Anti-GPR56 monoclonal antibody potentiates GPR56-mediated Src-Fak signaling to modulate cell adhesion

Authors: Chatterjee, Treena, Zhang, Sheng, Posey, Tressie A., Jacob, Joan, Wu, Ling, Yu, Wangsheng, Francisco, Liezl E., Liu, Qingyun J., Carmon, Kendra S.

Source: In Journal of Biological Chemistry January-June 2021 296

RELA is sufficient to mediate interleukin‐1 repression of androgen receptor expression and activity in an LNCaP disease progression model

Authors: Thomas‐Jardin, Shayna E., Dahl, Haley, Kanchwala, Mohammed S., Ha, Freedom, Jacob, Joan, Soundharrajan, Reshma, Bautista, Monica, Nawas, Afshan F., Robichaux, Dexter, Mistry, Ragini, Anunobi, Vanessa, Xing, Chao, Delk, Nikki A.

Source: Prostate. 80(2):133-145

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100095910267.0x000001&indx=1&recIds=ETOCvdc_100095910267.0x000001

G protein selectivity profile of GPR56/ADGRG1 and its effect on downstream effectors.

Authors: Jallouli, Raida, Moreno-Salinas, Ana L., Laniel, Andréanne, Holleran, Brian, Avet, Charlotte, Jacob, Joan, Hoang, Trang, Lavoie, Christine, Carmon, Kendra S., Bouvier, Michel, Leduc, Richard

Source: Cellular & Molecular Life Sciences; 9/4/2024, Vol. 81 Issue 1, p1-18, 18p

Subject Terms: G proteins, LIGANDS (Biochemistry), TRAFFIC signs & signals, CANCER cells, BREAST cancer, G protein coupled receptors

Antitumor Activity of a Pyrrolobenzodiazepine Antibody–Drug Conjugate Targeting LGR5 in Preclinical Models of Neuroblastoma.

Authors: Tu, Jianghua, Toh, Yukimatsu, Aldana, Adela M., Wen, Jake J., Wu, Ling, Jacob, Joan, Li, Li, Pan, Sheng, Carmon, Kendra S., Liu, Qingyun J.

Source: Pharmaceutics; Jul2024, Vol. 16 Issue 7, p943, 13p

Subject Terms: GASTROINTESTINAL cancer, PERIPHERAL nervous system, CHILD death, METASTASIS, CYTOTOXINS, G protein coupled receptors

The Evolving Paradigm of Antibody–Drug Conjugates Targeting the ErbB/HER Family of Receptor Tyrosine Kinases.

Authors: High, Peyton, Guernsey, Cara, Subramanian, Shraddha, Jacob, Joan, Carmon, Kendra S.

Source: Pharmaceutics; Jul2024, Vol. 16 Issue 7, p890, 33p

Subject Terms: DRUG receptors, BISPECIFIC antibodies, COMBINATION drug therapy, PROTEIN-tyrosine kinases, PROTEIN-tyrosine kinase inhibitors, EPIDERMAL growth factor receptors

Air–Fluid level in the chest X-Ray after pneumonectomy

Authors: Moleyar, Vishnu, Jacob, Joan

Source: Journal of Advanced Lung Health. 3(2):66-67

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185430899.0x000001&indx=1&recIds=ETOCvdc_100185430899.0x000001

Chest radiology in a COVID patient with hypoxia

Authors: Sharma, M, Jacob, Joan

Source: Journal of Advanced Lung Health. 2(2):78-79

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100151545866.0x000001&indx=1&recIds=ETOCvdc_100151545866.0x000001

An antibody–drug conjugate targeting GPR56 demonstrates efficacy in preclinical models of colorectal cancer.

Authors: Jacob, Joan¹ (AUTHOR), Francisco, Liezl E.¹ (AUTHOR), Chatterjee, Treena¹ (AUTHOR), Liang, Zhengdong¹ (AUTHOR), Subramanian, Shraddha¹ (AUTHOR), Liu, Qingyun J.¹ (AUTHOR), Rowe, Julie H.² (AUTHOR), Carmon, Kendra S.¹ (AUTHOR) Kendra.S.Carmon@uth.tmc.edu

Source: British Journal of Cancer. Apr2023, Vol. 128 Issue 8, p1592-1602. 11p.

