Mapping MAGE-A4 expression in solid cancers for targeted therapies

Authors: Christin Habigt, Sylvie Rottey, Iben Spanggaard, Juanita S. Lopez, Elena Garralda, Emiliano Calvo, Oliver Bechter, Jayesh Desai, Rachel Galot, Leena Gandhi, Florian Heil, Natascha Rieder, Ivan Dimitrov, Iris Martinez Quetglas, Christian Heichinger, Nino Keshelava, Andreas Roller

Source: Frontiers in Oncology, Vol 15 (2025)

Subject Terms: biomarker, translational analysis, clinical trial, target expression, patient selection, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2025.1484182/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/b27fe0d2c45a4c8997c746a18fcf9b6f

A signal-seeking phase 2 study of Trastuzumab emtansine in tumours harbouring HER2 amplification or mutation

Authors: Subotheni Thavaneswaran, Frank Lin, John P. Grady, David Espinoza, Min Li Huang, Sarah Chinchen, Lucille Sebastian, Maya Kansara, Tony Mersiades, Chee Khoon Lee, Jayesh Desai, Peter Grimison, Michael Brown, Michael Millward, Rosemary Harrup, Ken O’Byrne, Adnan Nagrial, Paul Craft, John Simes, Anthony M. Joshua, David M. Thomas

Source: npj Precision Oncology, Vol 8, Iss 1, Pp 1-10 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2397-768X

Access URL: https://doaj.org/article/56a6cbd28f68431a92cbd65b7b352b9c

Effects of clinical and socioeconomic factors on Medicare and patient costs for colorectal cancer in Australia: a retrospective multivariate regression analysis

Authors: Sallie-Anne Pearson, Peter Gibbs, David Roder, Jayesh Desai, Fanny Franchini, Marliese Alexander, Yuting Zhang, Adam Elshaug, David Attwood, Stephen Fox, Sean Grimmond, Ou Yang, Yat Hang To, Maarten M J IJzerman, Judith Liu, Karen Trapani, Koen Degeling, Grant McArthur Ben Solomon, Sophy Athan, Paul Baden, Wendy Benson, Catherine Bressanutti, George Jiang, Carolyn Rowan

Source: BMJ Open, Vol 14, Iss 12 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/14/12/e081483.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/a6cf35fd7df34a859d3620c25ae609aa

BCL-XL inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAF V600E colorectal cancer

Authors: Laura J. Jenkins, Ian Y. Luk, Fiona Chionh, Tao Tan, Kristen Needham, Jamieson Ayton, Camilla M. Reehorst, Natalia Vukelic, Oliver M. Sieber, Dmitri Mouradov, Peter Gibbs, David S. Williams, Niall C. Tebbutt, Jayesh Desai, Frédéric Hollande, Amardeep S. Dhillon, Erinna F. Lee, Delphine Merino, W. Douglas Fairlie, John M. Mariadason

Source: Cell Death and Disease, Vol 15, Iss 3, Pp 1-9 (2024)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/6e4f88d9b616433e88bdbae69ee002cc

Changing trends in phase 1 oncology clinical trials

Authors: Richard Kelly, Christina Guo, Jayesh Desai, Ben Tran

Source: Contemporary Clinical Trials Communications, Vol 37, Iss , Pp 101239- (2024)

Subject Terms: Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2451865423001850; https://doaj.org/toc/2451-8654

Access URL: https://doaj.org/article/1ccefd4999504a828c6c98564db484e9

Systematic review of NTRK 1/2/3 fusion prevalence pan-cancer and across solid tumours

Authors: Sophie O’Haire, Fanny Franchini, Yoon-Jung Kang, Julia Steinberg, Karen Canfell, Jayesh Desai, Stephen Fox, Maarten IJzerman

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/b35f94e22ce342f6b4dba59d58182fb6

Co-enrichment of CD8-positive T cells and macrophages is associated with clinical benefit of tislelizumab in solid tumors

Authors: Dingwei Ye, Jayesh Desai, Jingwen Shi, Si-Yang Maggie Liu, Wei Shen, Tengfei Liu, Yang Shi, Dan Wang, Liang Liang, Silu Yang, Xiaopeng Ma, Wei Jin, Pei Zhang, Ruiqi Huang, Zhirong Shen, Yun Zhang, Yi-Long Wu

Source: Biomarker Research, Vol 11, Iss 1, Pp 1-12 (2023)

