A prospective cross-sectional study of tuberculosis in elderly Hispanics reveals that BCG vaccination at birth is protective whereas diabetes is not a risk factor.

Authors: Julia M Scordo, Génesis P Aguillón-Durán, Doris Ayala, Ana Paulina Quirino-Cerrillo, Eminé Rodríguez-Reyna, Francisco Mora-Guzmán, Jose A Caso, Eder Ledezma-Campos, Larry S Schlesinger, Jordi B Torrelles, Joanne Turner, Blanca I Restrepo

Source: PLoS ONE, Vol 16, Iss 7, p e0255194 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/03498bbd35c84731be4b317a9a08baf5

Evaluation of the tuberculosis culture color plate test for rapid detection of drug susceptible and drug-resistant Mycobacterium tuberculosis in a resource-limited setting, Addis Ababa, Ethiopia.

Authors: Biruk Mekonnen, Adane Mihret, Muluwork Getahun, Tsegaye Hailu, Sabeen Sidiki, Holden V Kelley, Julia M Scordo, W Garrett Hunt, Xueliang Pan, Joan-Miquel Balada-Llasat, Wondwossen Gebreyes, Carlton A Evans, Abraham Aseffa, Jordi B Torrelles, Shu-Hua Wang, Tamrat Abebe

Source: PLoS ONE, Vol 14, Iss 5, p e0215679 (2019)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/615a3be900ee425a8e21f673ae6e4547

Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (ABC) transporter Rv1747 to regulate mycobacterial growth.

Authors: Lisa N Glass, Ganduri Swapna, Sivagami Sundaram Chavadi, JoAnn M Tufariello, Kaixia Mi, Joshua E Drumm, TuKiet T Lam, Guofeng Zhu, Chenyang Zhan, Catherine Vilchéze, Jesus Arcos, Yong Chen, Lijun Bi, Simren Mehta, Steven A Porcelli, Steve C Almo, Syun-Ru Yeh, William R Jacobs, Jordi B Torrelles, John Chan

Source: PLoS Pathogens, Vol 13, Iss 7, p e1006515 (2017)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/6d48c6ed73d94b888c9e8814f3059ad9

Entrapment of H1N1 Influenza Virus Derived Conserved Peptides in PLGA Nanoparticles Enhances T Cell Response and Vaccine Efficacy in Pigs.

Authors: Jagadish Hiremath, Kyung-il Kang, Ming Xia, Mohamed Elaish, Basavaraj Binjawadagi, Kang Ouyang, Santosh Dhakal, Jesus Arcos, Jordi B Torrelles, X Jiang, Chang Won Lee, Gourapura J Renukaradhya

Source: PLoS ONE, Vol 11, Iss 4, p e0151922 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4836704?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/6a6a5185522c40718ad60dfb47cb2ca8

Characterization of clinical and environmental Mycobacterium avium spp. isolates and their interaction with human macrophages.

Authors: Evelyn Guirado, Jesus Arcos, Rose Knaup, Rebecca Reeder, Bret Betz, Cassie Cotton, Tejal Patel, Stacy Pfaller, Jordi B Torrelles, Larry S Schlesinger

Source: PLoS ONE, Vol 7, Iss 9, p e45411 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3446901?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/56c3ef9f48d74c4f86b426876a98bce4

Polyphosphate kinase 2: a novel determinant of stress responses and pathogenesis in Campylobacter jejuni.

Authors: Dharanesh Gangaiah, Zhe Liu, Jesús Arcos, Issmat I Kassem, Yasser Sanad, Jordi B Torrelles, Gireesh Rajashekara

Source: PLoS ONE, Vol 5, Iss 8, p e12142 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2923150?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/85b5e6c705a446c096977502eeb8d08d

Mitochondrial Transplantation Promotes Protective Effector and Memory CD4+ T Cell Response During Mycobacterium Tuberculosis Infection and Diminishes Exhaustion and Senescence in Elderly CD4+ T cells

Authors: Colwyn A. Headley, Shalini Gautam, Angelica Olmo‐Fontanez, Andreu Garcia‐Vilanova, Varun Dwivedi, Alyssa Schami, Susan Weintraub, Philip S. Tsao, Jordi B. Torrelles, Joanne Turner

