Inflammatory macrophages reprogram to immunosuppression by reducing mitochondrial translation

Authors: Marlies Cortés, Agnese Brischetto, M. C. Martinez-Campanario, Chiara Ninfali, Verónica Domínguez, Sara Fernández, Raquel Celis, Anna Esteve-Codina, Juan J. Lozano, Julia Sidorova, Gloria Garrabou, Anna-Maria Siegert, Carlos Enrich, Belén Pintado, Manuel Morales-Ruiz, Pedro Castro, Juan D. Cañete, Antonio Postigo

Source: Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/655d9568306f4699a3a035f4045e67b7

Transcriptomics and translatomics identify a robust inflammatory gene signature in brain endothelial cells after ischemic stroke

Authors: Maria Arbaizar-Rovirosa, Mattia Gallizioli, Juan J. Lozano, Julia Sidorova, Jordi Pedragosa, Sara Figuerola, Nerea Chaparro-Cabanillas, Patricia Boya, Mariona Graupera, Marc Claret, Xabier Urra, Anna M. Planas

Source: Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)

Subject Terms: Ischemic stroke, Microvasculature, RiboTag, Fluorescence-activated cell sorting, Inflammation, Lipids, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/2dad4d4b24154fa2b3afec406eac02c6

The EMT factor ZEB1 paradoxically inhibits EMT in BRAF-mutant carcinomas

Authors: Ester Sánchez-Tilló, Leire Pedrosa, Ingrid Vila, Yongxu Chen, Balázs Győrffy, Lidia Sánchez-Moral, Laura Siles, Juan J. Lozano, Anna Esteve-Codina, Douglas S. Darling, Miriam Cuatrecasas, Antoni Castells, Joan Maurel, Antonio Postigo

Source: JCI Insight, Vol 8, Iss 20 (2023)

Subject Terms: Gastroenterology, Oncology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/4f52e0f35736437f9fa276db1cd3e738

Neddylation tunes peripheral blood mononuclear cells immune response in COVID-19 patients

Authors: Marina Serrano-Maciá, Sofia Lachiondo-Ortega, Paula Iruzubieta, Naroa Goikoetxea-Usandizaga, Alexandre Bosch, Leire Egia-Mendikute, Borja Jiménez-Lasheras, Mikel Azkargorta, Félix Elortza, Diana Martinez-Redondo, Begoña Castro, Juan J. Lozano, Ruben Nogueiras, Juan Irure-Ventura, Javier Crespo, Asís Palazón, María Carmen Fariñas, Teresa C. Delgado, Marcos López-Hoyos, Maria L. Martínez-Chantar

Source: Cell Death Discovery, Vol 8, Iss 1, Pp 1-11 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2058-7716

Access URL: https://doaj.org/article/c37889da4c8f470fb3ab7cab0a924429

Treatment With Simvastatin and Rifaximin Restores the Plasma Metabolomic Profile in Patients With Decompensated Cirrhosis

Authors: Elisa Pose, Elsa Solà, Juan J. Lozano, Adrià Juanola, Julia Sidorova, Giacomo Zaccherini, Koos deWit, Frank Uschner, Marta Tonon, Konstantin Kazankov, Cesar Jiménez, Daniela Campion, Laura Napoleone, Ann T. Ma, Marta Carol, Manuel Morales‐Ruiz, Carlo Alessandria, Ulrich Beuers, Paolo Caraceni, Claire Francoz, François Durand, Rajeshwar P. Mookerjee, Jonel Trebicka, Victor Vargas, Salvatore Piano, Hugh Watson, Juan G. Abraldes, Patrick S. Kamath, Mark M. Davis, Pere Ginès, for the investigators of the LIVERHOPE Consortium

Source: Hepatology Communications, Vol 6, Iss 5, Pp 1100-1112 (2022)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/2471-254X

Access URL: https://doaj.org/article/ef91c857b6d7462f9f2e68c608047196

Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases

Authors: Nurdan Guldiken, Josepmaria Argemi, Berivan Gurbuz, Stephen R. Atkinson, Martin Oliverius, Petr Fila, Karim Hamesch, Tony Bruns, Joaquín Cabezas, Juan J. Lozano, Jelena Mann, Sheng Cao, Philippe Mathurin, Vijay H. Shah, Christian Trautwein, Mark R. Thursz, Ramon Bataller, Pavel Strnad

Source: BMC Medicine, Vol 19, Iss 1, Pp 1-12 (2021)

Subject Terms: End-stage liver disease, Cirrhosis, Alcoholic hepatitis, Transferrin, HNF4alpha, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/1275100d75664e55abccc68f1de7fd24

