ac.kr

Source: Cancer Immunology, Immunotherapy. Feb2025, Vol. 74 Issue 2, p1-15. 15p.

Subject Terms: *KILLER cells, *KILLER cell receptors, *CHIMERIC antigen receptors, *MEDICAL sciences, *TUMOR-infiltrating immune cells

Recognition of Self and Viral Ligands by NK Cell Receptors.

Authors: Mariuzza, Roy A.^1,2 (AUTHOR) rmariuzz@umd.edu, Singh, Pragya^1,3 (AUTHOR), Karade, Sharanbasappa S.^1,2 (AUTHOR), Shahid, Salman^1,2 (AUTHOR), Sharma, Vijay Kumar^1,2 (AUTHOR)

Source: Immunological Reviews. Jan2025, Vol. 329 Issue 1, p1-16. 16p.

Subject Terms: *KILLER cell receptors, *IMMUNE response, *TUMOR antigens, *RECOGNITION (Psychology), *VIRAL antigens, *ANTIBODY-dependent cell cytotoxicity, *KILLER cells, *LIGANDS (Biochemistry)

Killer Cell Immunoglobulin-Like Receptor Genes Distribution in Southeastern Anatolia Population in Turkey.

Authors: Mihcioglu, D.¹ (AUTHOR) denizmihcioglu@hotmail.com, Gerceker, F. Ozbas² (AUTHOR), Tufioglu, E.² (AUTHOR), Yilmaz, T.² (AUTHOR)

Source: Biology Bulletin. 2023 Suppl 3, Vol. 50, pS317-S324. 8p.

Subject Terms: *KILLER cell receptors, *KILLER cells, *IMMUNOREGULATION, *TURKS, *GENES, *GENE families, *PSEUDOGENES

Geographic Terms: TURKEY

Porcine UL-16 Binding Protein 1 Is Not a Functional Ligand for the Human Natural Killer Cell Activating Receptor NKG2D.

Authors: Lopez, Kevin J.¹ (AUTHOR) kevlopez@iu.edu, Spence, John Paul² (AUTHOR) jspence@iupui.edu, Li, Wei³ (AUTHOR) wl1@iupui.edu, Zhang, Wenjun¹ (AUTHOR) wenzhang@iu.edu, Wei, Barry¹ (AUTHOR) barrwei@iu.edu, Cross-Najafi, Arthur A.¹ (AUTHOR) acrossna@iupui.edu, Butler, James R.¹ (AUTHOR) jrbutler@iupui.edu, Cooper, David K. C.⁴ (AUTHOR) dkcooper@mgh.harvard.edu, Ekser, Burcin¹ (AUTHOR) bekser@iupui.edu, Li, Ping¹ (AUTHOR) bekser@iupui.edu

Source: Cells (2073-4409). Nov2023, Vol. 12 Issue 22, p2587. 11p.

Subject Terms: *KILLER cell receptors, *KILLER cells, *CARRIER proteins, *GENOME editing, *IMMUNOLOGICAL tolerance, *GENE knockout

Possible impact of HLA class I and class II on malignancies driven by a single germ‐line BRCA1 mutation.

Authors: Ivanova, Milena¹ (AUTHOR) mivanova@intech.bg, Ormandjieva, Anastasia¹ (AUTHOR), Dodova, Rumyana² (AUTHOR), Kaneva, Radka² (AUTHOR), Shivarov, Velizar³ (AUTHOR) vshivarov@abv.bg

Source: International Journal of Immunogenetics. Oct2023, Vol. 50 Issue 5, p243-248. 6p.

Subject Terms: *BRCA genes, *KILLER cell receptors, *ALLELES, *HAPLOTYPES, *LEUKOCYTES

Killer Cell Immunoglobulin-like Receptor Genotypes and Reproductive Outcomes in a Group of Infertile Women: A Romanian Study.

