Genomic characterisation of invasive Neisseria meningitidis in Spain (2011/12-2022/23): Expansion of clonal complex 213 and the potential threat to 4CMenB vaccine strain coverage.

Authors: Josep Roca-Grande, Alba Mir-Cros, Carmen Muñoz-Almagro, Mayli Lung, Alba Bellés-Bellés, Jordi Càmara, Emilia Cercenado, M. A. Galán-Ladero, Andrea Martín-Nalda, Albert Moreno-Mingorance, Daniel Navarro de la Cruz, M. Ángeles Orellana, Begoña Palop, Amaresh Pérez-Argüello, Guillem Puigsech-Boixeda, M. Dolores Quesada, Alba Rivera, Ana Rodriguez-Fernandez, Enrique Ruiz de Gopegui, Carolina Sarvisé, Aleix Soler-Garcia, Belén Viñado, Nieves Larrosa, Juan José González-López

Source: Emerging Microbes and Infections (2025)

Subject Terms: Neisseria meningitidis, whole genome sequencing, genomic epidemiology, cc213, gMATS, antimicrobial susceptibility, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/4ff3aba1fd234d00a980ec97099bd077

Reemergence of pertussis: Strategies and challenges in its control in Spain

Authors: Fernando Moraga-Llop, María Garcés-Sánchez, Juan José González-López

Source: Anales de Pediatría (English Edition), Vol 101, Iss 4, Pp 227-229 (2024)

Subject Terms: Pediatrics, RJ1-570

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2341287924002266; https://doaj.org/toc/2341-2879

Access URL: https://doaj.org/article/fb1d1abc0aba4d3a8ab2c9be7f29a91c

Burden of bacterial antimicrobial resistance among hospitalised patients in Spain: findings from three nationwide prospective studiesResearch in context

Authors: Germán Peñalva, Rafael Cantón, María Teresa Pérez-Rodríguez, Juan José González-López, Jesús Rodríguez-Baño, Ester del Barrio-Tofiño, Cristina Kirkegaard-Biosca, Isabel Sánchez-Romero, Andrea Gutiérrez-Villanueva, Teresa Marrodán-Ciordia, José Manuel Guerra-Laso, Cristóbal del Rosario-Quintana, Laura Suárez-Hormiga, Jordi Cámara, Mireia Puig-Asensio, Eva Heredero, María Antonia Sepúlveda, Juan Carlos Rodríguez-Díaz, Esperanza Merino, Emilia Cercenado, Sofia de la Villa, María Siller, Francisco Arnaiz, Cristina Seral, José Antonio Lepe, José Miguel Cisneros, José Ramón Paño-Pardo

Source: The Lancet Regional Health. Europe, Vol 51, Iss , Pp 101220- (2025)

Subject Terms: Antimicrobial resistance, Infections, Burden, Hospital, Spain, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666776225000122; https://doaj.org/toc/2666-7762

Access URL: https://doaj.org/article/3fdef49020c94ae49c1aa095f9743a07

Synergistic impact of innate immunity hyper-activation and endothelial dysfunction on the magnitude of organ failure in the infection-sepsis continuum

Authors: Amanda de la Fuente, Jaime López-Sánchez, Luis Mario Vaquero-Roncero, María Merino García, María Elisa Sánchez Barrado, Miguel Vicente Sánchez-Hernández, Nadia Garcia-Mateo, Jesús Rico-Feijoo, Luis Muñoz-Bellvís, Rafael González de Castro, Ana P. Tedim, Alicia Ortega, Omar Abdel-lah Fernández, Alejandro Suárez-de-la-Rica, Emilio Maseda, Ignacio Trejo González, Geovanna Liszeth García Carrera, José Miguel Marcos-Vidal, Juan Manuel Nieto Arranz, Luis Chiscano-Camón, Ricard Ferrer, Juan Carlos Ruiz-Rodríguez, Juan José González-López, José Alberto Vila Fernández, Regina Prieto Carballo, Raul Lopez-Izquierdo, Sonsoles Garrosa, Beatriz Barón, Carmen Esteban-Velasco, César Aldecoa, Jesús F. Bermejo-Martin

Source: International Journal of Infectious Diseases, Vol 146, Iss , Pp 107142- (2024)

