Designing the next generation of clinical trials in intermediate AMD-a consensus driven, pragmatic, proof of concept early intervention study

Authors: Guymer, Robyn H. ^{a, b, 1, ⁎}, Rosenfeld, Philip J. ^c, Ehlers, Justis P. ^d, Attar, Mayssa ^e, Chen, Hao ^f, Ferris, Frederick ^g, Fujimoto, James G. ^h, Ip, Michael ⁱ, Pfau, Maximilian ^{j, k}, Saßmannshausen, Marlene ^l, Shen, Jie ^m, Zacks, David N. ⁿ, van Zyl, Tavé ^o, Wu, Zhichao ^{a, b}, Jaffe, Glenn J. ^{p, 1}

Source: In Experimental Eye Research June 2025 255

Returning Individual-Level Urgent or Emergent Research Results to Participants: The Project Baseline Health Study Experience

Authors: Pagidipati, Neha ^a, Heidenfelder, Brooke ^b, Kwee, Lydia Coulter ^c, Rodriguez, Fatima ^d, Chatterjee, Ranee ^e, Parikh, Kishan S. ^{a, f}, Khouri, Michel G. ^a, Stiller, Jennifer ^g, Eckstrand, Julie ^b, Marcom, P. Kelly ^h, Mettu, Priyatham S. ⁱ, Jaffe, Glenn J. ⁱ, Shashidhar, Sumana ^j, Swope, Susan ^j, Spielman, Susan ^j, Fraulo, Elizabeth ^k, Newby, L. Kristin ^{a, k}, Douglas, Pamela ^{a, k}, Wong, Charlene ^l, Green, Robert ^m, Shore, Scarlet ⁿ, Mega, Jessica ⁿ, Hernandez, Adrian ^{a, k}, Campbell, Paul ^o, Mahaffey, Kenneth W. ^{j, p}, Shah, Svati H. ^{a, b, c, g, k, ⁎}

Source: In American Journal of Medicine Open June 2025 13

MERLIN: Two-Year Results of Brolucizumab in Participants with Neovascular Age-Related Macular Degeneration and Persistent Retinal Fluid

Authors: Brown, David M. ^{1, 2}, Jaffe, Glenn J. ³, Wykoff, Charles C. ^{1, 2}, Adiguzel, Eser ⁴, Heier, Jeffrey S. ⁵, Khanani, Arshad M. ^{6, 7, ∗}

Source: In Ophthalmology February 2025 132(2):131-140

Onset of End-Stage Atrophic Age-Related Macular Degeneration as an End Point—A Delphi Study: Classification of Atrophy Meetings Report 7

Authors: Wu, Zhichao ^{1, 2, ∗}, Sadda, Srinivas R. ^{3, 4}, Ach, Thomas ⁵, Blodi, Barbara A. ⁶, Bottoni, Ferdinando ⁷, Chakravarthy, Usha ⁸, Chew, Emily Y. ⁹, Curcio, Christine A. ¹⁰, Ferris, Frederick L., III ¹¹, Fleckenstein, Monika ¹², Freund, K. Bailey ¹³, Grunwald, Juan E. ¹⁴, Holz, Frank G. ⁵, Jaffe, Glenn J. ¹⁵, Liakopoulos, Sandra ^{16, 17}, Lim, Tock Han ¹⁸, Monés, Jordi M. ^{12, 19}, Pagliarini, Sergio ²⁰, Pauleikhoff, Daniel ²¹, Pfau, Maximilian ^{5, 22, 23}, Rosenfeld, Philip J. ²⁴, Sarraf, David ²⁵, Schmitz-Valckenberg, Steffen ¹², Spaide, Richard F. ¹³, Sparrow, Janet R. ²⁶, Staurenghi, Giovanni ⁷, Tufail, Adnan ²⁷, Viola, Francesco ^{28, 29}, Guymer, Robyn H. ^{1, 2}

Source: In Ophthalmology Science March 2025

Macular Atrophy-Related Observations in Eyes Treated with the Port Delivery System with Ranibizumab in the Archway Trial

