Updates on radiotherapy-immunotherapy combinations: Proceedings of 6th annual ImmunoRad conference

Authors: Fabiana Gregucci, Sheila Spada, Mary Helen Barcellos-Hoff, Nina Bhardwaj, Charleen Chan Wah Hak, Alba Fiorentino, Chandan Guha, Monica L. Guzman, Kevin Harrington, Fernanda G. Herrera, Jamie Honeychurch, Theodore Hong, Lorea Iturri, Elisabeth Jaffee, Sana D. Karam, Simon R.V. Knott, Constantinos Koumenis, David Lyden, Ariel E. Marciscano, Alan Melcher, Michele Mondini, Anna Mondino, Zachary S. Morris, Sean Pitroda, Sergio A. Quezada, Laura Santambrogio, Stephen Shiao, John Stagg, Irma Telarovic, Robert Timmerman, Marie-Catherine Vozenin, Ralph Weichselbaum, James Welsh, Anna Wilkins, Chris Xu, Roberta Zappasodi, Weiping Zou, Alexandre Bobard, Sandra Demaria, Lorenzo Galluzzi, Eric Deutsch, Silvia C. Formenti

Source: OncoImmunology, Vol 12, Iss 1 (2023)

Subject Terms: dose and fractionation, FLASH radiotherapy, immune checkpoint inhibitors, immunomodulators, lymph node sparing, tumor-associated macrophages, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/420f3d04260044b482062ca48125b481

Reprogramming the immunosuppressive tumor microenvironment results in successful clearance of tumors resistant to radiation therapy and anti-PD-1/PD-L1

Authors: Debayan Mukherjee, Erminia Romano, Richard Walshaw, Leo A. H. Zeef, Antonia Banyard, Stephen J. Kitcatt, Eleanor J. Cheadle, Karoliina Tuomela, Swati Pendharkar, Aws Al-Deka, Beatrice Salerno, Sophie Raby, Ian G. Mills, Jamie Honeychurch, Tim M. Illidge

Source: OncoImmunology, Vol 12, Iss 1 (2023)

Subject Terms: Radiotherapy, immunotherapy, Tregs, immune Checkpoints, Immunologic diseases. Allergy, RC581-607, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-402X

Access URL: https://doaj.org/article/9f867c6013ac405080b84ec982759eae

Stromal cell inhibition of anti-CD20 antibody mediated killing of B-cell malignancies

Authors: Ester Fagnano, Swati Pendharkar, Madyson Colton, Philip N. Jones, Marta Crespi Sallan, Tetyana Klymenko, Andrejs Braun, Christian Klein, Jamie Honeychurch, Eleanor J. Cheadle, Timothy M. Illidge

Source: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

Subject Terms: CD20, antibody, lymphoma, tumor microenvironment, stroma, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2023.1270398/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/bf6b89e827614726966535cc78f4c00f

The CD40 agonist HERA-CD40L results in enhanced activation of antigen presenting cells, promoting an anti-tumor effect alone and in combination with radiotherapy

Authors: Jamie Frankish, Debayan Mukherjee, Erminia Romano, Katharina Billian-Frey, Matthias Schröder, Karl Heinonen, Christian Merz, Mauricio Redondo Müller, Christian Gieffers, Oliver Hill, Meinolf Thiemann, Jamie Honeychurch, Tim Illidge, Jaromir Sykora

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: CD40, HERA-CD40L, TNFRSF, TRAF2, tumor micro environment (TME), antigen presenting cells, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1160116/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3a2c8f98856e4fc4a7c38804f359c93f

Reprogramming the tumour microenvironment by radiotherapy: implications for radiotherapy and immunotherapy combinations

Authors: Madyson Colton, Eleanor J. Cheadle, Jamie Honeychurch, Tim M. Illidge

Source: Radiation Oncology, Vol 15, Iss 1, Pp 1-11 (2020)

Subject Terms: Radiotherapy, Radiation therapy, Immunotherapy, Immune checkpoints, Immuno-oncology agents, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13014-020-01678-1; https://doaj.org/toc/1748-717X

Access URL: https://doaj.org/article/ce5e0a6e8e0b40d4bae60f86c06ab34f

Evaluation of apoptosis imaging biomarkers in a genetic model of cell death

Authors: Vessela Vassileva, Stephen M. Stribbling, Chris Barnes, Laurence Carroll, Marta Braga, Joel Abrahams, Kathrin Heinzmann, Caroline Haegeman, Marion MacFarlane, Kathryn L. Simpson, Caroline Dive, Jamie Honeychurch, Timothy M. Illidge, Eric O. Aboagye

Source: EJNMMI Research, Vol 9, Iss 1, Pp 1-13 (2019)

Subject Terms: Apoptosis, Caspases, Molecular imaging, 18F-ICMT-11, PET, Radiotracer, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13550-019-0487-8; https://doaj.org/toc/2191-219X

Access URL: https://doaj.org/article/88f942a294f14bd991354aaa6efc2563

The influence of radiation in the context of developing combination immunotherapies in cancer

Authors: Jamie Honeychurch, Timothy M. Illidge

Source: Therapeutic Advances in Vaccines and Immunotherapy, Vol 5 (2017)

Subject Terms: Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2515-1355; https://doaj.org/toc/2515-1363

Access URL: https://doaj.org/article/7a3d76e51a404386a9e66d6561d851c9