De novo donor-specific HLA antibody development after kidney transplantation is impacted by PIRCHE II score and recipient age

Authors: Yuan Tian, Lukas Frischknecht, Fabian Rössler, Thomas Schachtner, Jakob Nilsson

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: kidney transplantation, PIRCHE, donor specific antibodies, virtual cross-match, age, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1508586/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/15301c530e7244918dfd2933198f5092

Self-priming of Plk1 binding to BubR1 ensures accurate mitotic progression

Authors: Chunlin Song, Mingzhe Zhang, Thomas Kruse, Mads Harder Møller, Blanca López-Méndez, Yuqing Zhang, Yujing Zhai, Ying Wang, Tingting Lei, Arminja N. Kettenbach, Jakob Nilsson, Gang Zhang

Source: Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/ece991e00281497d80b9a72cab0b6158

Evaluation of de novo donor specific antibodies after kidney transplantation in the era of donor-derived cell-free DNA

Authors: Yuan Tian, Lukas Frischknecht, Anna Mallone, Fabian Rössler, Thomas Schachtner, Jakob Nilsson

Source: Frontiers in Immunology, Vol 15 (2025)

Subject Terms: kidney transplantation, Dd-cfDNA, donor specific antibodies, DSA, mean fluorescence intensity, MFI, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1530065/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/7afbc8e579cd4218bf4daed6bb3d0351

Assessment of access and outcomes of kidney transplantation through the reforms of the Swiss organ allocation system

Authors: Massimiliano Bertacchi, Sylvie Ferrari-Lacraz, Jakob Nilsson, Agim Thaqi, Yvan Schmutz, Caroline Wehmeier, Thomas Schachtner, Thomas Mueller, Dela Golshayan, Julien Vionnet, Stefan Schaub, Fadi Haidar, Isabelle Binet, Jutta Thierbach, Urs Wirthmueller, Daniel Sidler, Franz Immer, Jean Villard

Source: Frontiers in Public Health, Vol 12 (2025)

Subject Terms: kidney transplantation, allocation system, transplant immunology, allocation fairness, hyperimmunized patients, waiting time, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpubh.2024.1500781/full; https://doaj.org/toc/2296-2565

Access URL: https://doaj.org/article/1390731101214634aa3f42a0ab84fb38

Assessing the Predictive Power of PIRCHE-II Scores for the Development of De Novo Donor-Specific Antibodies After Simultaneous Pancreas-Kidney Transplantation

Authors: Francesca Raineri, Lukas Frischknecht, Jakob Nilsson, Fabian Rössler, Claudia Cavelti-Weder, Seraina von Moos, Thomas Schachtner

Source: Transplant International, Vol 37 (2024)

Subject Terms: simultaneous pancreas and kidney transplant, preformed DSA, de novo DSA, epitope matching, PIRCHE-II score, Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13720/full; https://doaj.org/toc/1432-2277

Access URL: https://doaj.org/article/96ae6df2627542728e9e5bccc0949a89

Proteome-scale characterisation of motif-based interactome rewiring by disease mutations

Authors: Johanna Kliche, Leandro Simonetti, Izabella Krystkowiak, Hanna Kuss, Marcel Diallo, Emma Rask, Jakob Nilsson, Norman E Davey, Ylva Ivarsson

Source: Molecular Systems Biology, Vol 20, Iss 9, Pp 1025-1048 (2024)

Subject Terms: Genetic Variation, Protein–Protein Interaction, Short Linear Motif, Phage Display, CDC45, Biology (General), QH301-705.5, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1744-4292

Access URL: https://doaj.org/article/0bbc2585d8e5430193b425c67f6f3b23

Functional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling

Authors: Yuqing Zhang, Rose Young, Dimitriya H. Garvanska, Chunlin Song, Yujing Zhai, Ying Wang, Hongfei Jiang, Jing Fang, Jakob Nilsson, Claudio Alfieri, Gang Zhang

Source: Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/d09943fe03be43379ae8ecddd544a3e9

HLA class I peptide polymorphisms contribute to class II DQβ0603:DQα0103 antibody specificity

Authors: N. Remi Shih, Thoa Nong, Cathi Murphey, Mayra Lopez-Cepero, Peter W. Nickerson, Jean-luc Taupin, Magali Devriese, Jakob Nilsson, Marie-Benedicte Matignon, Robert A. Bray, Jar-How Lee

Source: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/49d52abf5f4b49deab5278266ec12f7e

VEXAS syndrome: a Swiss national retrospective cohort study

Authors: Louis Wolff, Leo Caratsch, Fabian Lötscher, Luca Seitz, Pascal Seitz, Yann Coattrenec, Jörg Seebach, Oliver Vilinovszki, Stefan Balabanov, Jakob Nilsson, Aylin Canbek, Aurélie Clottu, Rolf Bruecker, Anna Efthymiou, Dena Regli, Manolaraki Chrysoula, Andrea Amstad, Nicola Bonadies, Sabine Blum, Mariana Chitic, Cornelia Schreiber, Denis Comte

