Three-Step Enzymatic Remodeling of Chitin into Bioactive Chitooligomers

Authors: Mészáros, Zuzana, Kulik, Natalia, Petrásková, Lucie, Bojarová, Pavla, Texidó, Mònica, Planas, Antoni, Křen, Vladimír, Slámová, Kristýna

Source: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. 72(28):15613-15623

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632746055&indx=1&recIds=ETOCRN632746055

The variable structural flexibility of the Bacillus circulans β-galactosidase isoforms determines their unique functionalities

Authors: Hovorková, Michaela, Kaščáková, Barbora, Petrásková, Lucie, Havlíčková, Petra, Nováček, Jiří, Pinkas, Daniel, Gardian, Zdenko, Křen, Vladimír, Bojarová, Pavla, Smatanová, Ivana Kutá

Source: In Structure 7 November 2024 32(11):2023-2037

Diaminocyclopentane – l-Lysine Adducts: Potent and selective inhibitors of human O-GlcNAcase

Authors: Weber, Patrick, Bojarová, Pavla, Brouzdová, Jitka, Křen, Vladimír, Kulik, Natalia, Stütz, Arnold E., Thonhofer, Martin, Wrodnigg, Tanja M.

Source: In Bioorganic Chemistry July 2024 148

Glycomimetic inhibitors of tandem-repeat galectins: Simple and efficient

Authors: Vrbata, David, Červený, Jakub, Kulik, Natalia, Hovorková, Michaela, Balogová, Soňa, Vlachová, Miluše, Pelantová, Helena, Křen, Vladimír, Bojarová, Pavla

Source: In Bioorganic Chemistry April 2024 145

Heterologous expression, purification and characterization of nitrilase from Aspergillus niger K10

Authors: Felsberg Jürgen, Cantarella Maria, Slámová Kristýna, Rinágelová Anna, Veselá Alicja B, Šveda Ondřej, Malandra Anna, Benada Oldřich, Kavan Daniel, Vaněk Ondřej, Kulik Natallia, Ettrich Rüdiger, Plíhal Ondřej, Bezouška Karel, Kaplan Ondřej, Dušková Jarmila, Dohnálek Jan, Kotik Michael, Křen Vladimír, Martínková Ludmila

Source: BMC Biotechnology, Vol 11, Iss 1, p 2 (2011)

Subject Terms: Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: http://www.biomedcentral.com/1472-6750/11/2; https://doaj.org/toc/1472-6750

Access URL: https://doaj.org/article/32809d8c26604d979fd58102f928990c

Pharmacogenetic interaction between dexamethasone and Cd36-deficient segment of spontaneously hypertensive rat chromosome 4 affects triacylglycerol and cholesterol distribution into lipoprotein fractions

Authors: Křen Vladimír, Křenová Drahomíra, Liška František, Šedová Lucie, Krupková Michaela, Šeda Ondřej

Source: Lipids in Health and Disease, Vol 9, Iss 1, p 38 (2010)

Subject Terms: Nutritional diseases. Deficiency diseases, RC620-627

File Description: electronic resource

Relation: http://www.lipidworld.com/content/9/1/38; https://doaj.org/toc/1476-511X

Access URL: https://doaj.org/article/67e2aa3b3af94ea4bc3d417ddde343a2

Galectin-targeting glycocalix[4]arenes can enter the cellsElectronic supplementary information (ESI) available: Detailed information on materials and methods, synthetic procedures, affinity and biodistribution experiments, western blot and qPCR, structural characterization of compounds – data and spectra. See DOI: https://doi.org/10.1039/d3cc02905k

Authors: Vlachová, Miluše, Tran, Van Nguyen, Červený, Jakub, Dolníček, František, Petrásková, Lucie, Pelantová, Helena, Kundrát, Ondřej, Cvačka, Josef, Bosáková, Zuzana, Křen, Vladimír, Lhoták, Pavel, Viktorová, Jitka, Bojarová, Pavla

Source: Chemical communications. 59(69):10404-10407

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190923859.0x000001&indx=1&recIds=ETOCvdc_100190923859.0x000001

Glycocalix[4]arenes and their affinity to a library of galectins: the linker mattersElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d2ob02235d

Authors: Konvalinková, Dorota, Dolníček, František, Hovorková, Michaela, Červený, Jakub, Kundrát, Ondřej, Pelantová, Helena, Petrásková, Lucie, Cvačka, Josef, Faizulina, Margarita, Varghese, Beena, Kovaříček, Petr, Křen, Vladimír, Lhoták, Pavel, Bojarová, Pavla

Source: Organic & biomolecular chemistry. 21(6):1294-1302

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178333582.0x000001&indx=1&recIds=ETOCvdc_100178333582.0x000001

Highly functionalized diaminocyclopentanes: A new route to potent and selective inhibitors of human O-GlcNAcase

Authors: Weber, Patrick, Mészáros, Zuzana, Bojarová, Pavla, Ebner, Manuel, Fischer, Roland, Křen, Vladimír, Kulik, Natalia, Müller, Philipp, Vlachová, Miluše, Slámová, Kristýna, Stütz, Arnold E., Thonhofer, Martin, Torvisco, Ana, Wrodnigg, Tanja M., Wolfsgruber, Andreas

