Recent advances of small extracellular vesicle biomarkers in breast cancer diagnosis and prognosis

Authors: Yujin Lee, Jie Ni, Julia Beretov, Valerie C. Wasinger, Peter Graham, Yong Li

Source: Molecular Cancer, Vol 22, Iss 1, Pp 1-22 (2023)

Subject Terms: Breast cancer, Extracellular vesicles, Liquid biopsy, Biomarker, Diagnosis, Prognosis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/1eb300aa2c324003b71d4dda3cc4716e

Survival prediction in triple negative breast cancer using multiple instance learning of histopathological images

Authors: Piumi Sandarenu, Ewan K. A. Millar, Yang Song, Lois Browne, Julia Beretov, Jodi Lynch, Peter H. Graham, Jitendra Jonnagaddala, Nicholas Hawkins, Junzhou Huang, Erik Meijering

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/f4c314d9cc1a4265a0a2e2bc087eee51

Multiplexed immunofluorescence identifies high stromal CD68+PD-L1+ macrophages as a predictor of improved survival in triple negative breast cancer

Authors: James Wang, Lois Browne, Iveta Slapetova, Fei Shang, Kirsty Lee, Jodi Lynch, Julia Beretov, Renee Whan, Peter H. Graham, Ewan K. A. Millar

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/34c61617586b40f799dbf32a01b62a1c

Immunotherapy for triple-negative breast cancer: A molecular insight into the microenvironment, treatment, and resistance

Authors: Xupeng Bai, Jie Ni, Julia Beretov, Peter Graham, Yong Li

Source: Journal of the National Cancer Center, Vol 1, Iss 3, Pp 75-87 (2021)

Subject Terms: Triple-negative breast cancer, Microenvironment, Immunotherapy, Immunotherapeutic resistance, Immune checkpoint, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2667005421000296; https://doaj.org/toc/2667-0054

Access URL: https://doaj.org/article/b70b5e3637074d7693e3d1e8c38ef8fc

Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis

Authors: Sunny Z. Wu, Daniel L. Roden, Ghamdan Al-Eryani, Nenad Bartonicek, Kate Harvey, Aurélie S. Cazet, Chia-Ling Chan, Simon Junankar, Mun N. Hui, Ewan A. Millar, Julia Beretov, Lisa Horvath, Anthony M. Joshua, Phillip Stricker, James S. Wilmott, Camelia Quek, Georgina V. Long, Richard A. Scolyer, Bertrand Z. Yeung, Davendra Segara, Cindy Mak, Sanjay Warrier, Joseph E. Powell, Sandra O’Toole, Elgene Lim, Alexander Swarbrick

Source: Genome Medicine, Vol 13, Iss 1, Pp 1-17 (2021)

Subject Terms: Single-cell RNA sequencing, Cryopreservation, Tumour heterogeneity, CITE-Seq, Breast cancer, Prostate cancer, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/a5ef0303cd954e8fa8a1cccb863078c6

ALTEN: A High‐Fidelity Primary Tissue‐Engineering Platform to Assess Cellular Responses Ex Vivo

Authors: Andrew M. K. Law, Jiamin Chen, Yolanda Colino‐Sanguino, Laura Rodriguez de la Fuente, Guocheng Fang, Susan M. Grimes, Hongxu Lu, Robert J. Huang, Sarah T. Boyle, Jeron Venhuizen, Lesley Castillo, Javad Tavakoli, Joanna N. Skhinas, Ewan K. A. Millar, Julia Beretov, Fernando J. Rossello, Joanne L. Tipper, Christopher J. Ormandy, Michael S. Samuel, Thomas R. Cox, Luciano Martelotto, Dayong Jin, Fatima Valdes‐Mora, Hanlee P. Ji, David Gallego‐Ortega

Source: Advanced Science, Vol 9, Iss 21, Pp n/a-n/a (2022)

Subject Terms: alginate, ex vivo drug screening, single‐cell RNAseq, three dimensional culture, tissue microenvironment, whole‐tissue organoids, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/7c01605cf8c442bb9c5423b06b6545f3

THOC2 and THOC5 Regulate Stemness and Radioresistance in Triple‐Negative Breast Cancer

Authors: Xupeng Bai, Jie Ni, Julia Beretov, Shanping Wang, Xingli Dong, Peter Graham, Yong Li

Source: Advanced Science, Vol 8, Iss 24, Pp n/a-n/a (2021)

Subject Terms: cancer stem cells, NANOG, radioresistance, SOX2, THO2, THOC5, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/d968483f6a564190a86e35beeb3423ba

Inhibition of PI3K/Akt/mTOR signaling pathway alleviates ovarian cancer chemoresistance through reversing epithelial-mesenchymal transition and decreasing cancer stem cell marker expression

