HSP60 controls mitochondrial ATP generation for optimal virus-specific IL-21-producing CD4 and cytotoxic CD8 memory T cell responses

Authors: Nazanin Ghahari, Saina Shegefti, Mahsa Alaei, Amine Amara, Roman Telittchenko, Stéphane Isnard, Jean-Pierre Routy, David Olagnier, Julien van Grevenynghe

Source: Communications Biology, Vol 7, Iss 1, Pp 1-19 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/0c88e662a4f24abd9e3c783ac2106239

Corrigendum to 'Vaccination after developing long COVID: Impact on clinical presentation, viral persistence and immune responses' [International Journal of Infectious Diseases, volume 136 (2023), 136–145, doi:10.1016/j.ijid.2023.09.006]

Authors: Maryam Nayyerabadi, Lyvia Fourcade, Swarali A. Joshi, Prabha Chandrasekaran, Arpita Chakravarti, Chantal Massé, Marie-Lorna Paul, Joanie Houle, Amina M. Boubekeur, Charlotte DuSablon, Valérie Boudreau, Danijela Bovan, Emma Darbinian, Emilia Aïsha Coleman, Sandra Vinci, Jean-Pierre Routy, Pierre-Olivier Hétu, Johanne Poudrier, Emilia Liana Falcone

Source: International Journal of Infectious Diseases, Vol 153, Iss , Pp 107842- (2025)

Subject Terms: Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1201971225000657; https://doaj.org/toc/1201-9712

Access URL: https://doaj.org/article/1dc3c0ce80c741d991e4c3ef63fbecd6

Anti-PD-L1 antibody ASC22 in combination with a histone deacetylase inhibitor chidamide as a 'shock and kill' strategy for ART-free virological control: a phase II single-arm study

Authors: Luling Wu, Zhihang Zheng, Jingna Xun, Li Liu, Jiangrong Wang, Xinyu Zhang, Yueming Shao, Yinzhong Shen, Renfang Zhang, Min Zhang, Meiyan Sun, Tangkai Qi, Zhenyan Wang, Shuibao Xu, Wei Song, Yang Tang, Bihe Zhao, Zichen Song, Jean-Pierre Routy, Hongzhou Lu, Jun Chen

Source: Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-11 (2024)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/842e488f954247f1a02a9c89c283bae1

Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity

Authors: Stephane Isnard, Tsoarello Mabanga, Léna Royston, Carolina A. Berini, Simeng Bu, Orthy Aiyana, Hansen Feng, Bertrand Lebouché, Cecilia T. Costiniuk, Joseph Cox, Guido Kroemer, Madeleine Durand, Jean-Pierre Routy, the Biobanque Québécoise de la COVID-19 (BQC-19)

Source: Frontiers in Immunology, Vol 15 (2025)

Subject Terms: Acyl-CoA-binding protein, autophagy, COVID-19, SARS-CoV-2, proteomics, BQC-19 biobank, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1505752/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3fb3c0413f92465182de4f38c9ba528a

Patient-reported outcomes and experiences of migrants enrolled in a multidisciplinary HIV clinic with rapid, free, and onsite treatment dispensation: the ‘ASAP’ study

Authors: Anish K. Arora, Serge Vicente, Kim Engler, David Lessard, Edmundo Huerta, Joel Ishak, Nadine Kronfli, Jean-Pierre Routy, Joseph Cox, Benoit Lemire, Marina Klein, Alexandra de Pokomandy, Lina Del Balso, Giada Sebastiani, Isabelle Vedel, Amélie Quesnel-Vallée, Bertrand Lebouché, ASAP Migrant Advisory Committee

Source: AIDS Research and Therapy, Vol 21, Iss 1, Pp 1-13 (2024)

Subject Terms: Migrants, HIV, Patient-reported outcomes, Care experience, Multidisciplinary, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1742-6405

Access URL: https://doaj.org/article/ee4b34e3011845129d52702400ea36ef

Opposite Roles of IL-32α Versus IL-32β/γ Isoforms in Promoting Monocyte-Derived Osteoblast/Osteoclast Differentiation and Vascular Calcification in People with HIV

Authors: Hardik Ramani, Aurélie Cleret-Buhot, Mohamed Sylla, Rémi Bunet, Florent Bertrand, Marc-Messier Peet, Carl Chartrand-Lefebvre, Benoit Trottier, Réjean Thomas, Jean-Pierre Routy, Claude Fortin, Valérie Martel-Laferrière, Manel Sadouni, Guy Cloutier, Louise Allard, Jorge R. Kizer, Nicolas Chomont, Petronela Ancuta, David B. Hanna, Robert C. Kaplan, Mohammad-Ali Jenabian, Alan L. Landay, Madeleine Durand, Mohamed El-Far, Cécile L. Tremblay

Source: Cells, Vol 14, Iss 7, p 481 (2025)

Subject Terms: HIV, inflammation, IL-32, cardiovascular diseases, arterial calcification, atherosclerosis, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/14/7/481; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/40677e237e9245b59500251b27c1a226