Authors: Jaffe, Glenn J. ^{1, ∗}, Cameron, Briana ², Barteselli, Giulio ², Callaway, Natalia ^{3, 4}, Skalak, Cindy ¹, Choong, John ¹, Gune, Shamika ²

Source: In Ophthalmology Retina February 2025

The novel secretome ST266 activates Akt and protects against oxidative stress-mediated injury in human RPE and Müller cells

Authors: Tang, Alan C., Besley, Nicholas A., Trimpey-Warfhatig, Rose, Yang, Ping, Wessel, Howard, Brown, Larry, Kirshner, Ziv, Jaffe, Glenn J.

Source: In Experimental Eye Research November 2024 248

Correlation Between Blue Fundus Autofluorescence and SD-OCT Measurements of Geographic Atrophy in Dry Age-Related Macular Degeneration

Authors: Ehlers, Justis P., McConville, Conor, Yordi, Sari, Cetin, Hasan, Cakir, Yavuz, Kalra, Gagan, Amine, Reem, Whitney, Jon, Whitmore, Victoria, Bonnay, Michelle, Reese, Jamie, Clark, Julie ^*, Zhu, Liansheng, Luo, Don, Jaffe, Glenn J., Srivastava, Sunil K.

Source: In American Journal of Ophthalmology October 2024 266:92-101

Faricimab Treat-and-Extend for Diabetic Macular Edema: Two-Year Results from the Randomized Phase 3 YOSEMITE and RHINE Trials

