The dual GLP-1/glucagon receptor agonist G49 mimics bariatric surgery effects by inducing metabolic rewiring and inter-organ crosstalk

Authors: M. Pilar Valdecantos, Laura Ruiz, Cintia Folgueira, Patricia Rada, Beatriz Gomez-Santos, Maite Solas, Ana B. Hitos, Joss Field, Vera Francisco, Carmen Escalona-Garrido, Sebastián Zagmutt, María Calderon-Dominguez, Paula Mera, Irma Garcia-Martinez, Elsa Maymó-Masip, Diana Grajales, Rosa Alen, Alfonso Mora, Neira Sáinz, Irene Vides-Urrestarazu, Nuria Vilarrasa, José M. Arbones-Mainar, Carlos Zaragoza, María J. Moreno-Aliaga, Patricia Aspichueta, Sonia Fernández-Veledo, Joan Vendrell, Dolors Serra, Laura Herrero, Renate Schreiber, Rudolf Zechner, Guadalupe Sabio, David Hornigold, Cristina M. Rondinone, Lutz Jermutus, Joseph Grimsby, Ángela M. Valverde

Source: Nature Communications, Vol 15, Iss 1, Pp 1-29 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/6e46df4151b04affa21678e1243d004d

Time-restricted eating, the clock ticking behind the scenes

Authors: Aleix Ribas-Latre, Sonia Fernández-Veledo, Joan Vendrell

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: obesity, intermittent fasting, time-restricted eating, chronotype, circadian rhythms, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1428601/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/f088e6f5e94d4b8c850be1cba50fdbba

A specific gut microbiota signature is associated with an enhanced GLP-1 and GLP-2 secretion and improved metabolic control in patients with type 2 diabetes after metabolic Roux-en-Y gastric bypass

Authors: Laura Hernández-Montoliu, M-Mar Rodríguez-Peña, Rocío Puig, Brenno Astiarraga, Fernando Guerrero-Pérez, Nuria Virgili, Rafael López-Urdiales, Javier Osorio, Rosa Monseny, Claudio Lazzara, Lucía Sobrino, Manuel Pérez-Maraver, María Pérez-Prieto, Silvia Pellitero, Sonia Fernández-Veledo, Joan Vendrell, Nuria Vilarrasa

Source: Frontiers in Endocrinology, Vol 14 (2023)

Subject Terms: incretin, microbiota, type 2 diabetes remission, severe obesity, bariatric surgery, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2023.1181744/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/f42fc369fb3544ab89c734e234d8bbff

Orally administered Odoribacter laneus improves glucose control and inflammatory profile in obese mice by depleting circulating succinate

Authors: Isabel Huber-Ruano, Enrique Calvo, Jordi Mayneris-Perxachs, M-Mar Rodríguez-Peña, Victòria Ceperuelo-Mallafré, Lídia Cedó, Catalina Núñez-Roa, Joan Miro-Blanch, María Arnoriaga-Rodríguez, Aurélie Balvay, Claire Maudet, Pablo García-Roves, Oscar Yanes, Sylvie Rabot, Ghjuvan Micaelu Grimaud, Annachiara De Prisco, Angela Amoruso, José Manuel Fernández-Real, Joan Vendrell, Sonia Fernández-Veledo

Source: Microbiome, Vol 10, Iss 1, Pp 1-22 (2022)

Subject Terms: Succinate, Obesity, Probiotics, Animal models, Inflammation, Glucose tolerance, Microbial ecology, QR100-130

File Description: electronic resource

Relation: https://doaj.org/toc/2049-2618

Access URL: https://doaj.org/article/a570aa898a594f34ad77716587a8d6a4

Correction: The angiogenic properties of human amniotic membrane stem cells are enhanced in gestational diabetes and associate with fetal adiposity

Authors: Sergiy Klid, Francisco Algaba-Chueca, Elsa Maymó-Masip, Albert Guarque, Mónica Ballesteros, Cristina Diaz-Perdigones, Cristina Gutierrez, Joan Vendrell, Ana Megía, Sonia Fernández-Veledo

Source: Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-2 (2023)

