Concomitant inhibition of the thioredoxin system and nonhomologous DNA repair potently sensitizes Philadelphia‐positive lymphoid leukemia to tyrosine kinase inhibitors

Authors: Lukasz Komorowski, Agnieszka Dabkowska, Joanna Madzio, Agata Pastorczak, Kacper Szczygiel, Martyna Janowska, Klaudyna Fidyt, Maksymilian Bielecki, Jaromir Hunia, Malgorzata Bajor, Tomasz Stoklosa, Magdalena Winiarska, Elzbieta Patkowska, Malgorzata Firczuk

Source: HemaSphere, Vol 8, Iss 3, Pp n/a-n/a (2024)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/63c5498d4ac84ee299403fabe44603ba

The paradox of autoimmunity and autoinflammation in inherited neutrophil disorders – in search of common patterns

Authors: Damian Krzyzanowski, Aleksandra Oszer, Joanna Madzio, Maciej Zdunek, Julia Kolodrubiec, Bartosz Urbanski, Wojciech Mlynarski, Szymon Janczar

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: neutropenia, chronic granulomatous disease, autoimmunity, inflammatory bowel disease, autoinflammation, severe congenital neutropenia, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1128581/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/f4dca9757e184936ac5e26c274330279

Clinical and laboratory diversity of diffuse large B-cell lymphomas in children with Nijmegen breakage syndrome

Authors: Agata Pastorczak, Bartosz Szmyd, Marcin Braun, Joanna Madzio, Kamila Wypyszczak, Pawel Sztromwasser, Wojciech Fendler, Marzena Wojtaszewska, Jedrzej Chrzanowski, Wieslawa Grajkowska, Hanna Gregorek, Anna Wakulinska, Bernarda Kazanowska, Zdenka Krenova, Dilys D. Weijers, Roland P. Kuiper, Wojciech Mlynarski

Source: Haematologica, Vol 108, Iss 10 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/11041; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/98fb008f6de641828a6b3d6bc7fcbdca

The kinetics of blast clearance are associated with copy number alterations in childhood B-cell acute lymphoblastic leukemia

Authors: Zuzanna Urbańska, Monika Lejman, Joanna Taha, Joanna Madzio, Kinga Ostrowska, Karolina Miarka-Walczyk, Kamila Wypyszczak, Borys Styka, Justyna Jakubowska, Łukasz Sędek, Tomasz Szczepański, Marcin Stańczak, Wojciech Fendler, Wojciech Młynarski, Agata Pastorczak

Source: Neoplasia: An International Journal for Oncology Research, Vol 35, Iss , Pp 100840- (2023)

Subject Terms: Acute lymphoblastic leukemia, Children, Chemoresistance, Copy number alterations, Minimal residual disease, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558622000665; https://doaj.org/toc/1476-5586

Access URL: https://doaj.org/article/34f74e221bac4925ae4720cc46ce51ba

Targeting the thioredoxin system as a novel strategy against B‐cell acute lymphoblastic leukemia

Authors: Klaudyna Fidyt, Agata Pastorczak, Agnieszka Goral, Kacper Szczygiel, Wojciech Fendler, Angelika Muchowicz, Marcin Adam Bartlomiejczyk, Joanna Madzio, Julia Cyran, Agnieszka Graczyk‐Jarzynka, Eugene Jansen, Elzbieta Patkowska, Ewa Lech‐Maranda, Deepali Pal, Helen Blair, Anna Burdzinska, Piotr Pedzisz, Eliza Glodkowska‐Mrowka, Urszula Demkow, Karolina Gawle‐Krawczyk, Michal Matysiak, Magdalena Winiarska, Przemyslaw Juszczynski, Wojciech Mlynarski, Olaf Heidenreich, Jakub Golab, Malgorzata Firczuk

Source: Molecular Oncology, Vol 13, Iss 5, Pp 1180-1195 (2019)

Subject Terms: ALL, antioxidant enzymes, leukemia, oxidative stress, peroxiredoxin, thioredoxin, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/45a979d9ef364d65aa674b4bb09f8254

Neutrophil Elastase Defects in Congenital Neutropenia

Authors: Zuzanna Rydzynska, Bartlomiej Pawlik, Damian Krzyzanowski, Wojciech Mlynarski, Joanna Madzio

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: severe congenital neutropenia, cyclic neutropenia, neutrophil elastase, ELANE mutations, unfolded protein response, mistrafficking, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.653932/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/f64cb48e5909418da21340639b19c497

Heterozygous carriers of germline c.657_661del5 founder mutation in NBN gene are at risk of central nervous system relapse of B-cell precursor acute lymphoblastic leukemia

Authors: Bartłomiej Tomasik, Agata Pastorczak, Wojciech Fendler, Marcin Bartłomiejczyk, Marcin Braun, Marcin Mycko, Joanna Madzio, Ewa Polakowska, Edyta Ulińska, Michał Matysiak, Katarzyna Derwich, Monika Lejman, Jerzy Kowalczyk, Wanda Badowska, Bernarda Kazanowska, Tomasz Szczepański, Jan Styczyński, Nina Irga-Jaworska, Wojciech Młynarski

Source: Haematologica, Vol 103, Iss 5 (2018)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/8467; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/6b8ac98a45724baa8f246ea11bdca1f3