Authors: Aaberg, Thomas, Jr., Abbey, Ashkan, Abdulaeva, Elmira, Abengoechea, Santiago, Abraham, Prema, Ach, Thomas, Adams, Serrhel, Adan Civera, Alfredo, Adrean, Sean, Agostini, Hansjurgen, Alam, Suhail, Alezzandrini, Arturo, Alfaro, Virgil, Aliseda, Daniel, Almony, Arghavan, Amat, Pedro, Amini, Payam, Antoszyk, Andrew, Arias, Luis, Asaria, Riaz, Avila, Marcos, Awh, Carl C., Bafalluy, Joaquin, Baker, Carl, Bandello, Francesco, Barakat, Mark, Barraza, Karen, Bator, Gyorgy, Baumal, Caroline, Belfort, Rubens, Jr., Bergstrom, Chris, Bertolucci, George, Bochow, Thomas, Bolz, Matthias, Borcz, Emilia, Bordon, Arnaldo, Boyer, David, Bratko, Galina, Brent, Michael, Brown, Jamin, Brown, David M., Budzinskaya, Maria, Buffet, Sylvia, Burgess, Stuart, Burton, Ben, Busquets, Miguel, Cabrera, Francisco, Cagini, Carlo, Calzada, Jorge, Campochiaro, Peter, Carlson, John, Castellarin, Alessandro, Cava, Carlos, Chaikitmongkol, Voraporn, Chan, Clement, Chang, Emmanuel, Chang, Jonathan, Chang, Andrew, Charles, Steve, Chaudhry, Nauman, Chee, Caroline, Chen, Judy, Chen, Fred, Chen, Shih-Jen, Cheong-Leen, Richard, Chiang, Allen, Chittum, Mark, Chow, David, Connolly, Brian, Cornut, Pierre Loic, Csaky, Karl, Danzig, Carl, Das, Arup, Daskalov, Vesselin, Desco, Carmen, Dessouki, Amr, Dickinson, John, Do, Brian, Dollin, Michael, Dugel, Pravin, Dusova, Jaroslava, Eichenbaum, David, Eldem, Bora, Engstrom, Robert, Ernest, Jan, Escobar, Joan Josep, Esposti, Simona, Eter, Nicole, Falk, Naomi, Farkas, Andrej, Feiner, Leonard, Feltgen, Nicolas, Fernandez, Carlos, Fernandez Vega, Alvaro, Ferrone, Philip, Figueira, Joao, Figueroa, Marta, Findl, Oliver, Fine, Howard, Fortun, Jorge, Fox, Gregory M., Foxman, Scott, Framme, Carsten, Fraser-Bell, Samantha, Fu, Arthur, Fukutomi, Akira, Fung, Nicholas, Furno Sola, Federico, Gallego-Pinazo, Roberto, Garcia, Renata, Garcia-Layana, Alfredo, Gawecki, Maciej, George, Sheen, Ghanchi, Faruque, Ghorayeb, Ghassan, Goldberg, Roger, Goldstein, Michaella, Gomes, Nuno, Ulla, Francisco Gomez, Gonzalez, Victor, Greven, Craig, Gupta, Sunil, Guzman, Miguel, Harris, Martin, Hatz, Katja, Hau, Vivienne, Hau, Vincent, Hayashi, Ken, Heier, Jeffrey, Herba, Ewa, Hershberger, Vrinda, Higgins, Patrick, Hirakata, Akito, Ho, Allen, Holekamp, Nancy, Honda, Shigeru, Hsu, Jason, Hu, Allen, Hurcikova, Maria, Ikeda, Yasuhiro, Isernhagen, Ricky, Ito, Yasuki, Jackson, Tim, Jacoby, Rachael, Jafree, Afsar, Javey, Golnaz, Javid, Cameron, Jhaveri, Chirag, Johnson, Mark, Kacerík, Marek, Kaluzny, Jakub, Kampik, Daniel, Kang, Se Woong, Kapoor, Kapil, Karabas, Levent, Kawasaki, Tsutomu, Kerenyi, Agnes, Khanani, Arshad, Khurana, Rahul, Kim, Brian, Kimura, Kazuhiro, Kishino, Genichiro, Kitano, Shigehiko, Klein-Mascia, Kendra, Kokame, Gregg, Korobelnik, Jean Francois, Kulikov, Alexey, Kuriyan, Ajay, Kwong, Henry, Kwun, Robert, Lai, Timothy, Lai, Chi-Chun, Laird, Philip, Lalonde, Laurent, Lanzetta, Paolo, Larsen, Michael, Laugesen, Caroline, Lavinsky, Daniel, Lebreton, Olivier, Lee, Seong, Levy, Jaime, Lipkova, Blandina, Liu, Mimi, Liu, Judy, Lohmann, Chris P., London, Nikolas, Lorenz, Katrin, Lotery, Andrew, Lozano