Just a SNP away: The future of in vivo massively parallel reporter assay

Authors: Katherine N. Degner, Jessica L. Bell, Sean D. Jones, Hyejung Won

Source: Cell Insight, Vol 4, Iss 1, Pp 100214- (2025)

Subject Terms: MPRA, In vivo, Systemic, Noncoding genome, Psychiatric, Neurodevelopmental, Biology (General), QH301-705.5, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772892724000695; https://doaj.org/toc/2772-8927

Access URL: https://doaj.org/article/df2db8cc4fc24182b335aa2682388f71

Copper chelation suppresses epithelial-mesenchymal transition by inhibition of canonical and non-canonical TGF-β signaling pathways in cancer

Authors: Ensieh M. Poursani, Daniele Mercatelli, Prahlad Raninga, Jessica L. Bell, Federica Saletta, Felix V. Kohane, Daniel P. Neumann, Ye Zheng, Jourdin R. C. Rouaen, Toni Rose Jue, Filip T. Michniewicz, Piper Schadel, Erin Kasiou, Maria Tsoli, Giuseppe Cirillo, Shafagh Waters, Tyler Shai-Hee, Riccardo Cazzoli, Merryn Brettle, Iveta Slapetova, Maria Kasherman, Renee Whan, Fernando Souza-Fonseca-Guimaraes, Linda Vahdat, David Ziegler, John G. Lock, Federico M. Giorgi, KumKum Khanna, Orazio Vittorio

Source: Cell & Bioscience, Vol 13, Iss 1, Pp 1-19 (2023)

Subject Terms: Cancer, Copper chelation, EMT, Metastasis, TGF-β signaling pathways, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2045-3701

Access URL: https://doaj.org/article/b17391f9a29d4891bcdc6914896812f8

IGF2BP1 induces neuroblastoma via a druggable feedforward loop with MYCN promoting 17q oncogene expression

Authors: Sven Hagemann, Danny Misiak, Jessica L. Bell, Tommy Fuchs, Marcell I. Lederer, Nadine Bley, Monika Hämmerle, Ehab Ghazy, Wolfgang Sippl, Johannes H. Schulte, Stefan Hüttelmaier

Source: Molecular Cancer, Vol 22, Iss 1, Pp 1-23 (2023)

Subject Terms: 17q gain, BIRC5 (survivin), BTYNB, IGF2BP1, Mivebresib, MYCN, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/ca683df65b6941eab6938839b5d6ab26

Systematic investigation of allelic regulatory activity of schizophrenia-associated common variants

Authors: Jessica C. McAfee, Sool Lee, Jiseok Lee, Jessica L. Bell, Oleh Krupa, Jessica Davis, Kimberly Insigne, Marielle L. Bond, Nanxiang Zhao, Alan P. Boyle, Douglas H. Phanstiel, Michael I. Love, Jason L. Stein, W. Brad Ruzicka, Jose Davila-Velderrain, Sriram Kosuri, Hyejung Won

Source: Cell Genomics, Vol 3, Iss 10, Pp 100404- (2023)

Subject Terms: MPRA, schizophrenia, GWAS, non-coding variants, accessibility-by-contact model, variant function, Genetics, QH426-470, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666979X23002185; https://doaj.org/toc/2666-979X

Access URL: https://doaj.org/article/8699b54b8aa149bd9c2642416266fe09

Focus on your locus with a massively parallel reporter assay

Authors: Jessica C. McAfee, Jessica L. Bell, Oleh Krupa, Nana Matoba, Jason L. Stein, Hyejung Won

Source: Journal of Neurodevelopmental Disorders, Vol 14, Iss 1, Pp 1-14 (2022)

Subject Terms: MPRA, GWAS, Neurodevelopmental disorders, Noncoding genome, Gene regulation, Functional validation, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://doaj.org/toc/1866-1947; https://doaj.org/toc/1866-1955

Access URL: https://doaj.org/article/bf83b58147614695826af08b10a9044c

Q1291H-CFTR molecular dynamics simulations and ex vivo theratyping in nasal epithelial models and clinical response to elexacaftor/tezacaftor/ivacaftor in a Q1291H/F508del patient

Authors: Katelin M. Allan, Miro A. Astore, Egi Kardia, Sharon L. Wong, Laura K. Fawcett, Jessica L. Bell, Simone Visser, Po-Chia Chen, Renate Griffith, Adam Jaffe, Sheila Sivam, Orazio Vittorio, Serdar Kuyucak, Shafagh A. Waters

