Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes

Authors: Pervjakova, Natalia, Moen, Gunn-Helen, Borges, Maria-Carolina, Ferreira, Teresa, Cook, James P, Allard, Catherine, Beaumont, Robin N, Canouil, Mickaël, Hatem, Gad, Heiskala, Anni, Joensuu, Anni, Karhunen, Ville, Kwak, Soo Heon, Lin, Frederick T J, Liu, Jun, Rifas-Shiman, Sheryl, Tam, Claudia H, Tam, Wing Hung, Thorleifsson, Gudmar, Andrew, Toby, Auvinen, Juha, Bhowmik, Bishwajit, Bonnefond, Amélie, Delahaye, Fabien, Demirkan, Ayse, Froguel, Philippe, Haller-Kikkatalo, Kadri, Hardardottir, Hildur, Hummel, Sandra, Hussain, Akhtar, Kajantie, Eero, Keikkala, Elina, Khamis, Amna, Lahti, Jari, Lekva, Tove, Mustaniemi, Sanna, Sommer, Christine, Tagoma, Aili, Tzala, Evangelia, Uibo, Raivo, Vääräsmäki, Marja, Villa, Pia M, Birkeland, Kåre I, Bouchard, Luigi, Duijn, Cornelia M, Finer, Sarah, Groop, Leif, Hämäläinen, Esa, Hayes, Geoffrey M, Hitman, Graham A, Jang, Hak C, Järvelin, Marjo-Riitta, Jenum, Anne Karen, Laivuori, Hannele, Ma, Ronald C, Melander, Olle, Oken, Emily, Park, Kyong Soo, Perron, Patrice, Prasad, Rashmi B, Qvigstad, Elisabeth, Sebert, Sylvain, Stefansson, Kari, Steinthorsdottir, Valgerdur, Tuomi, Tiinamaija, Hivert, Marie-France, Franks, Paul W, McCarthy, Mark I, Lindgren, Cecilia M, Freathy, Rachel M, Lawlor, Deborah A, Morris, Andrew P, Mägi, Reedik

Source: Human molecular genetics. 31(19):3377-3391

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165175396.0x000001&indx=1&recIds=ETOCvdc_100165175396.0x000001

Food neophobia associates with poorer dietary quality, metabolic risk factors, and increased disease outcome risk in population-based cohorts in a metabolomics study

Authors: Sarin, Heikki V ^*, Taba, Nele, Fischer, Krista, Esko, Tonu, Kanerva, Noora, Moilanen, Leena, Saltevo, Juha, Joensuu, Anni, Borodulin, Katja, Männistö, Satu, Kristiansson, Kati, Perola, Markus

Source: In The American Journal of Clinical Nutrition July 2019 110(1):233-245

QSOX2 Deficiency-induced short stature, gastrointestinal dysmotility and immune dysfunction.

Authors: Maharaj, Avinaash V., Ishida, Miho, Rybak, Anna, Elfeky, Reem, Andrews, Afiya, Joshi, Aakash, Elmslie, Frances, Joensuu, Anni, Kantojärvi, Katri, Jia, Raina Y., Perry, John R. B., O'Toole, Edel A., McGuffin, Liam J., Hwa, Vivian, Storr, Helen L.

Source: Nature Communications; 9/28/2024, Vol. 15 Issue 1, p1-17, 17p

Subject Terms: MITOCHONDRIAL dynamics, PROTEIN disulfide isomerase, NUCLEAR membranes, MEMBRANE potential, HUMAN growth, PITUITARY dwarfism, SHORT stature

Metabolomics profile of 5649 users and nonusers of hormonal intrauterine devices in Finland

Authors: Toffol, Elena, Heikinheimo, Oskari, Jousilahti, Pekka, But, Anna, Joensuu, Anni, Latvala, Antti, Partonen, Timo, Erlund, Iris, Haukka, Jari

Source: In American Journal of Obstetrics and Gynecology October 2022 227(4):603-603

A metabolic profile of xenon and metabolite associations with 6-month mortality after out-of-hospital cardiac arrest: A post-hoc study of the randomised Xe-Hypotheca trial.