Subject Terms: Immunotherapy, Tumor microenvironment, Macrophages, Immune cells, Tislelizumab, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2050-7771

Access URL: https://doaj.org/article/48b24d1af75c492dafcdc3284ea4b0f0

Mesenchymal chondrosarcoma: An Australian multi‐centre cohort study

Authors: Madeleine C. Strach, Peter S. Grimison, Angela Hong, Richard Boyle, Paul Stalley, Rooshdiya Karim, Elizabeth A. Connolly, Susie Bae, Jayesh Desai, Philip Crowe, Nimit Singhal, Vivek A. Bhadri

Source: Cancer Medicine, Vol 12, Iss 1, Pp 368-378 (2023)

Subject Terms: chemotherapy, mesenchymal chondrosarcoma, prognostic factors, treatment outcome, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/8369783cc437428cb37391415363f5bd

Efficacy and safety of cosibelimab, an anti-PD-L1 antibody, in metastatic cutaneous squamous cell carcinoma

Authors: Jayesh Desai, Stephane Dalle, Jermaine Coward, Daniel Brungs, Andrew Mant, Margaret McGrath, Andrea Tazbirkova, Piotr Koralewski, Iwona Lugowska, Arunee Dechaphunkul, Virote Sriuranpong, James Oliviero, Philip Clingan, Rahul Ladwa, Eva Muñoz-Couselo, Henri Montaudié, Miguel-Ángel Berciano-Guerrero, Dean Laurence Harris, Susan Arnold, Samuel Fourie, Andriy Kurochkin, Daniel R Malan, Vinay Sharma, Hong Shue, Chaiyut Charoentum, Oleksandr Dudnichenko

Source: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/11/10/e007637.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/ba79bd85b8124e27b03c0ee657e71ed1

Hybrid-control arm construction using historical trial data for an early-phase, randomized controlled trial in metastatic colorectal cancer

Authors: Chen Li, Ana Ferro, Shivani K. Mhatre, Danny Lu, Marcus Lawrance, Xiao Li, Shi Li, Simon Allen, Jayesh Desai, Marwan Fakih, Michael Cecchini, Katrina S. Pedersen, Tae You Kim, Irmarie Reyes-Rivera, Neil H. Segal, Christelle Lenain

Source: Communications Medicine, Vol 2, Iss 1, Pp 1-8 (2022)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2730-664X

Access URL: https://doaj.org/article/a2d8a6d7f97440f4b6e89b19aac1153c

Activity of the Gamma Secretase Inhibitor AL101 in Desmoid Tumors: A Case Report of 2 Adult Cases

Authors: David Chan, Jason Kaplan, Gary Gordon, Jayesh Desai

Source: Current Oncology, Vol 28, Iss 5, Pp 3659-3667 (2021)

Subject Terms: aggressive fibromatosis, AL102, BMS-986115, BMS-906024, Notch pathway, rare disease, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.mdpi.com/1718-7729/28/5/312; https://doaj.org/toc/1198-0052; https://doaj.org/toc/1718-7729

Access URL: https://doaj.org/article/2dcd466511624f01829f3727d3ae78b3

Pexidartinib improves physical functioning and stiffness in patients with tenosynovial giant cell tumor: results from the ENLIVEN randomized clinical trial

Authors: Michiel Van De Sande, William D Tap, Heather L Gelhorn, Xin Ye, Rebecca M Speck, Emanuela Palmerini, Silvia Stacchiotti, Jayesh Desai, Andrew J Wagner, Thierry Alcindor, Kristen Ganjoo, Javier Martín-Broto, Qiang Wang, Dale Shuster, Hans Gelderblom, John H Healey

Source: Acta Orthopaedica, Vol 92, Iss 4, Pp 493-499 (2021)

Subject Terms: Orthopedic surgery, RD701-811

File Description: electronic resource

Relation: https://doaj.org/toc/1745-3674; https://doaj.org/toc/1745-3682

Access URL: https://doaj.org/article/7df2d1b97ecc4f04afde34eaa2472648

Criteria-based curation of a therapy-focused compendium to support treatment recommendations in precision oncology

Authors: Frank P. Lin, Subotheni Thavaneswaran, John P. Grady, Mandy Ballinger, Maya Kansara, Samantha R. Oakes, Jayesh Desai, Chee Khoon Lee, John Simes, David M. Thomas

Source: npj Precision Oncology, Vol 5, Iss 1, Pp 1-10 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2397-768X