The value of a PET scan in selecting the best lymph node to biopsy, and confirming the diagnosis of idiopathic multicentric Castleman disease with HLH and EBV viremia in a previously healthy adult

Authors: Erica Bitektine, Hamila Hagh-Daoust, René P. Michel, Stephane Isnard, Jean-Pierre Routy

Source: European Journal of Case Reports in Internal Medicine (2024)

Subject Terms: lymphoproliferative disorders, multicentric castleman disease, epstein-barr virus, siltuximab, interleukin-6, Medicine

File Description: electronic resource

Relation: https://www.ejcrim.com/index.php/EJCRIM/article/view/4908; https://doaj.org/toc/2284-2594

Access URL: https://doaj.org/article/72814000926b4d17a4595542ff436be3

Metformin facilitates viral reservoir reactivation and their recognition by anti-HIV-1 envelope antibodies

Authors: Augustine Fert, Jonathan Richard, Laurence Raymond Marchand, Delphine Planas, Jean-Pierre Routy, Nicolas Chomont, Andrés Finzi, Petronela Ancuta

Source: iScience, Vol 27, Iss 9, Pp 110670- (2024)

Subject Terms: Medication, Virology, Molecular microbiology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004224018959; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/f0e7023e3226433cba971be540ffd895

Altered memory CCR6+ Th17-polarised T-cell function and biology in people with HIV under successful antiretroviral therapy and HIV elite controllersResearch in context

Authors: Alexis Yero, Jean-Philippe Goulet, Tao Shi, Cecilia T. Costiniuk, Jean-Pierre Routy, Cecile Tremblay, Ralph-Sydney Mboumba Bouassa, Yulia Alexandrova, Amélie Pagliuzza, Nicolas Chomont, Petronela Ancuta, Mohammad-Ali Jenabian

Source: EBioMedicine, Vol 107, Iss , Pp 105274- (2024)

Subject Terms: Th17 cells, CCR6, HIV infection, Transcriptomics, HIV persistence, DNA damage, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396424003104; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/ca111586e7a54db389f6a611caef3faa

Excess BAFF May Impact HIV-1-Specific Antibodies and May Promote Polyclonal Responses Including Those from First-Line Marginal Zone B-Cell Populations

Authors: Kim Doyon-Laliberté, Matheus Aranguren, Josiane Chagnon-Choquet, Laurie-Anne Batraville, Olina Dagher, Jonathan Richard, Matteo Paniconi, Jean-Pierre Routy, Cécile Tremblay, Marie-Claude Quintal, Nathalie Brassard, Daniel E. Kaufmann, Andrés Finzi, Johanne Poudrier, Michel Roger

Source: Current Issues in Molecular Biology, Vol 46, Iss 1, Pp 25-43 (2023)

Subject Terms: BAFF, HIV-1, B-cells, marginal zone, antibodies, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1467-3045/46/1/3; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Access URL: https://doaj.org/article/c20c0e25dc9b4e00a5969e51c9f62b7e

Vaccination after developing long COVID: Impact on clinical presentation, viral persistence, and immune responses

Authors: Maryam Nayyerabadi, Lyvia Fourcade, Swarali A. Joshi, Prabha Chandrasekaran, Arpita Chakravarti, Chantal Massé, Marie-Lorna Paul, Joanie Houle, Amina M. Boubekeur, Charlotte DuSablon, Valérie Boudreau, Danijela Bovan, Emma Darbinian, Emilia Aïsha Coleman, Sandra Vinci, Jean-Pierre Routy, Pierre-Olivier Hétu, Johanne Poudrier, Emilia Liana Falcone

Source: International Journal of Infectious Diseases, Vol 136, Iss , Pp 136-145 (2023)

Subject Terms: Post-COVID-19 conditions (PCC), Long COVID, Post-acute sequelae of COVID-19 (PASC), Vaccination, Inflammation, Viral persistence, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1201971223007208; https://doaj.org/toc/1201-9712

Access URL: https://doaj.org/article/d74a1183418047bc9d8073d80f5b4e86

Preventative behaviours and COVID-19 infection in a Canadian cohort of people living with HIV

Authors: Keely Hammond, Terry Lee, Branka Vulesevic, Joel Singer, Judy Needham, Ann N. Burchell, Hasina Samji, Sharon Walmsley, Mark Hull, Mohammad-Ali Jenabian, Jean-Pierre Routy, Shari Margolese, Enrico Mandarino, Aslam H. Anis, Curtis L. Cooper, Cecilia T. Costiniuk

Source: AIDS Research and Therapy, Vol 20, Iss 1, Pp 1-10 (2023)

Subject Terms: COVID-19 preventative behaviours, Masking, Physical distancing, People living with HIV, COVID-19 immunization, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1742-6405

Access URL: https://doaj.org/article/22d50c8f76f04c72a59203eae546e3d0

Double-Negative T-Cells during Acute Human Immunodeficiency Virus and Simian Immunodeficiency Virus Infections and Following Early Antiretroviral Therapy Initiation