Source: Swiss Medical Weekly, Vol 155, Iss 3 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://smw.ch/index.php/smw/article/view/3879; https://doaj.org/toc/1424-3997

Access URL: https://doaj.org/article/941450a60986403aae2799e095f4001c

Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions

Authors: Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson

Source: Molecular Systems Biology, Vol 19, Iss 7, Pp 1-21 (2023)

Subject Terms: clathrin, phage display, phosphomimetic mutation, phosphorylation, protein–protein interactions, Biology (General), QH301-705.5, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1744-4292

Access URL: https://doaj.org/article/48453826b2ae47fd8b34a2bc589dcaef

Biased IL-2 signals induce Foxp3-rich pulmonary lymphoid structures and facilitate long-term lung allograft acceptance in mice

Authors: Yoshito Yamada, Tuan Thanh Nguyen, Daniela Impellizzieri, Katsutaka Mineura, Rintaro Shibuya, Alvaro Gomariz, Martina Haberecker, Jakob Nilsson, César Nombela-Arrieta, Wolfgang Jungraithmayr, Onur Boyman

Source: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/abc4262f8d2243d49d3da3a6fedb78d8

Pre-transplant donor specific antibodies in ABO incompatible kidney transplantation – data from the Swiss transplant cohort study

Authors: Yun Deng, Lukas Frischnknecht, Caroline Wehmeier, Olivier de Rougemont, Jean Villard, Sylvie Ferrari-Lacraz, Déla Golshayan, Monique Gannagé, Isabelle Binet, Urs Wirthmueller, Daniel Sidler, Thomas Schachtner, Stefan Schaub, Jakob Nilsson

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: kidney transplantation, ABO incompatible, donor specific antibodies, ABMR, graft loss, virtual cross-match, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1355128/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/604c4658e9ec41a888d760dfec2d26e4

Detection of donor-derived cell-free DNA in the setting of multiple kidney transplantations

Authors: Linnea Pettersson, Lukas Frischknecht, Sofia Westerling, Hamid Ramezanali, Lukas Weidmann, Kai Castrezana Lopez, Thomas Schachtner, Jakob Nilsson

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: kidney transplantation, donor derived cell free DNA, Dd-cfDNA, ABMR, graft loss, second kidney transplantation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1282521/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/204fc14b26e74941876c575d2fc84288

Phosphatase specificity principles uncovered by MRBLE:Dephos and global substrate identification

Authors: Jamin B Hein, Hieu T Nguyen, Dimitriya H Garvanska, Isha Nasa, Thomas Kruse, Yinnian Feng, Blanca Lopez Mendez, Norman Davey, Arminja N Kettenbach, Polly M Fordyce, Jakob Nilsson

Source: Molecular Systems Biology, Vol 19, Iss 12, Pp n/a-n/a (2023)

Subject Terms: mitotic exit, MRBLE:Dephos, MRBLE‐Pep, protein phosphatase, substrates, Biology (General), QH301-705.5, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1744-4292

Access URL: https://doaj.org/article/2b7f9cdcf70344a5bb703577c2b23118

Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A

Authors: Karolina Pavic, Nikhil Gupta, Judit Domènech Omella, Rita Derua, Anna Aakula, Riikka Huhtaniemi, Juha A. Määttä, Nico Höfflin, Juha Okkeri, Zhizhi Wang, Otto Kauko, Roosa Varjus, Henrik Honkanen, Daniel Abankwa, Maja Köhn, Vesa P. Hytönen, Wenqing Xu, Jakob Nilsson, Rebecca Page, Veerle Janssens, Alexander Leitner, Jukka Westermarck

Source: Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a40d0289287e4365ac202e20daf82ec2

Human SLFN5 and its Xenopus Laevis ortholog regulate entry into mitosis and oocyte meiotic resumption

Authors: Gianmatteo Vit, Alexander Hirth, Nicolas Neugebauer, Bianca N. Kraft, Gianluca Sigismondo, Anna Cazzola, Claudia Tessmer, Joana Duro, Jeroen Krijgsveld, Ilse Hofmann, Michael Berger, Harald Klüter, Christof Niehrs, Jakob Nilsson, Alwin Krämer

Source: Cell Death Discovery, Vol 8, Iss 1, Pp 1-12 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2058-7716

Access URL: https://doaj.org/article/7a6278053c3d445da7d27a233eec76e2

Assessment of treatment response in cardiac sarcoidosis based on myocardial 18F-FDG uptake

Authors: Lukas Frischknecht, Jan Schaab, Eloi Schmauch, Ayla Yalamanoglu, Dennis D. Arnold, Judith Schwaiger, Christiane Gruner, Ronny R. Buechel, Daniel P. Franzen, Antonios G.A. Kolios, Jakob Nilsson

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: cardiac sarcoidosis, myocardial 18F-FDG PET, Anti-TNF, adalimumab, azathioprin, SUVmax, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1286684/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/7ae86f639bca44e3baf9d968ba8602f7