Subject Terms: Biomarkers, Diagnosis, Infection, Severity, Synergy, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1201971224002133; https://doaj.org/toc/1201-9712

Access URL: https://doaj.org/article/d193e3546e644fe7a3b40e3197e19adb

Correction: Kirkegaard-Biosca et al. Cefiderocol for the Treatment of Infections by VIM-Type-Producing Gram-Negative Bacteria. Antibiotics 2024, 13, 874

Authors: Cristina Kirkegaard-Biosca, Ester del Barrio-Tofiño, Miguel Villamarín, Nieves Larrosa, David Campany, Juan José González-López, Ricard Ferrer, Belén Viñado, Laura Doménech, Julia Sellarès-Nadal, Laura Escolà-Vergé, Nuria Fernández-Hidalgo, Ibai Los-Arcos

Source: Antibiotics, Vol 14, Iss 1, p 4 (2024)

Subject Terms: n/a, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2079-6382/14/1/4; https://doaj.org/toc/2079-6382

Access URL: https://doaj.org/article/863047714fd24cd7ab746e44b9efd411

Ciprofloxacin for the Treatment of Infections Caused by Carbapenemase-Producing Gram-Negative Bacteria

Authors: Pablo Rubiñan, Belén Viñado, Nuria Fernández-Hidalgo, Nieves Larrosa, Abiu Sempere, David Campany, Dolors Rodríguez-Pardo, Juan José González-López, Xavier Nuvials, Ester del Barrio-Tofiño, Laura Escolà-Vergé, Ibai Los-Arcos

Source: Antibiotics, Vol 13, Iss 12, p 1138 (2024)

Subject Terms: fluoroquinolones, OXA, VIM, multidrug-resistant, carbapenem-resistant, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2079-6382/13/12/1138; https://doaj.org/toc/2079-6382

Access URL: https://doaj.org/article/c8120718c6694f27a6c1234f5bc9fa1d

Pertussis Outbreak During 2023 in Gipuzkoa, North Spain

Authors: José María Marimón, Milagrosa Montes, Nahikari Vizuete, Lorea Alvarez Guerrico, Adrian Hugo Aginagalde, Alba Mir-Cros, Juan José González-López, Diego Vicente

Source: Vaccines, Vol 12, Iss 10, p 1192 (2024)

Subject Terms: Bordetella pertussis, vaccination, outbreak, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/12/10/1192; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/a09690e9f3704314860b9bf87884938c

Cefiderocol for the Treatment of Infections by VIM-Type-Producing Gram-Negative Bacteria

Authors: Cristina Kirkegaard-Biosca, Ester del Barrio-Tofiño, Miguel Villamarín, Nieves Larrosa, David Campany, Juan José González-López, Ricard Ferrer, Belén Viñado, Laura Doménech, Julia Sellarès-Nadal, Laura Escolà-Vergé, Nuria Fernández-Hidalgo, Ibai Los-Arcos

Source: Antibiotics, Vol 13, Iss 9, p 874 (2024)

Subject Terms: metallo-β-lactamase, siderophore, multidrug resistant, extremely drug resistant, carbapenemase, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2079-6382/13/9/874; https://doaj.org/toc/2079-6382

Access URL: https://doaj.org/article/be6da14aa44945c1a5940975089e7a03

Clinical, microbiological, and molecular characterization of pediatric invasive infections by Streptococcus pyogenes in Spain in a context of global outbreak

Authors: Eva Ramírez de Arellano, Jesús Saavedra-Lozano, Pilar Villalón, Ana Jové-Blanco, David Grandioso, Jared Sotelo, Anna Gamell, Juan José González-López, Eloísa Cervantes, María José Gónzalez, Victoria Rello-Saltor, Cristina Esteva, Francisco Sanz-Santaeufemia, Genoveva Yagüe, Ángela Manzanares, Patricia Brañas, Enrique Ruiz de Gopegui, Jaime Carrasco-Colom, Federico García, Emilia Cercenado, Isabel Mellado, Elena del Castillo, María Pérez-Vazquez, Jesús Oteo-Iglesias, Cristina Calvo

Source: mSphere, Vol 9, Iss 3 (2024)

Subject Terms: Streptococcus pyogenes, children, invasive disease, outbreak, GAS, M1UK, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5042