Source: Advanced Science, Vol 11, Iss 36, Pp n/a-n/a (2024)

Subject Terms: CD4+ T Cells, cellular reprogramming, immune aging, immunometabolism, mitochondrial dysfunction, mitochondrial reprogramming, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/0dd086a82df94a179d0e656b797beb92

Extracellular Delivery of Functional Mitochondria Rescues the Dysfunction of CD4+ T Cells in Aging

Authors: Colwyn A. Headley, Shalini Gautam, Angelica Olmo‐Fontanez, Andreu Garcia‐Vilanova, Varun Dwivedi, Anwari Akhter, Alyssa Schami, Kevin Chiem, Russell Ault, Hao Zhang, Hong Cai, Alison Whigham, Jennifer Delgado, Amberlee Hicks, Philip S. Tsao, Jonathan Gelfond, Luis Martinez‐Sobrido, Yufeng Wang, Jordi B. Torrelles, Joanne Turner

Source: Advanced Science, Vol 11, Iss 5, Pp n/a-n/a (2024)

Subject Terms: adaptive immunity, aging immunology, CD4+ T cells, immunometabolism, mitochondrial dysfunction, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/155b08ee8fdd4021bcf7f433c2bfd1c0

Drug-resistant strains of Mycobacterium tuberculosis: cell envelope profiles and interactions with the host

Authors: Alyssa Schami, M. Nurul Islam, John T. Belisle, Jordi B. Torrelles

Source: Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)

Subject Terms: Mycobacterium tuberculosis, tuberculosis, drug resistance, cell envelope lipids, M.tb-host interactions, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2023.1274175/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/955ec4360fcd4a1b91e395dd115a0479

Collected Thoughts on Mycobacterial Lipoarabinomannan, a Cell Envelope Lipoglycan

Authors: Jordi B. Torrelles, Delphi Chatterjee

Source: Pathogens, Vol 12, Iss 11, p 1281 (2023)

Subject Terms: tuberculosis, Mycobacterium tuberculosis, lipoarabinomannan, lipoglycan, mycobacteria, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/12/11/1281; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/bbb454411ebe44db8449daad7c1a970b

Differential Role of Type 2 Diabetes as a Risk Factor for Tuberculosis in the Elderly versus Younger Adults

Authors: Blanca I. Restrepo, Julia M. Scordo, Génesis P. Aguillón-Durán, Doris Ayala, Ana Paulina Quirino-Cerrillo, Raúl Loera-Salazar, America Cruz-González, Jose A. Caso, Mateo Joya-Ayala, Esperanza M. García-Oropesa, Alejandra B. Salinas, Leonardo Martinez, Larry S. Schlesinger, Jordi B. Torrelles, Joanne Turner

Source: Pathogens, Vol 11, Iss 12, p 1551 (2022)

Subject Terms: tuberculosis, elderly, diabetes, insulin resistance, inflammation, hyperglycemia, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/11/12/1551; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/74721901dd4d42b0aa47347e5d75d3fe

GMP Manufacturing and IND-Enabling Studies of a Recombinant Hyperimmune Globulin Targeting SARS-CoV-2

Authors: Rena A. Mizrahi, Wendy Y. Lin, Ashley Gras, Ariel R. Niedecken, Ellen K. Wagner, Sheila M. Keating, Nikita Ikon, Vishal A. Manickam, Michael A. Asensio, Jackson Leong, Angelica V. Medina-Cucurella, Emily Benzie, Kyle P. Carter, Yao Chiang, Robert C. Edgar, Renee Leong, Yoong Wearn Lim, Jan Fredrik Simons, Matthew J. Spindler, Kacy Stadtmiller, Nicholas Wayham, Dirk Büscher, Jose Vicente Terencio, Clara Di Germanio, Steven M. Chamow, Charles Olson, Paula A. Pino, Jun-Gyu Park, Amberlee Hicks, Chengjin Ye, Andreu Garcia-Vilanova, Luis Martinez-Sobrido, Jordi B. Torrelles, David S. Johnson, Adam S. Adler

Source: Pathogens, Vol 11, Iss 7, p 806 (2022)

Subject Terms: recombinant hyperimmune, GMP manufacturing, SARS-CoV-2, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/11/7/806; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/30fbcf61da8b46ddab93ba7e247ee57f

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Intranasal Delivery of an Adjuvanted Modified Live Porcine Reproductive and Respiratory Syndrome Virus Vaccine Reduces ROS Production.

