A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates IGF1R gene expression

Authors: Chrudinová, Martina, Kirk, Nicholas S., Chuard, Aurelien, Venugopal, Hari, Zhang, Fa, Lubos, Marta, Gelfanov, Vasily, Páníková, Terezie, Žáková, Lenka, Cutone, Julianne, Mojares, Matthew, DiMarchi, Richard, Jiráček, Jiří, Altindis, Emrah

Source: In Molecular Metabolism February 2024 80

Chiral analysis of β‐alanyl‐d, l‐tyrosine and its derivatives and estimation of binding constants of their complexes with 2‐hydroxypropyl‐β‐cyclodextrin by capillary electrophoresis

Authors: Sázelová, Petra, Šolínová, Veronika, Schimperková, Tereza, Jiráček, Jiří, Kašička, Václav

Source: Journal of separation science. 45(17):3328-3338

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100159918720.0x000001&indx=1&recIds=ETOCvdc_100159918720.0x000001

Functional stapled fragments of human preptin of minimised lengthElectronic supplementary information (ESI) available. See DOI: 10.1039/d1ob02193a

Authors: Lubos, Marta, Mrázková, Lucie, Gwozdiaková, Petra, Pícha, Jan, Buděšínský, Miloš, Jiráček, Jiří, Kaminský, Jakub, Žáková, Lenka

Source: Organic & biomolecular chemistry. 20(12):2446-2454

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100144716596.0x000001&indx=1&recIds=ETOCvdc_100144716596.0x000001

Characterization of viral insulins reveals white adipose tissue-specific effects in mice

Authors: Chrudinová, Martina, Moreau, François, Noh, Hye Lim, Páníková, Terezie, Žáková, Lenka, Friedline, Randall H., Valenzuela, Francisco A., Kim, Jason K., Jiráček, Jiří, Kahn, C. Ronald, Altindis, Emrah

Source: In Molecular Metabolism February 2021 44

Multipodal insulin mimetics built on adamantane or proline scaffolds

Authors: Hajduch, Jan, Fabre, Benjamin, Klopp, Benjamin, Pohl, Radek, Buděšínský, Miloš, Šolínová, Veronika, Kašička, Václav, Köprülüoglu, Cemal, Eyrilmez, Saltuk Mustafa, Lepšík, Martin, Hobza, Pavel, Mitrová, Katarína, Lubos, Marta, Hernández, María Soledad Garre, Jiráček, Jiří

Source: In Bioorganic Chemistry February 2021 107

Modulation of the antagonistic properties of an insulin mimetic peptide by disulfide bridge modifications

Authors: Lubos, Marta, Pícha, Jan, Selicharová, Irena, Žák, Jíří, Buděšínský, Miloš, Mitrová, Katarína, Žáková, Lenka, Jiráček, Jiří

Source: Journal of peptide science. 29(7)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100184689872.0x000001&indx=1&recIds=ETOCvdc_100184689872.0x000001

Targeting the insulin receptor with hormone and peptide dimers

Authors: Lin, Jingjing, Selicharová, Irena, Mitrová, Katarína, Fabre, Benjamin, Miriyala, Vijay Madhav, Lepšík, Martin, Jiráček, Jiří, Hernández, María Soledad Garre

Source: Journal of peptide science. 29(4)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100177020878.0x000001&indx=1&recIds=ETOCvdc_100177020878.0x000001

Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2 result in receptor- and hormone-specific responses

Alternate Title: Insulin and IGFs respond to equivalent mutations differently (English)

Authors: Macháčková, Kateřina, Mlčochová, Květoslava, Potalitsyn, Pavlo, Hanková, Kateřina, Socha, Ondřej, Buděšínský, Miloš, Muždalo, Anja, Lepšík, Martin, Černeková, Michaela, Radosavljević, Jelena, Fábry, Milan, Mitrová, Katarína, Chrudinová, Martina, Lin, Jingjing, Yurenko, Yevgen, Hobza, Pavel, Selicharová, Irena, Žáková, Lenka, Jiráček, Jiří

Source: In Journal of Biological Chemistry 15 November 2019 294(46):17371-17382

Pressure assisted partial filling affinity capillary electrophoresis employed for determination of binding constants of human insulin hexamer complexes with serotonin, dopamine, arginine, and phenol

Authors: Šolínová, Veronika, Žáková, Lenka, Jiráček, Jiří, Kašička, Václav

Source: In Analytica Chimica Acta 4 April 2019 1052:170-178

Radiolabeled hormones in insulin research, a minireview

Authors: Jiráček, Jiří, Žáková, Lenka, Marek, Aleš

Source: Journal of labelled compounds & radiopharmaceuticals. 63(14):576-581

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111881903.0x000001&indx=1&recIds=ETOCvdc_100111881903.0x000001

Acid‐Stable Ester Linkers for the Solid‐Phase Synthesis of Immobilized Peptides

Authors: Pícha, Jan, Buděšínský, Miloš, Mitrová, Katarína, Jiráček, Jiří

Source: ChemPlusChem. 85(6):1297-1306

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107449716.0x000001&indx=1&recIds=ETOCvdc_100107449716.0x000001

The final walk with preptin.