Rechy, David, Lujan, Silvio, Ma, Patrick, Maeno, Takatoshi, Mahmood, Sajjad, Makkouk, Fuad, Malik, Khurram, Marcus, Dennis, Margherio, Alan, Mastropasqua, Leonardo, Maturi, Raj, McCabe, Frank, McKibbin, Martin, Mehta, Hemal, Menon, Geeta, Mentes, Jale, Michalska-Malecka, Katarzyna, Misheva, Aneta, Mitamura, Yoshinori, Mitchell, Paul, Modi, Yasha, Mohamed, Quresh, Montero, Javier, Moore, Jeffrey, Morales Canton, Virgilio, Morori-Katz, Haia, Morugova, Tatiana, Murakami, Tomoaki, Muzyka-Wozniak, Maria, Nardi, Marco, Nemcansky, Jan, Nester-Ostrowska, Kamila, Neto, Julio, Newell, Charles, Nicolo, Massimo, Nielsen, Jared, Noda, Kousuke, Obana, Akira, Ogata, Nahoko, Oh, Hideyasu, Oh, Kean, Ohr, Matthew, Oleksy, Piotr, Oliver, Scott, Olivier, Sebastien, Osher, James, Ozcalışkan, Sehnaz, Ozturk, Banu, Papp, Andras, Park, Kyu Hyung, Parke, D. Wilkin, Parravano, Maria Cristina, Patel, Sugat, Patel, Sunil, Pearce, Ian, Pearlman, Joel, Penha, Fernando, Perente, Irfan, Perkins, Stephen, Pertile, Grazia, Petkova, Iva, Peto, Tunde, Pieramici, Dante, Pollreisz, Andreas, Pongsachareonnont, Pear, Pozdeyeva, Nadezhda, Priglinger, Siegfried, Qureshi, Jawad, Raczynska, Dorota, Rajagopalan, Rajesh, Ramirez Estudillo, Juan, Raskauskas, Paul, Rathod, Rajiv, Razavi, Hessam, Regillo, Carl, Ricci, Federico, Rofagha, Soraya, Romanczak, Dominika, Romanowska-Dixon, Bożena, Rosberger, Daniel, Rosenblatt, Irit, Rosenblatt, Brett, Ross, Adam, Ruamviboonsuk, Paisan, Ruiz Moreno, Jose Maria, Salomão, Gustavo, Sandhu, Sukhpal, Sandner, Dirk, Sararols, Laura, Sawada, Osamu, Schadlu, Ramin, Schlottmann, Patricio, Schuart, Claudia, Seitz, Berthold, Seres, András, Sermet, Figen, Shah, Sandeep, Shah, Ankur, Shah, Rohan, Sharma, Sumit, Sheidow, Thomas, Sheth, Veeral, Shimouchi, Akito, Shimura, Masahiko, Sikorski, Bartosz, Silva, Rufino, Singer, Michael, Singerman, Lawrence, Singh, Rishi, Souied, Eric, Spinak, David J., Spital, Georg, Steinle, Nathan, Stern, Jeffrey, Stoller, Glenn, Stoltz, Robert, Stone, Cameron, Stone, Amy, Suan, Eric, Sugimoto, Masahiko, Sugita, Iichiro, Sun, Jennifer, Sun, Xiaodong, Suner, Ivan, Szalczer, Lajos, Szecsko, Timea, Tabassian, Ali, Tadayoni, Ramin, Takagi, Hitoshi, Takayama, Kei, Taleb, Alexandre, Talks, James, Tan, Gavin, Tanabe, Teruyo, Taylor, Stanford, Thach, Allen, Thompson, John, Tlucek, Paul, Torti, Robert, Tosheva Guneva, Daniela, Toth-Molnar, Edit, Uchiyama, Eduardo, Vajas, Attila, Varma, Deepali, Varsanyi, Balazs, Vassileva, Petja, Vaz-Pereira, Sara, Veith, Miroslav, Vela, Jose Ignacio, Viola, Francesco, Virgili, Gianni, Vogt, Gábor, Vorum, Henrik, Weber, Pamela, Wecke, Thoalf, Wee, Raymond, Weger, Martin, Weishaar, Paul, Wells, John A., Wickremasinghe, Sanjeewa, Williams, Thomas Reginald, Williams, Thomas, Williams, Geoff, Wolf, Armin, Wolfe, Jeremy, Wong, James, Wong, David, Wong, Ian, Wong, Robert, Wowra, Bogumil, Wykoff, Charles C., Wylęgała, Edward, Yang, Chang-Hao, Yasukawa, Tsutomu, Yates, Paul, Yilmaz, Gursel, Yiu, Glenn, Yoon, Young Hee, Yoreh, Barak, Yoshida, Shigeo, Yu, Hyeong Gon, Yu, Seung Young, Yurieva, Tatiana, Zacharias, Leandro, Zaczek Zakrzewska, Karolina, Zambrano, Alberto, Zatorska, Barbara, Zeolite, Carlos, Zheutlin, Jeffrey, Wong, Tien Y., Haskova, Zdenka, Asik, Kemal, Baumal, Caroline R., Csaky, Karl G., Ives, Jane A., Jaffe, Glenn J., Korobelnik, Jean-François, Lin, Hugh, Murata, Toshinori, Schlottmann, Patricio G., Seres, András I., Silverman, David, Tang, Yannan