Authors: Basavaraj Binjawadagi, Varun Dwivedi, Cordelia Manickam, Jordi B. Torrelles, Gourapura J. Renukaradhya

Source: Viral Immunology; Dec2011, Vol. 24 Issue 6, p475-482, 8p

Drug resistant Mycobacterium tuberculosis strains have altered cell envelope hydrophobicity that influences infection outcomes in human macrophages

Authors: Alyssa Schami, M. Nurul Islam, Matthew Wall, Amberlee Hicks, Reagan Meredith, Barry Kreiswirth, Barun Mathema, John T. Belisle, Jordi B. Torrelles

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)

Subject Terms: Mycobacterium tuberculosis, Drug resistance, Cell envelope composition, Phthiocerol dimycocerosates, Phosphatidyl-myo-inositol mannosides, Tuberculosis, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/d87e04e1822447feb537f16d0b585693

Interaction between type 2 diabetes and past COVID-19 on active tuberculosis

Authors: Liz E. Calles-Cabanillas, Genesis P. Aguillón-Durán, Doris Ayala, José A. Caso, Miguel Garza, Mateo Joya-Ayala, America M. Cruz-Gonzalez, Raul Loera-Salazar, Ericka Prieto-Martinez, Javier E. Rodríguez-Herrera, Esperanza M. Garcia-Oropesa, John M. Thomas, Miryoung Lee, Jordi B. Torrelles, Blanca I. Restrepo

Source: BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-8 (2024)

Subject Terms: Tuberculosis, COVID-19, Type 2 diabetes, Mexico, Cross-sectional study, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/1ac05464ef9c42918874ee26808df8bd

Impact of the elderly lung mucosa on Mycobacterium tuberculosis transcriptional adaptation during infection of alveolar epithelial cells

Authors: Angélica M. Olmo-Fontánez, Anna Allué-Guardia, Andreu Garcia-Vilanova, Jeremy Glenn, Shu-Hua Wang, Robert E. Merritt, Larry S. Schlesinger, Joanne Turner, Yufeng Wang, Jordi B. Torrelles

Source: Microbiology Spectrum, Vol 12, Iss 12 (2024)

Subject Terms: Mycobacterium tuberculosis, aging, alveolar epithelial cells, alveolar lining fluid, transcriptomics, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/d9dc8dd0667840c8b32cd41e3681410b

Publisher Correction: Drug resistant Mycobacterium tuberculosis strains have altered cell envelope hydrophobicity that influences infection outcomes in human macrophages

Authors: Alyssa Schami, M. Nurul Islam, Matthew Wall, Amberlee Hicks, Reagan Meredith, Barry Kreiswirth, Barun Mathema, John T. Belisle, Jordi B. Torrelles

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-1 (2025)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/5aeb5f85bed74e8da71792d77e85a495

Inactivation of Mycobacterium tuberculosis mannosyltransferase pimB reduces the cell wall lipoarabinomannan and lipomannan content and increases the rate of bacterial-induced human macrophage cell death.

Authors: Jordi B Torrelles, Lucy E DesJardin, Jessica MacNeil, Thomas M Kaufman, Beth Kutzbach, Rose Knaup, Travis R McCarthy, Sudagar S Gurcha, Gurdyal S Besra, Steven Clegg, Larry S Schlesinger

Source: Glycobiology. Jul2009, Vol. 19 Issue 7, p743-743. 1p.

Subject Terms: *MYCOBACTERIAL diseases, *LUNG diseases, *DISEASES, *AIR pollution, *SMOKING

Tuberculosis and COVID-19 in the elderly: factors driving a higher burden of disease

Authors: Anna Allué-Guardia, Jordi B. Torrelles, Alex Sigal

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: SARS-CoV-2, Mycobacterium tuberculosis, COVID-19, TB, elderly, immunity, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1250198/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/2840172a9d3749db8212ea47ad3248aa