Progressive Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) from a Young Age Due to a Rare Genetic Disorder, Familial Partial Lipodystrophy: A Case Report and Review of the Literature

Authors: Elena Vorona, Ekaterina Sorkina, Jonel Trebicka

Source: Livers, Vol 4, Iss 4, Pp 688-695 (2024)

Subject Terms: metabolic dysfunction-associated steatotic liver disease (MASLD), diabetes mellitus, hypertriglyceridemia, familial partial lipodystrophy (FPL), LMNA, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2673-4389/4/4/47; https://doaj.org/toc/2673-4389

Access URL: https://doaj.org/article/7ff19c3d659841d3abaaf4bdc8a1d54c

Ultrasound‐Defined Sarcopenia Independently Predicts Acute Decompensation in Advanced Chronic Liver Disease

Authors: Juliana Gödiker, Lea Schwind, Torid Jacob, Nina Böhling, Sara Noemi Reinartz Groba, Markus Kimmann, Jörn Arne Meier, Kai‐Henrik Peiffer, Jonel Trebicka, Johannes Chang, Michael Praktiknjo

Source: Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 6, Pp 2792-2802 (2024)

Subject Terms: ACLF, acute decompensation, chronic liver disease, cirrhosis, malnutrition, portal hypertension, Diseases of the musculoskeletal system, RC925-935, Human anatomy, QM1-695

File Description: electronic resource

Relation: https://doaj.org/toc/2190-5991; https://doaj.org/toc/2190-6009

Access URL: https://doaj.org/article/f61211b4d4cc4d12bfbe3298530a6ddd

Quantification of alcohol intake in patients with steatotic liver disease and excessive alcohol intake

Authors: Emil Deleuran Hansen, Nikolaj Torp, Stine Johansen, Johanne Kragh Hansen, Marianne Lerbæk Bergmann, Camilla Dalby Hansen, Sönke Detlefsen, Peter Andersen, Ida Villesen, Katrine Bech, Katrine Thorhauge, Gitte Hedegaard Jensen, Katrine Prier Lindvig, Torben Hansen, Emmanuel A. Tsochatzis, Jonel Trebicka, Maja Thiele, Aleksander Krag, Mads Israelsen

Source: JHEP Reports, Vol 7, Iss 1, Pp 101200- (2025)

Subject Terms: alcohol use disorder, alcohol-related liver disease, cirrhosis, steatotic liver disease, biomarker, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924002040; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/837e27182d874b8bb754189954358a11

Severe CSF immune cell alterations in cryptococcal meningitis gradually resolve during antifungal therapy

Authors: Christine Dambietz, Michael Heming, Tobias J. Brix, Andreas Schulte-Mecklenbeck, Phil-Robin Tepasse, Catharina C. Gross, Jonel Trebicka, Heinz Wiendl, Gerd Meyer zu Hörste

Source: BMC Neurology, Vol 24, Iss 1, Pp 1-19 (2024)

Subject Terms: Fungal meningitis, Cryptococcus neoformans, HIV, Antifungal therapy, Intrathecal immunity, Flow cytometry, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2377

Access URL: https://doaj.org/article/33ec184b3ce34f3fa8e275347fc6142b

Impact of SARS-CoV-2 vaccination in patients with vascular liver diseases: Observations from a VALDIG multicenter study

Authors: Valeria Perez-Campuzano, Pierre-Emmanuel Rautou, Thomas Marjot, Michael Praktiknjo, Edilmar Alvarado-Tapias, Laura Turco, Luis Ibáñez-Samaniego, Carlos González-Alayón, Ángela Puente, Elba Llop, Macarena Simón-Talero, Carmen Álvarez-Navascués, Thomas Reiberger, Xavier Verhelst, Luis Tellez, Johanna Birte Bergmann, Lara Orts, Giuseppe Grassi, Anna Baiges, Payance Audrey, Jonel Trebicka, Candid Villanueva, Maria Cristina Morelli, Sam Murray, Georgina Meacham, Marc Luetgehetmann, Julian Schulze zur Wiesch, Juan-Carlos García-Pagán, Eleanor Barnes, Aurélie Plessier, Virginia Hernández-Gea

Source: JHEP Reports, Vol 6, Iss 12, Pp 101191- (2024)

Subject Terms: Vascular liver disease, COVID-19 vaccine, portal thrombosis, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924001952; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/856e9da0590e419eb52a0c8c7c221e7e

Palmitoylcarnitine impairs immunity in decompensated cirrhosis

Authors: Ingrid Wei Zhang, María Belén Sánchez-Rodríguez, Cristina López-Vicario, Mireia Casulleras, Marta Duran-Güell, Roger Flores-Costa, Ferran Aguilar, Michael Rothe, Paula Segalés, Carmen García-Ruiz, José C. Fernández-Checa, Jonel Trebicka, Vicente Arroyo, Joan Clària

