CD69 expression on regulatory T cells protects from immune damage after myocardial infarction

Authors: Rafael Blanco-Domínguez, Hortensia de la Fuente, Cristina Rodríguez, Laura Martín-Aguado, Raquel Sánchez-Díaz, Rosa Jiménez-Alejandre, Iker Rodríguez-Arabaolaza, Andrea Curtabbi, Marcos M. García-Guimaraes, Alberto Vera, Fernando Rivero, Javier Cuesta, Luis J. Jiménez-Borreguero, Alberto Cecconi, Albert Duran-Cambra, Manel Taurón, Judith Alonso, Héctor Bueno, María Villalba-Orero, Jose Antonio Enríquez, Simon C. Robson, Fernando Alfonso, Francisco Sánchez-Madrid, José Martínez-González, Pilar Martín

Source: The Journal of Clinical Investigation, Vol 132, Iss 21 (2022)

Subject Terms: Cardiology, Immunology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/83c8ea564fce4635b87c375e73188959

Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue

Authors: Alba Gonzalez-Franquesa, Pau Gama-Perez, Marta Kulis, Karolina Szczepanowska, Norma Dahdah, Sonia Moreno-Gomez, Ana Latorre-Pellicer, Rebeca Fernández-Ruiz, Antoni Aguilar-Mogas, Anne Hoffman, Erika Monelli, Sara Samino, Joan Miró-Blanch, Gregor Oemer, Xavier Duran, Estrella Sanchez-Rebordelo, Marc Schneeberger, Merce Obach, Joel Montane, Giancarlo Castellano, Vicente Chapaprieta, Wenfei Sun, Lourdes Navarro, Ignacio Prieto, Carlos Castaño, Anna Novials, Ramon Gomis, Maria Monsalve, Marc Claret, Mariona Graupera, Guadalupe Soria, Christian Wolfrum, Joan Vendrell, Sonia Fernández-Veledo, Jose Antonio Enríquez, Angel Carracedo, José Carlos Perales, Rubén Nogueiras, Laura Herrero, Aleksandra Trifunovic, Markus A. Keller, Oscar Yanes, Marta Sales-Pardo, Roger Guimerà, Matthias Blüher, José Ignacio Martín-Subero, Pablo M. Garcia-Roves

Source: Redox Biology, Vol 54, Iss , Pp 102353- (2022)

Subject Terms: Obesity, Metabolic plasticity, Visceral adipose tissue, Mitochondrial dysfunction, Exercise, Caloric restriction, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231722001252; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/ad594c8df2c8447b85a354bfb7fa6b81

The Value of Mouse Models of Rare Diseases: A Spanish Experience

Authors: Silvia Murillo-Cuesta, Rafael Artuch, Fernando Asensio, Pedro de la Villa, Mara Dierssen, Jose Antonio Enríquez, Cristina Fillat, Stéphane Fourcade, Borja Ibáñez, Lluis Montoliu, Eduardo Oliver, Aurora Pujol, Eduardo Salido, Mario Vallejo, Isabel Varela-Nieto

Source: Frontiers in Genetics, Vol 11 (2020)

Subject Terms: orphan diseases, animal models, preclinical research, novel therapies, ethics, transparency, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fgene.2020.583932/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/428bc5c42dc84d1ea2cf9b8a26ecb5e0

MicroRNA‐661 modulates redox and metabolic homeostasis in colon cancer

Authors: Marta Gómez de Cedrón, Rebeca Acín Pérez, Ruth Sánchez‐Martínez, Susana Molina, Jesús Herranz, Jaime Feliu, Guillermo Reglero, Jose Antonio Enríquez, Ana Ramírez de Molina

Source: Molecular Oncology, Vol 11, Iss 12, Pp 1768-1787 (2017)

Subject Terms: bioenergetics, colon cancer, metabolomics, miR, oxidative stress, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/cdc8d33a94fa4c84965e6e9dc952d09d

MKK6 controls T3-mediated browning of white adipose tissue

Authors: Nuria Matesanz, Edgar Bernardo, Rebeca Acín-Pérez, Elisa Manieri, Sonia Pérez-Sieira, Lourdes Hernández-Cosido, Valle Montalvo-Romeral, Alfonso Mora, Elena Rodríguez, Luis Leiva-Vega, Ana Victoria Lechuga-Vieco, Jesús Ruiz-Cabello, Jorge L. Torres, Maria Crespo-Ruiz, Francisco Centeno, Clara V. Álvarez, Miguel Marcos, Jose Antonio Enríquez, Ruben Nogueiras, Guadalupe Sabio

Source: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/2aee8a2191dc416bb7efc458ac892fc6

