Transgenic viral expression of PH-20, IL-12, and sPD1-Fc enhances immune cell infiltration and anti-tumor efficacy of an oncolytic virus

Authors: Soon-Oh Hong, Joonsung Kim, Sungmin Lee, Jaeil Shin, Hwanjun Choi, Eunjin Lee, Hyesoo Kang, Hyesun Lee, Soondong Lee, Naeun Yun, Jiwon An, Heonsik Choi, Hyeree Kim, Wonseok Kang, Yeup Yoon, Sujeong Kim

Source: Molecular Therapy: Oncolytics, Vol 30, Iss , Pp 301-315 (2023)

Subject Terms: MT: Regular Issue, oncolytic virus, vaccinia virus, KLS-3020, PH-20, interleukin-12, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2372770523000670; https://doaj.org/toc/2372-7705

Access URL: https://doaj.org/article/620b9a85f81c43d88ef59f991c8e8252

Munc18-1 induces conformational changes of syntaxin-1 in multiple intermediates for SNARE assembly

Authors: Sanghwa Lee, Jonghyeok Shin, Younghun Jung, Heyjin Son, Jaeil Shin, Cherlhyun Jeong, Dae-Hyuk Kweon, Yeon-Kyun Shin

Source: Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/9b8cf37ff71545a589930604bb4e66e8

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A Chemical Controller of SNARE-Driven Membrane Fusion That Primes Vesicles for Ca²⁺-Triggered Millisecond Exocytosis.

Authors: Paul Heo¹, Yoosoo Yang^1,2, Kyu Young Han^3,4, Byoungjae Kong¹, Jong-Hyeok Shin¹, Younghoon Jung¹, Cherlhyun Jeong², Jaeil Shin⁵, Yeon-Kyun Shin⁵, Taekjip Ha^1,3,6,7,8, tjha@jhu.edu, Dae-Hyuk Kweon¹, dhkweon@skku.edu

Source: Journal of the American Chemical Society; 4/6/2016, Vol. 138 Issue 13, p4512-4521, 10p

A Chemical Controller of SNARE-Driven Membrane Fusion That Primes Vesicles for Ca2+-Triggered Millisecond Exocytosis.

Authors: Paul Heo¹, Yoosoo Yang^1,2, Kyu Young Han^3,4, Byoungjae Kong¹, Jong-Hyeok Shin¹, Younghoon Jung¹, Cherlhyun Jeong², Jaeil Shin⁵, Yeon-Kyun Shin⁵, Taekjip Ha^1,3,6,7,8, tjha@jhu.edu, Dae-Hyuk Kweon¹, dhkweon@skku.edu

Source: Journal of the American Chemical Society; 4/6/2016, Vol. 138 Issue 13, p4512-4521, 10p

Synaptotagmin-1 Is an Antagonist for Munc18-1 in SNARE Zippering.

Authors: Xiaochu Lou¹, Jaeil Shin¹, Yoosoo Yang², Jaewook Kim², Yeon-Kyun Shin¹ colishin@iastate.edu

Source: Journal of Biological Chemistry. 4/17/2015, Vol. 290 Issue 16, p10535-00543. 9p.

Subject Terms: *SYNAPTOTAGMINS, *CALCIUM-binding proteins, *EXOCYTOSIS, *MEMBRANE fusion, *SINGLE molecules spectra, *FLUORESCENCE

Multiple conformations of a single SNAREpin between two nanodisc membranes reveal diverse pre-fusion states.

Authors: Jaeil SHIN¹, Xiaochu LOU¹, Dae-Hyuk KWEON², Yeon-Kyun SHIN^1,3 colishin@iastate.edu

Source: Biochemical Journal. 4/1/2014, Vol. 459 Issue 1, following p95-102. 12p.

Subject Terms: *NEUROTRANSMITTERS, *SINGLE molecules, *FLUORESCENCE resonance energy transfer, *SYNAPTOTAGMINS, *PROTEIN receptors, *MEMBRANE proteins

Dissection of SNARE-driven membrane fusion and neuroexocytosis by wedging small hydrophobic molecules into the SNARE zipper.

Authors: Yoosoo Yang, Jae Yoon Shin, Jung-Mi Oh, Chang Hwa Jung, Yunha Hwang, Sehyun Kim, Jun-Seob Kim, Kee-Jung Yoon, Ji-Young Ryu, Jaeil Shin, Jae Sung Hwang, Tae-Young Yoon, Yeon-Kyun Shin, Dae-Hyuk Kweon

Source: Proceedings of the National Academy of Sciences of the United States of America; 12/21/2010, Vol. 107 Issue 51, p22145-22150, 6p, 1 Diagram, 3 Graphs

Subject Terms: DISSECTION, PROTEINS, NEUROTRANSMITTERS, CELL membranes, MEMBRANE fusion

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