Source: In Bioorganic Chemistry November 2023 140

Advanced high-affinity glycoconjugate ligands of galectins

Authors: Hovorková, Michaela, Červený, Jakub, Bumba, Ladislav, Pelantová, Helena, Cvačka, Josef, Křen, Vladimír, Renaudet, Olivier, Goyard, David, Bojarová, Pavla

Source: In Bioorganic Chemistry February 2023 131

Metabolic profiling of silymarin constituents in urine and feces of healthy volunteers: A 90-day study

Authors: Lněničková, Kateřina, Vrba, Jiří, Kosina, Pavel, Papoušková, Barbora, Mekadim, Chahrazed, Mrázek, Jakub, Sova, Milan, Sovová, Eliška, Valentová, Kateřina, Křen, Vladimír, Kouřilová, Pavla, Vrbková, Jana, Ulrichová, Jitka

Source: In Journal of Functional Foods January 2023 100

Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer’s disease

Authors: Velueta-Viveros, Martha, Martínez-Bailén, Macarena, Puerta, Adrián, Romero-Hernández, Laura L., Křen, Vladimír, Merino-Montiel, Penélope, Montiel-Smith, Sara, Fernandes, Miguel X., Moreno-Vargas, Antonio J., Padrón, José M., López, Óscar, Fernández-Bolaños, José G.

Source: In Bioorganic Chemistry October 2022 127

Hypertransglycosylating Variants of the GH20 β‐N‐Acetylhexosaminidase for the Synthesis of Chitooligomers

Authors: Mészáros, Zuzana, Petrásková, Lucie, Kulik, Natalia, Pelantová, Helena, Bojarová, Pavla, Křen, Vladimír, Slámová, Kristýna

Source: Advanced synthesis & catalysis. 364(12):2009-2022

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100153532664.0x000001&indx=1&recIds=ETOCvdc_100153532664.0x000001

Silybin and its congeners: from traditional medicine to molecular effectsThis review is dedicated to the memory of Prof. em. Dr. Dr. h.c. mult. Hildebert Wagner, one of the founders of silymarin research, who passed away on November 5, 2021, at the age of 92.

Authors: Křen, Vladimír, Valentová, Kateřina

Source: Natural product reports. 39(6):1264-1281

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100153399610.0x000001&indx=1&recIds=ETOCvdc_100153399610.0x000001

Interaction of Flavonoids with Zinc and Zinc-Containing Enzymes

Authors: Hrubša, Marcel, Tvrdý, Václav, Kutý, Michal, Valentová, Kateřina, Křen, Vladimír, Mladěnka, Přemysl

Source: Journal of agricultural and food chemistry. 70(20):6134-6144

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN629373649&indx=1&recIds=ETOCRN629373649

Diaminocyclopentane-derived O-GlcNAcase inhibitors for combating tau hyperphosphorylation in Alzheimer's diseaseElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d2cc02712g

Authors: Weber, Patrick, Mészáros, Zuzana, Jagečić, Denis, Hribljan, Valentina, Mitrečić, Dinko, Bojarová, Pavla, Slámová, Kristýna, Vrba, Jiří, Kulik, Natalia, Křen, Vladimír, Stütz, Arnold E.

Source: Chemical communications. 58(63):8838-8841

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157266441.0x000001&indx=1&recIds=ETOCvdc_100157266441.0x000001

Color-coded galectin fusion proteins as novel tools in biomaterial science.

Authors: Dey, Carina, Sommerfeld, Isabel K., Bojarová, Pavla, Kodra, Nikol, Vrbata, David, Zimolová Vlachová, Miluše, Křen, Vladimír, Pich, Andrij, Elling, Lothar

Source: Biomaterials Science (2047-4830); 3/21/2025, Vol. 13 Issue 6, p1482-1500, 19p

Carbon Monoxide-Releasing Activity of Plant Flavonoids.

Authors: Muchová, Lucie, Šranková, Mária, Balasubramani, Sriram, Mehta, Panshul, Vlachopoulou, Dafni, Kapoor, Akshat, Ramundo, Andrea, Jézéquel, Yann Anton, Bożek, Igor, Hurtová, Martina, Klán, Petr, Křen, Vladimír, Vítek, Libor

Source: Journal of Agricultural & Food Chemistry; 1/15/2024, Vol. 73 Issue 2, p1308-1318, 11p

Flavonolignans from silymarin modulate antibiotic resistance and virulence in Staphylococcus aureus

Authors: Holasová, Kateřina, Křížkovská, Bára, Hoang, Lan, Dobiasová, Simona, Lipov, Jan, Macek, Tomáš, Křen, Vladimír, Valentová, Kateřina, Ruml, Tomáš, Viktorová, Jitka

Source: In Biomedicine & Pharmacotherapy May 2022 149

Discovery of human hexosaminidase inhibitors by in situ screening of a library of mono- and divalent pyrrolidine iminosugars

Authors: Pingitore, Valeria, Martínez-Bailén, Macarena, Carmona, Ana T., Mészáros, Zuzana, Kulik, Natalia, Slámová, Kristýna, Křen, Vladimír, Bojarová, Pavla, Robina, Inmaculada, Moreno-Vargas, Antonio J.

Source: In Bioorganic Chemistry March 2022 120