Discrete and conserved inflammatory signatures drive thrombosis in different organs after Salmonella infection

Authors: Marisol Perez-Toledo, Nonantzin Beristain-Covarrubias, Jamie Pillaye, Ruby R. Persaud, Edith Marcial-Juarez, Sian E. Jossi, Jessica R. Hitchcock, Areej Alshayea, William M. Channell, Niek T. J. Wiersma, Rachel E. Lamerton, Dean P. Kavanagh, Agostina Carestia, William G. Horsnell, Ian R. Henderson, Nigel Mackman, Andrew R. Clark, Craig N. Jenne, Julie Rayes, Steve P. Watson, Adam F. Cunningham

Source: Nature Communications, Vol 16, Iss 1, Pp 1-16 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/b0dcae4efd3544f69713e7a22628e790

Modelling the pathology and treatment of cardiac fibrosis in vascularised atrial and ventricular cardiac microtissues

Authors: Jasmeet S. Reyat, Alessandro di Maio, Beata Grygielska, Jeremy Pike, Samuel Kemble, Antonio Rodriguez-Romero, Christina Simoglou Karali, Adam P. Croft, Bethan Psaila, Filipa Simões, Julie Rayes, Abdullah O. Khan

Source: Frontiers in Cardiovascular Medicine, Vol 10 (2023)

Subject Terms: 3D cardiac microtissues, induced pluripotent stem cells, tissue engineering, cardiac fibrosis, cardiomyocytes, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2023.1156759/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/3399289f4d04440a98842fe8c911f425

Megakaryocyte NLRP3 hyperactivation induces mild anemia and potentiates inflammatory response in mice

Authors: Joshua H. Bourne, Joana Campos, Sophie J. Hopkin, Katharine Whitworth, James Palis, Yotis A. Senis, Julie Rayes, Asif J. Iqbal, Alexander Brill

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: NLRP3, platelets, inflammasome, zymosan-induced peritonitis, erythropoiesis, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1226196/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/f12cd561058a4428b36a02a3bad37820

Severity of SARS-CoV-2 infection is associated with high numbers of alveolar mast cells and their degranulation

Authors: Olga Krysko, Joshua H. Bourne, Elena Kondakova, Elena A. Galova, Katharine Whitworth, Maddy L. Newby, Claus Bachert, Harriet Hill, Max Crispin, Zania Stamataki, Adam F. Cunningham, Matthew Pugh, Abdullah O. Khan, Julie Rayes, Maria Vedunova, Dmitri V. Krysko, Alexander Brill

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: COVID-19, mast cells, protease, LUVA cells, von Willebrand factor, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.968981/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/79b67959ef144c44ab258fd04a23bccb

Lymphatic blood filling in CLEC-2-deficient mouse models

Authors: Elizabeth J Haining, Kate L Lowe, Surasak Wichaiyo, Raghu P Kataru, Zoltan Nagy, Dean Pj Kavanagh, Sian Lax, Ying Di, Bernhard Nieswandt, Benoît Ho-Tin-Noé, Babak J Mehrara, Yotis A Senis, Julie Rayes, Steve P Watson

Source: Platelets, Vol 32, Iss 3, Pp 352-367 (2021)

Subject Terms: blood-lymphatic separation, clec-2, platelets, podoplanin, Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/0953-7104; https://doaj.org/toc/1369-1635

Access URL: https://doaj.org/article/a005fc05380f45788ba6052de9029753

SARS-CoV-2 Spike- and Nucleoprotein-Specific Antibodies Induced After Vaccination or Infection Promote Classical Complement Activation

Authors: Rachel E. Lamerton, Edith Marcial-Juarez, Sian E. Faustini, Marisol Perez-Toledo, Margaret Goodall, Siân E. Jossi, Maddy L. Newby, Iain Chapple, Thomas Dietrich, Tonny Veenith, Adrian M. Shields, Lorraine Harper, Ian R. Henderson, Julie Rayes, David C. Wraith, Steve P. Watson, Max Crispin, Mark T. Drayson, Alex G. Richter, Adam F. Cunningham

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: complement, COVID-19, SARS-CoV-2, vaccine, antibodies, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.838780/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/e96e183f4c0140d195866a01fcba3220