Source: JHEP Reports, Vol 6, Iss 11, Pp 101187- (2024)

Subject Terms: Immune cells, Acute decompensation of cirrhosis, Acylcarnitines, Mitochondrial dysfunction, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924001915; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/78ae3b3c40b44e31b1e8fa153dd30e7a

Albumin reprograms the B cell transcriptional landscape and improves neutrophil antimicrobial function in patients with decompensated cirrhosis

Authors: Joan Clària, Ferran Aguilar, Juan-José Lozano, Laura Jiménez-Gracia, Juan C. Nieto, Berta Romero-Grimaldo, Xavi Marcos-Fa, Emma Giarracco, Emmanuel Weiss, Jonel Trebicka, Inmaculada Hernàndez, Javier Fernandez, Mireia Casulleras, Cristina López-Vicario, Sinan Muldur, Alex Hopke, Alexandru Vlagea, Ana M. Aransay, Domenica Marchese, Mauro Bernardi, Rajiv Jalan, Paolo Angeli, Giuliana Magri, Andrea Cerutti, Daniel Irimia, Holger Heyn, Vicente Arroyo, Richard Moreau

Source: JHEP Reports, Vol 6, Iss 11, Pp 101184- (2024)

Subject Terms: Multiorgan failure, Inflammation, Immunosuppression, Gene expression, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924001885; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/02a18a65ecb849b786c19610418eddc6

A robust clustering strategy for stratification unveils unique patient subgroups in acutely decompensated cirrhosis

Authors: Sara Palomino-Echeverria, Estefania Huergo, Asier Ortega-Legarreta, Eva M. Uson Raposo, Ferran Aguilar, Carlos de la Peña-Ramirez, Cristina López-Vicario, Carlo Alessandria, Wim Laleman, Alberto Queiroz Farias, Richard Moreau, Javier Fernandez, Vicente Arroyo, Paolo Caraceni, Vincenzo Lagani, Cristina Sánchez-Garrido, Joan Clària, Jesper Tegner, Jonel Trebicka, Narsis A. Kiani, Nuria Planell, Pierre-Emmanuel Rautou, David Gomez-Cabrero

Source: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)

Subject Terms: Stratification, Clustering, Complex diseases, Cirrhosis, ACLF, Patient heterogeneity, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/afc33b047ee34914a86a10e0483c2fdb

Comparative analysis of SEC61A1 mutant R236C in two patient-derived cellular platforms

Authors: Matthias Weiand, Vanessa Sandfort, Oksana Nadzemova, Robert Schierwagen, Jonel Trebicka, Bernhard Schlevogt, Iyad Kabar, Hartmut Schmidt, Andree Zibert

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/cedbb668342747488178467fcfa116d3

Imaging-based diagnosis of sarcopenia for transplant-free survival in primary sclerosing cholangitis

Authors: Pedram Keshoofi, Philipp Schindler, Florian Rennebaum, Friederike Cordes, Haluk Morgul, Moritz Wildgruber, Hauke S. Heinzow, Andreas Pascher, Hartmut H. Schmidt, Anna Hüsing-Kabar, Michael Praktiknjo, Jonel Trebicka, Leon Louis Seifert

Source: BMC Gastroenterology, Vol 24, Iss 1, Pp 1-11 (2024)

Subject Terms: Skeletal muscle index, Chronic liver disease, Cirrhosis, meld, Standard exception criteria, Body mass index, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1471-230X

Access URL: https://doaj.org/article/5d904cb42d524456aa6fbff3d7cb3343

Decompensated MASH-Cirrhosis Model by Acute and Toxic Effects of Phenobarbital

Authors: Nico Kraus, Frank Erhard Uschner, Magnus Moeslein, Robert Schierwagen, Wenyi Gu, Maximilian Joseph Brol, Eike Fürst, Inga Grünewald, Sophie Lotersztajn, Pierre-Emmanuel Rautou, Marta Duran-Güell, Roger Flores Costa, Joan Clària, Jonel Trebicka, Sabine Klein

Source: Cells, Vol 13, Iss 20, p 1707 (2024)

Subject Terms: metabolic dysfunction-associated steatohepatitis (MASH), carbon tetrachloride (CCl4), high-fat and high-cholesterol Western diet (WD), phenobarbital (PB), long-term (LT), short-term (ST), Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/13/20/1707; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/a6c4dc46329743e4a0b6a44027d7501d

Soluble urokinase plasminogen activator receptor levels predict survival in patients with portal hypertension undergoing TIPS

