Study protocol of the METAPANC trial - intensified treatment in patients with local operable but oligometastatic pancreatic cancer - multimodal surgical treatment versus chemotherapy alone: a randomized controlled trial

Authors: Michael Ghadimi, Uwe Pelzer, Marc G. Besselink, Jens Siveke, Ralph Telgmann, Rickmer Braren, Hanneke Wilmink, Marie Crede, Alexander Koenig, Ute Koenig, Sven Thorsten Liffers, Kai Antweiler, Bas Uijterwijk, Hanna Seppanen, Arno Nordin, Pauli Puolakkainen, Olav F. Dajani, Knut Jørgen Labori, Mia Johansson, Svein Olav Bratlie, Tim Friede, Peter Jo

Source: BMC Cancer, Vol 25, Iss 1, Pp 1-12 (2025)

Subject Terms: Oligometastasis, Pancreatic ductal carcinoma (PDAC), Oligometastatic pancreatic cancer, Liver metastasis, Multimodal treatment, Chemotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/d5d766bd0b564ed9927e21bb8a6e31ad

Protocol of the IntenSify‐Trial: An open‐label phase I trial of the CYP3A inhibitor cobicistat and the cytostatics gemcitabine and nab‐paclitaxel in patients with advanced stage or metastatic pancreatic ductal adenocarcinoma to evaluate the combination's pharmacokinetics, safety, and efficacy

Authors: Nicolas Hohmann, Martin Ronald Sprick, Moritz Pohl, Azaz Ahmed, Jürgen Burhenne, Marietta Kirchner, Lucian Le Cornet, Markus Kratzmann, Jacek Hajda, Albrecht Stenzinger, Karen Steindorf, Stefan Delorme, Heinz‐Peter Schlemmer, Sabine Riethdorf, Ron vanSchaik, Klaus Pantel, Jens Siveke, Thomas Seufferlein, Dirk Jäger, Walter E. Haefeli, Andreas Trumpp, Christoph Springfeld

Source: Clinical and Translational Science, Vol 16, Iss 12, Pp 2483-2493 (2023)

Subject Terms: Therapeutics. Pharmacology, RM1-950, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1752-8054; https://doaj.org/toc/1752-8062

Access URL: https://doaj.org/article/c68c01273a54478990c71f106d610b42

1294 External validation of machine learning models to predict efficacy and toxicity of immune checkpoint inhibitors using real-world pan cancer cohorts

Authors: Jens Siveke, Alexander Roesch, Viktor Grünwald, Zoltan Kiss, Jan Wolber, Martin Schuler, Julius Keyl, Levente Lippenszky, Pablo Napan-Molina, Eszter Csernai, Travis Osterman, Balazs Laczi, Alexander Brehmer, Moon Kim, Moritz Meyer, Stefan Kasper, Jens Kleesiek

Source: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/3a6634d240ae47788e4dfdf6be8081b6

[18F]FDG PET/MRI enables early chemotherapy response prediction in pancreatic ductal adenocarcinoma

Authors: Felix N. Harder, Friederike Jungmann, Georgios A. Kaissis, Fabian K. Lohöfer, Sebastian Ziegelmayer, Daniel Havel, Michael Quante, Maximillian Reichert, Roland M. Schmid, Ihsan Ekin Demir, Helmut Friess, Moritz Wildgruber, Jens Siveke, Alexander Muckenhuber, Katja Steiger, Wilko Weichert, Isabel Rauscher, Matthias Eiber, Marcus R. Makowski, Rickmer F. Braren

Source: EJNMMI Research, Vol 11, Iss 1, Pp 1-11 (2021)

Subject Terms: PDAC, PET/MRI, Chemotherapy, Response prediction, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: https://doaj.org/toc/2191-219X

Access URL: https://doaj.org/article/9c170cfcd8144ea083e9ae9c00ecb409

Hyperpolarized 13C pyruvate magnetic resonance spectroscopy for in vivo metabolic phenotyping of rat HCC

Authors: Elisabeth Bliemsrieder, Georgios Kaissis, Martin Grashei, Geoffrey Topping, Jennifer Altomonte, Christian Hundshammer, Fabian Lohöfer, Irina Heid, Dominik Keim, Selamawit Gebrekidan, Marija Trajkovic-Arsic, Aline Winkelkotte, Katja Steiger, Roman Nawroth, Jens Siveke, Markus Schwaiger, Marcus Makowski, Franz Schilling, Rickmer Braren

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/e0a491a41dc04952be5b8e9b40040ec7

A machine learning model for the prediction of survival and tumor subtype in pancreatic ductal adenocarcinoma from preoperative diffusion-weighted imaging

Authors: Georgios Kaissis, Sebastian Ziegelmayer, Fabian Lohöfer, Hana Algül, Matthias Eiber, Wilko Weichert, Roland Schmid, Helmut Friess, Ernst Rummeny, Donna Ankerst, Jens Siveke, Rickmer Braren

Source: European Radiology Experimental, Vol 3, Iss 1, Pp 1-9 (2019)

Subject Terms: Machine learning, Diffusion magnetic resonance imaging, Pancreatic carcinoma, Radiomics, Survival analysis, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s41747-019-0119-0; https://doaj.org/toc/2509-9280