Illustrated State‐of‐the‐Art Capsules of the ISTH 2022 Congress

Authors: Robert A. Ariëns, Beverley J. Hunt, Ejaife O. Agbani, Josefin Ahnström, Robert Ahrends, Raza Alikhan, Alice Assinger, Zsuzsa Bagoly, Alessandra Balduini, Elena Barbon, Christopher D. Barrett, Paul Batty, Jorge David Aivazoglou Carneiro, Wee Shian Chan, Moniek deMaat, Kerstin deWit, Cécile Denis, Martin H. Ellis, Renee Eslick, Hongxia Fu, Catherine P. M. Hayward, Benoit Ho‐Tin‐Noé, Frederikus A. Klok, Riten Kumar, Karin Leiderman, Rustem I. Litvinov, Nigel Mackman, Zoe McQuilten, Matthew D. Neal, William A. E. Parker, Roger J. S. Preston, Julie Rayes, Alireza R. Rezaie, Lara N. Roberts, Bianca Rocca, Susan Shapiro, Deborah M. Siegal, Lirlândia P. Sousa, Katsue Suzuki‐Inoue, Tahira Zafar, Jiaxi Zhou

Source: Research and Practice in Thrombosis and Haemostasis, Vol 6, Iss 5, Pp n/a-n/a (2022)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2475-0379

Access URL: https://doaj.org/article/f79ff8eebaef425b98250762e3be6774

Platelets and Antiplatelet Medication in COVID-19-Related Thrombotic Complications

Authors: Waltraud C. Schrottmaier, Anita Pirabe, David Pereyra, Stefan Heber, Hubert Hackl, Anna Schmuckenschlager, Laura Brunnthaler, Jonas Santol, Kerstin Kammerer, Justin Oosterlee, Erich Pawelka, Sonja M. Treiber, Abdullah O. Khan, Matthew Pugh, Marianna T. Traugott, Christian Schörgenhofer, Tamara Seitz, Mario Karolyi, Bernd Jilma, Julie Rayes, Alexander Zoufaly, Alice Assinger

Source: Frontiers in Cardiovascular Medicine, Vol 8 (2022)

Subject Terms: COVID-19, infection, platelet, platelet dysfunction, microthrombi, anti-platelet therapy, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2021.802566/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/aa45ea165912461dbabdad4a74abcca7

Adverse Outcome in COVID-19 Is Associated With an Aggravating Hypo-Responsive Platelet Phenotype

Authors: Waltraud C. Schrottmaier, Anita Pirabe, David Pereyra, Stefan Heber, Hubert Hackl, Anna Schmuckenschlager, Laura Brunnthaler, Jonas Santol, Kerstin Kammerer, Justin Oosterlee, Erich Pawelka, Sonja M. Treiber, Abdullah O. Khan, Matthew Pugh, Marianna T. Traugott, Christian Schörgenhofer, Tamara Seitz, Mario Karolyi, Bernd Jilma, Julie Rayes, Alexander Zoufaly, Alice Assinger

Source: Frontiers in Cardiovascular Medicine, Vol 8 (2021)

Subject Terms: COVID-19, platelet, infection, platelet dysfunction, platelet-leukocyte interaction, outcome, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2021.795624/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/95669424e98c45f4b6455fb6feb38854

The dual role of platelet‐innate immune cell interactions in thrombo‐inflammation

Authors: Julie Rayes, Joshua H. Bourne, Alexander Brill, Steve P. Watson

Source: Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 1, Pp 23-35 (2020)

Subject Terms: immune cells, inflammation, platelets, thrombo‐inflammation, thrombosis, Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2475-0379

Access URL: https://doaj.org/article/c7ec012f308a4eb1861951ab4c9a7ff8

CLEC-2 Prevents Accumulation and Retention of Inflammatory Macrophages During Murine Peritonitis

Authors: Joshua H. Bourne, Nonantzin Beristain-Covarrubias, Malou Zuidscherwoude, Joana Campos, Ying Di, Evelyn Garlick, Martina Colicchia, Lauren V. Terry, Steven G. Thomas, Alexander Brill, Jagadeesh Bayry, Steve P. Watson, Julie Rayes

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: CLEC-2, podoplanin, macrophage, inflammation, platelet, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.693974/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/b064efb78360449f877099d157169844

Post-translational polymodification of β1-tubulin regulates motor protein localization in platelet production and function