Immunoglobulin signature predicts risk of post-acute COVID-19 syndrome

Authors: Carlo Cervia, Yves Zurbuchen, Patrick Taeschler, Tala Ballouz, Dominik Menges, Sara Hasler, Sarah Adamo, Miro E. Raeber, Esther Bächli, Alain Rudiger, Melina Stüssi-Helbling, Lars C. Huber, Jakob Nilsson, Ulrike Held, Milo A. Puhan, Onur Boyman

Source: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/79cffcd777124d548463576add3f9a75

Donation type and the effect of pre-transplant donor specific antibodies – Data from the Swiss Transplant Cohort Study

Authors: Olivier de Rougemont, Yun Deng, Lukas Frischknecht, Caroline Wehmeier, Jean Villard, Sylvie Ferrari-Lacraz, Déla Golshayan, Monique Gannagé, Isabelle Binet, Urs Wirthmueller, Daniel Sidler, Thomas Schachtner, Stefan Schaub, Jakob Nilsson, the Swiss Transplant Cohort Study, Patrizia Amico, Andres Axel, John David Aubert, Vanessa Banz, Beckmann Sonja, Guido Beldi, Christoph Berger, Ekaterine Berishvili, Pierre-Yves Bochud, Sanda Branca, Heiner Bucher, Thierry Carrel, Emmanuelle Catana, Yves Chalandon, Sabina De Geest, Olivier De Rougemont, Michael Dickenmann, Joëlle Lynn Dreifuss, Michel Duchosal, Thomas Fehr, Nicola Franscini, Christian Garzoni, Paola Gasche Soccal, Christophe Gaudet, Nicolas Goossens, Karine Hadaya, Jörg Halter, Dominik Heim, Christoph Hess, Sven Hillinger, Hans Hirsch, Patricia Hirt, Günther Hofbauer, Uyen Huynh-Do, Franz Immer, Michael Koller, Mirjam Laager, Bettina Laesser, Roger Lehmann, Alexander Leichtle, Christian Lovis, Oriol Manuel, Hans-Peter Marti, Pierre Yves Martin, Michele Martinelli, Valérie McLin, Katell Mellac, Aurelia Mercay, Karin Mettler, Nicolas Mueller, Antonia Müller, Thomas Müller, Ulrike Müller-Arndt, Beat Müllhaupt, Mirjam Nägeli, Graziano Oldani, Manuel Pascual, Klara Posfay-Barbe, Juliane Rick, Anne Rosselet, Simona Rossi, Silvia Rothlin, Frank Ruschitzka, Urs Schanz, Aurelia Schnyder, Macé Schuurmans, Thierry Sengstag, Federico Simonetta, Katharina Staufer, Susanne Stampf, Jürg Steiger, Guido Stirniman, Ueli Stürzinger, Christian Van Delden, Jean-Pierre Venetz, Julien Vionnet, Madeleine Wick, Markus Wilhlem, Patrick Yerly

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: kidney transplantation, donor specific antibodies, ABMR, graft loss, virtual cross-match, living donation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1104371/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/4477ab4529c049ca9d56bbf4349cc853

Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region

Authors: Marc Emmenegger, Elena De Cecco, David Lamparter, Raphaël P.B. Jacquat, Julien Riou, Dominik Menges, Tala Ballouz, Daniel Ebner, Matthias M. Schneider, Itzel Condado Morales, Berre Doğançay, Jingjing Guo, Anne Wiedmer, Julie Domange, Marigona Imeri, Rita Moos, Chryssa Zografou, Leyla Batkitar, Lidia Madrigal, Dezirae Schneider, Chiara Trevisan, Andres Gonzalez-Guerra, Alessandra Carrella, Irina L. Dubach, Catherine K. Xu, Georg Meisl, Vasilis Kosmoliaptsis, Tomas Malinauskas, Nicola Burgess-Brown, Ray Owens, Stephanie Hatch, Juthathip Mongkolsapaya, Gavin R. Screaton, Katharina Schubert, John D. Huck, Feimei Liu, Florence Pojer, Kelvin Lau, David Hacker, Elsbeth Probst-Müller, Carlo Cervia, Jakob Nilsson, Onur Boyman, Lanja Saleh, Katharina Spanaus, Arnold von Eckardstein, Dominik J. Schaer, Nenad Ban, Ching-Ju Tsai, Jacopo Marino, Gebhard F.X. Schertler, Nadine Ebert, Volker Thiel, Jochen Gottschalk, Beat M. Frey, Regina R. Reimann, Simone Hornemann, Aaron M. Ring, Tuomas P.J. Knowles, Milo A. Puhan, Christian L. Althaus, Ioannis Xenarios, David I. Stuart, Adriano Aguzzi

Source: iScience, Vol 26, Iss 2, Pp 105928- (2023)

Subject Terms: Immunology, Microbiology, Virology, Biological database, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004223000056; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/bea10cd3141c4742a1c82d8153f04eb2