Comparison of a novel potentiator of CFTR channel activity to ivacaftor in ameliorating mucostasis caused by cigarette smoke in primary human bronchial airway epithelial cells

Authors: Adrian Constantin Tanjala, Jia Xin Jiang, Paul D. W. Eckford, Mohabir Ramjeesingh, Canhui Li, Ling Jun Huan, Gabrielle Langeveld, Claire Townsend, Daniel V. Paone, Jakob Busch-Petersen, Roman Pekhletski, LiPing Tang, Vamsee Raju, Steven M. Rowe, Christine E. Bear

Source: Respiratory Research, Vol 25, Iss 1, Pp 1-10 (2024)

Subject Terms: Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1465-993X

Access URL: https://doaj.org/article/2da00d71ae6d4c6493740fb315b80270

Design, Synthesis, and Structure−Activity Relationship of Tropane Muscarinic Acetylcholine Receptor Antagonists.

Authors: Dramane I. Lainé, Zehong Wan, Hongxing Yan, Chongjie Zhu, Haibo Xie, Wei Fu, Jakob Busch-Petersen, Christopher Neipp, Roderick Davis, Katherine L. Widdowson, Frank E. Blaney, James Foley, Alicia M. Bacon, Edward F. Webb, Mark A. Luttmann, Miriam Burman, Henry M. Sarau, Michael Salmon, Michael R. Palovich, Kristen Belmonte

Source: Journal of Medicinal Chemistry; Aug2009, Vol. 52 Issue 16, p5241-5252, 12p

Discovery of Novel and Long Acting Muscarinic Acetylcholine Receptor Antagonists.

Authors: Jian Jin, Jakob Busch-Petersen, Yonghui Wang, Dongchuan Shi, Feng Wang, Roderick S. Davis, Qi Jin, Wei Fu, James J. Foley, Edward F. Webb, Chris J. Dehaas, Manuela Berlanga, Miriam Burman, Henry M. Sarau, Dwight M. Morrow, Parvathi Rao, Lorena A. Kallal, Michael L. Moore, Ralph A. Rivero, Michael Palovich

Source: Journal of Medicinal Chemistry. Jul2008, Vol. 51 Issue 16, p4866-4869. 4p.

Subject Terms: *SALTS, *ACETYLCHOLINE, *CHOLINE, *NEUROTRANSMITTERS, *DRUG development