Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes

Authors: Richardson Jill C, Virley David J, Babin Anna, Bate Simon T, Joyce Flora, Perren Marion J, Seymour Zoe, Culbert Ainsley A, Ashmeade Tracey, Vidgeon-Hart Martin P, Pugh Perdita L, Upton Neil, Sunter David

Source: Journal of Neuroinflammation, Vol 4, Iss 1, p 8 (2007)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.jneuroinflammation.com/content/4/1/8; https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/ae681b8d7d8249279dee2c56557753b6

Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes.

Authors: Pugh, Perdita L., Vidgeon-Hart, Martin P., Ashmeade, Tracey, Culbert, Ainsley A., Seymour, Zoe, Perren, Marion J., Joyce, Flora, Bate, Simon T., Babin, Anna, Virley, David J., Richardson, Jill C., Upton, Neil, Sunter, David

Source: Journal of Neuroinflammation; 2007, Vol. 4, p1-16, 16p, 10 Diagrams, 1 Chart

Subject Terms: ANTIOXIDANTS, ALZHEIMER'S disease, NEUROTRANSMITTERS, NORADRENALINE, AMYLOID beta-protein precursor, MESSENGER RNA