Authors: Nummela, Aleksi J., Scheinin, Harry, Perola, Markus, Joensuu, Anni, Laitio, Ruut, Arola, Olli, Grönlund, Juha, Roine, Risto O., Bäcklund, Minna, Vahlberg, Tero J., Laitio, Timo

Source: PLoS ONE; 6/4/2024, Vol. 19 Issue 6, p1-16, 16p

Subject Terms: CARDIAC arrest, NUCLEAR magnetic resonance spectroscopy, XENON, LACTATES, EXCITATORY amino acids, NEUROTRANSMITTERS, HDL cholesterol, AMINO acids

An interaction map of circulating metabolites, immune gene networks, and their genetic regulation

Authors: Nath, Artika, Ritchie, Scott, Byars, Sean, Fearnley, Liam, Havulinna, Aki, Joensuu, Anni, Kangas, Antti, Soininen, Pasi, Wennerström, Annika, Milani, Lili, Metspalu, Andres, Männistö, Satu, Würtz, Peter, Kettunen, Johannes, Raitoharju, Emma, Kähönen, Mika, Juonala, Markus, Palotie, Aarno, Ala-Korpela, Mika, Ripatti, Samuli, Lehtimäki, Terho, Abraham, Gad, Raitakari, Olli, Salomaa, Veikko, Perola, Markus, Inouye, Michael

Source: Genome biology. 18(1):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139988224.0x000001&indx=1&recIds=ETOCvdc_100139988224.0x000001

Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

Authors: Saleheen, Danish, Zhao, Wei, Young, Robin, Nelson, Christopher P., Ho, WeangKee, Ferguson, Jane F., Rasheed, Asif, Ou, Kristy, Nurnberg, Sylvia T., Bauer, Robert C., Goel, Anuj, Do, Ron, Stewart, Alexandre F.R., Hartiala, Jaana, Zhang, Weihua, Thorleifsson, Gudmar, Strawbridge, Rona J., Sinisalo, Juha, Kanoni, Stavroula, Sedaghat, Sanaz, Marouli, Eirini, Kristiansson, Kati, Hua Zhao, Jing, Scott, Robert, Gauguier, Dominique, Shah, Svati H., Smith, Albert Vernon, van Zuydam, Natalie, Cox, Amanda J., Willenborg, Christina, Kessler, Thorsten, Zeng, Lingyao, Province, Michael A., Ganna, Andrea, Lind, Lars, Pedersen, Nancy L., White, Charles C., Joensuu, Anni, Edi Kleber, Marcus, Hall, Alistair S., März, Winfried, Salomaa, Veikko, O’Donnell, Christopher, Ingelsson, Erik, Feitosa, Mary F., Erdmann, Jeanette, Bowden, Donald W., Palmer, Colin N.A., Gudnason, Vilmundur, Faire, Ulf De, Zalloua, Pierre, Wareham, Nicholas, Thompson, John R., Kuulasmaa, Kari, Dedoussis, George, Perola, Markus, Dehghan, Abbas, Chambers, John C., Kooner, Jaspal, Allayee, Hooman, Deloukas, Panos, McPherson, Ruth, Stefansson, Kari, Schunkert, Heribert, Kathiresan, Sekar, Farrall, Martin, Marcel Frossard, Philippe, Rader, Daniel J., Samani, Nilesh J., Reilly, Muredach P.

Source: Circulation. 135(24):2336-2353

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100044958821.0x000001&indx=1&recIds=ETOCvdc_100044958821.0x000001

An epigenome-wide association study of metabolic syndrome and its components

Authors: Nuotio, Marja-Liisa, Pervjakova, Natalia, Joensuu, Anni, Karhunen, Ville, Hiekkalinna, Tero, Milani, Lili, Kettunen, Johannes, Järvelin, Marjo-Riitta, Jousilahti, Pekka, Metspalu, Andres, Salomaa, Veikko, Kristiansson, Kati, Perola, Markus

Source: Scientific reports. 10(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190737323.0x000001&indx=1&recIds=ETOCvdc_100190737323.0x000001

A distinctive DNA methylation pattern in insufficient sleep

Authors: Lahtinen, Alexandra, Puttonen, Sampsa, Vanttola, Päivi, Viitasalo, Katriina, Sulkava, Sonja, Pervjakova, Natalia, Joensuu, Anni, Salo, Perttu, Toivola, Auli, Härmä, Mikko, Milani, Lili, Perola, Markus, Paunio, Tiina

Source: Scientific reports. 9(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131291751.0x000001&indx=1&recIds=ETOCvdc_100131291751.0x000001

Search for Early Pancreatic Cancer Blood Biomarkers in Five European Prospective Population Biobanks Using Metabolomics.

