Targeting mTOR in myeloid cells prevents infection-associated inflammation

Authors: Yohana C. Toner, Jazz Munitz, Geoffrey Prevot, Judit Morla-Folch, William Wang, Yuri van Elsas, Bram Priem, Jeroen Deckers, Tom Anbergen, Thijs J. Beldman, Eliane E.S. Brechbühl, Muhammed D. Aksu, Athanasios Ziogas, Sebastian A. Sarlea, Mumin Ozturk, Zhenhua Zhang, Wenchao Li, Yang Li, Alexander Maier, Jessica C. Fernandes, Glenn A.O. Cremers, Bas van Genabeek, Joost H.C.M. Kreijtz, Esther Lutgens, Niels P. Riksen, Henk M. Janssen, Serge H.M. Söntjens, Freek J.M. Hoeben, Ewelina Kluza, Gagandeep Singh, Evangelos J. Giamarellos-Bourboulis, Michael Schotsaert, Raphaël Duivenvoorden, Roy van der Meel, Leo A.B. Joosten, Lei Cai, Ryan E. Temel, Zahi A. Fayad, Musa M. Mhlanga, Mandy M.T. van Leent, Abraham J.P. Teunissen, Mihai G. Netea, Willem J.M. Mulder

Source: iScience, Vol 28, Iss 4, Pp 112163- (2025)

Subject Terms: Natural sciences, Biological sciences, Biochemistry, Immunology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004225004249; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/42ac9256a7534f0d84459dcca42fb410

Systematically evaluating DOTATATE and FDG as PET immuno-imaging tracers of cardiovascular inflammation

Authors: Yohana C. Toner, Adam A. Ghotbi, Sonum Naidu, Ken Sakurai, Mandy M. T. van Leent, Stefan Jordan, Farideh Ordikhani, Letizia Amadori, Alexandros Marios Sofias, Elizabeth L. Fisher, Alexander Maier, Nathaniel Sullivan, Jazz Munitz, Max L. Senders, Christian Mason, Thomas Reiner, Georgios Soultanidis, Jason M. Tarkin, James H. F. Rudd, Chiara Giannarelli, Jordi Ochando, Carlos Pérez-Medina, Andreas Kjaer, Willem J. M. Mulder, Zahi A. Fayad, Claudia Calcagno

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/fa3ab96dbfaf460a95866d8ed9e9732b

FSH-blocking therapeutic for osteoporosis

Authors: Sakshi Gera, Tan-Chun Kuo, Anisa Azatovna Gumerova, Funda Korkmaz, Damini Sant, Victoria DeMambro, Karthyayani Sudha, Ashley Padilla, Geoffrey Prevot, Jazz Munitz, Abraham Teunissen, Mandy MT van Leent, Tomas GJM Post, Jessica C Fernandes, Jessica Netto, Farhath Sultana, Eleanor Shelly, Satish Rojekar, Pushkar Kumar, Liam Cullen, Jiya Chatterjee, Anusha Pallapati, Sari Miyashita, Hasni Kannangara, Megha Bhongade, Puja Sengupta, Kseniia Ievleva, Valeriia Muradova, Rogerio Batista, Cemre Robinson, Anne Macdonald, Susan Hutchison, Mansi Saxena, Marcia Meseck, John Caminis, Jameel Iqbal, Maria I New, Vitaly Ryu, Se-Min Kim, Jay J Cao, Neeha Zaidi, Zahi A Fayad, Daria Lizneva, Clifford J Rosen, Tony Yuen, Mone Zaidi

Source: eLife, Vol 11 (2022)

Subject Terms: PK/PD, ADME, aging, monoclonal antibody, pituitary hormone, menopause, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/78022; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/0b0425ac3b2842fcad3a4a75380448c1

Employing nanobodies for immune landscape profiling by PET imaging in mice

Authors: Abraham J.P. Teunissen, Omar B. Abousaway, Jazz Munitz, Mandy M.T. van Leent, Yohana C. Toner, Bram Priem, Max L. Senders, Carlos Pérez-Medina, Willem J.M. Mulder, Mohammad Rashidian

Source: STAR Protocols, Vol 2, Iss 2, Pp 100434- (2021)

Subject Terms: Antibody, Immunology, Model Organisms, Molecular Biology, Molecular/Chemical Probes, Science (General), Q1-390

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666166721001416; https://doaj.org/toc/2666-1667

Access URL: https://doaj.org/article/00dfd0086d3e4a29a7cf9e9072741d87