Access URL: https://doaj.org/article/69c392608b224a1b89e00ee75e3e80ae

The prognostic impact of SIGLEC5-induced impairment of CD8+ T cell activation in sepsisResearch in context

Authors: Roberto Lozano-Rodríguez, José Avendaño-Ortíz, Karla Montalbán-Hernández, Juan Carlos Ruiz-Rodríguez, Ricardo Ferrer, Alejandro Martín-Quirós, Charbel Maroun-Eid, Juan José González-López, Anna Fàbrega, Verónica Terrón-Arcos, María Gutiérrez-Fernández, Elisa Alonso-López, Carolina Cubillos-Zapata, María Fernández-Velasco, Rebeca Pérez de Diego, Pablo Pelegrin, Carlos García-Palenciano, Francisco J. Cueto, Carlos del Fresno, Eduardo López-Collazo

Source: EBioMedicine, Vol 97, Iss , Pp 104841- (2023)

Subject Terms: Sepsis, Immune checkpoint, SIGLEC5, T-cell exhaustion, Biomarker, HIF1α, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396423004073; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/3b43bccf46634fe7872802feee4227c8

Corrigendum: CARB-ES-19 multicenter study of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli from all Spanish provinces reveals interregional spread of high-risk clones such as ST307/OXA-48 and ST512/KPC-3

Authors: Javier E. Cañada-García, Zaira Moure, Pedro J. Sola-Campoy, Mercedes Delgado-Valverde, María E. Cano, Desirèe Gijón, Mónica González, Irene Gracia-Ahufinger, Nieves Larrosa, Xavier Mulet, Cristina Pitart, Alba Rivera, Germán Bou, Jorge Calvo, Rafael Cantón, Juan José González-López, Luis Martínez-Martínez, Ferran Navarro, Antonio Oliver, Zaira R. Palacios-Baena, Álvaro Pascual, Guillermo Ruiz-Carrascoso, Jordi Vila, Belén Aracil, María Pérez-Vázquez, Jesús Oteo-Iglesias, The GEMARA/GEIRAS-SEIMC/REIPI CARB-ES-19 Study Group

Source: Frontiers in Microbiology, Vol 14 (2023)

Subject Terms: CARB-ES-19 study, carbapenemases, whole genome sequencing, Klebsiella pneumoniae, high-risk clones, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2023.1331657/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/d8e8ea1460df44a8a786a8ba94b74b9a

Catastrophic Streptococcus pyogenes Disease: A Personalized Approach Based on Phenotypes and Treatable Traits

Authors: Juan Carlos Ruiz-Rodríguez, Luis Chiscano-Camón, Carolina Maldonado, Adolf Ruiz-Sanmartin, Laura Martin, Ivan Bajaña, Juliana Bastidas, Rocio Lopez-Martinez, Clara Franco-Jarava, Juan José González-López, Vicent Ribas, Nieves Larrosa, Jordi Riera, Xavier Nuvials-Casals, Ricard Ferrer

Source: Antibiotics, Vol 13, Iss 2, p 187 (2024)

Subject Terms: severe sepsis, septic shock, multiorgan dysfunction, precision medicine, hemoadsorption, S. pyogenes, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2079-6382/13/2/187; https://doaj.org/toc/2079-6382

Access URL: https://doaj.org/article/8a245370080b423b979281d694857ec0

Pertactin-Deficient Bordetella pertussis with Unusual Mechanism of Pertactin Disruption, Spain, 1986–2018

Authors: Alba Mir-Cros, Albert Moreno-Mingorance, M. Teresa Martín-Gómez, Raquel Abad, Iván Bloise, Magda Campins, Alejandro González-Praetorius, M. Nieves Gutiérrez, Héctor Martín-González, Carmen Muñoz-Almagro, M. Ángeles Orellana, Manuela de Pablos, Josep Roca-Grande, Carlos Rodrigo, M. Elena Rodríguez, Sonia Uriona, M. José Vidal, Tomàs Pumarola, M. Nieves Larrosa, Juan José González-López

Source: Emerging Infectious Diseases, Vol 28, Iss 5, Pp 967-976 (2022)

Subject Terms: Bordetella pertussis, whooping cough, pertussis vaccine, phylogenetic evolution, virulence factors, bacteria, Medicine, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://wwwnc.cdc.gov/eid/article/28/5/21-1958_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059