Authors: Sven H. Loosen, Fabian Benz, Raphael Mohr, Philipp A. Reuken, Theresa H. Wirtz, Lioba Junker, Christian Jansen, Carsten Meyer, Michael Praktiknjo, Alexander Wree, Johanna Reißing, Münevver Demir, Wenyi Gu, Mihael Vucur, Robert Schierwagen, Andreas Stallmach, Anselm Kunstein, Johannes Bode, Christian Trautwein, Frank Tacke, Tom Luedde, Tony Bruns, Jonel Trebicka, Christoph Roderburg

Source: JHEP Reports, Vol 6, Iss 5, Pp 101054- (2024)

Subject Terms: suPAR, TIPS, portal hypertension, survival, biomarker, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924000557; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/1c0266d113654c7496f7e96b4601da0f

Operating under pressure: Is there a place for preoperative TIPS?

Authors: Michael Praktiknjo, Jonel Trebicka

Source: JHEP Reports, Vol 6, Iss 4, Pp 101034- (2024)

Subject Terms: cirrhosis, acute on chronic liver failure, surgery, endoscopy, TIPS, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924000351; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/09a9a7ed64c14b7a971e7f36fa40b65d

Infections increase the risk of decompensation and death in patients with early alcohol-related liver disease

Authors: Stine Johansen, Simon Langkjær, Ditlev Nytoft Rasmussen, Mads Israelsen, Nikolaj Torp, Katrine Lindvig, Maria Kjærgaard, Johanne Kragh Hansen, Camilla Dalby Hansen, Katrine Thorhauge, Peter Andersen, Sönke Detlefsen, Helene Bæk Juel, Ulrik Stenz Justesen, Torben Hansen, Aleksander Krag, Maja Thiele, Ema Anastasiadou, Manimozhian Arumugam, Peer Bork, Jenny Presto, Hans Israelsen, Morten Karsdal, Cristina Legido-Quigley, Hans Olav Melberg, Jonel Trebicka, Mathias Mann, Jelle Matthijnssens

Source: JHEP Reports, Vol 6, Iss 4, Pp 101016- (2024)

Subject Terms: Alcoholic liver disease, Decompensation, Fibrosis, Cirrhosis, Prognosis, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S258955592400017X; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/0139fe8a16594c2aabc3b535edca94a1

SARS-CoV-2 Infection Enhances Humoral Immune Response in Vaccinated Liver Transplant Recipients

Authors: Jan Basri Adiprasito, Tobias Nowacki, Richard Vollenberg, Jörn Arne Meier, Florian Rennebaum, Tina Schomacher, Jonel Trebicka, Julia Fischer, Eva U. Lorentzen, Phil-Robin Tepasse

Source: Antibodies, Vol 13, Iss 3, p 78 (2024)

Subject Terms: liver transplantation, SARS-CoV-2 infection, vaccination, humoral immunity, surrogate virus neutralization test, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4468/13/3/78; https://doaj.org/toc/2073-4468

Access URL: https://doaj.org/article/fe0b8f15854644d5ae5e0421baec4c66

Evolution of spontaneous portosystemic shunts over time and following aetiological intervention in patients with cirrhosis

Authors: Judit Vidal-González, Javier Martínez, Akhilesh Mulay, Marta López, Anna Baiges, Ahmed Elmahdy, Katharina Lampichler, Geert Maleux, Johannes Chang, Marta Poncela, Gavin Low, Gabriele Ghigliazza, Alexander Zipprich, Carmen Picón, Rushabh Shah, Elba Llop, Anna Darnell, Martin H. Maurer, Lawrence Bonne, Enrique Ramón, Sergi Quiroga, Juan G. Abraldes, Aleksander Krag, Jonel Trebicka, Cristina Ripoll, Vincenzo La Mura, Puneeta Tandon, Rita García-Martínez, Michael Praktiknjo, Wim Laleman, Thomas Reiberger, Annalisa Berzigotti, Virginia Hernández-Gea, José Luis Calleja, Emmanuel A. Tsochatzis, Agustín Albillos, Macarena Simón-Talero, Joan Genescà

Source: JHEP Reports, Vol 6, Iss 2, Pp 100977- (2024)

Subject Terms: Collateral vessels, Portal hypertension, Advanced chronic liver disease, Computed tomography, Magnetic resonance imaging, Hepatitis C virus, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555923003087; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/8faadbedefe94f429b7c6d5c607f716d

Personalised human albumin in patients with cirrhosis and ascites: design and rationale for the ALB-TRIAL - a randomised clinical biomarker validation trial