Source: In Ophthalmology June 2024 131(6):708-723

Gene therapy for neovascular age-related macular degeneration by subretinal delivery of RGX-314: a phase 1/2a dose-escalation study

Authors: Campochiaro, Peter A ^*, Avery, Robert, Brown, David M, Heier, Jeffrey S, Ho, Allen C, Huddleston, Stephen M, Jaffe, Glenn J, Khanani, Arshad M, Pakola, Stephen, Pieramici, Dante J, Wykoff, Charles C, Van Everen, Sherri

Source: In The Lancet 20-26 April 2024 403(10436):1563-1573

Gradeability and Reproducibility of Geographic Atrophy Measurement in GATHER-1, a Phase II/III Randomized Interventional Trial

Authors: Li, Angela S., Myers, Justin, Stinnett, Sandra S., Grewal, Dilraj S., Jaffe, Glenn J.

Source: In Ophthalmology Science March-April 2024 4(2)

Imaging Features of Retinal Vasculitis and/or Retinal Vascular Occlusion after Brolucizumab Treatment in the Postmarketing Setting

Authors: Grewal, Dilraj S., Wykoff, Charles C., D’Souza, Divya, Jehl, Valentine, Alecu, Iulian, Jaffe, Glenn J.

Source: In Ophthalmology Science January-February 2024 4(1)

Reticular Pseudodrusen: Interreader Agreement of Evaluation on OCT Imaging in Age-Related Macular Degeneration

Authors: Wu, Zhichao, Schmitz-Valckenberg, Steffen, Blodi, Barbara A., Holz, Frank G., Jaffe, Glenn J., Liakopoulos, Sandra, Sadda, Srinivas R., Bonse, Mari, Brown, Tyler, Choong, John, Clifton, Bailey, Corradetti, Giulia, Corvi, Federico, Dieu, Andrew C., Dooling, Vivienne, Pak, Jeong W., Saßmannshausen, Marlene, Skalak, Cindy, Thiele, Sarah, Guymer, Robyn H.

Source: In Ophthalmology Science December 2023 3(4)

Efficacy and safety of avacincaptad pegol in patients with geographic atrophy (GATHER2): 12-month results from a randomised, double-masked, phase 3 trial

