Genetic and epigenetic regulation of Treg cell fitness by autism-related chromatin remodeler CHD8

Authors: Jun-Qi Yang, Chen Wang, Ramesh C. Nayak, Manohar Kolla, Mingjun Cai, Mario Pujato, Yi Zheng, Q. Richard Lu, Fukun Guo

Source: Cellular & Molecular Biology Letters, Vol 30, Iss 1, Pp 1-21 (2025)

Subject Terms: CHD8, Treg, Treg plasticity, Chromatin remodeling, Gene expression, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1689-1392

Access URL: https://doaj.org/article/9f3448b5ac114c8c85adde59404dbde1

Mechanism of inert inflammation in an immune checkpoint blockade-resistant tumor subtype bearing transcription elongation defects

Authors: Vishnu Modur, Belal Muhammad, Jun-Qi Yang, Yi Zheng, Kakajan Komurov, Fukun Guo

Source: Cell Reports, Vol 42, Iss 4, Pp 112364- (2023)

Subject Terms: CP: Cancer, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124723003753; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/fda98c52b17248c99d73d17a3352df8d

Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity

Authors: Yuan Li, Yi Zheng, Phuong Nguyen, Ting Wen, Anil G Jegga, Khalid W Kalim, Jun-Qi Yang, Mark Wunderlich, Vishnu Modur, Ashley Kuenzi Davis, Ravinder Verma, Qing Richard Lu, Fukun Guo

Source: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 11 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/10/11/e004806.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/0a852aedcfe146eb8f5e7e1f97e9c4cf

Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity

Authors: Khalid W. Kalim, Jun-Qi Yang, Vishnu Modur, Phuong Nguyen, Yuan Li, Yi Zheng, Fukun Guo

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: RhoA, Treg cells, effector T cells, autoimmunity, tumor immunity, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.726393/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/7361ff77742f4a8e83b141d2bb18f362

Correction: Schistosoma japonicum infection downregulates house dust mite-induced allergic airway inflammation in mice.

Authors: Sugan Qiu, Xiaolin Fan, Yingying Yang, Panpan Dong, Wei Zhou, Yongliang Xu, Yonghua Zhou, Fukun Guo, Yi Zheng, Jun-Qi Yang

Source: PLoS ONE, Vol 13, Iss 1, p e0190996 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5756046?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/4c1e0c94fdc24265ba8099bbe919b368

Inhibition of Rho-Kinase Downregulates Th17 Cells and Ameliorates Hepatic Fibrosis by Schistosoma japonicum Infection

Authors: Wei Zhou, Yingying Yang, Congjin Mei, Panpan Dong, Shasha Mu, Hongchu Wu, Yonghua Zhou, Yi Zheng, Fukun Guo, Jun-Qi Yang

Source: Cells, Vol 8, Iss 10, p 1262 (2019)

Subject Terms: rhoa-rock, fasudil, th17, schistosoma japonicum, hepatic fibrosis, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/8/10/1262; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/60fc06fbc50947d086605913c2fe1ceb

Schistosoma japonicum infection downregulates house dust mite-induced allergic airway inflammation in mice.

Authors: Sugan Qiu, Xiaolin Fan, Yingying Yang, Panpan Dong, Wei Zhou, Yongliang Xu, Yonghua Zhou, Fukun Guo, Yi Zheng, Jun-Qi Yang

Source: PLoS ONE, Vol 12, Iss 6, p e0179565 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5470717?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e880fc38f7af4e55aa0eed052b66b8e2

mTOR has a developmental stage-specific role in mitochondrial fitness independent of conventional mTORC1 and mTORC2 and the kinase activity.

Authors: Khalid W Kalim, Shuangmin Zhang, Xiaoyi Chen, Yuan Li, Jun-Qi Yang, Yi Zheng, Fukun Guo

Source: PLoS ONE, Vol 12, Iss 8, p e0183266 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5558967?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e02f431e4fd24be18ae525664dfd872f

Effects of Invariant NKT Cells on Parasite Infections and Hygiene Hypothesis

Authors: Jun-Qi Yang, Yonghua Zhou, Ram Raj Singh

Source: Journal of Immunology Research, Vol 2016 (2016)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2314-8861; https://doaj.org/toc/2314-7156

Access URL: https://doaj.org/article/c9cc46c49ee643c4bcb2d711f2d9922c

Homeostatic regulation of marginal zone B cells by invariant natural killer T cells.

