Initial therapeutic evidence of a borosilicate bioactive glass (BSG) and Fe3O4 magnetic nanoparticle scaffold on implant-associated Staphylococcal aureus bone infection

Authors: Ying Jin, Hang Liu, Lei Chu, Jin Yang, Xiuyang Li, Hang Zhou, Haitao Jiang, Lei Shi, Jason Weeks, Joshua Rainbolt, Changjiang Yang, Thomas Xue, Haobo Pan, Zhongliang Deng, Chao Xie, Xu Cui, Youliang Ren

Source: Bioactive Materials, Vol 40, Iss , Pp 148-167 (2024)

Subject Terms: Osteomyelitis, Staphylococcus aureus, Biofilm, Borosilicate bioactive glass, Magnetic nanoparticles, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X24002068; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/17b33c820b634900ac3290a183da1481

Evidence of bisphosphonate-conjugated sitafloxacin eradication of established methicillin-resistant S. aureus infection with osseointegration in murine models of implant-associated osteomyelitis

Authors: Youliang Ren, Jason Weeks, Thomas Xue, Joshua Rainbolt, Karen L. de Mesy Bentley, Ye Shu, Yuting Liu, Elysia Masters, Philip Cherian, Charles E. McKenna, Jeffrey Neighbors, Frank H. Ebetino, Edward M. Schwarz, Shuting Sun, Chao Xie

Source: Bone Research, Vol 11, Iss 1, Pp 1-13 (2023)

Subject Terms: Biology (General), QH301-705.5, Physiology, QP1-981

File Description: electronic resource

Relation: https://doaj.org/toc/2095-6231

Access URL: https://doaj.org/article/96b573a5a803436d94a93195b6f70cb2

A semi-automated cell tracking protocol for quantitative analyses of neutrophil swarming to sterile and S. aureus contaminated bone implants in a mouse femur model.

Authors: Sashank Lekkala, Youliang Ren, Jason Weeks, Kevin Lee, Allie Jia Hui Tay, Bei Liu, Thomas Xue, Joshua Rainbolt, Chao Xie, Edward M Schwarz, Shu-Chi A Yeh

Source: PLoS ONE, Vol 19, Iss 6, p e0296140 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/f6f06ec7a3c44185971dea8a5b03ae10

Efficacy of Bisphosphonate-Conjugated Sitafloxacin in a Murine Model of S. aureus Osteomyelitis: Evidence of 'Target & Release' Kinetics and Killing of Bacteria Within Canaliculi

Authors: Youliang Ren, Thomas Xue, Joshua Rainbolt, Karen L. de Mesy Bentley, Chad A. Galloway, Yuting Liu, Philip Cherian, Jeffrey Neighbors, Marloes I. Hofstee, Frank H. Ebetino, Thomas Fintan Moriarty, Shuting Sun, Edward M. Schwarz, Chao Xie

Source: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)

Subject Terms: osteomyelitis, Staphylococcus aureus, transmission electron microscopy, antibiotic, bisphosphonate, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2022.910970/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/bce85e9c2bad40a79c4e87db39e8c0b8