Authors: Alezzandrini, Arturo, Francone, Anibal Andres, Bafalluy, Joaquín, Bainttein, Silvina, Luna Pinto, Jose, Saravia, Mario, Vidosevich, Matko, Zeolite, Carlos, Furno Sola, Federico, Chang, Andrew, Cornish, Elisa Eleanor Guida, Nguyen, Thanh, Findl, Oliver, Haas, Anton, Kralinger, Martina, Sacu, Stefan, Postelmans, Laurence Dominique, Farah, Michel, Maia, Mauricio, Nehemy, Marcio, Ali, Fareed, Brent, Michael, Dollin, Michael, Gonder, John, Kherani, Amin, Merkur, Andrew, Tuli, Raman, Lopera, Monica Marie, Rodriguez, Francisco, Bradvica, Mario, Ernest, Jan, Kalijurand, Kuldar, Noor, Kai, Cohen, Yves, Creuzot-Garcher, Catherine, De Bats, Flore, Devin, François, Français-Maury, Catherine, Kodjikian, Laurent, Korobelnik, Jean François, Le Mer, Yannick, Quaranta El Maftouhi, Maddalena, Razavi, Sam, Souied, Eric, Tadayoni, Ramin, Weber, Michel, Eter, Nicole, Feltgen, Nicolas, Grisanti, Salvatore, Walter, Peter, Liegl, Raffael, Lorenz, Katrin, Spital, Georg, Priglinger, Siegfried, Spitzer, Martin, Volker, Michael, Krohne, Tim, Jochmann, Claudia, Lohmann, Chris Patrick, Framme, Carsten, Kerenyi, Agnes, Papp, Andras, Seres, Andras, Toth-Molnar, Edit, Tsorbatzoglou, Alexis, Vajas, Atilla, Varsanyi, Balázs, Vogt, Gabor, Bar, Asaf, Eting, Eva, Hauser, David, Levy, Jamie, Mathalone, Nurit, Morori-Katz, Haia, Rosenblatt, Irit, Soudry-Zayit, Shiri, Trivizky, Omert, Bandello, Francesco, Ciardella, Antonio Pasquale, Figus, Michele, Giansanti, Fabrizio, Lanzetta, Paolo, Mariotti, Cesare, Mastropasqua, Leonardo, Midena, Edoardo, Parmeggiani, Francesco, Ricci, Federico, Simonelli, Francesca, Staurenghi, Giovanni, Viola, Francesco, Varano, Monica, Laganovska, Guna, Cisiecki, Sławomir, Jedrzejewski, Wojciech, Kaluzny, Jakub, Misiuk-Hojło, Marta, Abengoechea, Santiago, Iribarren, Javier Araiz, Ascaso, Franciso Javier, Cubero, Juan Manuel, Gallego-Pinazo, Roberto, Gomez-Ulla De Irazazabal, Francisco, Mestre, Ignasi Jürgens, Mones I Carilla, Jordi Manel, Montero Moreno, Javier, María Ruiz Moreno, José, Sararols Ramsay, Laura, Garcia Layana, Alfredo, Downey, Louise, Abraham, Prema, Alfaro, Daniel Virgil, Bagheri, Nika, Barbazetto, Irene, Benevento, Joseph, Bernstein, Paul, Bertolucci, George, Bhavsar, Abdhish, Bridges, William, Brooks, Jr, Harold Logan, Brown, Jamin, Brucker, Alexander, Calvo, Charles M., Capone, Antonio, Carlson, John, Chan, Clement, Chang, Emmanuel, Chan-Kai, Brian, Chaudhry, Nauman, Chen, Sanford, Csaky, Karl, Cummings, Howard, Danzig, Carl, Dessouki, Amr, Dyer, David, Eaton, Alexander, Eichenbaum, David, Faber, David, Feldman, Robert, Finnen, Neil, Freeman, William, Frenkel, Ronald, Gonzales, Christine, Gonzalez, Victor, Gross, John, Gupta, Sunil, Hall, Edward, Han, Min-Kyu, Heier, Jeffrey, Hershberger, Vrinda, Higgins, Patrick, Hsu, Jason, Ip, Michael, Jablon, Eric, Jewart, Brian, John, Vishak, Jonisch, Jonathan, Joondeph, Brian, Kay, Christine, Khanani, Arshad, Kokame, Gregg T., Kwun, Robert, Lai, Michael, Lally, David, Laud, Ketan, Lavina, Adrian, Lee, Michael, Lin, Phoebe, Lin, Haijiang, Manoharan, Niranjan, Marcus, Dennis, Martidis, Adam, McCabe, Frank, Nielsen, Jared, Osher, James, Palmer, James, Patel, Sunil, Pearlman, Joel, Perkins, Stephen, Pirouz, Ashkan, Qureshi, Jawad, Randolph, John, Piri, Niloofar, Rosenfeld, Phillip, Saperstein, David, Scartozzi, Richard, Schwartz, Steven, Sharma, Ashish, Sharma, Atul, Sheth, Veeral, Singer, Michael, Spinak, David, Suan, Eric, Tabandeh, Homayoun, Tabassian, Ali, Uchiyama, Eduardo, Varenhorst, Michael, Wagner, Alan, Warrow, David, Wells, III, John, Wong, Robert, Wong, Keye, Wykoff, Charles, Xavier, Samantha, Ysasaga, Edward, Khanani, Arshad M ^*, Patel, Sunil S, Danzig, Carl J, Eichenbaum, David A, Wykoff, Charles C, Heier, Jeffrey S, Lally, David R, Monés, Jordi, Nielsen, Jared S, Sheth, Veeral S, Kaiser, Peter K, Clark, Julie, Zhu, Liansheng, Patel, Hersh, Tang, Justin, Desai, Dhaval, Jaffe, Glenn J

Source: In The Lancet 21-27 October 2023 402(10411):1449-1458

Joint Multimodal Deep Learning-based Automatic Segmentation of Indocyanine Green Angiography and OCT Images for Assessment of Polypoidal Choroidal Vasculopathy Biomarkers

Authors: Loo, Jessica, Teo, Kelvin Y.C., Vyas, Chinmayi H., Jordan-Yu, Janice Marie N., Juhari, Amalia B., Jaffe, Glenn J., Cheung, Chui Ming Gemmy, Farsiu, Sina