Source: Frontiers in Molecular Biosciences, Vol 10 (2023)

Subject Terms: cystic fibrosis, CFTR, modulators, airway epithelial cell models, personalized medicine, molecular dynamics, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2023.1148501/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/983bc3fd05834594ba1500ce3059b03f

In vivo tumour imaging employing regional delivery of novel gallium radiolabelled polymer composites

Authors: Ross W. Stephens, Gregory D. Tredwell, Jessica L. Bell, Karen J. Knox, Lee A. Philip, Tim J. Senden, Michael J. Tapner, Stephanie A. Bickley, Marcel R. Tanudji, Stephen K. Jones

Source: Biomaterials Research, Vol 25, Iss 1, Pp 1-9 (2021)

Subject Terms: Vascular particle delivery, Tumour plexus, Tumour imaging, Radiolabelled polymer microspheres, Rabbit tumour model, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2055-7124

Access URL: https://doaj.org/article/6604bce6ff884428b4aa04740f8ffd1a

JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma

Authors: Matthew Wong, Yuting Sun, Zhichao Xi, Giorgio Milazzo, Rebecca C. Poulos, Christoph Bartenhagen, Jessica L. Bell, Chelsea Mayoh, Nicholas Ho, Andrew E. Tee, Xiaoqiong Chen, Yang Li, Roberto Ciaccio, Pei Y. Liu, Chen C. Jiang, Qing Lan, Nisitha Jayatilleke, Belamy B. Cheung, Michelle Haber, Murray D. Norris, Xu D. Zhang, Glenn M. Marshall, Jenny Y. Wang, Stefan Hüttelmaier, Matthias Fischer, Jason W. H. Wong, Hongxi Xu, Giovanni Perini, Qihan Dong, Rani E. George, Tao Liu

Source: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a673d07528164588b51a22500785ed47

Editorial: Ubiquitin-Modifying Enzymes as Drug Targets and Biomarkers in Cancer

Authors: Jessica L. Bell, Alena Malyukova, Jean B. Bertoldo, Matthew K. Summers, Yi Sun

Source: Frontiers in Oncology, Vol 11 (2021)

Subject Terms: ubiquitin, E3 ligase, cancer, proteasome, DUB, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.758983/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/03fa24bc1d764caf926296ade6c595f1

The MicroRNA Landscape of MYCN-Amplified Neuroblastoma

Authors: Danny Misiak, Sven Hagemann, Jessica L. Bell, Bianca Busch, Marcell Lederer, Nadine Bley, Johannes H. Schulte, Stefan Hüttelmaier

Source: Frontiers in Oncology, Vol 11 (2021)

Subject Terms: microRNAs, MYCN, IGF2BP1, mir-17-92 cluster, diagnostic marker, neuroblastoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.647737/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/9e16d521f31e40e880ef13446d59b3db

Design and synthesis of tag-free photoprobes for the identification of the molecular target for CCG-1423, a novel inhibitor of the Rho/MKL1/SRF signaling pathway

Authors: Jessica L. Bell, Andrew J. Haak, Susan M. Wade, Yihan Sun, Richard R. Neubig, Scott D. Larsen

Source: Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 966-973 (2013)

Subject Terms: CCG-1423, click ligation, photoaffinity labeling, Rho pathway inhibitor, tag-free photoprobe, target identification, Science, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://doaj.org/toc/1860-5397

Access URL: https://doaj.org/article/1410c15613b14136b7c7e0dde49221a5

Ex Vivo Oculomotor Slice Culture from Embryonic GFP-Expressing Mice for Time-Lapse Imaging of Oculomotor Nerve Outgrowth

Authors: Mary C. Whitman, author^{1, 2, 3}, Jessica L. Bell, author^{1, 3}, Elaine H. Nguyen, author^{1, 3}, Elizabeth C. Engle, author^{1, 2, 3, 4, 5, 6}

Source: Journal of Visualized Experiments. (149)

Availability: http://www.jove.com/video/59911

TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members.

Authors: Jessica L Bell, Alena Malyukova, Jessica K Holien, Jessica Koach, Michael W Parker, Maria Kavallaris, Glenn M Marshall, Belamy B Cheung

Source: PLoS ONE, Vol 7, Iss 5, p e37470 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22629402/pdf/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/b159544ce93a4517aecfb916f003a6c6