Platelet integrin αIIbβ3 plays a key role in a venous thrombogenesis mouse model

Authors: Brian D. Adair, Conroy O. Field, José L. Alonso, Jian-Ping Xiong, Shi-Xian Deng, Hyun Sook Ahn, Eivgeni Mashin, Clary B. Clish, Johannes van Agthoven, Mark Yeager, Youzhong Guo, David A. Tess, Donald W. Landry, Mortimer Poncz, M. Amin Arnaout

Source: Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/5cb4e38292ca4761ba710d35e201c213

FLI1 and GATA1 govern TLN1 transcription: new insights into FLI1-related platelet disorders

Authors: Elisa Gabinaud, Laurent Hannouche, Mathilde Veneziano-Broccia, Johannes Van Agthoven, Justine Suffit, Julien Maurizio, Delphine Potier, Dominique Payet-Bornet, Delphine Bastelica, Elisa Andersen, Manal Ibrahim-Kosta, Timothée Bigot, Céline Falaise, Anne Vincenot, Pierre-Emmanuel Morange, Paul Saultier, Marie-Christine Alessi, Marjorie Poggi, Hemostasis Unit of Lille

Source: Haematologica, Vol 999, Iss 1 (2025)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/11886; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/fb37a3426d9242be9772d67047ce838b

Structure-guided design of pure orthosteric inhibitors of αIIbβ3 that prevent thrombosis but preserve hemostasis

Authors: Brian D. Adair, José L. Alonso, Johannes van Agthoven, Vincent Hayes, Hyun Sook Ahn, I-Shing Yu, Shu-Wha Lin, Jian-Ping Xiong, Mortimer Poncz, M. Amin Arnaout

Source: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/42565adb3ba2424890108c840e099336