Tranexamic Acid for reduction of intra- and postoperative TRansfusion requirements in elective Abdominal surgery (TATRA): study protocol for an investigator-initiated, multicenter, double-blind, placebo-controlled, randomized superiority trial with two parallel groups

Authors: Ulrich Ronellenfitsch, Anita Kestel, Johannes Klose, Artur Rebelo, Michael Bucher, Daniel Ebert, Rafael Mikolajczyk, Andreas Wienke, Thomas Kegel, Julian Hering, Christian Haiduk, Michael Richter, Jörg Steighardt, Erich Grohmann, Lutz Otto, Jörg Kleeff

Source: Trials, Vol 25, Iss 1, Pp 1-12 (2024)

Subject Terms: Tranexamic acid, Abdominal surgery, Perioperative bleeding, Blood transfusion, Patient blood management, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1745-6215

Access URL: https://doaj.org/article/7b8f356fa8564f9d86b01a9b7cdb735d

Gene expression dynamics in fibroblasts during early-stage murine pancreatic carcinogenesis

Authors: Nupur Ohri, Johanna Häußler, Nino Javakhishvili, David Vieweg, Anais Zourelidis, Bogusz Trojanowicz, Monika Haemmerle, Irene Esposito, Markus Glaß, Yoshiaki Sunami, Jörg Kleeff

Source: iScience, Vol 28, Iss 1, Pp 111572- (2025)

Subject Terms: Biological sciences, Genetics, Cancer, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004224027998; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/7cbd1f19ad34437a8a429c5becc2a0de

Distance-depending transcriptome changes of pancreatic stellate cells in paracrine pancreatic ductal adenocarcinoma co-culture models

Authors: Anais Zourelidis, Bogusz Trojanowicz, Yoshiaki Sunami, Gerd Hause, David Vieweg, Jörg Kleeff

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/f1f8916a50834787be736600dc324404

Pancreatic cancer cell- and cancer-associated fibroblast-derived exosomes in disease progression, metastasis, and therapy

Authors: Yijun Chen, Jörg Kleeff, Yoshiaki Sunami

Source: Discover Oncology, Vol 15, Iss 1, Pp 1-10 (2024)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2730-6011

Access URL: https://doaj.org/article/01d55d8cfb0b4148871867ed5ea4b8db

Predictive parameters for early detection of clinically relevant abdominal trauma in multiple-injury or polytraumatised patients: a retrospective analysis

Authors: Stefan Fabig, Nadja Weigert, Filippo Migliorini, Jörg Kleeff, Gunther Olaf Hofmann, Philipp Schenk, Peter Hilbert-Carius, Philipp Kobbe, Thomas Mendel

Source: European Journal of Medical Research, Vol 29, Iss 1, Pp 1-12 (2024)

Subject Terms: Polytrauma, Bowel and mesenteric injury, Parenchymatous injury, Computed tomography, Laboratory parameters, Predictive parameters, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2047-783X

Access URL: https://doaj.org/article/ca701984511d422c9c3c3945272b2004

Methodology for Measuring Intraoperative Blood Loss: Protocol for a Scoping Review

Authors: Lätitia Dennin, Jörg Kleeff, Johannes Klose, Ulrich Ronellenfitsch, Artur Rebelo

Source: JMIR Research Protocols, Vol 13, p e58022 (2024)

Subject Terms: Medicine, Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://www.researchprotocols.org/2024/1/e58022; https://doaj.org/toc/1929-0748

Access URL: https://doaj.org/article/d041dad6cd214a229adae480b9c9f3c0

How to Reduce Delayed Gastric Emptying After Pancreatoduodenectomy: A Systematic Literature Review and Meta-Analysis

Authors: Artur Rebelo, MD, Randi Kresse, Yoshiaki Sunami, PhD, Ulrich Ronellenfitsch, MD, Jörg Kleeff, MD, Johannes Klose, MD

Source: Annals of Surgery Open, Vol 5, Iss 3, p e458 (2024)

Subject Terms: Surgery, RD1-811

File Description: electronic resource

Relation: http://journals.lww.com/10.1097/AS9.0000000000000458; https://doaj.org/toc/2691-3593

Access URL: https://doaj.org/article/fa5169d602d04511a073e714a067d1b2

Multivisceral Oncological Resections Involving the Pancreas: Protocol for a Systematic Review and Meta-Analysis

