Identification of Potent, Selective, and Metabolically Stable Peptide Antagonists to the Calcitonin Gene-Related Peptide (CGRP) Receptor.

Authors: Les P. Miranda, Jerry Ryan Holder, Licheng Shi, Brian Bennett, Jennifer Aral, Colin V. Gegg, Marie Wright, Kenneth Walker, George Doellgast, Rick Rogers, Hongyan Li, Violeta Valladares, Kevin Salyers, Eileen Johnson, Kenneth Wild

Source: Journal of Medicinal Chemistry; Dec2008, Vol. 51 Issue 24, p7889-7897, 9p

Design and Synthesis of Conformationally Constrained Glucagon-Like Peptide-1 Derivatives with Increased Plasma Stability and Prolonged in Vivo Activity.

Authors: Les P. Miranda, Katherine A. Winters, Colin V. Gegg, Ankita Patel, Jennifer Aral, Jason Long, Jingwen Zhang, Stephanie Diamond, Mark Guido, Shanaka Stanislaus, Mark Ma, Hongyan Li, Mark J. Rose, Leszek Poppe, Murielle M. Véniant

Source: Journal of Medicinal Chemistry; Apr2008, Vol. 51 Issue 9, p2758-2765, 8p