Authors: Fest, Jesse, Vijfhuizen, Lisanne S, Goeman, Jelle J, Veth, Olga, Joensuu, Anni, Perola, Markus, Männistö, Satu, Ness-Jensen, Eivind, Hveem, Kristian, Haller, Toomas, Tonisson, Neeme, Mikkel, Kairit, Metspalu, Andres, Duijn, Cornelia M van, Ikram, Arfan, Stricker, Bruno H, Ruiter, Rikje, Eijck, Casper H J van, Ommen, Gert-Jan B van, Hoen, Peter A C ʼt

Source: Endocrinology; Jul2019, Vol. 160 Issue 7, p1731-1742, 12p

Associations of increased physical performance and change in body composition with molecular pathways of heart disease and diabetes risk.

Authors: Kettunen, Johannes^1,2,3 johannes.kettunen@oulu.fi, Joensuu, Anni^1,4,5, Hagnäs, Maria^6,7, Mikkola, Ilona⁷, Wennerström, Annika^1,4, Lee, Joseph H.⁸, Terwilliger, Joseph D.^1,9,10, Borodulin, Katja¹, Jousilahti, Pekka¹, Jauhiainen, Matti^1,11, Jokelainen, Jari J.^6,12, Keinänen-Kiukaanniemi, Sirkka^6,12,13, Perola, Markus^1,5

Source: American Journal of Physiology: Endocrinology & Metabolism. Feb2019, Vol. 316 Issue 2, pE221-E229. 9p.

Subject Terms: *PHYSICAL activity, *HEART disease risk factors, *DIABETES risk factors

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Loss of Cardioprotective Effects at the ADAMTS7Locus as a Result of Gene-Smoking Interactions

Authors: Saleheen, Danish, Zhao, Wei, Young, Robin, Nelson, Christopher P., Ho, WeangKee, Ferguson, Jane F., Rasheed, Asif, Ou, Kristy, Nurnberg, Sylvia T., Bauer, Robert C., Goel, Anuj, Do, Ron, Stewart, Alexandre F.R., Hartiala, Jaana, Zhang, Weihua, Thorleifsson, Gudmar, Strawbridge, Rona J., Sinisalo, Juha, Kanoni, Stavroula, Sedaghat, Sanaz, Marouli, Eirini, Kristiansson, Kati, Hua Zhao, Jing, Scott, Robert, Gauguier, Dominique, Shah, Svati H., Smith, Albert Vernon, van Zuydam, Natalie, Cox, Amanda J., Willenborg, Christina, Kessler, Thorsten, Zeng, Lingyao, Province, Michael A., Ganna, Andrea, Lind, Lars, Pedersen, Nancy L., White, Charles C., Joensuu, Anni, Edi Kleber, Marcus, Hall, Alistair S., März, Winfried, Salomaa, Veikko, O’Donnell, Christopher, Ingelsson, Erik, Feitosa, Mary F., Erdmann, Jeanette, Bowden, Donald W., Palmer, Colin N.A., Gudnason, Vilmundur, Faire, Ulf De, Zalloua, Pierre, Wareham, Nicholas, Thompson, John R., Kuulasmaa, Kari, Dedoussis, George, Perola, Markus, Dehghan, Abbas, Chambers, John C., Kooner, Jaspal, Allayee, Hooman, Deloukas, Panos, McPherson, Ruth, Stefansson, Kari, Schunkert, Heribert, Kathiresan, Sekar, Farrall, Martin, Marcel Frossard, Philippe, Rader, Daniel J., Samani, Nilesh J., Reilly, Muredach P.

Source: Circulation (Ovid); June 2017, Vol. 135 Issue: 24 p2336-2353, 18p

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