Authors: Junli Deng, Xupeng Bai, Xiaojie Feng, Jie Ni, Julia Beretov, Peter Graham, Yong Li

Source: BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)

Subject Terms: Ovarian cancer, Chemoresistance, EMT, CSC, PI3K/Akt/mTOR signaling, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-019-5824-9; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/6022d057b5764914a7dcd393c4b0c5a1

Activation of the eIF2α/ATF4 axis drives triple-negative breast cancer radioresistance by promoting glutathione biosynthesis

Authors: Xupeng Bai, Jie Ni, Julia Beretov, Valerie C. Wasinger, Shanping Wang, Ying Zhu, Peter Graham, Yong Li

Source: Redox Biology, Vol 43, Iss , Pp 101993- (2021)

Subject Terms: TNBC, Radioresistance, Integrated stress response, eIF2α, ATF4, GSH, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231721001518; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/5351fa2896364b44af6f25771bca60f1

Fecal DNA Virome Is Associated with the Development of Colorectal Neoplasia in a Murine Model of Colorectal Cancer

Authors: Yingshi Li, Fan Zhang, Huimin Zheng, Sanjna Kalasabail, Chloe Hicks, Ka Yee Fung, Adele Preaudet, Tracy Putoczki, Julia Beretov, Ewan K. A. Millar, Emad El-Omar, Xiao-Tao Jiang, Howard Chi Ho Yim

Source: Pathogens, Vol 11, Iss 4, p 457 (2022)

Subject Terms: bacteriophage, colorectal neoplasia, virome, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/11/4/457; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/4947a9ec101b4ab9a7c16332933b2784

Epithelial cell adhesion molecule (EpCAM) is involved in prostate cancer chemotherapy/radiotherapy response in vivo

Authors: Jie Ni, Paul Cozzi, Julia Beretov, Wei Duan, Joseph Bucci, Peter Graham, Yong Li

Source: BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)

Subject Terms: EpCAM, Prostate cancer, Animal model, PI3K/Akt/mTOR signaling pathway, Chemoresistance, Radioresistance, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-018-5010-5; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/99b65e59d5a94b44999adb7744cea52b

CHTOP in Chemoresistant Epithelial Ovarian Cancer: A Novel and Potential Therapeutic Target

Authors: Xiaojie Feng, Xupeng Bai, Jie Ni, Valerie C. Wasinger, Julia Beretov, Ying Zhu, Peter Graham, Yong Li

Source: Frontiers in Oncology, Vol 9 (2019)

Subject Terms: ovarian cancer, chemoresistance, CHTOP, apoptosis, stemness, metastasis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fonc.2019.00557/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/4484cc1ccadd4c22be5947ef2f8979a2

The Fifth Domain of Beta 2 Glycoprotein I Protects from Natural IgM Mediated Cardiac Ischaemia Reperfusion Injury.

Authors: Peng Zhang, James C Weaver, Gang Chen, Julia Beretov, Tatsuya Atsumi, Miao Qi, Ravinay Bhindi, Jian C Qi, Michele C Madigan, Bill Giannakopoulos, Steven A Krilis

Source: PLoS ONE, Vol 11, Iss 3, p e0152681 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4816326?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/9abaf199061541dab78dd488bcc47df2

Proteomic Analysis of Urine to Identify Breast Cancer Biomarker Candidates Using a Label-Free LC-MS/MS Approach.

Authors: Julia Beretov, Valerie C Wasinger, Ewan K A Millar, Peter Schwartz, Peter H Graham, Yong Li

Source: PLoS ONE, Vol 10, Iss 11, p e0141876 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4636393?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/969b0aee0bcd41d1a5e73a8a24806eab

In vitro and in vivo prostate cancer metastasis and chemoresistance can be modulated by expression of either CD44 or CD147.

Authors: Jingli Hao, Michele C Madigan, Aparajita Khatri, Carl A Power, Tzong-Tyng Hung, Julia Beretov, Lei Chang, Weiwei Xiao, Paul J Cozzi, Peter H Graham, John H Kearsley, Yong Li

Source: PLoS ONE, Vol 7, Iss 8, p e40716 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3411712?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/4d2a63119ea24d06957d0bacb41535df

Anti-MUC1 monoclonal antibody (C595) and docetaxel markedly reduce tumor burden and ascites, and prolong survival in an in vivo ovarian cancer model.

Authors: Li Wang, Hongmin Chen, Mohammad H Pourgholami, Julia Beretov, Jingli Hao, Hongtu Chao, Alan C Perkins, John H Kearsley, Yong Li

Source: PLoS ONE, Vol 6, Iss 9, p e24405 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3170300?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/347bd2e49d014941885779c10d1cbad2