Access URL: https://doaj.org/article/b888152680d3447e9c9ecc4c3d7ced7d

Use of Biomarkers to Improve 28-Day Mortality Stratification in Patients with Sepsis and SOFA ≤ 6

Authors: Jaume Baldirà, Juan Carlos Ruiz-Rodríguez, Adolfo Ruiz-Sanmartin, Luis Chiscano, Alejandro Cortes, Diego Ángeles Sistac, Roser Ferrer-Costa, Inma Comas, Yolanda Villena, Maria Nieves Larrosa, Juan José González-López, Ricard Ferrer

Source: Biomedicines, Vol 11, Iss 8, p 2149 (2023)

Subject Terms: sepsis biomarkers, mortality, MR-proADM, SOFA score, lactate, molecular diagnosis, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/11/8/2149; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/080de973d0834f8c9c863f98371f9503

CARB-ES-19 Multicenter Study of Carbapenemase-Producing Klebsiella pneumoniae and Escherichia coli From All Spanish Provinces Reveals Interregional Spread of High-Risk Clones Such as ST307/OXA-48 and ST512/KPC-3

Authors: Javier E. Cañada-García, Zaira Moure, Pedro J. Sola-Campoy, Mercedes Delgado-Valverde, María E. Cano, Desirèe Gijón, Mónica González, Irene Gracia-Ahufinger, Nieves Larrosa, Xavier Mulet, Cristina Pitart, Alba Rivera, Germán Bou, Jorge Calvo, Rafael Cantón, Juan José González-López, Luis Martínez-Martínez, Ferran Navarro, Antonio Oliver, Zaira R. Palacios-Baena, Álvaro Pascual, Guillermo Ruiz-Carrascoso, Jordi Vila, Belén Aracil, María Pérez-Vázquez, Jesús Oteo-Iglesias, the GEMARA/GEIRAS-SEIMC/REIPI CARB-ES-19 Study Group, Mariela Martínez Ramírez, Pilar Zamarrón, Miriam Albert Hernández, M. Pilar Ortega Lafont, Emilia Cercenado, Cristobal del Rosario and Jose Luis Perez Arellano, María Lecuona, Luis López-Urrutia Lorente, José Leiva and José Luis del Pozo, Salvador Giner and Juan Frasquet, Lidia Garcia Agudo and Soledad Illescas, Pedro de la Iglesia, Rosario Sánchez Benito, Eugenio Garduño, Ma Isabel Fernández Natal and Marta Arias, Marta Lamata Subero, Mar Olga Pérez Moreno, Ana Isabel López-Calleja, Luis Torres Sopena, José Manuel Azcona, Alba Belles, Mercè García González, Miriam Valverde Troya and Begoña Palop, Fernando García Garrote, Jose Luis Barrios Andrés, Leyre López Soria, Adelina Gimeno, Susana Sabater, Ester Clapés Sanchez, Jennifer Villa, Nuria Iglesias Nuñez, Rafael Sánchez Arroyo, Inmaculada García García, Susana Hernando, Cristina Seral, Javier Castillo, Eva Riquelme Bravo, Caridad Sainz de Baranda, Oscar Esparcia Rodríguez, Jorge Gaitán, María Huertas, M.a José Rodríguez Escudero, Carmen Aldea, Nerea Sanchez, Antonio Casabella Pernas, Ma Dolores Quesada, Maria Pilar Chocarro, Francisco Javier Ramos, Carmina Martí Sala, Laura Mora, Encarnación Clavijo, Natalia Chueca, Federico García, José Gutierrez Fernández, Juan Manuel Sánchez Hospital de Jérez, Fátima Galán Sánchez, Carmen Liébana, Carolina Roldán, Ma Isabel Cabeza, José María Saavedra, Ma Teresa Cabezas Fernández, Lucía Martínez Lamas, Sonia Rey Cao, Ma Isabel Paz Vidal, Raquel Elisa Rodríguez Tarazona, Amparo Coira Nieto, Ma Luisa Pérez del Molino Bernal, María Gomáriz Díaz, Matxalen Vidal-García, Jose Luis Díaz de Tuesta, Moises García Bravo, Almudena Tinajas, Andrés Canut Blasco, Ma Luz Albina Cordón Rodriguez, Nieves Gonzalo Jiménez, Genoveva Yagüe Guirao, Fe Tubau Quintano, Carmen Aspiroz, Nuria Prim, Jesús Rodríguez-Baño