Subject Terms: Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/c9ee87fc79ad4aa0b6edfd8ab6d2f11b

CDK4 is an essential insulin effector in adipocytes

Authors: Sylviane Lagarrigue, Isabel C. Lopez-Mejia, Pierre-Damien Denechaud, Xavier Escoté, Judit Castillo-Armengol, Veronica Jimenez, Carine Chavey, Albert Giralt, Qiuwen Lai, Lianjun Zhang, Laia Martinez-Carreres, Brigitte Delacuisine, Jean-Sébastien Annicotte, Emilie Blanchet, Sébastien Huré, Anna Abella, Francisco J. Tinahones, Joan Vendrell, Pierre Dubus, Fatima Bosch, C. Ronald Kahn, Lluis Fajas

Source: The Journal of Clinical Investigation, Vol 133, Iss 6 (2023)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/1453ec066ed340c8a243912c98d2ac0f

The angiogenic properties of human amniotic membrane stem cells are enhanced in gestational diabetes and associate with fetal adiposity

Authors: Sergiy Klid, Francisco Algaba-Chueca, Elsa Maymó-Masip, Albert Guarque, Mónica Ballesteros, Cristina Diaz-Perdigones, Cristina Gutierrez, Joan Vendrell, Ana Megía, Sonia Fernández-Veledo

Source: Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-13 (2021)

Subject Terms: Human amniotic stem cells, Gestational diabetes, Angiogenesis, Neonatal adiposity, Cord blood insulin, PAI-1, Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/a9d5d62b44924cb79ebba869f11469cb

Elevated plasma succinate levels are linked to higher cardiovascular disease risk factors in young adults

Authors: Francisco J. Osuna-Prieto, Borja Martinez-Tellez, Lourdes Ortiz-Alvarez, Xinyu Di, Lucas Jurado-Fasoli, Huiwen Xu, Victoria Ceperuelo-Mallafré, Catalina Núñez-Roa, Isabelle Kohler, Antonio Segura-Carretero, José V. García-Lario, Angel Gil, Concepción M. Aguilera, Jose M. Llamas-Elvira, Patrick C. N. Rensen, Joan Vendrell, Jonatan R. Ruiz, Sonia Fernández-Veledo

Source: Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-10 (2021)

Subject Terms: Obesity, Visceral adiposity, Inflammation, Oxylipins, Succinate, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2840

Access URL: https://doaj.org/article/fb1bf7ad288e4c6ab546b24aea75d0c6

Effects of stem cells from inducible brown adipose tissue on diet-induced obesity in mice

Authors: Enrique Calvo, Noelia Keiran, Catalina Núñez-Roa, Elsa Maymó-Masip, Miriam Ejarque, Joan Sabadell-Basallote, María del Mar Rodríguez-Peña, Victòria Ceperuelo-Mallafré, Jesús Seco, Ester Benaiges, Theodora Michalopoulou, Rosa Jorba, Joan Vendrell, Sonia Fernández-Veledo

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/27e8a7169a344c70913c6bfca80e9cd0

Circulating pyruvate is a potent prognostic marker for critical COVID-19 outcomes

Authors: Victòria Ceperuelo-Mallafré, Laia Reverté, Joaquim Peraire, Ana Madeira, Elsa Maymó-Masip, Miguel López-Dupla, Alicia Gutierrez-Valencia, Ezequiel Ruiz-Mateos, Maria José Buzón, Rosa Jorba, Joan Vendrell, Teresa Auguet, Montserrat Olona, Francesc Vidal, Anna Rull, Sonia Fernández-Veledo

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: COVID-19, energy-related metabolites, fluorometric quantification, pyruvate, semi-targeted metebolomics, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.912579/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/0344fdd1c16e48c4b010ac161ede07db

Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue

Authors: Alba Gonzalez-Franquesa, Pau Gama-Perez, Marta Kulis, Karolina Szczepanowska, Norma Dahdah, Sonia Moreno-Gomez, Ana Latorre-Pellicer, Rebeca Fernández-Ruiz, Antoni Aguilar-Mogas, Anne Hoffman, Erika Monelli, Sara Samino, Joan Miró-Blanch, Gregor Oemer, Xavier Duran, Estrella Sanchez-Rebordelo, Marc Schneeberger, Merce Obach, Joel Montane, Giancarlo Castellano, Vicente Chapaprieta, Wenfei Sun, Lourdes Navarro, Ignacio Prieto, Carlos Castaño, Anna Novials, Ramon Gomis, Maria Monsalve, Marc Claret, Mariona Graupera, Guadalupe Soria, Christian Wolfrum, Joan Vendrell, Sonia Fernández-Veledo, Jose Antonio Enríquez, Angel Carracedo, José Carlos Perales, Rubén Nogueiras, Laura Herrero, Aleksandra Trifunovic, Markus A. Keller, Oscar Yanes, Marta Sales-Pardo, Roger Guimerà, Matthias Blüher, José Ignacio Martín-Subero, Pablo M. Garcia-Roves

Source: Redox Biology, Vol 54, Iss , Pp 102353- (2022)

Subject Terms: Obesity, Metabolic plasticity, Visceral adipose tissue, Mitochondrial dysfunction, Exercise, Caloric restriction, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231722001252; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/ad594c8df2c8447b85a354bfb7fa6b81

CDK4 is an essential insulin effector in adipocytes

Authors: Sylviane Lagarrigue, Isabel C. Lopez-Mejia, Pierre-Damien Denechaud, Xavier Escoté, Judit Castillo-Armengol, Veronica Jimenez, Carine Chavey, Albert Giralt, Qiuwen Lai, Lianjun Zhang, Laia Martinez-Carreres, Brigitte Delacuisine, Jean-Sébastien Annicotte, Emilie Blanchet, Sébastien Huré, Anna Abella, Francisco J. Tinahones, Joan Vendrell, Pierre Dubus, Fatima Bosch, C. Ronald Kahn, Lluis Fajas

Source: The Journal of Clinical Investigation, Vol 132, Iss 13 (2022)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/4642ee6f471f48639eb3b9f1fb308211

New Insights in Cytokines in Childhood Obesity: Changes in TWEAK and CD163 After a 2-Year Intervention Program in Prepubertal Children With Obesity

Authors: Rocío Escartín, Maria Font, José Miguel González-Clemente, Joan Vendrell, Assumpta Caixàs, Raquel Corripio

Source: Frontiers in Endocrinology, Vol 13 (2022)

Subject Terms: TWEAK, CD163, childhood, obesity, prepubertal, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2022.909201/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/1d69e0bc960c4ccfa72b957176b71b36

Diabetes alters the protein secretome of human adipose‐derived stem cells and promotes tumorigenesis in hepatic cancer cells

Authors: Miriam Ejarque, Joan Sabadell‐Basallote, Ester Benaiges, Catalina Núñez‐Roa, Eduardo Sabido, Eva Borras, Erik Llacer, Antonio Zorzano, Joan Vendrell, Sonia Fernández‐Veledo

Source: Clinical and Translational Medicine, Vol 12, Iss 6, Pp n/a-n/a (2022)

Subject Terms: Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/dcc5c8b41b5d4fc8bb83542bb191338c

Changes in glucagon‐like peptide 1 and 2 levels in people with obesity after a diet‐induced weight‐loss intervention are related to a specific microbiota signature: A prospective cohort study

Authors: M‐Mar Rodríguez‐Peña, Brenno Astiarraga, Jesus Seco, Victoria Ceperuelo‐Mallafré, Adrià Caballé, Vicente Pérez‐Brocal, Camille Stephan‐Otto Attolini, Andrés Moya, Gemma Llauradó, Ana Megía, Silvia Pellitero, Núria Vilarrasa, Sonia Fernández‐Veledo, Joan Vendrell

Source: Clinical and Translational Medicine, Vol 11, Iss 11, Pp n/a-n/a (2021)

Subject Terms: Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/5fba93acbb654bf096084f04bf8708bf

Gestational diabetes impacts fetal precursor cell responses with potential consequences for offspring

