Genome-wide DNA methylation analysis reveals a unique methylation pattern for pleural mesothelioma compared to healthy pleura and other lung diseases

Authors: Janah Vandenhoeck, Joe Ibrahim, Nele De Meulenaere, Dieter Peeters, Jo Raskin, Jeroen M. H. Hendriks, Paul Van Schil, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck

Source: Clinical Epigenetics, Vol 16, Iss 1, Pp 1-17 (2024)

Subject Terms: Epigenetics, DNA methylation, Pleural mesothelioma, Lung cancer, Healthy pleura, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/af16fa6948c043a6a1663eb565744f43

ADNP dysregulates methylation and mitochondrial gene expression in the cerebellum of a Helsmoortel–Van der Aa syndrome autopsy case

Authors: Claudio D’Incal, Anke Van Dijck, Joe Ibrahim, Kevin De Man, Lina Bastini, Anthony Konings, Ellen Elinck, Claudia Theys, Illana Gozes, Zlatko Marusic, Mirna Anicic, Jurica Vukovic, Nathalie Van der Aa, Ligia Mateiu, Wim Vanden Berghe, R. Frank Kooy

Source: Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-32 (2024)

Subject Terms: Activity-dependent neuroprotective protein (ADNP), Methylation, Chromatin remodeler, Autophagy, Mitochondria, Post-mortem brain, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/0d40e2e4341b4789a86693c044db578c

Correction to: ADNP dysregulates methylation and mitochondrial gene expression in the cerebellum of a Helsmoortel–Van Der Aa syndrome autopsy case

Authors: Claudio D’Incal, Anke Van Dijck, Joe Ibrahim, Kevin De Man, Lina Bastini, Anthony Konings, Ellen Elinck, Claudia Theys, Illana Gozes, Zlatko Marusic, Mirna Anicic, Jurica Vukovic, Nathalie Van der Aa, Ligia Mateiu, Wim Vanden Berghe, R. Frank Kooy

Source: Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-2 (2024)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/b928ddfb380e499fa1895bcd254f3a11

Epigenome-wide methylation analysis of colorectal carcinoma, adenoma and normal tissue reveals novel biomarkers addressing unmet clinical needs

Authors: Katleen Janssens, Isabelle Neefs, Joe Ibrahim, Anne Schepers, Patrick Pauwels, Marc Peeters, Guy Van Camp, Ken Op de Beeck

Source: Clinical Epigenetics, Vol 15, Iss 1, Pp 1-14 (2023)

Subject Terms: Colorectal cancer, Methylation, Biomarkers, Adenoma, Carcinoma, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/f0195dd157dc48ceb7a73e17eb3bb1f3

Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver disease (MASLD)

Authors: Claudia Theys, Tineke Vanderhaeghen, Evelien Van Dijck, Cedric Peleman, Anne Scheepers, Joe Ibrahim, Ligia Mateiu, Steven Timmermans, Tom Vanden Berghe, Sven M. Francque, Wim Van Hul, Claude Libert, Wim Vanden Berghe

Source: Frontiers in Molecular Medicine, Vol 3 (2024)

Subject Terms: PPARα, MASLD, epigenetics, lipid metabolism, bile acid metabolism, NAFLD, Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmmed.2023.1283170/full; https://doaj.org/toc/2674-0095

Access URL: https://doaj.org/article/949581703c6a48e18ffca39d01ec79c1

Genome‐wide DNA methylation profiling and identification of potential pan‐cancer and tumor‐specific biomarkers

Authors: Joe Ibrahim, Ken Op de Beeck, Erik Fransen, Marc Peeters, Guy Van Camp

Source: Molecular Oncology, Vol 16, Iss 12, Pp 2432-2447 (2022)

Subject Terms: biomarker, cancer, genome‐wide analysis, methylation, pan‐cancer, tumor‐specific, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/2ca2c857bdde42a083414deb0e1debb3

Methylation analysis of Gasdermin E shows great promise as a biomarker for colorectal cancer

Authors: Joe Ibrahim, Ken Op de Beeck, Erik Fransen, Lieselot Croes, Matthias Beyens, Arvid Suls, Wim Vanden Berghe, Marc Peeters, Guy Van Camp

Source: Cancer Medicine, Vol 8, Iss 5, Pp 2133-2145 (2019)

Subject Terms: Biomarker, Colorectal cancer, Diagnosis, DNA methylation, GSDME, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/1cc3393c017c48889df81d998ea79a64

Gene set enrichment analysis reveals a first somatic mutation in the catalytic domain of MAP2K1 in a melorheostosis patient

Authors: Raphaël De Ridder, Eveline Boudin, Joe Ibrahim, M. Carola Zillikens, Bram C.J. van der Eerden, Wim Van Hul, Geert Mortier

Source: Bone Reports, Vol 13, Iss , Pp 100357- (2020)

Subject Terms: Diseases of the musculoskeletal system, RC925-935

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352187220301170; https://doaj.org/toc/2352-1872

Access URL: https://doaj.org/article/cffa2985aaef45b49222e65ef2cc5f82

Large-scale analysis of DFNA5 methylation reveals its potential as biomarker for breast cancer

Authors: Lieselot Croes, Matthias Beyens, Erik Fransen, Joe Ibrahim, Wim Vanden Berghe, Arvid Suls, Marc Peeters, Patrick Pauwels, Guy Van Camp, Ken Op de Beeck

Source: Clinical Epigenetics, Vol 10, Iss 1, Pp 1-13 (2018)

Subject Terms: DFNA5, Methylation, Breast cancer, Detection biomarker, Prognostic biomarker, TCGA, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13148-018-0479-y; https://doaj.org/toc/1868-7075; https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/f98387d6fee148ac9903d728ce27f83b

The technology landscape for detection of DNA methylation in cancer liquid biopsies

Authors: Isabelle Neefs, Joe Ibrahim, Marc Peeters, Guy Van Camp, Ken Op de Beeck

Source: Epigenetics, Vol 20, Iss 1 (2025)

Subject Terms: DNA methylation, detection, cancer, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1559-2294; https://doaj.org/toc/1559-2308

Access URL: https://doaj.org/article/bea790b053e841fc834264dfb1cf9ed0

Genome Analysis of Streptococcus pyogenes Associated with Pharyngitis and Skin Infections.

Authors: Joe Ibrahim, Jonathan A Eisen, Guillaume Jospin, David A Coil, Georges Khazen, Sima Tokajian

Source: PLoS ONE, Vol 11, Iss 12, p e0168177 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5158041?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/db0b08de4f724553a711c6ca6fbc6a51