Access URL: https://doaj.org/article/6a749ceadf654e848f7ee68f6d873817

Cost-effectiveness analysis of imaging surveillance in stage II and III extremity soft tissue sarcoma: an Australian perspective

Authors: Susie Bae, Jonathan Karnon, Glenis Crane, Taryn Bessen, Jayesh Desai, Phillip Crowe, Susan Neuhaus

Source: Cost Effectiveness and Resource Allocation, Vol 18, Iss 1, Pp 1-10 (2020)

Subject Terms: Soft tissue sarcoma, Cost-effectiveness, Imaging surveillance, Disease recurrence, Local recurrence, Distant recurrence, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1478-7547

Access URL: https://doaj.org/article/3c6989d0213042fa819ffe7c988d2298

76 Potential mechanisms of resistance identified through analysis of multiple biomarkers in immune hot non-responders with non-small cell lung cancer (NSCLC) treated with tislelizumab

Authors: Yun Zhang, Wei Tan, Qing Zhou, Jayesh Desai, Juan Zhang, Yi-Long Wu, Sanjeev Deva, Jun Zhao, Xiaopeng Ma, Zhirong Shen, Xikun Wu, Shiangjiin Leaw

Source: Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/f1ce66d695d0408f88a206e615ad37c6

New biomarkers for checkpoint inhibitor therapy

Authors: Jayesh Desai, Nikki Burdett

Source: ESMO Open, Vol 5, Iss Suppl 1 (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://esmoopen.bmj.com/content/5/Suppl_1/e000597.full; https://doaj.org/toc/2059-7029

Access URL: https://doaj.org/article/233235edaeb0473e9d4ca491418a5d87

Phase IA/IB study of single-agent tislelizumab, an investigational anti-PD-1 antibody, in solid tumors

Authors: Yun Zhang, Bhumsuk Keam, Jayesh Desai, Ben Markman, Shahneen Sandhu, Michael Millward, Yoon-Koo Kang, Chia-Chi Lin, Yee Chao, Sanjeev Deva, Jong Seok Lee, Chia-Jui Yen, Michael Jameson, Ming-Mo Hou, Chang-Hsien Lu, Kun-Ming Rau, Kyung-Hun Lee, Lisa Horvath, Michael Friedlander, Andrew Hill, Paula Barlow, Chi-Yuan Wu, Liang Liang, John Wu, Virginia Paton

Source: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/8/1/e000453.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/1f2f609e135d4807be9e954535daa4f0

Therapeutic strategies to remodel immunologically cold tumors

Authors: Minyu Wang, Sen Wang, Jayesh Desai, Joseph A Trapani, Paul J Neeson

Source: Clinical & Translational Immunology, Vol 9, Iss 12, Pp n/a-n/a (2020)

Subject Terms: immune checkpoint inhibitor, tumor microenvironment, immune surveillance and resistance, cold tumor, therapeutic strategy, cancer immunotherapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2050-0068

Access URL: https://doaj.org/article/2dea8cbb86c348f8bf8ac816c4d45a10

CD8+ tumor‐infiltrating lymphocytes within the primary tumor of patients with synchronous de novo metastatic colorectal carcinoma do not track with survival

Authors: Rosemary Millen, Shona Hendry, Vignesh Narasimhan, Rebecca Abbott, Matthew Croxford, Peter Gibbs, Jeanne Tie, Hui‐Li Wong, Ian Jones, Suzanne Kosmider, David Byrne, John Zalcberg, Stephen Fox, Jayesh Desai, Kumar Visvanathan, Robert G Ramsay, Ben Tran

Source: Clinical & Translational Immunology, Vol 9, Iss 7, Pp n/a-n/a (2020)

Subject Terms: advanced metastatic colorectal cancer, PD‐L1, tumor infiltrating lymphocytes, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2050-0068

Access URL: https://doaj.org/article/b19af94bbd8c4e68923ccae799bff469

Rapid two-dimensional Protein-A size exclusion chromatography of monoclonal antibodies for titer and aggregation measurements from harvested cell culture fluid samples

Authors: Zachary D. Dunn, Jayesh Desai, Gabriel M. Leme, Dwight R. Stoll, Douglas D. Richardson

Source: mAbs, Vol 12, Iss 1 (2020)

Subject Terms: Two-dimensional liquid chromatography, protein-A, size exclusion chromatography, aggregation, monoclonal antibody, titer, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

Access URL: https://doaj.org/article/06b9363b187149d795c4f4cf0af26491