MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57Kip2 targeting

Authors: Silvia Pomella, Matteo Cassandri, Lucrezia D’Archivio, Antonella Porrazzo, Cristina Cossetti, Doris Phelps, Clara Perrone, Michele Pezzella, Antonella Cardinale, Marco Wachtel, Sara Aloisi, David Milewski, Marta Colletti, Prethish Sreenivas, Zoë S. Walters, Giovanni Barillari, Angela Di Giannatale, Giuseppe Maria Milano, Cristiano De Stefanis, Rita Alaggio, Sonia Rodriguez-Rodriguez, Nadia Carlesso, Christopher R. Vakoc, Enrico Velardi, Beat W. Schafer, Ernesto Guccione, Susanne A. Gatz, Ajla Wasti, Marielle Yohe, Myron Ignatius, Concetta Quintarelli, Janet Shipley, Lucio Miele, Javed Khan, Peter J. Houghton, Francesco Marampon, Berkley E. Gryder, Biagio De Angelis, Franco Locatelli, Rossella Rota

Source: Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/b02d638fdabc4c31acb1630b1acf4c96

Pharmacological EZH2 inhibition combined with retinoic acid treatment promotes differentiation and apoptosis in rhabdomyosarcoma cells

Authors: Eleanor O’Brien, Carmen Tse, Ian Tracy, Ian Reddin, Joanna Selfe, Jane Gibson, William Tapper, Reuben J. Pengelly, Jinhui Gao, Ewa Aladowicz, Gemma Petts, Khin Thway, Sergey Popov, Anna Kelsey, Timothy J. Underwood, Janet Shipley, Zoë S. Walters

Source: Clinical Epigenetics, Vol 15, Iss 1, Pp 1-16 (2023)

Subject Terms: Rhabdomyosarcoma, Differentiation therapy, Epigenetic therapy, EZH2, All-trans retinoic acid, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/b09403c2536c486da89cc39dfaf84132

Genomic landscape of platinum resistant and sensitive testicular cancers

Authors: Chey Loveday, Kevin Litchfield, Paula Z. Proszek, Alex J. Cornish, Flavia Santo, Max Levy, Geoff Macintyre, Amy Holryod, Peter Broderick, Darshna Dudakia, Barbara Benton, Maise Al Bakir, Crispin Hiley, Emily Grist, Charles Swanton, Robert Huddart, Tom Powles, Simon Chowdhury, Janet Shipley, Simon O’Connor, James D. Brenton, Alison Reid, David Gonzalez de Castro, Richard S. Houlston, Clare Turnbull

Source: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/fd830b167ba2414b9bc17a0f92cc02a5

Epigenetic Targets in Synovial Sarcoma: A Mini-Review

Authors: Ryland Hale, Sami Sandakly, Janet Shipley, Zoë Walters

Source: Frontiers in Oncology, Vol 9 (2019)

Subject Terms: synovial sarcoma, SS18-SSX, epigenetics, therapeutic targets, SWI/SNF, PRC1, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fonc.2019.01078/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/ce44ea3ecd8d48da8b467e17ee37a1c1

Activating Mutations and/or Expression Levels of Tyrosine Kinase Receptors GRB7, RAS, and BRAF in Testicular Germ Cell Tumors

Authors: Alan McIntyre, Brenda Summersgill, Hayley E. Spendlove, Robert Huddart, Richard Houlston, Janet Shipley

Source: Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 12, Pp 1047-1052 (2005)

Subject Terms: TGCT, RAS, GRB7, ERBB2, BRAF, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558605800405; https://doaj.org/toc/1476-5586; https://doaj.org/toc/1522-8002

Access URL: https://doaj.org/article/d5a40c49f5624b23adacc60d91117db2

ZNF198-FGFR1 Transforms Ba/F3 Cells to Growth Factor Independence and Results in High Level Tyrosine Phosphorylation of STATS 1 and 5

Authors: Damian Smedley, Asuman Demiroglu, Munah Abdul-Rauf, Carol Heatht, Colin Cooper, Janet Shipley, Nicholas C.P. Cross

