Case report on severe myelin oligodendrocyte glycoprotein antibody-associated disease relapse after ectopic pregnancy and laparoscopic medical abortion: relevance of peripheral inflammation for demyelinating disease activity

Authors: Lidija Smertinaite, Katja Selin, Roosa Vaitiniemi, Ramojus Balevicius, Evangelia Kollia, Tobias Granberg, Maria Isabel Leite, Jacqueline Palace, Helene Blad, Virginija D. Karrenbauer

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: magnetic resonance imaging, cerebrospinal fluid, demyelinating disease, myelin oligodendrocyte glycoprotein antibody-associated disease, ectopic pregnancy, multiple sclerosis, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1582789/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/fe7a6ff34bc642539439596f2bdeff56

Characterizing mortality in patients with AQP4‐Ab+ neuromyelitis optica spectrum disorder

Authors: Anna Francis, Emily Gibbons, Jeffrey Yu, Karissa Johnston, Hannah Rochon, Lauren Powell, Maria Isabel Leite, Saif Huda, Adrian Kielhorn, Jacqueline Palace

Source: Annals of Clinical and Translational Neurology, Vol 11, Iss 7, Pp 1942-1947 (2024)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2328-9503

Access URL: https://doaj.org/article/09453afc4cb94e95998fb30454cf1204

Brain reserve and physical disability in secondary progressive multiple sclerosis

Authors: Nevin John, Jeremy Chataway, Jacqueline Palace, Gavin Giovannoni, David Paling, Frederik Barkhof, Floriana De Angelis, Lorraine Smith, Thomas Williams, Martin Duddy, James Overell, Basil Sharrack, Sebastien Ourselin, Allan Walker, Siddharthan Chandran, Richard Nicholas, Shuna Colville, Peter Connick, Carolyn Young, Jeremy Hobart, Anisha Doshi, Sharmilee Gnanapavan, Helen Ford, Baljean Dhillon, Thanh Phan, Arman Eshaghi, Julia Aram, Nigel Stallard, James Cameron, Brendan McLean, Matthew Craner, Domenico Plantone, Jonathan Stutters, Ferran Prados Carrasco, Marie Braisher, Moira Ross, Gina Cranswick, Sue H Pavitt, Clive Hawkins, Roger Bastow, Daisy Mollison, Waqar Rashid, Joe Guadagno, Nikolaos Evangelou, Seema Kalra, Alberto Calvi, Yingtong Li, Tiggy Beyene, Vanessa Bassan, Alvin Zapata, Dawn Lyle, Heinke Arndt

Source: BMJ Neurology Open, Vol 6, Iss 2 (2024)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://neurologyopen.bmj.com/content/6/2/e000670.full; https://doaj.org/toc/2632-6140

Access URL: https://doaj.org/article/03779c5cc9264a67966bb74f4a5ef24d

Protocol of a prospective multicenter study on comorbidity impact on multiple sclerosis and antibody-mediated diseases of the central nervous system (COMMIT)

Authors: Sara Samadzadeh, Rafl Adnan, Paulina Berglova, Mahdi Barzegar, Birgit Debrabant, Stine Gundtoft Roikjaer, Michael Levy, Axel Petzold, Jacqueline Palace, Eoin P. Flanagan, Sara Mariotto, Soeren T. Skou, Anne Froelich, Itay Lotan, Silvia Messina, Ruth Geraldes, Susanna Asseyer, Hadas Stiebel-Kalish, Frederike Cosima Oertel, Vahid Shaygannejad, Mohammad Ali Sahraian, Ho Jin Kim, Jeffrey L. Bennett, Chotima Böttcher, Hanna G. Zimmermann, Brian G. Weinshenker, Friedemann Paul, Nasrin Asgari

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: multiple sclerosis, neuromyelitis optica spectrum disorder, myelin oligodendrocyte glycoprotein antibody-associated disease, antibody-mediated diseases of the central nervous system, comorbidity, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1380025/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/2b740f34241942d389bbfe03e7b0adef

Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases

Authors: Alistair T. Pagnamenta, Carme Camps, Edoardo Giacopuzzi, John M. Taylor, Mona Hashim, Eduardo Calpena, Pamela J. Kaisaki, Akiko Hashimoto, Jing Yu, Edward Sanders, Ron Schwessinger, Jim R. Hughes, Gerton Lunter, Helene Dreau, Matteo Ferla, Lukas Lange, Yesim Kesim, Vassilis Ragoussis, Dimitrios V. Vavoulis, Holger Allroggen, Olaf Ansorge, Christian Babbs, Siddharth Banka, Benito Baños-Piñero, David Beeson, Tal Ben-Ami, David L. Bennett, Celeste Bento, Edward Blair, Charlotte Brasch-Andersen, Katherine R. Bull, Holger Cario, Deirdre Cilliers, Valerio Conti, E. Graham Davies, Fatima Dhalla, Beatriz Diez Dacal, Yin Dong, James E. Dunford, Renzo Guerrini, Adrian L. Harris, Jane Hartley, Georg Hollander, Kassim Javaid, Maureen Kane, Deirdre Kelly, Dominic Kelly, Samantha J. L. Knight, Alexandra Y. Kreins, Erika M. Kvikstad, Craig B. Langman, Tracy Lester, Kate E. Lines, Simon R. Lord, Xin Lu, Sahar Mansour, Adnan Manzur, Reza Maroofian, Brian Marsden, Joanne Mason, Simon J. McGowan, Davide Mei, Hana Mlcochova, Yoshiko Murakami, Andrea H. Németh, Steven Okoli, Elizabeth Ormondroyd, Lilian Bomme Ousager, Jacqueline Palace, Smita Y. Patel, Melissa M. Pentony, Chris Pugh, Aboulfazl Rad, Archana Ramesh, Simone G. Riva, Irene Roberts, Noémi Roy, Outi Salminen, Kyleen D. Schilling, Caroline Scott, Arjune Sen, Conrad Smith, Mark Stevenson, Rajesh V. Thakker, Stephen R. F. Twigg, Holm H. Uhlig, Richard van Wijk, Barbara Vona, Steven Wall, Jing Wang, Hugh Watkins, Jaroslav Zak, Anna H. Schuh, Usha Kini, Andrew O. M. Wilkie, Niko Popitsch, Jenny C. Taylor

Source: Genome Medicine, Vol 15, Iss 1, Pp 1-25 (2023)

Subject Terms: Genome sequencing, Rare diseases, Structural variant, Splice site variant, Non-coding, Diagnostic yield, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/c9f00f4d0c70402d8c69f3f7e4981fbc

Assessing the Utility of ColabFold and AlphaMissense in Determining Missense Variant Pathogenicity for Congenital Myasthenic Syndromes

Authors: Finlay Ryan-Phillips, Leighann Henehan, Sithara Ramdas, Jacqueline Palace, David Beeson, Yin Yao Dong

Source: Biomedicines, Vol 12, Iss 11, p 2549 (2024)

Subject Terms: CMS, AlphaFold2, ColabFold, AlphaMissense, pathogenicity, prediction, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/12/11/2549; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/165e2ec6b1cd4076996f63eba6eaf57e

Patient Pathway to Diagnosis of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD): Findings from a Multinational Survey of 204 Patients

Authors: Jonathan D. Santoro, Jennifer Gould, Zoya Panahloo, Ella Thompson, Julia Lefelar, Jacqueline Palace

Source: Neurology and Therapy, Vol 12, Iss 4, Pp 1081-1101 (2023)

Subject Terms: Demyelination, Diagnosis, Myelin oligodendrocyte glycoprotein (MOG), Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), Neurology, Patient perspective, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2193-8253; https://doaj.org/toc/2193-6536

Access URL: https://doaj.org/article/188df727b97447d49337ecec0c582124

A multicentre, prospective, double-blind study comparing the accuracy of autoantibody diagnostic assays in myasthenia gravis: the SCREAM studyResearch in context

Authors: Zhiguo Li, Chao Zhang, Ting Chang, Xinghu Zhang, Huan Yang, Feng Gao, Jinzhou Feng, Hongbo Liu, Sheng Chen, Lihua Wang, Chunsheng Yang, Huining Li, Yuesong Pan, Jacqueline Palace, Fu-Dong Shi, Minshu Li, Pei Zheng, Nan Yao, Siting Wu, Xuelu Ding, Guoqiang Chang, Li Yang, Moli Fan, Xin Liu, Qiuyu Wang, Chang, Ruan, Zhang, Wang, Tian, Pan, Yang, Jie Lv, Xiaodan Kong, Yu Wang

Source: The Lancet Regional Health. Western Pacific, Vol 38, Iss , Pp 100846- (2023)

Subject Terms: Myasthenia gravis, Autoantibody diagnostic assays, Anti-acetylcholine receptor antibody, Anti-muscle-specific kinase antibody, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666606523001645; https://doaj.org/toc/2666-6065

Access URL: https://doaj.org/article/5da668214ce7427f87472322c33f1285

Metabolomics detects clinically silent neuroinflammatory lesions earlier than neurofilament-light chain in a focal multiple sclerosis animal model

Authors: Tianrong Yeo, Halwan Bayuangga, Marcus Augusto-Oliveira, Megan Sealey, Timothy D. W. Claridge, Rachel Tanner, David Leppert, Jacqueline Palace, Jens Kuhle, Fay Probert, Daniel C. Anthony