Source: In Ophthalmology Science September 2023 3(3)

Macular Telangiectasia Type 2: A Classification System Using MultiModal Imaging MacTel Project Report Number 10

Authors: Chew, Emily Y., Peto, Tunde, Clemons, Traci E., Sallo, Ferenc B., Pauleikhoff, Daniel, Leung, Irene, Jaffe, Glenn J., Heeren, Tjebo F.C., Egan, Catherine A., Charbel Issa, Peter, Balaskas, Konstantinos, Holz, Frank G., Gaudric, Alain, Bird, Alan C., Friedlander, Martin

Source: In Ophthalmology Science June 2023 3(2)

Baseline Microperimetry and OCT in the RUSH2A Study: Structure−Function Association and Correlation With Disease Severity

Authors: Lad, Eleonora M., Duncan, Jacque L., Liang, Wendi, Maguire, Maureen G., Ayala, Allison R., Audo, Isabelle, Birch, David G., Carroll, Joseph, Cheetham, Janet K., Durham, Todd A., Fahim, Abigail T., Loo, Jessica, Deng, Zengtian, Mukherjee, Dibyendu, Heon, Elise, Hufnagel, Robert B., Guan, Bin, Iannaccone, Alessandro, Jaffe, Glenn J., Kay, Christine N., Michaelides, Michel, Pennesi, Mark E., Vincent, Ajoy, Weng, Christina Y., Farsiu, Sina

Source: In American Journal of Ophthalmology December 2022 244:98-116

MERLIN: Phase 3a, Multicenter, Randomized, Double-Masked Trial of Brolucizumab in Participants with Neovascular Age-Related Macular Degeneration and Persistent Retinal Fluid

Authors: Khanani, Arshad M., Brown, David M., Jaffe, Glenn J., Wykoff, Charles C., Adiguzel, Eser, Wong, Randall, Meng, Xiangyi, Heier, Jeffrey S.

Source: In Ophthalmology September 2022 129(9):974-985

OCT Signs of Early Atrophy in Age-Related Macular Degeneration: Interreader Agreement: Classification of Atrophy Meetings Report 6

Authors: Wu, Zhichao, Pfau, Maximilian, Blodi, Barbara A., Holz, Frank G., Jaffe, Glenn J., Liakopoulos, Sandra, Sadda, Srinivas R., Staurenghi, Giovanni, Bjelopera, Elvira, Brown, Tyler, Chang, Petrus, Choong, John, Corradetti, Giulia, Corvi, Federico, Domalpally, Amitha, Hurtenbach, Cynthia, Nittala, Muneeswar Gupta, Olson, Anthony, Pak, Jeong W., Pappe, Judith, Saßmannshausen, Marlene, Skalak, Cindy, Thiele, Sarah, Guymer, Robyn H., Schmitz-Valckenberg, Steffen

Source: In Ophthalmology Retina January 2022 6(1):4-14

Pneumatic Vitreolysis with Perfluoropropane for Vitreomacular Traction with and without Macular Hole: DRCR Retina Network Protocols AG and AH

Authors: Chan, Clement K., Mein, Calvin E., Glassman, Adam R., Beaulieu, Wesley T., Calhoun, Claire T., Jaffe, Glenn J., Jampol, Lee M., MacCumber, Mathew W., Maguire, Maureen G., Maturi, Raj K., Salehi-Had, Hani, Rofagha, Soraya, Sun, Jennifer K., Martin, Daniel F.

Source: In Ophthalmology November 2021 128(11):1592-1603

Predominantly Persistent Subretinal Fluid in the Comparison of Age-Related Macular Degeneration Treatments Trials

Authors: Core, Jason Q., Pistilli, Maxwell, Daniel, Ebenezer, Grunwald, Juan E., Toth, Cynthia A., Jaffe, Glenn J., Hua, Peiying, Martin, Daniel F., Ying, Gui-Shuang, Maguire, Maureen G.

Source: In Ophthalmology Retina October 2021 5(10):962-974