Authors: Abdullah O. Khan, Alexandre Slater, Annabel Maclachlan, Phillip L.R. Nicolson, Jeremy A. Pike, Jasmeet S. Reyat, Jack Yule, Rachel Stapley, Julie Rayes, Steven G. Thomas, Neil V. Morgan

Source: Haematologica, Vol 107, Iss 1 (2020)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10119; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/499818eef52141fda25ba5aa4841cfc0

Platelets: bridging thrombosis and inflammation

Authors: Julie Rayes, Craig N Jenne

Source: Platelets, Vol 32, Iss 3, Pp 293-294 (2021)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/0953-7104; https://doaj.org/toc/1369-1635

Access URL: https://doaj.org/article/e28c5329c4554a0482afaec289311b4a

The podoplanin-CLEC-2 axis inhibits inflammation in sepsis

Authors: Julie Rayes, Siân Lax, Surasak Wichaiyo, Stephanie K. Watson, Ying Di, Stephanie Lombard, Beata Grygielska, Stuart W. Smith, Kassiani Skordilis, Steve P. Watson

Source: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/b4f263bdafe34009bf6c603e5a0f07a4

Heme induces human and mouse platelet activation through C-type-lectin-like receptor-2

Authors: Joshua H. Bourne, Martina Colicchia, Ying Di, Eleyna Martin, Alexander Slater, Lubka T. Roumenina, Jordan D. Dimitrov, Steve P. Watson, Julie Rayes

Source: Haematologica, Vol 106, Iss 2 (2020)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/9735; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/916d3ac7c2d44338bfa3612fd4de904c

Removal of Mannose-Ending Glycan at Asn2118 Abrogates FVIII Presentation by Human Monocyte-Derived Dendritic Cells

Authors: Sandrine Delignat, Julie Rayes, Suryasarathi Dasgupta, Bagirath Gangadharan, Cécile V. Denis, Olivier D. Christophe, Jagadeesh Bayry, Srinivas V. Kaveri, Sébastien Lacroix-Desmazes

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: hemophilia A, factor VIII, FVIII inhibitors, N-glycosylations, immunogenicity of therapeutic proteins, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.00393/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/56cbe631476a4dda8386f9a407c8d613

Platelet glycoprotein VI and C-type lectin-like receptor 2 deficiency accelerates wound healing by impairing vascular integrity in mice

Authors: Surasak Wichaiyo, Sian Lax, Samantha J. Montague, Zhi Li, Beata Grygielska, Jeremy A. Pike, Elizabeth J. Haining, Alexander Brill, Steve P. Watson, Julie Rayes

Source: Haematologica, Vol 104, Iss 8 (2019)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/9014; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/a5b1b1ff5b2c4c9e817869ca2c198e0a

Platelets in Sepsis: An Update on Experimental Models and Clinical Data

Authors: Alice Assinger, Waltraud C. Schrottmaier, Manuel Salzmann, Julie Rayes

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: sepsis, inflammation, platelets, thrombocytopenia, infection, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.01687/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/badbb769371b45c8a81d853e6277677b

Prevention of the anti-factor VIII memory B-cell response by inhibition of Bruton tyrosine kinase in experimental hemophilia A

Authors: Sandrine Delignat, Jules Russick, Bagirath Gangadharan, Julie Rayes, Mathieu Ing, Jan Voorberg, Srinivas V. Kaveri, Sébastien Lacroix-Desmazes

Source: Haematologica, Vol 104, Iss 5 (2019)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/8880; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/497a1764d881450494885fc6b6e0fcf9

Risk stratification integrating genetic data for factor VIII inhibitor development in patients with severe hemophilia A.

Authors: Delphine Bachelet, Thilo Albert, Cyprien Mbogning, Signe Hässler, Yuan Zhang, Stephan Schultze-Strasser, Yohann Repessé, Julie Rayes, Anna Pavlova, Behnaz Pezeshkpoor, Kerstin Liphardt, Julie E Davidson, Agnès Hincelin-Méry, Pierre Dönnes, Sébastien Lacroix-Desmazes, Christoph Königs, Johannes Oldenburg, Philippe Broët, ABIRISK consortium

Source: PLoS ONE, Vol 14, Iss 6, p e0218258 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e167617cea974ae693edaf5a173d15e0