Benchmarking and integrating human B-cell receptor genomic and antibody proteomic profiling

Authors: Khang Lê Quý, Maria Chernigovskaya, Maria Stensland, Sachin Singh, Jinwoo Leem, Santiago Revale, David A. Yadin, Francesca L. Nice, Chelsea Povall, Danielle H. Minns, Jacob D. Galson, Tuula A. Nyman, Igor Snapkow, Victor Greiff

Source: npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-16 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2056-7189

Access URL: https://doaj.org/article/aed0071f46f041c39749007a85dae5bf

Structural modeling of antibody variable regions using deep learning—progress and perspectives on drug discovery

Authors: Igor Jaszczyszyn, Weronika Bielska, Tomasz Gawlowski, Pawel Dudzic, Tadeusz Satława, Jarosław Kończak, Wiktoria Wilman, Bartosz Janusz, Sonia Wróbel, Dawid Chomicz, Jacob D. Galson, Jinwoo Leem, Sebastian Kelm, Konrad Krawczyk

Source: Frontiers in Molecular Biosciences, Vol 10 (2023)

Subject Terms: deep learning, structural modeling, drug discovery, antibody therapeutics, antibody structure prediction, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2023.1214424/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/b9bf830784aa46f6b4415c0e2d6b8f50

Comparative Analysis of the CDR Loops of Antigen Receptors

Authors: Wing Ki Wong, Jinwoo Leem, Charlotte M. Deane

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: T-cell receptors, antibodies, loop conformations, protein structure prediction, NGS, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.02454/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/2c072af038c2472ca1b62025d38a3e75

Structurally Mapping Antibody Repertoires

Authors: Konrad Krawczyk, Sebastian Kelm, Aleksandr Kovaltsuk, Jacob D. Galson, Dominic Kelly, Johannes Trück, Cristian Regep, Jinwoo Leem, Wing K. Wong, Jaroslaw Nowak, James Snowden, Michael Wright, Laura Starkie, Anthony Scott-Tucker, Jiye Shi, Charlotte M. Deane

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: antibody specificity, B-cell receptor, next-generation sequencing, structural homology, protein, bioinformatics tools, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2018.01698/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/47fb86b0ffff496db413cd8995409a66

Ten simple rules for surviving an interdisciplinary PhD.

Authors: Samuel Demharter, Nicholas Pearce, Kylie Beattie, Isabel Frost, Jinwoo Leem, Alistair Martin, Robert Oppenheimer, Cristian Regep, Tammo Rukat, Alexander Skates, Nicola Trendel, David J Gavaghan, Charlotte M Deane, Bernhard Knapp

Source: PLoS Computational Biology, Vol 13, Iss 5, p e1005512 (2017)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

Access URL: https://doaj.org/article/87aff83779474d909af97ab2ff6a0cca