Authors: Xiangshu Wen, Jun-Qi Yang, Peter J Kim, Ram Raj Singh

Source: PLoS ONE, Vol 6, Iss 10, p e26536 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3202546?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/3a77ff2020e248a7bfaea01b26896121

Reciprocal Regulation of Glycolysis-Driven Th17 Pathogenicity and Regulatory T Cell Stability by Cdc42.

Authors: Kalim, Khalid W.¹, Jun-Qi Yang^1,2, Yuan Li¹, Yan Meng^1,3, Yi Zheng¹, Fukun Guo¹ fukun.guo@cchmc.org

Source: Journal of Immunology. 4/1/2018, Vol. 200 Issue 7, p2313-2326. 14p.

Subject Terms: *T cells, *GLYCOLYSIS, *MICROBIAL virulence, *AUTOIMMUNE diseases, *IMMUNOLOGICAL tolerance, *IMMUNITY

Study on Indicators Forecasting Model of Regional Economic Development Based on Neural Network.

Authors: Jun-qi, Yang, -xia, Gao, Li-jia, Chen

Source: Nanomaterials & Nanoarchitectures; 2011, p297-304, 8p

Gene Targeting RhoA Reveals Its Essential Role in Coordinating Mitochondrial Function and Thymocyte Development.

Authors: Shuangmin Zhang, Konstantinidis, Diamantis G., Jun-Qi Yang, Mizukawa, Benjamin, Kalim, Khalid, Lang, Richard A., Kalfa, Theodosia A., Yi Zheng, Fukun Guo

Source: Journal of Immunology; 12/15/2014, Vol. 193 Issue 12, p5973-5982, 10p

Germline deletion of β2 microglobulin or CD1d reduces anti-phospholipid antibody, but increases autoantibodies against non-phospholipid antigens in the NZB/W F1 model of lupus.

Authors: Singh, Ram Raj, Jun-Qi Yang, Kim, Peter J., Halder, Ramesh C.

Source: Arthritis Research & Therapy; 2013, Vol. 15 Issue 2, preceding p1-10, 11p, 1 Color Photograph, 1 Diagram, 6 Graphs

Invariant NKT Cells Inhibit Autoreactive B Cells in a Contact- and CD1d-Dependent Manner.

Authors: Jun-Qi Yang^1,2,3, Xiangshu Wen¹, Kim, Peter J.¹, Singh, Ram Raj^1,2,4,5

Source: Journal of Immunology. 2/1/2011, Vol. 186 Issue 3, p1512-1520. 9p.

Subject Terms: *B cells, *IMMUNOSUPPRESSION, *CELLULAR control mechanisms, *MACROPHAGE activation, *CYTOKINES, *AUTOIMMUNE diseases

NBR1 is a new PB1 signalling adapter in Th2 differentiation and allergic airway inflammation in vivo.

Authors: Jun-Qi Yang¹, Hongzhu Liu¹, Diaz-Meco, Maria T.¹, Moscat, Jorge¹ jorge.moscat@uc.edu

Source: EMBO Journal. 10/6/2010, Vol. 29 Issue 19, p3421-3433. 13p. 7 Graphs.

Subject Terms: *AIRWAY (Anatomy), *ALLERGIES, *INFLAMMATION, *IMMUNOLOGY, *CELL polarity, *DISEASES

Loss of PKCλ/ι impairs Th2 establishment and allergic airway inflammation in vivo.

Authors: Jun-Qi Yang¹, Leitges, Michael², Duran, Angeles¹, Diaz-Meco, Maria T.¹, Moscat, Jorge¹ jorge.moscat@uc.edu

Source: Proceedings of the National Academy of Sciences of the United States of America. 1/27/2009, Vol. 106 Issue 4, p1099-1104. 6p. 6 Graphs.

Subject Terms: *T cell differentiation, *CYTOKINES, *TRANSCRIPTION factors, *T cells, *CELL growth

Examining the Role of CD1d and Natural Killer T Cells in the Development of Nephritis in a Genetically Susceptible Lupus Model.

Authors: Jun-Qi Yang¹, Xiangshu Wen², Hongzhu Liu¹, Folayan, Gbolahan², Xin Dong², Min Zhou², Van Kaer, Luc³, Singh, Ram Raj^2,4 RRSingh@mednet.ucla.edu

Source: Arthritis & Rheumatism. Apr2007, Vol. 56 Issue 4, p1219-1233. 15p. 4 Black and White Photographs, 2 Charts, 5 Graphs.

Subject Terms: *KILLER cells, *IMMUNOCOMPETENT cells, *SYSTEMIC lupus erythematosus, *AUTOIMMUNE diseases, *INTERLEUKIN-4, *T cells