Enhancing T cell cytotoxicity in multiple myeloma with bispecific αPD-L1 × αCD3 T cell engager-armed T cells and low-dose bortezomib therapy

Authors: Sawasdee, Nunghathai ^{a, b, 1}, Thepmalee, Chutamas ^{c, 1}, Junking, Mutita ^{a, b}, Okada, Seiji ^d, Panya, Aussara ^{e, f, ⁎}, Yenchitsomanus, Pa-thai ^{a, b, ⁎⁎}

Source: In Biomedicine & Pharmacotherapy March 2025 184

Precision immunotherapy for cholangiocarcinoma: Pioneering the use of human-derived anti-cMET single chain variable fragment in anti-cMET chimeric antigen receptor (CAR) NK cells

Authors: Chiawpanit, Chutipa, Wathikthinnakorn, Methi, Sawasdee, Nunghathai, Phanthaphol, Nattaporn, Sujjitjoon, Jatuporn, Junking, Mutita, Yamabhai, Montarop, Panaampon, Jutatip, Yenchitsomanus, Pa-thai, Panya, Aussara

Source: In International Immunopharmacology 30 July 2024 136

Bispecific T cell engager-armed T cells targeting integrin ανβ6 exhibit enhanced T cell redirection and antitumor activity in cholangiocarcinoma

Authors: Suwanchiwasiri, Kwanpirom ^{a, b, c}, Phanthaphol, Nattaporn ^{b, c, d, ⁎}, Somboonpatarakun, Chalermchai ^{b, c}, Yuti, Pornpimon ^{b, c}, Sujjitjoon, Jatuporn ^{b, c}, Luangwattananun, Piriya ^{b, c}, Maher, John ^e, Yenchitsomanus, Pa‑thai ^{b, c}, Junking, Mutita ^{b, c, ⁎⁎}

Source: In Biomedicine & Pharmacotherapy June 2024 175

Cytotoxicity of fourth-generation anti-Trop2 CAR-T cells against breast cancer

Authors: Somboonpatarakun, Chalermchai, Phanthaphol, Nattaporn, Suwanchiwasiri, Kwanpirom, Ramwarungkura, Boonyanuch, Yuti, Pornpimon, Poungvarin, Naravat, Thuwajit, Peti, Junking, Mutita, Yenchitsomanus, Pa-thai

Source: In International Immunopharmacology 10 March 2024 129

Anti-PD-L1 × anti-CD3 bispecific T-cell engager-armed T cells can overcome immunosuppression and redirect T cells to kill breast cancer cells expressing PD-L1

Authors: Luangwattananun, Piriya, Sangsuwannukul, Thanich, Supimon, Kamonlapat, Thuwajit, Chanitra, Chieochansin, Thaweesak, Sa-nguanraksa, Doonyapat, Samarnthai, Norasate, O-Charoenrat, Pornchai, Junking, Mutita, Yenchitsomanus, Pa-thai

Source: In International Immunopharmacology November 2023 124 Part B

Cytotoxic activity of anti-mucin 1 chimeric antigen receptor T cells expressing PD-1-CD28 switch receptor against cholangiocarcinoma cells

Authors: Supimon, Kamonlapat, Sangsuwannukul, Thanich, Sujjitjoon, Jatuporn, Chieochansin, Thaweesak, Junking, Mutita, Yenchitsomanus, Pa-thai

Source: In Cytotherapy February 2023 25(2):148-161

Anti-CD19 chimeric antigen receptor T cells secreting anti-PD-L1 single-chain variable fragment attenuate PD-L1 mediated T cell inhibition

Authors: Yuti, Pornpimon, Wutti-in, Yupanun, Sawasdee, Nunghathai, Kongkhla, Katesara, Phanthaphol, Nattaporn, Choomee, Kornkan, Chieochansin, Thaweesak, Panya, Aussara, Junking, Mutita, Yenchitsomanus, Pa-thai, Sujjitjoon, Jatuporn

Source: In International Immunopharmacology December 2022 113 Part B

Activation of cytotoxic T lymphocytes by self-differentiated myeloid-derived dendritic cells for killing breast cancer cells expressing folate receptor alpha protein

Authors: Luangwattananun, Piriya, Chiraphapphaiboon, Wannasiri, Thuwajit, Chanitra, Junking, Mutita, Yenchitsomanus, Pa-Thai

Source: Bioengineered. 13(6):14188-14203

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100180564295.0x000001&indx=1&recIds=ETOCvdc_100180564295.0x000001

Piperine suppresses growth and migration of human breast cancer cells through attenuation of Rac1 expression

Authors: Buranrat, Benjaporn, Junking, Mutita

Source: Asian Pacific journal of tropical biomedicine. 12(1):39-46

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139270785.0x000001&indx=1&recIds=ETOCvdc_100139270785.0x000001

Engineered T cells secreting αB7-H3-αCD3 bispecific engagers for enhanced anti-tumor activity against B7-H3 positive multiple myeloma: a novel therapeutic approach.