Author Correction: Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

Authors: Josepmaria Argemi, Maria U. Latasa, Stephen R. Atkinson, Ilya O. Blokhin, Veronica Massey, Joel P. Gue, Joaquin Cabezas, Juan J. Lozano, Derek Van Booven, Aaron Bell, Sheng Cao, Lawrence A. Vernetti, Juan P. Arab, Meritxell Ventura-Cots, Lia R. Edmunds, Constantino Fondevila, Peter Stärkel, Laurent Dubuquoy, Alexandre Louvet, Gemma Odena, Juan L. Gomez, Tomas Aragon, Jose Altamirano, Juan Caballeria, Michael J. Jurczak, D. Lansing Taylor, Carmen Berasain, Claes Wahlestedt, Satdarshan P. Monga, Marsha Y. Morgan, Pau Sancho-Bru, Philippe Mathurin, Shinji Furuya, Carolin Lackner, Ivan Rusyn, Vijay H. Shah, Mark R. Thursz, Jelena Mann, Matias A. Avila, Ramon Bataller

Source: Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/65a267dd546740ec9b7190c3e67982ab

Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

Authors: Josepmaria Argemi, Maria U. Latasa, Stephen R. Atkinson, Ilya O. Blokhin, Veronica Massey, Joel P. Gue, Joaquin Cabezas, Juan J. Lozano, Derek Van Booven, Aaron Bell, Sheng Cao, Lawrence A. Vernetti, Juan P. Arab, Meritxell Ventura-Cots, Lia R. Edmunds, Constantino Fondevila, Peter Stärkel, Laurent Dubuquoy, Alexandre Louvet, Gemma Odena, Juan L. Gomez, Tomas Aragon, Jose Altamirano, Juan Caballeria, Michael J. Jurczak, D. Lansing Taylor, Carmen Berasain, Claes Wahlestedt, Satdarshan P. Monga, Marsha Y. Morgan, Pau Sancho-Bru, Philippe Mathurin, Shinji Furuya, Carolin Lackner, Ivan Rusyn, Vijay H. Shah, Mark R. Thursz, Jelena Mann, Matias A. Avila, Ramon Bataller

Source: Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0fb71062dc154a909e1831b9bf41223d

Urine cell-based DNA methylation classifier for monitoring bladder cancer

Authors: Antoine G. van der Heijden, Lourdes Mengual, Mercedes Ingelmo-Torres, Juan J. Lozano, Cindy C. M. van Rijt-van de Westerlo, Montserrat Baixauli, Bogdan Geavlete, Cristian Moldoveanud, Cosmin Ene, Colin P. Dinney, Bogdan Czerniak, Jack A. Schalken, Lambertus A. L. M. Kiemeney, Maria J. Ribal, J. Alfred Witjes, Antonio Alcaraz

Source: Clinical Epigenetics, Vol 10, Iss 1, Pp 1-10 (2018)

Subject Terms: Cytology, Biomarkers, Bladder cancer, DNA methylation, Non-invasive diagnosis, Urine, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13148-018-0496-x; https://doaj.org/toc/1868-7075; https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/8651be5e88ee4c048d19e26012477337

Signal Integration and Transcriptional Regulation of the Inflammatory Response Mediated by the GM-/M-CSF Signaling Axis in Human Monocytes

Authors: Ramon M. Rodriguez, Beatriz Suarez-Alvarez, Jose L. Lavín, Alex M. Ascensión, Monika Gonzalez, Juan J. Lozano, Aroa B. Raneros, Paula D. Bulnes, Jose R. Vidal-Castiñeira, Covadonga Huidobro, Cristina Martin-Martin, Ana B. Sanz, Marta Ruiz-Ortega, Amaya Puig-Kröger, Angel L. Corbí, Marcos J. Araúzo-Bravo, Ana M. Aransay, Carlos Lopez-Larrea

Source: Cell Reports, Vol 29, Iss 4, Pp 860-872.e5 (2019)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124719312239; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/69b31ac581ed459390e887cfe1dc0c24

Transient hyperglycemia during liver transplantation does not affect the early graft function

Authors: Annabel Blasi, M.D., Ph.D., Joan Beltran, Nuria Martin, Graciela Martinez-Pallí, Juan J. Lozano, Jaume Balust, Abigail Torrents, Pilar Taura

Source: Annals of Hepatology, Vol 14, Iss 5, Pp 675-687 (2015)

Subject Terms: End-stage liver disease, Glucose control, Graft outcome, Liver donor, Glucose metabolism, Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1665268119307628; https://doaj.org/toc/1665-2681

Access URL: https://doaj.org/article/a2899e37c41e4da1bc7d7656c60167f3

Aged lipid‐laden microglia display impaired responses to stroke

Authors: Maria Arbaizar‐Rovirosa, Jordi Pedragosa, Juan J Lozano, Carme Casal, Albert Pol, Mattia Gallizioli, Anna M Planas

Source: EMBO Molecular Medicine, Vol 15, Iss 2, Pp 1-21 (2022)

Subject Terms: brain, immunometabolism, ischemia, lipid droplets, microglia, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/f503b251ee6345c69a8d6dabdc97ae1b

Multi-omic modelling of inflammatory bowel disease with regularized canonical correlation analysis.

Authors: Lluís Revilla, Aida Mayorgas, Ana M Corraliza, Maria C Masamunt, Amira Metwaly, Dirk Haller, Eva Tristán, Anna Carrasco, Maria Esteve, Julian Panés, Elena Ricart, Juan J Lozano, Azucena Salas

Source: PLoS ONE, Vol 16, Iss 2, p e0246367 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/50243484fe1242f99311ebb83345da34