Authors: Alexis Yero, Tao Shi, Julien A. Clain, Ouafa Zghidi-Abouzid, Gina Racine, Cecilia T. Costiniuk, Jean-Pierre Routy, Jérôme Estaquier, Mohammad-Ali Jenabian

Source: Viruses, Vol 16, Iss 10, p 1609 (2024)

Subject Terms: CD4−CD8− T-cells, double negative (DN) T-cells, acute SIV infection, acute HIV infection, early ART, regulatory T-cells (Tregs), Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/16/10/1609; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/ae57dd0368cc415c972bb1891580decd

Effects of statins beyond lipid-lowering agents in ART-treated HIV infection

Authors: Vikram Mehraj, Jun Chen, Jean-Pierre Routy

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: statins, HIV, cardiovascular diseases, inflammation, immune activation, REPRIEVE randomized clinical trial, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1339338/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/c50c17e266334c88bd692fccd5af56c8

Proteomics validate circulating GDF-15 as an independent biomarker for COVID-19 severity

Authors: Simeng Bu, Léna Royston, Tsoarello Mabanga, Carolina A. Berini, Cécile Tremblay, Bertrand Lebouché, Joseph Cox, Cecilia T. Costiniuk, Madeleine Durand, Stephane Isnard, Jean-Pierre Routy

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: GDF-15, COVID-19, SARS-CoV-2, proteomics, BQC19, severity, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1377126/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/118497c2a4684df6a727941e2a1e3d08

Haemophagocytic lymphohistiocytosis following the anti-PD-1 nivolumab in a patient with gastric cancer and ankylosing spondylitis

Authors: Clara Long, Abdulrahman Al-Abdulmalek, Jonathan Lai, David G. Haegert, Stephane Isnard, Denis Cournoyer, Jean-Pierre Routy

Source: European Journal of Case Reports in Internal Medicine (2024)

Subject Terms: hemophagocytic lymphohistiocytosis, immunotherapy, anti-pd1, gastric cancer, ankylosing spondylitis, Medicine

File Description: electronic resource

Relation: https://www.ejcrim.com/index.php/EJCRIM/article/view/4370; https://doaj.org/toc/2284-2594

Access URL: https://doaj.org/article/462c6f2c25e1487f94983410b51227c1

Translocation of bacterial LPS is associated with self-reported cognitive abilities in men living with HIV receiving antiretroviral therapy

Authors: Stéphane Isnard, Léna Royston, Susan C. Scott, Tsoarello Mabanga, John Lin, Brandon Fombuena, Simeng Bu, Carolina A. Berini, Mark S. Goldberg, Malcolm Finkelman, Marie-Josée Brouillette, Lesley K. Fellows, Nancy E. Mayo, Jean-Pierre Routy

Source: AIDS Research and Therapy, Vol 20, Iss 1, Pp 1-10 (2023)

Subject Terms: People living with HIV, Cognition, Gut, Microbial translocation, LPS, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1742-6405

Access URL: https://doaj.org/article/b97515952f954b30a725d9e7d90c361e

Self-tests for COVID-19: What is the evidence? A living systematic review and meta-analysis (2020–2023)

Authors: Apoorva Anand, Fiorella Vialard, Aliasgar Esmail, Faiz Ahmad Khan, Patrick O’Byrne, Jean-Pierre Routy, Keertan Dheda, Nitika Pant Pai

Source: PLOS Global Public Health, Vol 4, Iss 2 (2024)

Subject Terms: Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10849237/?tool=EBI; https://doaj.org/toc/2767-3375

Access URL: https://doaj.org/article/799e4dc792f94d36940ebbdaffddc4df

Candida albicans can foster gut dysbiosis and systemic inflammation during HIV infection

Authors: Silvere D Zaongo, Jing Ouyang, Stéphane Isnard, Xin Zhou, Vijay Harypursat, Hongjuan Cui, Jean-Pierre Routy, Yaokai Chen

Source: Gut Microbes, Vol 15, Iss 1 (2023)

Subject Terms: Candida albicans, HIV, gut microbiota, dysbiosis, systemic infections, microbial translocation, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/83d5dc948c40450dba6988787aaad1bc

Phylogenetic Network Analyses Reveal the Influence of Transmission Clustering on the Spread of HIV Drug Resistance in Quebec from 2002 to 2022

Authors: Bluma G. Brenner, Ruxandra-Ilinca Ibanescu, Maureen Oliveira, Guillaume Margaillan, Bertrand Lebouché, Réjean Thomas, Jean Guy Baril, René-Pierre Lorgeoux, Michel Roger, Jean-Pierre Routy, the Montreal Primary HIV Infection (PHI) Cohort Study Group

Source: Viruses, Vol 16, Iss 8, p 1230 (2024)

Subject Terms: HIV-1, acquired and transmitted drug resistance, antiretroviral therapy, phylogenetic clustering, M184V, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4915/16/8/1230; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/9df76998881d47ff9fb4f08985ef4684