Multi-omic latent variable data integration reveals multicellular structure pathways associated with resistance to tuberculin skin test (TST)/interferon gamma release assay (IGRA) conversion in Uganda

Authors: Madison S. Cox, Kimberly A. Dill-McFarland, Jason D. Simmons, Penelope Benchek, Harriet Mayanja-Kizza, W. Henry Boom, Catherine M. Stein, Thomas R. Hawn

Source: BMC Genomics, Vol 26, Iss 1, Pp 1-14 (2025)

Subject Terms: Multi-omics, Genetics, Transcriptomics, Epigenetics, Mycobacterium tuberculosis, MOFA, Biotechnology, TP248.13-248.65, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2164

Access URL: https://doaj.org/article/7702a34388ad44f9b725a3399d74c200

Epigenetic programming of host lipid metabolism associated with resistance to TST/IGRA conversion after exposure to Mycobacterium tuberculosis

Authors: Kimberly A. Dill-McFarland, Jason D. Simmons, Glenna J. Peterson, Felicia K. Nguyen, Monica Campo, Penelope Benchek, Catherine M. Stein, Tomas Vaisar, Harriet Mayanja-Kizza, W. Henry Boom, Thomas R. Hawn

Source: mSystems, Vol 9, Iss 9 (2024)

Subject Terms: Mycobacterium tuberculosis, DNA methylation, chromatin remodeling, interferons, monocytes, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5077

Access URL: https://doaj.org/article/b5310dd7b1304cafaf2e9ec3f37e81f3

Mycobacterium tuberculosis-dependent monocyte expression quantitative trait loci, cytokine production, and TB pathogenesis

Authors: Hyejeong Hong, Kimberly A. Dill-McFarland, Jason D. Simmons, Glenna J. Peterson, Penelope Benchek, Harriet Mayanja-Kizza, W. Henry Boom, Catherine M. Stein, Thomas R. Hawn

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: Mycobacterium tuberculosis, expression quantitative trait loci, monocyte response, proinflammatory cytokine, host-pathogen interactions, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1359178/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/a0aa5ef9a6bd430e8e6bb1cdca54ddd9

Control of Cement Timing, Mineralogy, and Texture on Hydro-chemo-mechanical Coupling from CO2 Injection into Sandstone: A Synthesis

Authors: Zhidi Wu, Jason D. Simmons, Samuel Otu, Alex Rinehart, Andrew Luhmann, Jason Heath, Peter Mozley, Bhaskar S. Majumdar

Source: Energies, Vol 16, Iss 24, p 7949 (2023)

Subject Terms: fluid–rock interaction, Morrow B sandstone, CO2-rich brackish solution, flow-through experiment, creep test, cement diagenesis, Technology

File Description: electronic resource

Relation: https://www.mdpi.com/1996-1073/16/24/7949; https://doaj.org/toc/1996-1073

Access URL: https://doaj.org/article/f2699cdf84734ec28bdaa31c30586eca

Monocyte Transcriptional Responses to Mycobacterium tuberculosis Associate with Resistance to Tuberculin Skin Test and Interferon Gamma Release Assay Conversion

Authors: Jason D. Simmons, Kimberly A. Dill-McFarland, Catherine M. Stein, Phu T. Van, Violet Chihota, Thobani Ntshiqa, Pholo Maenetje, Glenna J. Peterson, Penelope Benchek, Mary Nsereko, Kavindhran Velen, Katherine L. Fielding, Alison D. Grant, Raphael Gottardo, Harriet Mayanja-Kizza, Robert S. Wallis, Gavin Churchyard, W. Henry Boom, Thomas R. Hawn

Source: mSphere, Vol 7, Iss 3 (2022)

Subject Terms: tumor necrosis factor alpha, innate immunity, sequence analysis, RNA, transcriptome, host-pathogen interactions, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5042

Access URL: https://doaj.org/article/252d3100c4d740a68e03d104c295cd58

Differentially expressed transcript isoforms associate with resistance to tuberculin skin test and interferon gamma release assay conversion.

Authors: Jason D Simmons, R Max Segnitz, Kimberly A Dill-McFarland, Catherine M Stein, Glenna J Peterson, Harriet Mayanja-Kizza, W Henry Boom, Thomas R Hawn

Source: PLoS ONE, Vol 18, Iss 4, p e0284498 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0284498&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/18e905409be14fb8b0a6884e0c8d5dbf