Trial watch: anticancer vaccination with dendritic cells

Authors: Francisca Borges, Raquel S. Laureano, Isaure Vanmeerbeek, Jenny Sprooten, Octavie Demeulenaere, Jannes Govaerts, Lisa Kinget, Saurabh Saraswat, Benoit Beuselinck, Steven De Vleeschouwer, Paul Clement, Frederik De Smet, Rüdiger V. Sorg, Angeliki Datsi, Nathalie Vigneron, Stefan Naulaerts, Abhishek D. Garg

Source: OncoImmunology, Vol 13, Iss 1 (2024)

Subject Terms: Antigen cross-presentation, clinical trial, DAMPs, dendritic cells, immune checkpoint blockers, T cell priming, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/62ea562a7fa84a7596a062de5d9f27c9

Single cell dynamics of tumor specificity vs bystander activity in CD8+ T cells define the diverse immune landscapes in colorectal cancer

Authors: Daniel Morales Borràs, Sara Verbandt, Markus Ausserhofer, Gregor Sturm, Jinyeong Lim, Gil Arasa Verge, Isaure Vanmeerbeek, Raquel S. Laureano, Jannes Govaerts, Jenny Sprooten, Yourae Hong, Rebecca Wall, Gert De Hertogh, Xavier Sagaert, Gabriele Bislenghi, André D’Hoore, Albert Wolthuis, Francesca Finotello, Woong-Yang Park, Stefan Naulaerts, Sabine Tejpar, Abhishek D. Garg

Source: Cell Discovery, Vol 9, Iss 1, Pp 1-30 (2023)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2056-5968

Access URL: https://doaj.org/article/b6bbbd98e72c4ea192406d7073bc5f95

Trial watch: chemotherapy-induced immunogenic cell death in oncology

Authors: Jenny Sprooten, Raquel S. Laureano, Isaure Vanmeerbeek, Jannes Govaerts, Stefan Naulaerts, Daniel M. Borras, Lisa Kinget, Jitka Fucíková, Radek Špíšek, Lenka Palová Jelínková, Oliver Kepp, Guido Kroemer, Dmitri V. Krysko, An Coosemans, Rianne D.W. Vaes, Dirk De Ruysscher, Steven De Vleeschouwer, Els Wauters, Evelien Smits, Sabine Tejpar, Benoit Beuselinck, Sigrid Hatse, Hans Wildiers, Paul M. Clement, Peter Vandenabeele, Laurence Zitvogel, Abhishek D. Garg

Source: OncoImmunology, Vol 12, Iss 1 (2023)

Subject Terms: CAR T cells, antigen-presenting cells, chemotherapy, danger signals, dendritic cell, immune-checkpoint blockers, immunogenic cell death, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/7008e019d7c247f4ac120beabac8edc7

894 Conserved immune inhibitory receptor-signaling in macrophages limits antitumour chemo-immunotherapy

Authors: Sabine Tejpar, Abhishek D Garg, Louis Boon, Massimiliano Mazzone, Jenny Sprooten, Isaure Vanmeerbeek, Stefan Naulaerts, Raquel Salvador, Jannes Govaerts, Rosa Trotta, Samantha Pretto, Shikang Zhao, Sarah Trusso Cafarello, Joren Verelst, Maarten Jacquemyn, Martyna Pociupany, Susan M Schlenner, Dirk Daelemans

Source: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/4d74b171dccc4687ac58e89d21d9fc32

Trial watch: Dendritic cell (DC)-based immunotherapy for cancer

Authors: Raquel S Laureano, Jenny Sprooten, Isaure Vanmeerbeerk, Daniel M Borras, Jannes Govaerts, Stefan Naulaerts, Zwi N Berneman, Benoit Beuselinck, Kalijn F Bol, Jannie Borst, an Coosemans, Angeliki Datsi, Jitka Fučíková, Lisa Kinget, Bart Neyns, Gerty Schreibelt, Evelien Smits, Rüdiger V Sorg, Radek Spisek, Kris Thielemans, Sandra Tuyaerts, Steven De Vleeschouwer, I Jolanda M de Vries, Yanling Xiao, Abhishek D Garg