Authors: Melina Neuhaus, Juliane Friedrichs, Maurizio Grilli, Jörg Ukkat, Johannes Klose, Ulrich Ronellenfitsch, Jörg Kleeff, Artur Rebelo

Source: JMIR Research Protocols, Vol 13, p e54089 (2024)

Subject Terms: Medicine, Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://www.researchprotocols.org/2024/1/e54089; https://doaj.org/toc/1929-0748

Access URL: https://doaj.org/article/ab3bc532cfd84d2c84b0671cfe9c409d

Periostin is associated with prognosis and immune cell infiltration in pancreatic adenocarcinoma based on integrated bioinformatics analysis

Authors: Yijun Chen, Fengyu Zhang, Bolin Zhang, Bogusz Trojanowicz, Monika Hämmerle, Jörg Kleeff, Yoshiaki Sunami

Source: Cancer Reports, Vol 7, Iss 2, Pp n/a-n/a (2024)

Subject Terms: bioinformatics, cancer‐associated fibroblasts, pancreatic cancer, periostin, tumor‐associated macrophages, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2573-8348

Access URL: https://doaj.org/article/83c6cda3760144b5987c4eed8cf60852

Analysis of genomic alterations in cancer associated human pancreatic stellate cells

Authors: Viktoria Böker, Johanna Häußler, Jenny Baumann, Yoshiaki Sunami, Bogusz Trojanowicz, Bernadette Harwardt, Kathrin Hammje, Nadine von Auw, Mert Erkan, Knut Krohn, Jörg Kleeff

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/16271a43d11d4284b880d6cd52fabe1c

Acute and chronic mesenteric ischemia: single center analysis of open, endovascular, and hybrid surgery

Authors: Artur Rebelo, Marat Mammadov, Jumber Partsakhashvili, Carsten Sekulla, Ulrich Ronellenfitsch, Jörg Kleeff, Endres John, Jörg Ukkat

Source: BMC Surgery, Vol 22, Iss 1, Pp 1-7 (2022)

Subject Terms: Mesenteric ischemia, Open surgery, Endovascular surgery, Hybrid surgery, Surgery, RD1-811

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2482

Access URL: https://doaj.org/article/4fb4489d9e0c4259b5048566361d15a4

Is it feasible and ethical to randomize patients between surgery and non-surgical treatments for gastrointestinal cancers?

Authors: Artur Rebelo, Johannes Klose, Jörg Kleeff, Ulrich Ronellenfitsch

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: cancer, randomized control trial (RCT), ethical, gastrointestinal, oncology, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1119436/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/435fa6099475401a95a1e4f6465d281f

Postoperative Sigmoidoscopy and Biopsy After Elective Endovascular and Open Aortic Surgery for Preventing Mortality by Colonic Ischemia (PSB-Aorta-CI): Protocol for a Prospective Study

Authors: Artur Rebelo, Ulrich Ronellenfitsch, Jumber Partsakhashvili, Endres John, Carsten Sekulla, Sebastian Krug, Jonas Rosendahl, Patrick Michl, Jörg Ukkat, Jörg Kleeff

Source: JMIR Research Protocols, Vol 11, Iss 12, p e39071 (2022)

Subject Terms: Medicine, Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://www.researchprotocols.org/2022/12/e39071; https://doaj.org/toc/1929-0748

Access URL: https://doaj.org/article/5d0807eb848540b49869b02830011a90

Identification of prognostic lipid droplet-associated genes in pancreatic cancer patients via bioinformatics analysis

Authors: Rubing Bai, Artur Rebelo, Jörg Kleeff, Yoshiaki Sunami

Source: Lipids in Health and Disease, Vol 20, Iss 1, Pp 1-12 (2021)

Subject Terms: Bioinformatics, GEPIA, Lipid droplet-associated genes, Pancreatic cancer, Lipid metabolism, Nutritional diseases. Deficiency diseases, RC620-627

File Description: electronic resource

Relation: https://doaj.org/toc/1476-511X

Access URL: https://doaj.org/article/9225d3900fab48e49a03ca1d768ee036

Surgical Oncology: Multidisciplinarity to Improve Cancer Treatment and Outcomes

Authors: Jörg Kleeff, Ulrich Ronellenfitsch

Source: Current Oncology, Vol 28, Iss 6, Pp 4471-4473 (2021)

Subject Terms: n/a, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.mdpi.com/1718-7729/28/6/379; https://doaj.org/toc/1198-0052; https://doaj.org/toc/1718-7729