Authors: Surcel, Mihai¹ (AUTHOR) surcel.mihai75@gmail.com, Neamtiu, Iulia Adina^2,3 (AUTHOR) iulia.neamtiu@alsglobal.com, Muresan, Daniel¹ (AUTHOR) daniel.muresan@umfcluj.ro, Goidescu, Iulian¹ (AUTHOR) iuliangoidescu@gmail.com, Staicu, Adelina¹ (AUTHOR) adelina.staicu@umfcluj.ro, Marta, Monica Mihaela⁴ (AUTHOR) mmarta@umfcluj.ro, Nemeti, Georgiana¹ (AUTHOR) georgiana_nemeti@yahoo.com, Harsa, Radu⁵ (AUTHOR) raduharsa@gmail.com, Doroftei, Bogdan⁶ (AUTHOR) bogdandoroftei@gmail.com, Capilna, Mihai Emil⁷ (AUTHOR) mcapilna@gmail.com, Caracostea, Gabriela¹ (AUTHOR) caracostea1@yahoo.com

Source: Diagnostics (2075-4418). Oct2023, Vol. 13 Issue 19, p3048. 12p.

Subject Terms: *KILLER cell receptors, *REPRODUCTIVE health, *GENOTYPES, *KILLER cells, *HYSTEROSCOPY, *FERTILIZATION in vitro, *REPRODUCTIVE history

Geographic Terms: ROMANIA

CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan.

Authors: Heilig, Linda¹, Natasha, Fariha², Trinks, Nora², Aimanianda, Vishukumar³, Wong, Sarah Sze Wah³, Fontaine, Thierry⁴, Terpitz, Ulrich², Strobel, Lea¹, Le Mauff, François^5,6, Sheppard, Donald C.^5,6,7,8, Schäuble, Sascha⁹, Kurzai, Oliver^10,11, Hünniger, Kerstin¹⁰, Weiss, Esther¹, Vargas, Mario¹², Howell, P. Lynne^12,13, Panagiotou, Gianni^9,14,15, Wurster, Sebastian¹⁶, Einsele, Hermann¹, Loeffler, Juergen¹, Loeffler_J@ukw.de

Source: PLoS Pathogens; 6/18/2024, Vol. 20 Issue 6, p1-28, 28p

Genotype List String 1.1: Extending the Genotype List String grammar for describing HLA and Killer‐cell Immunoglobulin‐like Receptor genotypes.

Authors: Mack, Steven J.¹ (AUTHOR) steven.mack@ucsf.edu, Schefzyk, Daniel² (AUTHOR), Millius, Robert P.³ (AUTHOR), Maiers, Martin³ (AUTHOR), Hollenbach, Jill A.^4,5 (AUTHOR), Pollack, Jane³ (AUTHOR), Heuer, Michael L.³ (AUTHOR), Gragert, Loren⁶ (AUTHOR), Spellman, Stephen R.⁷ (AUTHOR), Guethlein, Lisbeth A.⁸ (AUTHOR), Schneider, Joel³ (AUTHOR), Bochtler, Werner⁹ (AUTHOR), Eberhard, Hans‐Peter⁹ (AUTHOR), Robinson, James^10,11 (AUTHOR), Marsh, Steven G. E.^10,11 (AUTHOR), Schmidt, Alexander H.² (AUTHOR), Hofmann, Jan A.² (AUTHOR), Sauter, Jürgen² (AUTHOR)

Source: HLA: Immune Response Genetics. Aug2023, Vol. 102 Issue 2, p206-212. 7p.

Subject Terms: *GENOTYPES, *KILLER cell receptors, *GRAMMAR, *CYTOTOXIC T cells, *DATA recorders & recording

Association of killer cell immunoglobulin-like receptors and their cognate HLA class I ligands with susceptibility to acute myeloid leukemia in Iranian patients.

