MEF2A suppresses stress responses that trigger DDX41-dependent IFN production

Authors: Julian R. Smith, Jack W. Dowling, Matthew I. McFadden, Andrew Karp, Johannes Schwerk, Joshua J. Woodward, Ram Savan, Adriana Forero

Source: Cell Reports, Vol 42, Iss 8, Pp 112805- (2023)

Subject Terms: CP: Immunology, CP: Molecular biology, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124723008161; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/7cf0df17f19f4405a7343152e5294087

Type I Interferon Signaling Controls Gammaherpesvirus Latency In Vivo

Authors: Johannes Schwerk, Lucas Kemper, Kendra A. Bussey, Stefan Lienenklaus, Siegfried Weiss, Luka Čičin-Šain, Andrea Kröger, Ulrich Kalinke, Christopher M. Collins, Samuel H. Speck, Martin Messerle, Dagmar Wirth, Melanie M. Brinkmann, Hansjörg Hauser, Mario Köster

Source: Pathogens, Vol 11, Iss 12, p 1554 (2022)

Subject Terms: murine gammaherpesvirus 68, latency, chronic infection, type I interferon, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/11/12/1554; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/2db1caf9db6a4ebcb475422ae96a09da

Endomembrane targeting of human OAS1 p46 augments antiviral activity

Authors: Frank W Soveg, Johannes Schwerk, Nandan S Gokhale, Karen Cerosaletti, Julian R Smith, Erola Pairo-Castineira, Alison M Kell, Adriana Forero, Shivam A Zaver, Katharina Esser-Nobis, Justin A Roby, Tien-Ying Hsiang, Snehal Ozarkar, Jonathan M Clingan, Eileen T McAnarney, Amy EL Stone, Uma Malhotra, Cate Speake, Joseph Perez, Chiraag Balu, Eric J Allenspach, Jennifer L Hyde, Vineet D Menachery, Saumendra N Sarkar, Joshua J Woodward, Daniel B Stetson, John Kenneth Baillie, Jane H Buckner, Michael Gale Jr, Ram Savan

Source: eLife, Vol 10 (2021)

Subject Terms: innate immunity, interferon stimulated genes, RNA virus, COVID-19, SARS-CoV-2, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/71047; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/3265b04191644b45bacaf4c20c760cca

Flavivirus Nonstructural Protein NS5 Dysregulates HSP90 to Broadly Inhibit JAK/STAT Signaling

Authors: Justin A. Roby, Katharina Esser-Nobis, Elyse C. Dewey-Verstelle, Marian R. Fairgrieve, Johannes Schwerk, Amy Y. Lu, Frank W. Soveg, Emily A. Hemann, Lauren D. Hatfield, Brian C. Keller, Alexander Shapiro, Adriana Forero, Jennifer E. Stencel-Baerenwald, Ram Savan, Michael Gale

Source: Cells, Vol 9, Iss 4, p 899 (2020)

Subject Terms: flavivirus, JAK/STAT, cytokine, West Nile virus, Zika virus, HSP90, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/4/899; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/7543d266fff34f83bec7f5bdfb8814df

Multi‐layered stochasticity and paracrine signal propagation shape the type‐I interferon response

Authors: Ulfert Rand, Melanie Rinas, Johannes Schwerk, Gesa Nöhren, Melanie Linnes, Andrea Kröger, Michael Flossdorf, Kristóf Kály‐Kullai, Hansjörg Hauser, Thomas Höfer, Mario Köster

Source: Molecular Systems Biology, Vol 8, Iss 1, Pp 1-13 (2012)

Subject Terms: bacterial artificial chromosomes, gene expression, interferon regulatory factor‐7, live‐cell microscopy, multi‐scale modelling, Biology (General), QH301-705.5, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1744-4292

Access URL: https://doaj.org/article/7f837d2b0b1f40dcac2982f38342f341

Reversible silencing of cytomegalovirus genomes by type I interferon governs virus latency.

Authors: Franziska Dağ, Lars Dölken, Julia Holzki, Anja Drabig, Adrien Weingärtner, Johannes Schwerk, Stefan Lienenklaus, Ianina Conte, Robert Geffers, Colin Davenport, Ulfert Rand, Mario Köster, Siegfried Weiß, Barbara Adler, Dagmar Wirth, Martin Messerle, Hansjörg Hauser, Luka Cičin-Šain

Source: PLoS Pathogens, Vol 10, Iss 2, p e1003962 (2014)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003962&type=printable; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/095f735c42a44447901e4efb355df8b6

Generation of mouse small intestinal epithelial cell lines that allow the analysis of specific innate immune functions.

Authors: Johannes Schwerk, Mario Köster, Hansjörg Hauser, Manfred Rohde, Marcus Fulde, Mathias W Hornef, Tobias May

Source: PLoS ONE, Vol 8, Iss 8, p e72700 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3734307?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/87053de8df9d4453a3ef186acc95bcf5