A Practical Guide to Teaching with Proteopedia

Authors: Castro, Claudia (ORCID 0000-0002-8428-2484), Johnson, R. Jeremy (ORCID 0000-0003-2694-3915), Kieffer, Bruno (ORCID 0000-0002-2033-4679), Means, John A., Taylor, Ann (ORCID 0000-0002-9594-8501), Telford, Jason, Thompson, Lynmarie K., Sussman, Joel L. (ORCID 0000-0003-0306-3878), Prilusky, Jaime (ORCID 0000-0002-7019-0191), Theis, Karsten (ORCID 0000-0003-2697-6143)

Source: Biochemistry and Molecular Biology Education. Sep-Oct 2021 49(5):707-719.

Peer Reviewed: Y

Page Count: 13

Descriptors: Science Instruction, Open Educational Resources, Molecular Biology, Science Activities

Transition metal cation inhibition of Mycobacterium tuberculosis esterase RV0045C

Authors: Bowles, Isobel E., Pool, Emily H., Lancaster, Benjamin S., Lawson, Emily K., Savas, Christopher P., Kartje, Zach J., Severinac, Luke, Cho, David H., Macbeth, Mark R., Johnson, R. Jeremy, Hoops, Geoffrey C.

Source: Protein science. 30(8):1554-1565

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123672483.0x000001&indx=1&recIds=ETOCvdc_100123672483.0x000001

Shifting Mycobacterial Serine Hydrolase Activity Visualized Using Multi-Layer In-Gel Activity Assays.

Authors: Goss, Allison L., Shudick, Renee E., Johnson, R. Jeremy

Source: Molecules; Jul2024, Vol. 29 Issue 14, p3386, 21p

Subject Terms: MYCOBACTERIUM tuberculosis, ENERGY harvesting, HYDROLASES, SUBSTRATES (Materials science), BIOCHEMICAL substrates

A dynamic loop provides dual control over the catalytic and membrane binding activity of a bacterial serine hydrolase

Authors: Smith, Mackenzie A., Phillips, Whitney K., Rabin, Perry L., Johnson, R. Jeremy

Source: In BBA - Proteins and Proteomics September 2018 1866(9):925-932

Fluorogenic structure activity library pinpoints molecular variations in substrate specificity of structurally homologous esterases

Authors: White, Alex, Koelper, Andrew, Russell, Arielle, Larsen, Erik M., Kim, Charles, Lavis, Luke D., Hoops, Geoffrey C., Johnson, R. Jeremy

Source: In Journal of Biological Chemistry September 2018 293(36):13851-13862

Role of a conserved family of serine hydrolases in ethanol toxicity

Authors: Leaman, Megan, Barton, Jennifer, Johnson, R. Jeremy

Source: FASEB journal. 36

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196446756.0x000001&indx=1&recIds=ETOCvdc_100196446756.0x000001

Arsenic-Based Life: An Active Learning Assignment for Teaching Scientific Discourse

Authors: Johnson, R. Jeremy

Source: Biochemistry and Molecular Biology Education. Jan-Feb 2017 45(1):40-45.

Peer Reviewed: Y

Page Count: 6

Descriptors: Active Learning, Assignments, Academic Discourse, Persuasive Discourse, Biochemistry, Undergraduate Students, College Science, Science Instruction

A conserved but structurally divergent loop in acyl protein thioesterase 1 regulates its catalytic activity, ligand binding, and folded stability.

Authors: Harris, William Trey, Altieri, Isabelle, Gieck, Isabella, Johnson, R. Jeremy

Source: Proteins; Jun2024, Vol. 92 Issue 6, p693-704, 12p

Implementation of a Collaborative Series of Classroom-Based Undergraduate Research Experiences Spanning Chemical Biology, Biochemistry, and Neurobiology

Authors: Kowalski, Jennifer R., Hoops, Geoffrey C., Johnson, R. Jeremy

Source: CBE - Life Sciences Education. Dec 2016 15(4).