Authors: Francisco Algaba‐Chueca, Elsa Maymó‐Masip, Miriam Ejarque, Mónica Ballesteros, Gemma Llauradó, Carlos López, Albert Guarque, Carolina Serena, Laia Martínez‐Guasch, Cristina Gutiérrez, Ramón Bosch, Joan Vendrell, Ana Megía, Sonia Fernández‐Veledo

Source: Stem Cells Translational Medicine, Vol 9, Iss 3, Pp 351-363 (2020)

Subject Terms: fetal precursors, gestational diabetes, offspring, placenta, programming, stem cells, Medicine (General), R5-920, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2157-6564; https://doaj.org/toc/2157-6580

Access URL: https://doaj.org/article/d8535325c56d437fa08c8e4501703d89

Impaired mRNA splicing and proteostasis in preadipocytes in obesity-related metabolic disease

Authors: Julia Sánchez-Ceinos, Rocío Guzmán-Ruiz, Oriol Alberto Rangel-Zúñiga, Jaime López-Alcalá, Elena Moreno-Caño, Mercedes Del Río-Moreno, Juan Luis Romero-Cabrera, Pablo Pérez-Martínez, Elsa Maymo-Masip, Joan Vendrell, Sonia Fernández-Veledo, José Manuel Fernández-Real, Jurga Laurencikiene, Mikael Rydén, Antonio Membrives, Raul M Luque, José López-Miranda, María M Malagón

Source: eLife, Vol 10 (2021)

Subject Terms: preadipocytes, obesity-related metabolic diseases, RNA splicing, ER-proteostasis, UPR, ERAD, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/65996; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/af1e565ee14b40e49f3a99c51d6ad84c

Walnuts, Long-Chain Polyunsaturated Fatty Acids, and Adolescent Brain Development: Protocol for the Walnuts Smart Snack Dietary Intervention Trial

Authors: Jordi Julvez, Florence Gignac, Silvia Fernández-Barrés, Dora Romaguera, Aleix Sala-Vila, Otavio T. Ranzani, Cecilia Persavento, Anna Delgado, Albert Carol, Jaume Torrent, Judith Gonzalez, Eduard Roso, Jose Barrera-Gómez, Mónica López-Vicente, Raquel Garcia-Esteban, Olivier Boucher, Joan Forns, Miguel Burgaleta, Nuria Sebastián, Josefina Canals, Victoria Arija, Xavier Basagaña, Emilio Ros, Joan Vendrell, Jordi Salas-Salvadó, Jordi Sunyer

Source: Frontiers in Pediatrics, Vol 9 (2021)

Subject Terms: neuropsychological development, dietary intervention, walnuts, omega-3 PUFA, ALA, randomized controlled trial, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fped.2021.593847/full; https://doaj.org/toc/2296-2360

Access URL: https://doaj.org/article/e9bb4f7ab20641b0ab2de55aab07dba3

Quantum-Inspired Evolutionary Algorithm for Optimal Service-Matching Task Assignment

Authors: Joan Vendrell, Solmaz Kia

Source: Information, Vol 13, Iss 9, p 438 (2022)

Subject Terms: quantum-inspired evolutionary algorithm, service-matching task assignment, greedy algorithm, Hungarian method, Simplex, Information technology, T58.5-58.64

File Description: electronic resource

Relation: https://www.mdpi.com/2078-2489/13/9/438; https://doaj.org/toc/2078-2489

Access URL: https://doaj.org/article/1251c47f17f9484d94c56e67a5bbee3d

Cord Blood Advanced Lipoprotein Testing Reveals an Interaction between Gestational Diabetes and Birth-Weight and Suggests a New Early Biomarker of Infant Obesity

Authors: Francisco Algaba-Chueca, Elsa Maymó-Masip, Mónica Ballesteros, Albert Guarque, Alejandro Majali-Martínez, Olga Freixes, Núria Amigó, Sonia Fernández-Veledo, Joan Vendrell, Ana Megía

Source: Biomedicines, Vol 10, Iss 5, p 1033 (2022)

Subject Terms: birth-weight, gestational diabetes, lipoprotein profile, obesity, fetal blood, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/10/5/1033; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/1facf9d359574f339221c7b3fc324df9