Automated cytometric gating with human-level performance using bivariate segmentation

Authors: Jiong Chen, Matei Ionita, Yanbo Feng, Yinfeng Lu, Patryk Orzechowski, Sumita Garai, Kenneth Hassinger, Jingxuan Bao, Junhao Wen, Duy Duong-Tran, Joost Wagenaar, Michelle L. McKeague, Mark M. Painter, Divij Mathew, Ajinkya Pattekar, Nuala J. Meyer, E. John Wherry, Allison R. Greenplate, Li Shen

Source: Nature Communications, Vol 16, Iss 1, Pp 1-15 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/c3fd7cc39cb247c9bdc3cb9c33b7f8b6

Genetic and clinical correlates of two neuroanatomical AI dimensions in the Alzheimer’s disease continuum

Authors: Junhao Wen, Zhijian Yang, Ilya M. Nasrallah, Yuhan Cui, Guray Erus, Dhivya Srinivasan, Ahmed Abdulkadir, Elizabeth Mamourian, Gyujoon Hwang, Ashish Singh, Mark Bergman, Jingxuan Bao, Erdem Varol, Zhen Zhou, Aleix Boquet-Pujadas, Jiong Chen, Arthur W. Toga, Andrew J. Saykin, Timothy J. Hohman, Paul M. Thompson, Sylvia Villeneuve, Randy Gollub, Aristeidis Sotiras, Katharina Wittfeld, Hans J. Grabe, Duygu Tosun, Murat Bilgel, Yang An, Daniel S. Marcus, Pamela LaMontagne, Tammie L. Benzinger, Susan R. Heckbert, Thomas R. Austin, Lenore J. Launer, Mark Espeland, Colin L. Masters, Paul Maruff, Jurgen Fripp, Sterling C. Johnson, John C. Morris, Marilyn S. Albert, R. Nick Bryan, Susan M. Resnick, Luigi Ferrucci, Yong Fan, Mohamad Habes, David Wolk, Li Shen, Haochang Shou, Christos Davatzikos

Source: Translational Psychiatry, Vol 14, Iss 1, Pp 1-14 (2024)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://doaj.org/toc/2158-3188

Access URL: https://doaj.org/article/56d631e8319148739bce0f8e8b35d005

Statistical Evaluation of Effect of Shape Imperfections on Buckling Load of Carbon Fiber-Reinforced Plastic Thin-Walled Cylinders

Authors: Jingxuan Bao, Atsushi Takano, Ryuta Kitamura, Takuma Masai

Source: Applied Sciences, Vol 15, Iss 4, p 2094 (2025)

Subject Terms: buckling, thin-walled cylinders, knockdown factor, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3417/15/4/2094; https://doaj.org/toc/2076-3417

Access URL: https://doaj.org/article/37e23d2070184e2eb7026bf10f8a102f

The genetic architecture of multimodal human brain age

Authors: Junhao Wen, Bingxin Zhao, Zhijian Yang, Guray Erus, Ioanna Skampardoni, Elizabeth Mamourian, Yuhan Cui, Gyujoon Hwang, Jingxuan Bao, Aleix Boquet-Pujadas, Zhen Zhou, Yogasudha Veturi, Marylyn D. Ritchie, Haochang Shou, Paul M. Thompson, Li Shen, Arthur W. Toga, Christos Davatzikos

Source: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0b986bda725642da9bd3943d43862752

Gene-SGAN: discovering disease subtypes with imaging and genetic signatures via multi-view weakly-supervised deep clustering

Authors: Zhijian Yang, Junhao Wen, Ahmed Abdulkadir, Yuhan Cui, Guray Erus, Elizabeth Mamourian, Randa Melhem, Dhivya Srinivasan, Sindhuja T. Govindarajan, Jiong Chen, Mohamad Habes, Colin L. Masters, Paul Maruff, Jurgen Fripp, Luigi Ferrucci, Marilyn S. Albert, Sterling C. Johnson, John C. Morris, Pamela LaMontagne, Daniel S. Marcus, Tammie L. S. Benzinger, David A. Wolk, Li Shen, Jingxuan Bao, Susan M. Resnick, Haochang Shou, Ilya M. Nasrallah, Christos Davatzikos

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/e4408877453444c49479a4dba3887d8a

A Principled Framework to Assess the Information-Theoretic Fitness of Brain Functional Sub-Circuits

Authors: Duy Duong-Tran, Nghi Nguyen, Shizhuo Mu, Jiong Chen, Jingxuan Bao, Frederick H. Xu, Sumita Garai, Jose Cadena-Pico, Alan David Kaplan, Tianlong Chen, Yize Zhao, Li Shen, Joaquín Goñi

Source: Mathematics, Vol 12, Iss 19, p 2967 (2024)

Subject Terms: brain connectomics, functional networks, stochastic block model, individualized parcellation, Mathematics, QA1-939

File Description: electronic resource

Relation: https://www.mdpi.com/2227-7390/12/19/2967; https://doaj.org/toc/2227-7390

Access URL: https://doaj.org/article/d876363623f847cebdf3c340f3893d1f

Brain-wide genome-wide colocalization study for integrating genetics, transcriptomics and brain morphometry in Alzheimer's disease

Authors: Jingxuan Bao, Junhao Wen, Zixuan Wen, Shu Yang, Yuhan Cui, Zhijian Yang, Guray Erus, Andrew J. Saykin, Qi Long, Christos Davatzikos, Li Shen

Source: NeuroImage, Vol 280, Iss , Pp 120346- (2023)