Peer Reviewed: Y

Page Count: 17

Sponsoring Agency: National Institutes of Health (DHHS)
National Science Foundation (NSF)

Descriptors: Undergraduate Students, Class Activities, Student Research, Program Implementation, Teacher Collaboration, Student Experience, Biochemistry, Neurology, Research Projects, Curriculum Design, Curriculum Implementation, Course Descriptions, Student Attitudes, Retention (Psychology), Productivity, Barriers, Teacher Researchers, Science Process Skills, Statistical Analysis

Geographic Terms: Indiana (Indianapolis)

Abstract 1634 Distinct structural regions controlling the quaternary structure of a thermophilic esterase

Authors: Snook, Kate, Johnson, R. Jeremy

Source: In Journal of Biological Chemistry March 2024 300(3) Supplement

Abstract 1512 Quenching of dynamic shifts in the tryptophan fluorescence of an acyl protein thioesterase

Authors: Marcinek, Makenna, Johnson, R. Jeremy

Source: In Journal of Biological Chemistry March 2024 300(3) Supplement

Abstract 1297 Combined rational and combinatorial refinement of the substrate specificity and enzyme reactivity of a biocatalytic esterase

Authors: Johnson, R. Jeremy, Chezem, Cade, Kersey, Jessica, Hoops, Geoffrey

Source: In Journal of Biological Chemistry March 2024 300(3) Supplement

Abstract 1513 Identifying serine hydrolase activity in E. coli utilizing gene knockout strains

Authors: Kluszynski, Isabel, Thuma, Katherine, Johnson, R. Jeremy

Source: In Journal of Biological Chemistry March 2024 300(3) Supplement

Abstract 1511 Screening for serine hydrolase activity in E. coli against fluorogenic ester substrates

Authors: Thuma, Katherine, Kluszynski, Isabel, Johnson, R. Jeremy

Source: In Journal of Biological Chemistry March 2024 300(3) Supplement

The unusual substrate specificity of a virulence associated serine hydrolase from the highly toxic bacterium, Francisella tularensis

Authors: Farberg, Alexander M., Hart, Whitney K., Johnson, R. Jeremy

Source: In Biochemistry and Biophysics Reports September 2016 7:415-422

Comprehensive substrate specificity map of the mycobacterial serine hydrolase, LipN

Authors: Johnson, R. Jeremy, Schemenauer, Daniel, Pool, Emily, Hoops, Geoffrey

Source: FASEB journal. 35

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100123857475.0x000001&indx=1&recIds=ETOCvdc_100123857475.0x000001

A Sensitive and Robust Enzyme Kinetic Experiment Using Microplates and Fluorogenic Ester Substrates

Authors: Johnson, R. Jeremy, Hoops, Geoffrey C., Savas, Christopher J.

Source: Journal of Chemical Education. Feb 2015 92(2):385-388.

Peer Reviewed: Y

Page Count: 4

Sponsoring Agency: National Science Foundation

Descriptors: Science Instruction, Science Experiments, College Science, Undergraduate Study, Biochemistry, Kinetics, Spectroscopy, Light, Science Laboratories, Laboratory Experiments, Molecular Structure, Inquiry, Teaching Methods

Rapid and Adaptable Measurement of Protein Thermal Stability by Differential Scanning Fluorimetry: Updating a Common Biochemical Laboratory Experiment

Authors: Johnson, R. Jeremy, Savas, Christopher J., Kartje, Zachary

Source: Journal of Chemical Education. Jul 2014 91(7):1077-1080.

Peer Reviewed: Y

Page Count: 4

Descriptors: Biochemistry, Science Experiments, Laboratory Experiments, Science Activities, Undergraduate Students, College Science, Science Instruction

Ester-prodrugs of ethambutol control its antibacterial activity and provide rapid screening for mycobacterial hydrolase activity

Authors: Larsen, Erik M., Stephens, Dominique C., Clarke, Nathan H., Johnson, R. Jeremy

Source: Bioorganic & medicinal chemistry letters. 27(19):4544-4547

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100062689710.0x000001&indx=1&recIds=ETOCvdc_100062689710.0x000001

Teaching Foundational Topics and Scientific Skills in Biochemistry within the Conceptual Framework of HIV Protease

Authors: Johnson, R. Jeremy

Source: Biochemistry and Molecular Biology Education. Jul-Aug 2014 42(4):299-304.

Peer Reviewed: Y

Page Count: 6

Descriptors: Science Instruction, Biochemistry, Acquired Immunodeficiency Syndrome (AIDS), Communicable Diseases, Thermodynamics, Scientific Concepts, Science Process Skills, Computer Software, College Science, Undergraduate Students