Source: Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-15 (2022)

Subject Terms: Multiple sclerosis, Metabolomics, Neurofilament-light, Delayed-type hypersensitivity, Biomarker, Blood, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/ed702fcc50c7445ca41523389ff78f61

Patient-reported impact of myasthenia gravis in the real world: findings from a digital observational survey-based study (MyRealWorld MG)

Authors: Jacqueline Palace, Kristl G Claeys, Andreas Meisel, Casey Quinn, Srikanth Muppidi, Francesco Saccà, Sonia Berrih-Aknin, Mark Larkin, Jon Beauchamp, Sandra Paci, Glenn Philips, Fatemeh Amini, Femke De Ruyck, Joyce Ramirez

Source: BMJ Open, Vol 13, Iss 5 (2023)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/13/5/e068104.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/1abfca6660ea4b04b7ca9028a4ffc0d7

A single relapse induces worsening of disability and health-related quality of life in patients with neuromyelitis optica spectrum disorder

Authors: Achim Berthele, Michael Levy, Dean M. Wingerchuk, Sean J. Pittock, Shulian Shang, Adrian Kielhorn, Minying Royston, Guido Sabatella, Jacqueline Palace

Source: Frontiers in Neurology, Vol 14 (2023)

Subject Terms: neuromyelitis optica, relapse, eculizumab, AQP4, HRQoL – health-related quality of life, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2023.1099376/full; https://doaj.org/toc/1664-2295

Access URL: https://doaj.org/article/7dcd6b20c6ed44b39cb3c1f119ab5c3b

The Acute Optic Neuritis Network (ACON): Study protocol of a non-interventional prospective multicenter study on diagnosis and treatment of acute optic neuritis

Authors: Susanna Asseyer, Nasrin Asgari, Jeffrey Bennett, Omer Bialer, Yolanda Blanco, Francesca Bosello, Anna Camos-Carreras, Edgar Carnero Contentti, Sara Carta, John Chen, Claudia Chien, Mashina Chomba, Russell C. Dale, Josep Dalmau, Kristina Feldmann, Eoin P. Flanagan, Caroline Froment Tilikete, Carolina Garcia-Alfonso, Joachim Havla, Mark Hellmann, Ho Jin Kim, Philipp Klyscz, Frank Konietschke, Chiara La Morgia, Marco Lana-Peixoto, Maria Isabel Leite, Netta Levin, Michael Levy, Sara Llufriu, Pablo Lopez, Itay Lotan, Alessandra Lugaresi, Romain Marignier, Sara Mariotto, Susan P. Mollan, Cassandra Ocampo, Frederike Cosima Oertel, Maja Olszewska, Jacqueline Palace, Lekha Pandit, José Luis Peralta Uribe, Sean Pittock, Sudarshini Ramanathan, Natthapon Rattanathamsakul, Albert Saiz, Sara Samadzadeh, Bernardo Sanchez-Dalmau, Deanna Saylor, Michael Scheel, Tanja Schmitz-Hübsch, Jemal Shifa, Sasitorn Siritho, Pia S. Sperber, Prem S. Subramanian, Alon Tiosano, Adi Vaknin-Dembinsky, Alvaro Jose Mejia Vergara, Adi Wilf-Yarkoni, Luis Alfonso Zarco, Hanna G. Zimmermann, Friedemann Paul, Hadas Stiebel-Kalish

Source: Frontiers in Neurology, Vol 14 (2023)

Subject Terms: Aquaporin-4-IgG (AQP4-IgG), clinically isolated syndrome (CIS), MOG-IgG associated disorders (MOGAD), multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD), optic neuritis (ON), Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2023.1102353/full; https://doaj.org/toc/1664-2295

Access URL: https://doaj.org/article/5f9ad39795f54fbf9171a0e0c490d165

Patient-reported burden of myasthenia gravis: baseline results of the international prospective, observational, longitudinal real-world digital study MyRealWorld-MG

Authors: Jacqueline Palace, Kristl G Claeys, Renato Mantegazza, Andreas Meisel, Casey Quinn, Srikanth Muppidi, Hiroyuki Murai, Francesco Saccà, Sonia Berrih-Aknin, Sarah Dewilde, Mark Larkin, Jon Beauchamp, Sandra Paci, Laura Day, Glenn Philips, Silvia Chiroli, Guillaume Bassez, MF Janssen

Source: BMJ Open, Vol 13, Iss 1 (2023)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/13/1/e066445.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/89526dac77d5406291833a31dcc90782

Corrigendum: Determination of CSF GFAP, CCN5, and vWF levels enhances the diagnostic accuracy of clinically defined MS from non-MS patients with CSF oligoclonal bands