Subject Terms: Alzheimer's disease, Imaging-genetics, Multi-modality, Colocalization, Mediation analysis, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1053811923004974; https://doaj.org/toc/1095-9572

Access URL: https://doaj.org/article/a1c9974470b342f383526495380eba11

An interpretable Alzheimer’s disease oligogenic risk score informed by neuroimaging biomarkers improves risk prediction and stratification

Authors: Erica H. Suh, Garam Lee, Sang-Hyuk Jung, Zixuan Wen, Jingxuan Bao, Kwangsik Nho, Heng Huang, Christos Davatzikos, Andrew J. Saykin, Paul M. Thompson, Li Shen, Dokyoon Kim, for the Alzheimer’s Disease Neuroimaging Initiative

Source: Frontiers in Aging Neuroscience, Vol 15 (2023)

Subject Terms: polygenic risk score, Alzheimer’s disease, mild cognitive impairment, genetics, predictive markers, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnagi.2023.1281748/full; https://doaj.org/toc/1663-4365

Access URL: https://doaj.org/article/709ece1d1b2b4951b0a5e18e5d9f08ca

Identifying genes associated with brain volumetric differences through tissue specific transcriptomic inference from GWAS summary data

Authors: Hung Mai, Jingxuan Bao, Paul M. Thompson, Dokyoon Kim, Li Shen

Source: BMC Bioinformatics, Vol 23, Iss S3, Pp 1-13 (2022)

Subject Terms: Genetic variation, Gene expression, Brain imaging, Imaging genomic association, Brain volume, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2105

Access URL: https://doaj.org/article/053695b5b074403e9f63beacf13dfe24

Homological Landscape of Human Brain Functional Sub-Circuits

Authors: Duy Duong-Tran, Ralph Kaufmann, Jiong Chen, Xuan Wang, Sumita Garai, Frederick H. Xu, Jingxuan Bao, Enrico Amico, Alan D. Kaplan, Giovanni Petri, Joaquin Goni, Yize Zhao, Li Shen

Source: Mathematics, Vol 12, Iss 3, p 455 (2024)

Subject Terms: functional sub-circuit, functional networks, homological kernel, topological data analysis, Mathematics, QA1-939

File Description: electronic resource

Relation: https://www.mdpi.com/2227-7390/12/3/455; https://doaj.org/toc/2227-7390

Access URL: https://doaj.org/article/25a914340ab04742adde15cef79ce56c

Identifying Alzheimer’s genes via brain transcriptome mapping

Authors: Jae Young Baik, Mansu Kim, Jingxuan Bao, Qi Long, Li Shen, Alzheimer’s Disease Neuroimaging Initiative

Source: BMC Medical Genomics, Vol 15, Iss S2, Pp 1-11 (2022)

Subject Terms: Brain imaging transcriptomics, Imaging-diagnosis map, Gene expression map, Internal medicine, RC31-1245, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1755-8794

Access URL: https://doaj.org/article/9b19b4ad417548069066a675fde755dc

Buckling Test of Composite Cylindrical Shells with Large Radius Thickness Ratio

Authors: Atsushi Takano, Ryuta Kitamura, Takuma Masai, Jingxuan Bao

Source: Applied Sciences, Vol 11, Iss 2, p 854 (2021)

Subject Terms: buckling, shell, knockdown factor, Technology, Engineering (General). Civil engineering (General), TA1-2040, Biology (General), QH301-705.5, Physics, QC1-999, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3417/11/2/854; https://doaj.org/toc/2076-3417

Access URL: https://doaj.org/article/ee9c44b6695f4197a6de796eb876231a

Genomic loci influence patterns of structural covariance in the human brain.

Authors: Junhao Wen, Nasrallah, Ilya M., Abdulkadir, Ahmed, Satterthwaite, Theodore D., Zhijian Yang, Erus, Guray, Robert-Fitzgerald, Timothy, Singh, Ashish, Sotiras, Aristeidis, Boquet-Pujadas, Aleix, Mamourian, Elizabeth, Jimit Doshi, Yuhan Cui, Srinivasan, Dhivya, Skampardoni, Ioanna, Jiong Chen, Gyujoon Hwang, Bergman, Mark, Jingxuan Bao, Veturi, Yogasudha

Source: Proceedings of the National Academy of Sciences of the United States of America; 12/26/2023, Vol. 120 Issue 52, p1-12, 43p

Subject Terms: SIZE of brain, SUPPORT vector machines, LOCUS (Genetics), PATHOGENESIS, BRAIN diseases

An interpretable Alzheimer's disease oligogenic risk score informed by neuroimaging biomarkers improves risk prediction and stratification.

Authors: Suh, Erica H., Garam Lee, Sang-Hyuk Jung, Zixuan Wen, Jingxuan Bao, Kwangsik Nho, Heng Huang, Davatzikos, Christos, Saykin, Andrew J., Thompson, Paul M., Li Shen, Dokyoon Kim

Source: Frontiers in Aging Neuroscience; 2023, p1-13, 13p

Subject Terms: GENETICS of Alzheimer's disease, ALZHEIMER'S disease risk factors, BRAIN, BIOMARKERS, MILD cognitive impairment, SINGLE nucleotide polymorphisms, COGNITION, RISK assessment, GENOME-wide association studies, RESEARCH funding, POSITRON emission tomography, RADIOPHARMACEUTICALS, DESCRIPTIVE statistics, GENE expression profiling, PREDICTION models, DEOXY sugars, RECEIVER operating characteristic curves, LOGISTIC regression analysis, NEURORADIOLOGY, PHENOTYPES

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