Source: Frontiers in Microbiology, Vol 13 (2022)

Subject Terms: CARB-ES-19 study, carbapenemases, whole genome sequencing, Klebsiella pneumoniae, high-risk clones, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2022.918362/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/c831203d7c1340e4ad2a0ecc469ac6d7

Biomarkers and clinical scores to aid the identification of disease severity and intensive care requirement following activation of an in-hospital sepsis code

Authors: Jaume Baldirà, Juan Carlos Ruiz-Rodríguez, Darius Cameron Wilson, Adolf Ruiz-Sanmartin, Alejandro Cortes, Luis Chiscano, Roser Ferrer-Costa, Inma Comas, Nieves Larrosa, Anna Fàbrega, Juan José González-López, Ricard Ferrer

Source: Annals of Intensive Care, Vol 10, Iss 1, Pp 1-11 (2020)

Subject Terms: Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/2110-5820

Access URL: https://doaj.org/article/14ef772f11ec43b3a737545da5192b81

Population dynamics and antigenic drift of Bordetella pertussis following whole cell vaccine replacement, Barcelona, Spain, 1986–2015

Authors: Alba Mir-Cros, Albert Moreno-Mingorance, M. Teresa Martín-Gómez, Gema Codina, Thais Cornejo-Sánchez, Mireia Rajadell, Diego Van Esso, Carlos Rodrigo, Magda Campins, Mireia Jané, Tomàs Pumarola, Anna Fàbrega, Juan José González-López

Source: Emerging Microbes and Infections, Vol 8, Iss 1, Pp 1711-1720 (2019)

Subject Terms: Whooping cough, PFGE, MLVA, antigenic variants, pertussis vaccine, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/45f7a6d7cebd49e4bc1ddb84a2b6ebde

Emergence of Bordetella holmesii as a Causative Agent of Whooping Cough, Barcelona, Spain

Authors: Alba Mir-Cros, Gema Codina, M. Teresa Martín-Gómez, Anna Fàbrega, Xavier Martínez, Mireia Jané, Diego Van Esso, Thais Cornejo, Carlos Rodrigo, Magda Campins, Tomàs Pumarola, Juan José González-López

Source: Emerging Infectious Diseases, Vol 23, Iss 11, Pp 1856-1859 (2017)

Subject Terms: whooping cough, Bordetella holmesii, Bordetella pertussis, pertussis vaccine, Barcelona, Spain, Medicine, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://wwwnc.cdc.gov/eid/article/23/11/17-0960_article; https://doaj.org/toc/1080-6040; https://doaj.org/toc/1080-6059

Access URL: https://doaj.org/article/4ab394210c874fb0ba5e5023b7905b7c

Genomic analysis of the meningococcal ST-4821 complex-Western clade, potential sexual transmission and predicted antibiotic susceptibility and vaccine coverage.

Authors: Jay Lucidarme, Bingqing Zhu, Li Xu, Xilian Bai, Yuan Gao, Juan José González-López, Robert Mulhall, Kevin J Scott, Andrew Smith, Paola Stefanelli, Bianca Stenmark, Paul Torpiano, Georgina Tzanakaki, Ray Borrow, Zhujun Shao

Source: PLoS ONE, Vol 15, Iss 12, p e0243426 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/7fdc16acd1d74624bc34f6c4b7b35293

Ultrasensitive Label-Free Detection of Unamplified Multidrug-Resistance Bacteria Genes with a Bimodal Waveguide Interferometric Biosensor

Authors: Jesús Maldonado, Ana Belén González-Guerrero, Adrián Fernández-Gavela, Juan José González-López, Laura M. Lechuga

Source: Diagnostics, Vol 10, Iss 10, p 845 (2020)

Subject Terms: nanophotonic biosensor, multidrug-resistance, Escherichia coli, bimodal waveguide interferometer, NDM, CTX-M, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2075-4418/10/10/845; https://doaj.org/toc/2075-4418

Access URL: https://doaj.org/article/6a1614313fe94de5a88d4ee6dc358c7d