SIV Env RhmAbs + N-803 at ART initiation prolongs viral decay without disrupting reservoir establishment in SIV-infected infant macaques.

Authors: Omotayo Farinre, Tzoalli Anaya, Alexis C King, Kedan Endrias, Anne H Hébert, Alison L Hill, Sherrie Jean, Jennifer S Wood, Stephanie Ehnert, Shan Liang, Gregory M Laird, Rosemarie D Mason, Mario Roederer, Jeffrey T Safrit, Maud Mavigner, Ann Chahroudi

Source: PLoS Pathogens, Vol 21, Iss 1, p e1012863 (2025)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/c096287215a64453a6030bea04794c54

Combinatorial immunotherapy of N-803 (IL-15 superagonist) and dinutuximab with ex vivo expanded natural killer cells significantly enhances in vitro cytotoxicity against GD2+ pediatric solid tumors and in vivo survival of xenografted immunodeficient NSG mice

Authors: Patrick Soon-Shiong, Dean A. Lee, Yaya Chu, Gaurav Nayyar, Jeffrey T Safrit, Susiyan Jiang, Jeremy M. Rosenblum, Mitchell S. Cairo

Source: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/9/7/e002267.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/88879cd3923d4e4d9638289ac32ef8a0

Novel cytokine–antibody fusion protein, N-820, to enhance the functions of ex vivo expanded natural killer cells against Burkitt lymphoma

Authors: John Lee, Dean Lee, Patrick Soon-Shiong, Yaya Chu, Gaurav Nayyar, Nang Kham Su, Jeremy M Rosenblum, Jeffrey T Safrit, Matthew Barth, Mitchell S Cairo

Source: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/8/2/e001238.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/752d96bf91744f83a32d2522239e2b10

The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques.

Authors: Gabriela M Webb, Jhomary Molden, Kathleen Busman-Sahay, Shaheed Abdulhaqq, Helen L Wu, Whitney C Weber, Katherine B Bateman, Jason S Reed, Mina Northrup, Nicholas Maier, Shiho Tanaka, Lina Gao, Brianna Davey, Benjamin L Carpenter, Michael K Axthelm, Jeffrey J Stanton, Jeremy Smedley, Justin M Greene, Jeffrey T Safrit, Jacob D Estes, Pamela J Skinner, Jonah B Sacha

Source: PLoS Pathogens, Vol 16, Iss 3, p e1008339 (2020)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/01a8e5f9eca0493ca269580027d9bf0e

Conventional early infant diagnosis in Lesotho from specimen collection to results usage to manage patients: Where are the bottlenecks?

Authors: Appolinaire Tiam, Michelle M Gill, Heather J Hoffman, Anthony Isavwa, Mafusi Mokone, Matokelo Foso, Jeffrey T Safrit, Lynne M Mofenson, Thorkild Tylleskär, Laura Guay

Source: PLoS ONE, Vol 12, Iss 10, p e0184769 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5634554?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ee5730b0b474469ca18c51d1dfb1bb7c

HIV monoclonal antibodies: a new opportunity to further reduce mother-to-child HIV transmission.

Authors: Yegor Voronin, Lynne M Mofenson, Coleen K Cunningham, Mary G Fowler, Pontiano Kaleebu, Elizabeth J McFarland, Jeffrey T Safrit, Barney S Graham, William Snow

Source: PLoS Medicine, Vol 11, Iss 4, p e1001616 (2014)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1001616&type=printable; https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

Access URL: https://doaj.org/article/e2ad87ef41a54bf1908efa2bb54decf9

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Biotech's role in advancing HIV vaccine development

Authors: Roger Tatoud, Christian Brander, Carey Hwang, Jo Kennelly, Shan Lu, Kevin O’Neil, Jeffrey T. Safrit, Iris Benhayoun, Julieta Firmat, Nelli Barriere

Source: Emerging Microbes and Infections, Vol 13, Iss 1 (2024)

Subject Terms: HIV, HIV vaccine, research and development, biotech, pharmaceutical industry, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/1e868e7013ca4c5d9df6436e086114c7

Intranasal plus subcutaneous prime vaccination with a dual antigen COVID-19 vaccine elicits T-cell and antibody responses in mice

Authors: Adrian Rice, Mohit Verma, Annie Shin, Lise Zakin, Peter Sieling, Shiho Tanaka, Joseph Balint, Kyle Dinkins, Helty Adisetiyo, Brett Morimoto, Wendy Higashide, C. Anders Olson, Shivani Mody, Patricia Spilman, Elizabeth Gabitzsch, Jeffrey T. Safrit, Shahrooz Rabizadeh, Kayvan Niazi, Patrick Soon-Shiong

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/c2a806620483477893a8b28004af78a6

Heterologous saRNA Prime, DNA Dual-Antigen Boost SARS-CoV-2 Vaccination Elicits Robust Cellular Immunogenicity and Cross-Variant Neutralizing Antibodies

Authors: Adrian Rice, Mohit Verma, Emily Voigt, Peter Battisti, Sam Beaver, Sierra Reed, Kyle Dinkins, Shivani Mody, Lise Zakin, Shiho Tanaka, Brett Morimoto, C. Anders Olson, Elizabeth Gabitzsch, Jeffrey T. Safrit, Patricia Spilman, Corey Casper, Patrick Soon-Shiong

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: self-amplifying RNA, DNA, vaccine, dual antigen, heterologous, spike, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.910136/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/dc6ab025ea6648e8bf50a56a033d58df

Dual-Antigen COVID-19 Vaccine Subcutaneous Prime Delivery With Oral Boosts Protects NHP Against SARS-CoV-2 Challenge

Authors: Elizabeth Gabitzsch, Jeffrey T. Safrit, Mohit Verma, Adrian Rice, Peter Sieling, Lise Zakin, Annie Shin, Brett Morimoto, Helty Adisetiyo, Raymond Wong, Ashish Bezawada, Kyle Dinkins, Joseph Balint, Victor Peykov, Hermes Garban, Philip Liu, Andrew Bacon, Pete Bone, Jeff Drew, Daniel C. Sanford, Patricia Spilman, Lennie Sender, Shahrooz Rabizadeh, Kayvan Niazi, Patrick Soon-Shiong

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: non-human primate (NHP), vaccine, dual antigen, COVID-19, SARS-CoV-2 challenge, protection, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.729837/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/eaca2f9f97bc467580412ac134a60533