Source: Neoplasia: An International Journal for Oncology Research, Vol 1, Iss 4, Pp 349-355 (1999)

Subject Terms: ZNF198, FGFR1, t(8, 13), tyrosine kinase, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558699800268; https://doaj.org/toc/1476-5586; https://doaj.org/toc/1522-8002

Access URL: https://doaj.org/article/8b2aa741b0584f9aa3b351e45cd8875e

Disruption of Imprinted Genes at Chromosome Region 11p15.5 in Paediatric Rhabdomyosarcoma

Authors: John Anderson, Anthony Gordon, Aidan McManus, Janet Shipley, Kathy Pritchard-Jones

Source: Neoplasia: An International Journal for Oncology Research, Vol 1, Iss 4, Pp 340-348 (1999)

Subject Terms: rhabdomyosarcoma, imprinting, H19, insulin-like growth factor 2, p57KIP2, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558699800256; https://doaj.org/toc/1476-5586; https://doaj.org/toc/1522-8002

Access URL: https://doaj.org/article/8aae7749bc2b461aad3375203ad21249

The pattern of genomic gains in salivary gland MALT lymphomas

Authors: Yuanping Zhou, Hongtao Ye, Jose I. Martin-Subero, Stefan Gesk, Rifat Hamoudi, Yong-Jie Lu, Rubin Wang, Janet Shipley, Reiner Siebert, Peter G. Isaacson, Ahmet Dogan, Ming-Qing Du

Source: Haematologica, Vol 92, Iss 7 (2007)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/4507; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/b3f6715bb0ac4f8e878c5af384863efd

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Nascent pre‐rRNA overexpression correlates with an adverse prognosis in alveolar rhabdomyosarcoma.

Authors: Daniel Williamson, Yong‐Jie Lu, Cheng Fang, Kathy Pritchard‐Jones, Janet Shipley

Source: Genes, Chromosomes & Cancer; Sep2006, Vol. 45 Issue 9, p839-845, 7p

Assessment by M-FISH of karyotypic complexity and cytogenetic evolution in bladder cancer in vitro.

Authors: Sarah V. Williams, Jacqui Adams, Jane Coulter, Brenda M. Summersgill, Janet Shipley, Margaret A. Knowles

Source: Genes, Chromosomes & Cancer; Aug2005, Vol. 43 Issue 4, p315-328, 14p

Overexpression of genes on 16q associated with cisplatin resistance of testicular germ cell tumor cell lines.

Authors: Charlotte Wilson, Jinshu Yang, Jon C. Strefford, Brenda Summersgill, Bryan D. Young, Janet Shipley, Tim Oliver, Yong-Jie Lu

Source: Genes, Chromosomes & Cancer; Jun2005, Vol. 43 Issue 2, p211-216, 6p

Mapping of a translocation breakpoint in a Peutz–Jeghers hamartoma to the putative PJS locus at 19q13.4 and mutation analysis of candidate genes in polyp and STK11?negative PJS cases.

Authors: Nicholas Hearle, Anneke Lucassen, Rubin Wang, Wendy Lim, Fiona Ross, Robert Wheeler, Isabella Moore, Janet Shipley, Richard Houlston

Source: Genes, Chromosomes & Cancer; Oct2004, Vol. 41 Issue 2, p163-169, 7p

Expression profiling targeting chromosomes for tumor classification and prediction of clinical behavior.

Authors: Yong-Jie Lu, Daniel Williamson, Rubin Wang, Brenda Summersgill, Sandrine Rodriguez, Simon Rogers, Kathy Pritchard-Jones, Colin Campbell, Janet Shipley

Source: Genes, Chromosomes & Cancer; Nov2003, Vol. 38 Issue 3, p207-214, 8p

Methods in Molecular Biology, Volume 204. Molecular Cytogenetics. Protocols and Applications. Yao-Shan Fan (ed). Humana Press, 2002. No of Pages: 411. ISBN: 1 58829 006 9.

Authors: Janet Shipley

Source: Journal of Pathology; Sep2003, Vol. 201 Issue 1, p168, 1p