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Drug Conjugates of Antagonistic R-Spondin 4 Mutant for Simultaneous Targeting of Leucine-Rich Repeat-Containing G Protein-Coupled Receptors 4/5/6 for Cancer Treatment

Authors: Cui, Jie, Toh, Yukimatsu, Park, Soohyun, Yu, Wangsheng, Tu, Jianghua, Wu, Ling, Li, Li, Jacob, Joan, Pan, Sheng, Carmon, Kendra S., Liu, Qingyun J.

Source: Journal of Medicinal Chemistry; September 2021, Vol. 64 Issue: 17 p12572-12581, 10p

Viral Infections and Cell-Mediated Immunity in Immunodeficient Homosexual Men with Kaposi's Sarcoma Treated with Human Lymphoblastoid Interferon

Authors: Frederick, Winston R., Epstein, Jay S., Gelmann, Edward P., Rook, Alain H., Armstrong, Gary R., Djeu, Julie Y., Jackson, Lozannie, Manischewitz, Jody F., Enterline, Joan, Jacob, Joan, Masur, Henry, Quinnan, Gerald V.

Source: The Journal of Infectious Diseases, 1985 Jul 01. 152(1), 162-170.

Access URL: https://www.jstor.org/stable/30104652

Interferon-Induced 2'-5' Oligoadenylate Synthetase during Interferon-α Therapy in Homosexual Men with Kaposi's Sarcoma: Marked Deficiency in Biochemical Response to Interferon in Patients with Acquired Immunodeficiency Syndrome

Authors: Preble, Olivia T., Rook, Alain H., Steis, Ronald, Silverman, Robert H., Krause, David, Quinnan, Gerald V., Masur, Henry, Jacob, Joan, Longo, Dan, Gelmann, Edward P.

Source: The Journal of Infectious Diseases, 1985 Sep 01. 152(3), 457-465.

Access URL: https://www.jstor.org/stable/30105300

PROVIDING 'SAFE CONDUCT'--HELPING YOUR PATIENT COPE WITH CANCER.

Authors: Ostchega, Yechiam, Jacob, Joan Graetz

Source: Nursing. Apr84, Vol. 14 Issue 4, p42-47. 6p.

Subject Terms: *CANCER patients, *NURSE-patient relationships, *CARING

The Hippo Pathway in Cardiac Regeneration and Homeostasis: New Perspectives for Cell-Free Therapy in the Injured Heart.

Authors: Zheng, Mingjie¹ (AUTHOR) Mingjie.Zheng@uth.tmc.edu, Jacob, Joan² (AUTHOR) Joan.Jacob@uth.tmc.edu, Hung, Shao-Hsi² (AUTHOR) Shao-Hsi.Hung@uth.tmc.edu, Wang, Jun¹ (AUTHOR) Jun.Wang@uth.tmc.edu

Source: Biomolecules (2218-273X). Jul2020, Vol. 10 Issue 7, p1024. 1p.

Subject Terms: *CARDIAC regeneration, *HOMEOSTASIS, *HEART, *CELL proliferation, *CHROMATIN, *CARDIOVASCULAR diseases, *HEART cells

Identification of an IL‐1‐induced gene expression pattern in AR⁺ PCa cells that mimics the molecular phenotype of AR⁻ PCa cells.

Authors: Thomas‐Jardin, Shayna E., Kanchwala, Mohammed S., Jacob, Joan, Merchant, Sana, Meade, Rachel K., Gahnim, Nagham M., Nawas, Afshan F., Xing, Chao, Delk, Nikki A.

Source: Prostate; Jun2018, Vol. 78 Issue 8, p595-606, 12p

Molecules and models : investigations on the axiomatization of structure theory in chemistry.

Authors: Mulckhuyse, J. J. (Jacob Joan)

Access URL: http://hdl.handle.net/2027/umn.31951000930014l

Molecules and models investigations on the axiomatization of st...

Authors: Mulckhuyse, J. J. (Jacob Joan)

Access URL: http://hdl.handle.net/2027/uc1.b2666840

Chest Radiology in a COVID Patient with Hypoxia.

Authors: M., Vishnu Sharma, Jacob, Joan Jerry

Source: Journal of Advanced Lung Health; May-Aug2022, Vol. 2 Issue 2, p78-79, 2p

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