Authors: Mirzazadeh, Sara¹ (AUTHOR), Bemani, Peyman² (AUTHOR), Halimi, Hossein¹ (AUTHOR), Sanaee, Mohammad Nabi³ (AUTHOR), Karami, Narges¹ (AUTHOR), Ramzi, Mani³ (AUTHOR), Farjadian, Shirin¹ (AUTHOR) shirinenator@gmail.com

Source: Scientific Reports. 7/15/2023, Vol. 13 Issue 1, p1-11. 11p.

Subject Terms: *KILLER cell receptors, *ACUTE myeloid leukemia, *HISTOCOMPATIBILITY class I antigens, *IRANIANS, *KILLER cells, *CYTOTOXIC T cells, *LIGANDS (Biochemistry)

A genome assembly and transcriptome atlas of the inbred Babraham pig to illuminate porcine immunogenetic variation.

Authors: Schwartz, John C.¹ (AUTHOR), Farrell, Colin P.^2,3 (AUTHOR), Freimanis, Graham¹ (AUTHOR), Sewell, Andrew K.⁴ (AUTHOR), Phillips, John D.² (AUTHOR), Hammond, John A.¹ (AUTHOR) john.hammond@pirbright.ac.uk

Source: Immunogenetics. Dec2024, Vol. 76 Issue 5/6, p361-380. 20p.

Subject Terms: *KILLER cell receptors, *B cell receptors, *T cell receptors, *GENE expression, *GENE families, *CENTROMERE

Anti‐PD‐L1 chimeric antigen receptor natural killer cell: Characterization and functional analysis.

Authors: Yazdanpanah‐Samani, Mahsa¹ (AUTHOR), Ramezani, Amin^1,2 (AUTHOR), Sheikhi, Abdolkarim³ (AUTHOR), Mostafavi‐Pour, Zohreh^4,5 (AUTHOR) zmostafavipour88@yahoo.co.uk, Erfani, Nasrollah^2,6 (AUTHOR) erfanin@sums.ac.ir

Source: APMIS. Dec2024, Vol. 132 Issue 12, p1115-1127. 13p.

Subject Terms: *SUPPRESSOR cells, *KILLER cell receptors, *IMMUNE checkpoint inhibitors, *CHIMERIC antigen receptors, *CELL receptors

Causal relationship of inflammatory cytokines and serum metabolites in cerebral small vessel disease: a two‐step Mendelian randomization study.

Authors: Li, Zidong¹ (AUTHOR), Miao, Lu² (AUTHOR), Zhang, Tianyi³ (AUTHOR), Thomas, Aline M.⁴ (AUTHOR), Li, Shen^1,5 (AUTHOR) lishen@mail.ccmu.edu.cn

Source: European Journal of Neurology. Dec2024, Vol. 31 Issue 12, p1-10. 10p.

Subject Terms: *CEREBRAL small vessel diseases, *KILLER cell receptors, *KILLER cells, *FIBROBLAST growth factors, *CEREBRAL amyloid angiopathy, *WHITE matter (Nerve tissue), *MENDELIAN randomization

An archaic HLA class I receptor allele diversifies natural killer cell-driven immunity in First Nations peoples of Oceania.

Authors: Loh, Liyen^1,2, Saunders, Philippa M.¹, Faoro, Camilla^1,3, Font-Porterias, Neus^1,4, Nemat-Gorgani, Neda⁵, Harrison, Genelle F.⁴, Sadeeq, Suraju⁴, Hensen, Luca¹, Wong, Shu Cheng¹, Widjaja, Jacqueline¹, Clemens, E. Bridie¹, Zhu, Shiying³, Kichula, Katherine M.⁴, Tao, Sudan^4,6, Zhu, Faming⁶, Montero-Martin, Gonzalo⁷, Fernandez-Vina, Marcelo⁷, Guethlein, Lisbeth A.⁵, Vivian, Julian P.³, Davies, Jane^8,9

Source: Cell; Nov2024, Vol. 187 Issue 24, p7008-70702, 63695p