Mitochondria in endothelial cells: Sensors and integrators of environmental cues

Authors: Sergio Caja, Jose Antonio Enríquez

Source: Redox Biology, Vol 12, Iss , Pp 821-827 (2017)

Subject Terms: Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231717301106; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/ddc950cac31f4b21b9a9325af4ce2637

Absence of MCJ/DnaJC15 promotes brown adipose tissue thermogenesis

Authors: Beatriz Cicuéndez, Alfonso Mora, Juan Antonio López, Andrea Curtabbi, Javier Pérez-García, Begoña Porteiro, Daniel Jimenez-Blasco, Pedro Latorre-Muro, Paula Vo, Madison Jerome, Beatriz Gómez-Santos, Rafael Romero-Becerra, Magdalena Leiva, Elena Rodríguez, Marta León, Luis Leiva-Vega, Noemi Gómez-Lado, Jorge L. Torres, Lourdes Hernández-Cosido, Pablo Aguiar, Miguel Marcos, Martin Jastroch, Andreas Daiber, Patricia Aspichueta, Juan Pedro Bolaños, Jessica B. Spinelli, Pere Puigserver, José Antonio Enriquez, Jesús Vázquez, Cintia Folgueira, Guadalupe Sabio

Source: Nature Communications, Vol 16, Iss 1, Pp 1-16 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/680f12e6ff5245c9830f5d0e0a4a7050

Shaping current European mitochondrial haplogroup frequency in response to infection: the case of SARS-CoV-2 severity

Authors: José Luis Cabrera-Alarcon, Raquel Cruz, Marina Rosa-Moreno, Ana Latorre-Pellicer, Silvia Diz de Almeida, Scourge Cohort Group, José A. Riancho, Augusto Rojas-Martinez, Carlos Flores, Pablo Lapunzina, Fátima Sánchez-Cabo, Ángel Carracedo, José Antonio Enriquez

Source: Communications Biology, Vol 8, Iss 1, Pp 1-12 (2025)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/f678158976b24325b6137402fb7a0804

TET3 regulates terminal cell differentiation at the metabolic level

Authors: Isabel Mulet, Carmen Grueso-Cortina, Mireia Cortés-Cano, Daniela Gerovska, Guangming Wu, Stefania Alexandra Iakab, Daniel Jimenez-Blasco, Andrea Curtabbi, Pablo Hernansanz-Agustín, Harmony Ketchum, Israel Manjarrés-Raza, F. Thomas Wunderlich, Juan Pedro Bolaños, Meelad M. Dawlaty, Carsten Hopf, José Antonio Enríquez, Marcos J. Araúzo-Bravo, Natalia Tapia

Source: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/bc646249624b4d23967654764f32eee6

Regulation of respiratory complex I assembly by FMN cofactor targeting

Authors: Andrea Curtabbi, Adela Guarás, José Luis Cabrera-Alarcón, Maribel Rivero, Enrique Calvo, Marina Rosa-Moreno, Jesús Vázquez, Milagros Medina, José Antonio Enríquez

Source: Redox Biology, Vol 69, Iss , Pp 103001- (2024)

Subject Terms: Respiratory complex I, FMN, OXPHOS, DPI, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231723004020; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/a71adee731ca4f05938fc739793e0634

Mitochondrial DNA impact on joint damaged process in a conplastic mouse model after being surgically induced with osteoarthritis

Authors: Morena Scotece, Ignacio Rego-Pérez, Ana Victoria Lechuga-Vieco, Alberto Centeno Cortés, María Concepción Jiménez-Gómez, Purificación Filgueira-Fernández, Carlos Vaamonde-García, José Antonio Enríquez, Francisco J. Blanco

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/b5574bd366dc4090abea5086ff794bf4

p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1.

Authors: Ayelén M Santamans, Valle Montalvo-Romeral, Alfonso Mora, Juan Antonio Lopez, Francisco González-Romero, Daniel Jimenez-Blasco, Elena Rodríguez, Aránzazu Pintor-Chocano, Cristina Casanueva-Benítez, Rebeca Acín-Pérez, Luis Leiva-Vega, Jordi Duran, Joan J Guinovart, Jesús Jiménez-Borreguero, José Antonio Enríquez, María Villlalba-Orero, Juan P Bolaños, Patricia Aspichueta, Jesús Vázquez, Bárbara González-Terán, Guadalupe Sabio

Source: PLoS Biology, Vol 19, Iss 11, p e3001447 (2021)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/c36e9e81543246be91c8817f25d367e5

The cristae modulator Optic atrophy 1 requires mitochondrial ATP synthase oligomers to safeguard mitochondrial function

Authors: Rubén Quintana-Cabrera, Charlotte Quirin, Christina Glytsou, Mauro Corrado, Andrea Urbani, Anna Pellattiero, Enrique Calvo, Jesús Vázquez, José Antonio Enríquez, Christoph Gerle, María Eugenia Soriano, Paolo Bernardi, Luca Scorrano