Source: OncoImmunology, Vol 11, Iss 1 (2022)

Subject Terms: Dendritic cells, DAMPs, TAAs, antigen cross-presentation, T cell priming, immune checkpoint blockers, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/be78d83094d145fe958410723c8c8404

A first-in-class, non-invasive, immunodynamic biomarker approach for precision immuno-oncology

Authors: Jenny Sprooten, An Coosemans, Abhishek D. Garg

Source: OncoImmunology, Vol 11, Iss 1 (2022)

Subject Terms: immunosurveillance, anticancer immunity, inhibitory receptors, lymphocytes, benign or borderline lesions, immunology, neutrophils, wound healing, tgfb1, pattern-recognition receptors (prrs), ovarian canc er, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/73f0cdc9ceb144bcbbfc7fc1c640c633

Peripherally-driven myeloid NFkB and IFN/ISG responses predict malignancy risk, survival, and immunotherapy regime in ovarian cancer

Authors: Antonia Carla Testa, Sabine Tejpar, Ignace Vergote, Valentina Chiappa, An Coosemans, Thaïs Baert, Chiara Landolfo, Wouter Froyman, Dirk Timmerman, Tom Bourne, Abhishek D Garg, Patrizia Agostinis, Louis Boon, Daniela Fischerova, Caroline Van Holsbeke, Jenny Sprooten, Ann Vankerckhoven, Isaure Vanmeerbeek, Daniel M Borras, Yani Berckmans, Roxanne Wouters, Raquel S Laureano, Dominique Schols

Source: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/9/11/e003609.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/c7317b3b6a0e4a03af4f9f35a3b5424c

The Interface of Tumour-Associated Macrophages with Dying Cancer Cells in Immuno-Oncology

Authors: Isaure Vanmeerbeek, Jannes Govaerts, Raquel S. Laureano, Jenny Sprooten, Stefan Naulaerts, Daniel M. Borras, Damya Laoui, Massimiliano Mazzone, Jo A. Van Ginderachter, Abhishek D. Garg

Source: Cells, Vol 11, Iss 23, p 3890 (2022)

Subject Terms: macrophages, cancer therapy, tumour microenvironment, radiotherapy, chemotherapy, immunotherapy, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/23/3890; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/8915dc7290e54dc2a42fb2582c530c49

Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology

Authors: Isaure Vanmeerbeek, Jenny Sprooten, Dirk De Ruysscher, Sabine Tejpar, Peter Vandenberghe, Jitka Fucikova, Radek Spisek, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi, Abhishek D. Garg

Source: OncoImmunology, Vol 9, Iss 1 (2020)

Subject Terms: antigen-presenting cell, autophagy, cytotoxic t lymphocyte, endoplasmic reticulum stress, car t cells, cytokines, chemokines, dendritic cell, immune checkpoint blocker, type i interferon, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/430f227a2bff4708a263f3d1cd73a5de

Trial watch: dendritic cell vaccination for cancer immunotherapy

Authors: Jenny Sprooten, Jolien Ceusters, An Coosemans, Patrizia Agostinis, Steven De Vleeschouwer, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi, Abhishek D. Garg

Source: OncoImmunology, Vol 8, Iss 11 (2019)

Subject Terms: antigen cross-presentation, damps, immune checkpoint blockers, plasmacytoid dendritic cells, tlr signaling, tumor-infiltrating lymphocytes, clinical trial, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/c5ccb54faf214b31843b0797a54eda70

Necroptosis in Immuno-Oncology and Cancer Immunotherapy

Authors: Jenny Sprooten, Pieter De Wijngaert, Isaure Vanmeerbeek, Shaun Martin, Peter Vangheluwe, Susan Schlenner, Dmitri V. Krysko, Jan B. Parys, Geert Bultynck, Peter Vandenabeele, Abhishek D. Garg

Source: Cells, Vol 9, Iss 8, p 1823 (2020)

Subject Terms: cytokines, interferons, danger signals, damage-associated molecular patterns (DAMPs), dendritic cells, macrophages, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/8/1823; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/3c46b3c6e3b34df9987c4428e0f4bcfe