Authors: Mrázková, Lucie, Lubos, Marta, Voldřich, Jan, Kužmová, Erika, Zrubecká, Denisa, Gwozdiaková, Petra, Buděšínský, Miloš, Asai, Seiya, Marek, Aleš, Pícha, Jan, Tencerová, Michaela, Ferenčáková, Michaela, Barrera, Glenda Alquicer, Kaminský, Jakub, Jiráček, Jiří, Žáková, Lenka

Source: PLoS ONE; 9/12/2024, Vol. 19 Issue 9, p1-22, 22p

Subject Terms: INSULIN regulation, BIOLOGICAL systems, METABOLIC regulation, BONE metabolism, PEPTIDES

A versatile insulin analog with high potency for both insulin and insulin-like growth factor 1 receptors: Structural implications for receptor binding

Authors: Chrudinová, Martina, Žáková, Lenka, Marek, Aleš, Socha, Ondřej, Buděšínský, Miloš, Hubálek, Martin, Pícha, Jan, Macháčková, Kateřina, Jiráček, Jiří, Selicharová, Irena

Source: In Journal of Biological Chemistry 26 October 2018 293(43):16818-16829

Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules

Alternate Title: Structural forms of storage insulin in pancreas (English)

Authors: Palivec, Vladimír, Viola, Cristina M., Kozak, Mateusz, Ganderton, Timothy R., Křížková, Květoslava, Turkenburg, Johan P., Haluŝková, Petra, Žáková, Lenka, Jiráĉek, Jiří, Jungwirth, Pavel, Brzozowski, Andrzej M.

Source: In Journal of Biological Chemistry May 2017 292(20):8342-8355

Combinatorial Libraries of Bipodal Binders of the Insulin Receptor.

Authors: Selicharová, Irena, Fabre, Benjamin, Soledad Garre Hernández, María, Lubos, Marta, Pícha, Jan, Voburka, Zdeněk, Mitrová, Katarína, Jiráček, Jiří

Source: ChemMedChem; 6/3/2024, Vol. 19 Issue 11, p1-12, 12p

RXP 407, a Phosphinic Peptide, Is a Potent Inhibitor of Angiotensin I Converting Enzyme Able to Differentiate between Its Two Active Sites

Authors: Dive, Vincent, Cotton, Joël, Yiotakis, Athanasios, Michaud, Annie, Vassiliou, Stamatia, Jiracek, Jiri, Vazeux, Gilles, Chauvet, Marie-Thérèse, Cuniasse, Philippe, Corvol, Pierre

Source: Proceedings of the National Academy of Sciences of the United States of America, 1999 Apr . 96(8), 4330-4335.

Access URL: https://www.jstor.org/stable/47566

Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain

Authors: Hexnerová, Rozálie, Křížková, Květoslava, Fábry, Milan, Sieglová, Irena, Kedrová, Kateřina, Collinsová, Michaela, Ullrichová, Pavlína, Srb, Pavel, Williams, Christopher ^**, Crump, Matthew P. ^**, Tošner, Zdeněk, Jiráček, Jiří, Veverka, Václav, Žáková, Lenka

Source: In Journal of Biological Chemistry September 2016 291(40):21234-21245

Insulin–Dendrimer Nanocomplex for Multi‐Day Glucose‐Responsive Therapy in Mice and Swine.

Authors: Xian, Sijie, Xiang, Yuanhui, Liu, Dongping, Fan, Bowen, Mitrová, Katarína, Ollier, Rachel C., Su, Bo, Alloosh, Muhammad Ali, Jiráček, Jiří, Sturek, Michael, Alloosh, Mouhamad, Webber, Matthew J.

Source: Advanced Materials; Feb2024, Vol. 36 Issue 5, p1-11, 11p

Mono-N-acyl-2,6-diaminopimelic acid derivatives: Analysis by electromigration and spectroscopic methods and examination of enzyme inhibitory activity

Authors: Hlaváček, Jan, Vítovcová, Miloslava, Sázelová, Petra, Pícha, Jan, Vaněk, Václav, Buděšínský, Miloš, Jiráček, Jiří, Gillner, Danuta M., Holz, Richard C., Mikšík, Ivan, Kašička, Václav

Source: In Analytical Biochemistry 15 December 2014 467:4-13

Chapter Six - Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2

Authors: Jiráček, Jiří ^*, Selicharová, Irena, Žáková, Lenka

Source: In Vitamins & Hormones 2023 123:187-230