Source: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a66df5bbbc5c4ae5970022ce8e2ac008

Priming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts

Authors: Daniel Torralba, Francesc Baixauli, Carolina Villarroya-Beltri, Irene Fernández-Delgado, Ana Latorre-Pellicer, Rebeca Acín-Pérez, Noa B Martín-Cófreces, Ángel Luis Jaso-Tamame, Salvador Iborra, Inmaculada Jorge, Gloria González-Aseguinolaza, Johan Garaude, Miguel Vicente-Manzanares, José Antonio Enríquez, María Mittelbrunn, Francisco Sánchez-Madrid

Source: Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0eb2c72dba52481d83ba1541aba39d30

Role of Mitochondrial Complex IV in Age-Dependent Obesity

Authors: Ines Soro-Arnaiz, Qilong Oscar Yang Li, Mar Torres-Capelli, Florinda Meléndez-Rodríguez, Sónia Veiga, Koen Veys, David Sebastian, Ainara Elorza, Daniel Tello, Pablo Hernansanz-Agustín, Sara Cogliati, Jose Maria Moreno-Navarrete, Eduardo Balsa, Esther Fuertes, Eduardo Romanos, Antonio Martínez-Ruiz, Jose Antonio Enriquez, Jose Manuel Fernandez-Real, Antonio Zorzano, Katrien De Bock, Julián Aragonés

Source: Cell Reports, Vol 16, Iss 11, Pp 2991-3002 (2016)

Subject Terms: mitochondrial complex IV, mitochondrial dysfunction, COX5B, aging, white adipocytes, obesity, HIF-1, human adipose tissue, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124716311056; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/ec5bffb74faf4884a7b206fc053bc329

Generation of Reactive Oxygen Species by Mitochondria

Authors: Pablo Hernansanz-Agustín, José Antonio Enríquez

Source: Antioxidants, Vol 10, Iss 3, p 415 (2021)

Subject Terms: mitochondria, ROS, mechanism, signalling, disease, supercomplexes, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/10/3/415; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/d3762706fcd646c2b4f9f3ad74e4a467

p38α blocks brown adipose tissue thermogenesis through p38δ inhibition.

Authors: Nuria Matesanz, Ivana Nikolic, Magdalena Leiva, Marta Pulgarín-Alfaro, Ayelén M Santamans, Edgar Bernardo, Alfonso Mora, Leticia Herrera-Melle, Elena Rodríguez, Daniel Beiroa, Ainoa Caballero, Elena Martín-García, Rebeca Acín-Pérez, Lourdes Hernández-Cosido, Luis Leiva-Vega, Jorge L Torres, Francisco Centeno, Angel R Nebreda, José Antonio Enríquez, Rubén Nogueiras, Miguel Marcos, Guadalupe Sabio

Source: PLoS Biology, Vol 16, Iss 7, p e2004455 (2018)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/7b1012e9ad58499a8892f749da55d5de

ISG15 governs mitochondrial function in macrophages following vaccinia virus infection.

Authors: Sara Baldanta, Mercedes Fernández-Escobar, Rebeca Acín-Perez, Manuel Albert, Emilio Camafeita, Inmaculada Jorge, Jesús Vázquez, José Antonio Enríquez, Susana Guerra

Source: PLoS Pathogens, Vol 13, Iss 10, p e1006651 (2017)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/11243e29ade9435f95c9f10a3db0891c

CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart.

Authors: Melisa Gomez-Velazquez, Claudio Badia-Careaga, Ana Victoria Lechuga-Vieco, Rocio Nieto-Arellano, Juan J Tena, Isabel Rollan, Alba Alvarez, Carlos Torroja, Eva F Caceres, Anna R Roy, Niels Galjart, Paul Delgado-Olguin, Fatima Sanchez-Cabo, Jose Antonio Enriquez, Jose Luis Gomez-Skarmeta, Miguel Manzanares

Source: PLoS Genetics, Vol 13, Iss 8, p e1006985 (2017)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5591014?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/89938fe383824c28944e93f4a726cb88

ATP-Dependent Lon Protease Controls Tumor Bioenergetics by Reprogramming Mitochondrial Activity

Authors: Pedro M. Quirós, Yaiza Español, Rebeca Acín-Pérez, Francisco Rodríguez, Clea Bárcena, Kenta Watanabe, Enrique Calvo, Marta Loureiro, M. Soledad Fernández-García, Antonio Fueyo, Jesús Vázquez, José Antonio Enríquez, Carlos López-Otín

Source: Cell Reports, Vol 8, Iss 2, Pp 542-556 (2014)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124714004860; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/c628e3a772344fb6bec50e4f632d1921