Access URL: https://doaj.org/article/d7a868f772a24161b5c328977cae37ee

Epigenetics of gastrointestinal diseases: notes from a workshop

Authors: David L. Marks, Rachel L. Olson, Raul Urrutia, Daniel D. Billadeau, Nilotpal Roy, George A. Calin, Muller Fabbri, Marina Koutsioumpa, Dimitrios Iliopoulos, Tamas Ordog, Robert Huebert, Olga Sarmento, Adebowale O. Bamidele, William Faubion, Gwen L. Lomberk, Jens Siveke, Nita Ahuja, Juan Iovanna, Ryan A. Hlady, Keith Robertson, John Kisiel, Christopher L. Pin, Martin E. Fernandez-Zapico

Source: Epigenetics, Vol 13, Iss 4, Pp 449-457 (2018)

Subject Terms: gastrointestinal diseases, epigenetics, chromatin, mirna, dna methylation, biomarkers, therapeutics, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1559-2294; https://doaj.org/toc/1559-2308

Access URL: https://doaj.org/article/23e86de7b3ef46bbaca872d31226b0f5

Community-driven development of a modified progression-free survival ratio for precision oncology

Authors: Sebastian Schölch, Benedikt Brors, Albrecht Stenzinger, Ursula Ehmer, Ulrich-Frank Pape, Christoph Springfeld, Dirk Jäger, Felix J Hüttner, Andreas Mock, Christoph E Heilig, Simon Kreutzfeldt, Daniel Huebschmann, Christoph Heining, Evelin Schröck, Richard Schlenk, Hanno Glimm, Stefan Fröhling, Peter Horak, Leonidas Apostolidis, Marinela Augustin, Daniela Aust, Irfan Ahmed Bhatti, Johannes Bloehdorn, Cornelia Brendel, Christian Britschgi, Jan Braess, Stefan Burdach, Elena Busch, Jozefina Casuscelli, Alexander Desuki, Thomas Deutsch, Mareike Dietrich, Thomas J Ettrich, Johanna Falkenhorst, Tanja Fehm, Anne Flörcken, Andrea Forschner, Stefan Fuxius, Maria Gonzales-Carmona, Frank Griesinger, Sabine Grill, Stefan Gröschel, Georg Martin Haag, Ulrich Haag, Niels Halama, Holger Hebart, Nina Heidger, Barbara Hermes, Georg Hess, Simone Hettmer, Manuela Hoechstetter, Martin Hoffmann, Anna L Illert, Maximilian Jenzer, Bernd Kasper, Stefan Kasper-Virchow, Thomas Kindler, Ewa Koscielniak, Jan Krönke, Michael Kühn, Volker Kunzmann, Alois Lang, Jonas Leichsenring, Elisabeth Livingstone, Lucia Liotta, Kim Luley, Elisabeth Mack, Uwe M Martens, Klaus Metzeler, Jan Moritz Middeke, Lino Möhrmann, Roopa Jayarama-Naidu, Lukas Perkhofer, Arne Pfeufer, Constantin Pixberg, Michael Quante, Bernhard Rendenbach, Damian Rieke, Christian Rothermundt, Andre Norbert Sagerer, Martin Salzmann, Dieter Saur, Bastian Schilling, Jan Schleicher, Anke Schlenska-Lange, Thomas Schmidt, Sophia Schmitz, Rajiv Shah, Khalid Shoumariyeh, Alexander Siebenhüner, Martin Singh, Jens Siveke, Helen Starke, Sophia Strobel, Veronica Teleanu, Niklas Thon, Sebastian Wagner, Thomas Walle, Benedikt Westphalen, Bettina Whitlock, Eva Winkler, Naita Maren Wirsik, Lena Woydack, Angelika Zabel-du Bois, Stefanie Zschäbitz

Source: ESMO Open, Vol 4, Iss 6 (2019)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://esmoopen.bmj.com/content/4/6/e000583.full; https://doaj.org/toc/2059-7029

Access URL: https://doaj.org/article/0122f1ac148444cbaeb951db5af876a5

Author Correction: Hyperpolarized 13C pyruvate magnetic resonance spectroscopy for in vivo metabolic phenotyping of rat HCC

Authors: Elisabeth Bliemsrieder, Georgios Kaissis, Martin Grashei, Geoffrey Topping, Jennifer Altomonte, Christian Hundshammer, Fabian Lohöfer, Irina Heid, Dominik Keim, Selamawit Gebrekidan, Marija Trajkovic-Arsic, AM Winkelkotte, Katja Steiger, Roman Nawroth, Jens Siveke, Markus Schwaiger, Marcus Makowski, Franz Schilling, Rickmer Braren

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/ef4a7a702fa94f6ebd05fc4931519cda

Integrin-Targeted Hybrid Fluorescence Molecular Tomography/X-ray Computed Tomography for Imaging Tumor Progression and Early Response in Non-Small Cell Lung Cancer

Authors: Xiaopeng Ma, Valerie Phi Van, Melanie A. Kimm, Jaya Prakash, Horst Kessler, Katja Kosanke, Annette Feuchtinger, Michaela Aichler, Aayush Gupta, Ernst J. Rummeny, Michel Eisenblätter, Jens Siveke, Axel K. Walch, Rickmer Braren, Vasilis Ntziachristos, Moritz Wildgruber

Source: Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 1, Pp 8-16 (2017)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S147655861630210X; https://doaj.org/toc/1476-5586; https://doaj.org/toc/1522-8002

Access URL: https://doaj.org/article/cca4c019ff4249e8a2046ea0dbf7d60d

ITOC2 – 006. Notch triggers myeloid reprogramming in murine pancreatic cancer

Authors: Florian, Neff, David, Kirsch G., Dieter, Saur, Roland, Schmid M., Mathias, Heikenwälder F., Jens, Siveke T.

Source: In European Journal of Cancer March 2015 51 Supplement 1:S2-S3

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