Authors: Rujirachaivej, Punchita, Siriboonpiputtana, Teerapong, Choomee, Kornkan, Supimon, Kamonlapat, Sangsuwannukul, Thanich, Songprakhon, Pucharee, Natungnuy, Krissada, Luangwattananun, Piriya, Yuti, Pornpimon, Junking, Mutita, Yenchitsomanus, Pa-thai

Source: Journal of Translational Medicine; 1/13/2025, Vol. 23 Issue 1, p1-19, 19p

Subject Terms: PLASMA cells, T cells, CHIMERIC antigen receptors, CYTOTOXINS, TUMOR antigens

Gemcitabine enhances cytotoxic activity of effector T-lymphocytes against chemo-resistant cholangiocarcinoma cells

Authors: Sawasdee, Nunghathai, Thepmalee, Chutamas, Sujjitjoon, Jatuporn, Yongpitakwattana, Petlada, Junking, Mutita, Poungvarin, Naravat, Yenchitsomanus, Pa-thai, Panya, Aussara

Source: In International Immunopharmacology January 2020 78

Suppression of TGF-β and IL-10 receptors on self-differentiated dendritic cells by short-hairpin RNAs enhanced activation of effector T-cells against cholangiocarcinoma cells

Authors: Thepmalee, Chutamas, Panya, Aussara, Sujjitjoon, Jatuporn, Sawasdee, Nunghathai, Poungvarin, Naravat, Junking, Mutita, Yenchitsomanus, Pa-Thai

Source: Human vaccines & immunotherapeutics. 16(10):2318-2327

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123457968.0x000001&indx=1&recIds=ETOCvdc_100123457968.0x000001

Inhibition of dengue virus replication in monocyte-derived dendritic cells by vivo-morpholino oligomers

Authors: Phumesin, Patta, Junking, Mutita, Panya, Aussara, Yongpitakwattana, Petlada, Noisakran, Sansanee, Limjindaporn, Thawornchai, Yenchitsomanus, Pa-thai

Source: VIRUS RESEARCH. 260:123-128

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117699372.0x000001&indx=1&recIds=ETOCvdc_100117699372.0x000001

Cytolytic Activity of Effector T-lymphocytes Against Hepatocellular Carcinoma is Improved by Dendritic Cells Pulsed with Pooled Tumor Antigens

Authors: Chieochansin, Thaweesak, Thepmalee, Chutamas, Grainok, Janya, Junking, Mutita, Yenchitsomanus, Pa-thai

Source: Scientific reports. 9(1):1-11

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190905925.0x000001&indx=1&recIds=ETOCvdc_100190905925.0x000001

Inhibition of IL-10 and TGF-β receptors on dendritic cells enhances activation of effector T-cells to kill cholangiocarcinoma cells

Authors: Thepmalee, Chutamas, Panya, Aussara, Junking, Mutita, Chieochansin, Thaweesak, Yenchitsomanus, Pa-thai

Source: Human vaccines & immunotherapeutics. 14(6):1423-1431

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100064870600.0x000001&indx=1&recIds=ETOCvdc_100064870600.0x000001

Estradiol Prevents High Glucose-Induced β-cell Apoptosis by Decreased BTG2 Expression

Authors: Kooptiwut, Suwattanee, Kaewin, Suchada, Semprasert, Namoiy, Sujjitjoon, Jatuporn, Junking, Mutita, Suksri, Kanchana, Yenchitsomanus, Pa-thai

Source: Scientific reports. 8(1):1-11

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175117959.0x000001&indx=1&recIds=ETOCvdc_100175117959.0x000001

Loss-of-function mutations of SCN10A encoding NaV1.8 α subunit of voltage-gated sodium channel in patients with human kidney stone disease

Authors: Nettuwakul, Choochai, Praditsap, Oranud, Sawasdee, Nunghathai, Rungroj, Nanyawan, Ruamyod, Katesirin, Watanapa, Wattana, Junking, Mutita, Sangnual, Sittideth, Sritippayawan, Suchai, Cheunsuchon, Boonyarit, Chuawattana, Duangporn, Rojsatapong, Santi, Chaowagul, Wipada, Dib-Hajj, Sulayman, Waxman, Stephen, Yenchitsomanus, Pa-thai

Source: Scientific reports. 8(1):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171374600.0x000001&indx=1&recIds=ETOCvdc_100171374600.0x000001

Cytotoxic activity of effector T cells against cholangiocarcinoma is enhanced by self-differentiated monocyte-derived dendritic cells

Authors: Panya, Aussara, Thepmalee, Chutamas, Sawasdee, Nunghathai, Sujjitjoon, Jatuporn, Phanthaphol, Nattaporn, Junking, Mutita, Wongkham, Sopit, Yenchitsomanus, Pa-thai

Source: Cancer immunology, immunotherapy. 67(10):1579-1588

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125517169.0x000001&indx=1&recIds=ETOCvdc_100125517169.0x000001

Identification of HLA‐restricted Cytotoxic T Lymphocyte Epitopes of B Cell Maturation Antigen as Promising Peptide Vaccine Candidates for Preventive and Therapeutic Strategies in Multiple Myeloma.

Authors: Chiraphapphaiboon, Wannasiri, Luangwattananun, Piriya, Chieochansin, Thaweesak, Samutpradit, Danai, Hengswat, Pranaidej, Areesawangkit, Phurin, Phikulsod, Ployploen, Sumransub, Nuttavut, Sukpanichnant, Sunya, Junking, Mutita, Yenchitsomanus, Pa‐thai

Source: Advanced Therapeutics; Feb2024, Vol. 7 Issue 2, p1-14, 14p

Therapeutic potential of third-generation chimeric antigen receptor T cells targeting B cell maturation antigen for treating multiple myeloma.

Authors: Rujirachaivej, Punchita, Siriboonpiputtana, Teerapong, Luangwattananun, Piriya, Yuti, Pornpimon, Wutti-in, Yupanun, Choomee, Kornkan, Sujjitjoon, Jatuporn, Chareonsirisuthigul, Takol, Rerkamnuaychoke, Budsaba, Junking, Mutita, Yenchitsomanus, Pa-thai

Source: Clinical & Experimental Medicine; 2024, Vol. 24 Issue 1, p1-17, 17p