Authors: Torben Hansen, Pere Ginès, Wim Laleman, Peer Bork, Vishal C Patel, Debbie Shawcross, Robert Schierwagen, Camila Alvarez-Silva, Florence Servant, Jonel Trebicka, Benjamin Lelouvier, Manimozhiyan Arumugam, Ed J Kuijper, Frank Erhard Uschner, Michael Praktiknjo, Mária Papp, Saeed Shoaie, Michael Kühn, Maja Thiele, Paolo Angeli, Joan Claria, Vicente Arroyo, Manolo Laiola, Benoit Quinquis, Sabine Klein, Minneke J Coenraad, François Fenaille, Debbie Lindsay Shawcross, Wenyi Gu, Adria Juanola, Elisa Pose, Aleksander Krag, Ivica Letunic, Alain Pruvost, Hervé M Blottière, Nathalie Galleron, Cristina López-Vicario, Peter V Treit, Matthias Mann, Jelle Matthijnssens, Mark J W Mcphail, Philipp E Geyer, Hans Olav Melberg, Stefanie Kandels, Cristina Sánchez-Garrido, Florence A Castelli, Christophe Junot, Lars Asphaug, Mads Israelsen, Helene Bæk Juel, Nikolaj Torp, Minneke Coenraad, Marko Korenjak, Ferran Aguilar-Parera, Patricia Sierra-Casas, Anna Bosch-Comas, David Tornai, Boglarka Balogh, Katrine Holtz Thorhauge, Casper Sahl Poulsen, Thea Van Rossum, Suguru Nishijima, Marisa I Keller, Diënty H M Hazenbrink, Sylvain Dechaumet, Sebastian D Burz, Emeline Chu-Van, Etienne Thévenot, Florian A Rosenberger, Sebastian Van Blerk, Amirouche Ouzerdine, Alain Roulet, Jean-Louis-Marie Insonere, Céline Serres, Mathieu Almeida, Florence Thirion, Camille Champion, Chaima Ezzine, Célia Chamignon, Nicolas Lapaque, Mamadou Gabou Thiam, Lore Van Espen, Quinten R Ducarmon, Annelotte GC Broekhoven, Susan Fischer, Romy Zwittink, Itziar De Lecuona, Giulio Rosati, Celia Fuentes-Chust, Arben Merkoçi, Massimo Urban, José Alfonso Marrugo-Ramirez, Ameli Schwalber, Lindsey Ann Edwards, Victoria Tatiana Kronsten, David Moyes, Azadeh Harzandi, Jordi Gratacós-Ginès, Martina Pérez-Guasch, Miriam Pellón, Bryan Contreras, Max Brol, Manfred Fobker, Renata Antonina Feuerborn

Source: BMJ Open, Vol 14, Iss 2 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/14/2/e079309.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/289f12a27d2047adb5cb758cb2809703

Hepatobiliary manifestations in patients with ulcerative colitis: a retrospective analysis

Authors: Katharina Stratmann, Songül Aydolmus, Wenyi Gu, Dominik Heling, Ulrich Spengler, Birgit Terjung, Christian P. Strassburg, Richard Vollenberg, Irina Blumenstein, Jonel Trebicka

Source: Frontiers in Medicine, Vol 10 (2024)

Subject Terms: inflammatory bowel disease, ulcerative colitis, hepatobiliary disorder, liver function test (LFT), risk factor, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2023.1273797/full; https://doaj.org/toc/2296-858X

Access URL: https://doaj.org/article/af2fdedffa7a4c9aa3f913a8cf7921c1

The rationale and study design of two phase II trials examining the effects of BI 685509, a soluble guanylyl cyclase activator, on clinically significant portal hypertension in patients with compensated cirrhosis

Authors: Thomas Reiberger, Annalisa Berzigotti, Jonel Trebicka, Judith Ertle, Isabella Gashaw, Ros Swallow, Andrea Tomisser

Source: Trials, Vol 24, Iss 1, Pp 1-17 (2023)

Subject Terms: Portal hypertension, Cirrhosis, Alcohol-related liver disease, Hepatitis B virus, Hepatitis C virus, Non-alcoholic steatohepatitis, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/7ac232f531224101967542a04c0648e8

Circulating levels of endotrophin and cross-linked type III collagen reflect liver fibrosis in people with HIV

Authors: Leona Dold, Mette J. Nielsen, Michael Praktiknjo, Carolynne Schwarze-Zander, Christoph Boesecke, Jan-Christian Wasmuth, Jenny Bischoff, Jürgen Kurt Rockstroh, Morten A. Karsdal, Ulrich Spengler, Jonel Trebicka, Christian P. Strassburg, Diana J. Leeming, Bettina Langhans

Source: BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-9 (2023)

Subject Terms: PC3X, PRO-C5, PRO-C6, HIV, Liver fibrosis, Hepatic steatosis, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/a44fd9ba1d1f4da09ed1aa2b27340010