Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils

Authors: Joseph R. Patterson, Joseph Kochmanski, Anna C. Stoll, Michael Kubik, Christopher J. Kemp, Megan F. Duffy, Kajene Thompson, Jacob W. Howe, Allyson Cole-Strauss, Nathan C. Kuhn, Kathryn M. Miller, Seth Nelson, Christopher U. Onyekpe, John S. Beck, Scott E. Counts, Alison I. Bernstein, Kathy Steece-Collier, Kelvin C. Luk, Caryl E. Sortwell

Source: npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-17 (2024)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2373-8057

Access URL: https://doaj.org/article/8bde4016617e4debb09532f2fc4a2cc0

Parkinson’s disease-associated, sex-specific changes in DNA methylation at PARK7 (DJ-1), SLC17A6 (VGLUT2), PTPRN2 (IA-2β), and NR4A2 (NURR1) in cortical neurons

Authors: Joseph Kochmanski, Nathan C. Kuhn, Alison I. Bernstein

Source: npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-13 (2022)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2373-8057

Access URL: https://doaj.org/article/4cdfcdf39e54442ab2a0599f220e9af5

Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits

Authors: Aysegul O. Gezer, Joseph Kochmanski, Sarah E. VanOeveren, Allyson Cole-Strauss, Christopher J. Kemp, Joseph R. Patterson, Kathryn M. Miller, Nathan C. Kuhn, Danielle E. Herman, Alyssa McIntire, Jack W. Lipton, Kelvin C. Luk, Sheila M. Fleming, Caryl E. Sortwell, Alison I. Bernstein

Source: Neurobiology of Disease, Vol 141, Iss , Pp 104947- (2020)

Subject Terms: Parkinson's, Pesticide, Synuclein, Neurotoxicity, Neuroinflammation, Sex differences, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996120302229; https://doaj.org/toc/1095-953X

Access URL: https://doaj.org/article/212f253653d444c5bfd9ea221a1eac9e

Age-related epigenome-wide DNA methylation and hydroxymethylation in longitudinal mouse blood

Authors: Joseph Kochmanski, Elizabeth H. Marchlewicz, Raymond G. Cavalcante, Maureen A. Sartor, Dana C. Dolinoy

Source: Epigenetics, Vol 13, Iss 7, Pp 779-792 (2018)

Subject Terms: epigenetics, dna methylation, dna hydroxymethylation, aging, mouse, blood, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1559-2294; https://doaj.org/toc/1559-2308

Access URL: https://doaj.org/article/9642916dec5b440e9564d066a8981c71

A Novel Application of Mixed Effects Models for Reconciling Base-Pair Resolution 5-Methylcytosine and 5-Hydroxymethylcytosine Data in Neuroepigenetics

Authors: Joseph Kochmanski, Candace Savonen, Alison I. Bernstein

Source: Frontiers in Genetics, Vol 10 (2019)

Subject Terms: neuroepigenetics, mixed effects model for repeated measures, 5-methylcytosine, 5-hydroxymethylcytosine, bioinformatics, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fgene.2019.00801/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/ea340d7f8e5e46ba871a6494931c28bd