LXR Agonist T0901317′s Hepatic Impact Overrules Its Atheroprotective Action in Macrophages, Driving Early Atherogenesis in Chow-Diet-Fed Male Apolipoprotein E Knockout Mice

Authors: Menno Hoekstra, Laura M. de Jong, Rick van der Geest, Lidewij R. de Leeuw, Rani Krisnamurthi, Janine J. Geerling, Miranda Van Eck

Source: Biomolecules, Vol 14, Iss 4, p 429 (2024)

Subject Terms: liver X receptor, atherosclerosis, lipid metabolism, liver, macrophage, cholesterol efflux, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/14/4/429; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/81278c42970048989268f38ff1cfb5fb

Hematopoietic upstream stimulating factor 1 deficiency is associated with increased atherosclerosis susceptibility in LDL receptor knockout mice

Authors: Menno Hoekstra, Baoyan Ren, Pirkka-Pekka Laurila, Reeni B. Hildebrand, Jarkko Soronen, Vanessa Frodermann, Zhuang Li, Mariëtte R. Boon, Janine J. Geerling, Patrick C. N. Rensen, Matti Jauhiainen, Miranda Van Eck

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/17a14d3adad549cc9cc447dc81e3bc71

2-Hydroxypropyl-beta-cyclodextrin Treatment Does Not Induce Atherosclerotic Lesion Regression in Western-Type Diet-Fed Apolipoprotein E Knockout Mice

Authors: Olga S.C. Snip, Menno Hoekstra, Yiheng Zhang, Janine J. Geerling, Miranda Van Eck

Source: Biomolecules, Vol 12, Iss 9, p 1205 (2022)

Subject Terms: cyclodextrin, cholesterol efflux, macrophages, atherosclerosis regression, mouse model, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/12/9/1205; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/26f82ccad1024aa2bcaa767b307d2eb0

Inhibition of the central melanocortin system decreases brown adipose tissue activity[S]

Authors: Sander Kooijman, Mariëtte R. Boon, Edwin T. Parlevliet, Janine J. Geerling, Vera van de Pol, Johannes A. Romijn, Louis M. Havekes, Illiana Meurs, Patrick C.N. Rensen

Source: Journal of Lipid Research, Vol 55, Iss 10, Pp 2022-2032 (2014)

Subject Terms: energy expenditure, liver, triglycerides, very low density lipoprotein, white adipose tissue, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520350069; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/1b0ca6cb4294435fa64980491e7d577b

Sympathetic nervous system control of triglyceride metabolism: novel concepts derived from recent studies

Authors: Janine J. Geerling, Mariëtte R. Boon, Sander Kooijman, Edwin T. Parlevliet, Louis M. Havekes, Johannes A. Romijn, Illiana M. Meurs, Patrick C.N. Rensen

Source: Journal of Lipid Research, Vol 55, Iss 2, Pp 180-189 (2014)

Subject Terms: fatty acids, hypertriglyceridemia, liver, white adipose tissue, brown adipose tissue, hypothalamus, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520350264; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/22c9af50d84f4e3fa91da41d2927932a

Circulating insulin stimulates fatty acid retention in white adipose tissue via KATP channel activation in the central nervous system only in insulin-sensitive mice

Authors: Claudia P. Coomans, Janine J. Geerling, Bruno Guigas, Anita M. van den Hoek, Edwin T. Parlevliet, D. Margriet Ouwens, Hanno Pijl, Peter J. Voshol, Patrick C.N. Rensen, Louis M. Havekes, Johannes A. Romijn

Source: Journal of Lipid Research, Vol 52, Iss 9, Pp 1712-1722 (2011)

Subject Terms: brain, insulin resistance, lipid metabolism, lipoprotein lipase, triglycerides, brown adipose tissue, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520408624; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/e28774ae54384d0baefe6731789094a9

Acute central neuropeptide Y administration increases food intake but does not affect hepatic very low-density lipoprotein (VLDL) production in mice.

Authors: Janine J Geerling, Yanan Wang, Louis M Havekes, Johannes A Romijn, Patrick C N Rensen

Source: PLoS ONE, Vol 8, Iss 2, p e55217 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23460782/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/215a32cd2eed48a0973d876cda6dd1d9

GLP-1 receptor activation inhibits VLDL production and reverses hepatic steatosis by decreasing hepatic lipogenesis in high-fat-fed APOE*3-Leiden mice.

Authors: Edwin T Parlevliet, Yanan Wang, Janine J Geerling, Janny P Schröder-Van der Elst, Kristen Picha, Karyn O'Neil, Vedrana Stojanovic-Susulic, Tatiana Ort, Louis M Havekes, Johannes A Romijn, Hanno Pijl, Patrick C N Rensen

Source: PLoS ONE, Vol 7, Iss 11, p e49152 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23133675/pdf/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/22f65b1129434deb817148c89ddabf95