Authors: Fay Probert, Tianrong Yeo, Yifan Zhou, Megan Sealey, Siddharth Arora, Jacqueline Palace, Timothy D. W. Claridge, Rainer Hillenbrand, Johanna Oechtering, Jens Kuhle, David Leppert, Daniel C. Anthony

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: diagnosis, metabolomics (OMICS), multiple sclerosis (MS), proteomics, oligoclonal band, biomarker, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.1095038/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/75b59a542ce04643b4bcfa4d18406134

Sarcoidosis and neuromyelitis optica in a patient with optic neuritis – a case report

Authors: Michael A. Foster, Sara Collorone, Jacqueline Palace, James Acheson, Ahmed T. Toosy

Source: Annals of Clinical and Translational Neurology, Vol 8, Iss 8, Pp 1760-1763 (2021)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2328-9503

Access URL: https://doaj.org/article/02bf7cf85b1a44338b0331762eab1867

No strong HLA association with MOG antibody disease in the UK population

Authors: Melissa Grant‐Peters, Giordani Rodrigues Dos Passos, Hing‐Yuen Yeung, Anu Jacob, Saif Huda, Maria Isabel Leite, Calliope A. Dendrou, Jacqueline Palace

Source: Annals of Clinical and Translational Neurology, Vol 8, Iss 7, Pp 1502-1507 (2021)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2328-9503

Access URL: https://doaj.org/article/16214af920084e0ca70399c41e41bc06

State of the Art and Future Challenges in Multiple Sclerosis Research and Medical Management: An Insight into the 5th International Porto Congress of Multiple Sclerosis

Authors: María José Sá, Ricardo Soares dos Reis, Ayse Altintas, Elisabeth Gulowsen Celius, Claudia Chien, Giancarlo Comi, Francesc Graus, Jan Hillert, Jeremy Hobart, Gulfaraz Khan, Najib Kissani, Dawn Langdon, Maria Isabel Leite, Darin T. Okuda, Jacqueline Palace, Regina María Papais-Alvarenga, Inês Mendes-Pinto, Fu-Dong Shi

Source: Neurology and Therapy, Vol 9, Iss 2, Pp 281-300 (2020)

Subject Terms: Congress review, Demyelinating diseases, Multiple sclerosis, Neurological diseases, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2193-8253; https://doaj.org/toc/2193-6536

Access URL: https://doaj.org/article/65afe3297d014150a59b6a0b9ff8fb8b

Publisher Correction: Patient Pathway to Diagnosis of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD): Findings from a Multinational Survey of 204 Patients

Authors: Jonathan D. Santoro, Jennifer Gould, Zoya Panahloo, Ella Thompson, Julia Lefelar, Jacqueline Palace

Source: Neurology and Therapy, Vol 12, Iss 4, Pp 1103-1103 (2023)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2193-8253; https://doaj.org/toc/2193-6536

Access URL: https://doaj.org/article/1bdda9392ce642658e882e5026b1c45c

Determination of CSF GFAP, CCN5, and vWF Levels Enhances the Diagnostic Accuracy of Clinically Defined MS From Non-MS Patients With CSF Oligoclonal Bands

Authors: Fay Probert, Tianrong Yeo, Yifan Zhou, Megan Sealey, Siddharth Arora, Jacqueline Palace, Timothy D. W. Claridge, Rainer Hillenbrand, Johanna Oechtering, Jens Kuhle, David Leppert, Daniel C. Anthony

Source: Frontiers in Immunology, Vol 12 (2022)

Subject Terms: diagnosis, metabolomics (OMICS), multiple sclerosis (MS), proteomics, oligoclonal band, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.811351/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/b373569ef84b4d2cb68c28f8511163d9

Induction of aquaporin 4-reactive antibodies in Lewis rats immunized with aquaporin 4 mimotopes

Authors: Irina Tsymala, Magdalini Nigritinou, Bleranda Zeka, Rouven Schulz, Felix Niederschick, Mia Matković, Isabel J. Bauer, Michael Szalay, Kathrin Schanda, Magdalena Lerch, Tatsuro Misu, Kazuo Fujihara, Jeffrey L. Bennett, Charlotte Dahle, Florence Pache, Paulus Rommer, Fritz Leutmezer, Zsolt Illes, Maria Isabel Leite, Jacqueline Palace, Petra Scholze, Markus Reindl, Hans Lassmann, Monika Bradl

Source: Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)

Subject Terms: Neuromyelitis optica spectrum disorders, Antibodies, Mimotopes, Aquaporin 4, Infections, Animal model, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-020-00920-x; https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/31f94705aa8441cd9a1d41acfcb1be81