Access URL: https://doaj.org/article/df60906009774533a7614ec03f6faa07

A multilayered post-GWAS assessment on genetic susceptibility to pancreatic cancer

Authors: Evangelina López de Maturana, Juan Antonio Rodríguez, Lola Alonso, Oscar Lao, Esther Molina-Montes, Isabel Adoración Martín-Antoniano, Paulina Gómez-Rubio, Rita Lawlor, Alfredo Carrato, Manuel Hidalgo, Mar Iglesias, Xavier Molero, Matthias Löhr, Christopher Michalski, José Perea, Michael O’Rorke, Victor Manuel Barberà, Adonina Tardón, Antoni Farré, Luís Muñoz-Bellvís, Tanja Crnogorac-Jurcevic, Enrique Domínguez-Muñoz, Thomas Gress, William Greenhalf, Linda Sharp, Luís Arnes, Lluís Cecchini, Joaquim Balsells, Eithne Costello, Lucas Ilzarbe, Jörg Kleeff, Bo Kong, Mirari Márquez, Josefina Mora, Damian O’Driscoll, Aldo Scarpa, Weimin Ye, Jingru Yu, PanGenEU Investigators, Montserrat García-Closas, Manolis Kogevinas, Nathaniel Rothman, Debra T Silverman, SBC/EPICURO Investigators, Demetrius Albanes, Alan A Arslan, Laura Beane-Freeman, Paige M Bracci, Paul Brennan, Bas Bueno-de-Mesquita, Julie Buring, Federico Canzian, Margaret Du, Steve Gallinger, J Michael Gaziano, Phyllis J Goodman, Marc Gunter, Loic LeMarchand, Donghui Li, Rachael E Neale, Ulrika Peters, Gloria M Petersen, Harvey A Risch, Maria José Sánchez, Xiao-Ou Shu, Mark D Thornquist, Kala Visvanathan, Wei Zheng, Stephen J Chanock, Douglas Easton, Brian M Wolpin, Rachael Z Stolzenberg-Solomon, Alison P Klein, Laufey T Amundadottir, Marc A Marti-Renom, Francisco X Real, Núria Malats

Source: Genome Medicine, Vol 13, Iss 1, Pp 1-18 (2021)

Subject Terms: Pancreatic cancer risk, Genome-wide association analysis, Genetic susceptibility, 3D genomic structure, Local indices of genome spatial autocorrelation, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/fd82873a71df49c79bdc3dadb14c043b

Management of an abdominal penetration injury due to a car accident

Authors: Niels Michael Dörr, Ingo Wiesner, Jörg Kleeff

Source: Trauma Case Reports, Vol 39, Iss , Pp 100646- (2022)

Subject Terms: Damage control surgery, Penetrating trauma, Abdominal trauma, Abdominal wall reconstruction, Surgery, RD1-811

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352644022000425; https://doaj.org/toc/2352-6440

Access URL: https://doaj.org/article/f3457158c6f1400a9525a1d0edb2055b

Lymph Node Yield in Gastrointestinal Cancer Surgery With or Without Prior Neoadjuvant Therapy: Protocol for a Systematic Review and Meta-analysis

Authors: Ulrich Ronellenfitsch, Nika Mathis, Juliane Friedrichs, Jörg Kleeff

Source: JMIR Research Protocols, Vol 11, Iss 4, p e35243 (2022)

Subject Terms: Medicine, Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://www.researchprotocols.org/2022/4/e35243; https://doaj.org/toc/1929-0748

Access URL: https://doaj.org/article/b2600a3d1bff4fae99ab4049057e9832

Interventions to reduce the incidence of surgical site infection in colorectal resections: systematic review with multicomponent network meta-analysis (INTRISSI): study protocol

Authors: Jörg Kleeff, Christoph W Michalski, Ulrich Ronellenfitsch, Juliane Friedrichs, Svenja Seide, Johannes Vey, Samuel Zimmermann, Julia Hardt, Johannes Klose, Meinhard Kieser, Maximilian Pilz

Source: BMJ Open, Vol 11, Iss 11 (2021)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/11/11/e057226.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/288ab1f813434e5f888eb3e5b34600e3

Surgery With Arterial Resection for Hilar Cholangiocarcinoma: Protocol for a Systematic Review and Meta-analysis

Authors: Artur Rebelo, Jörg Ukkat, Johannes Klose, Ulrich Ronellenfitsch, Jörg Kleeff

Source: JMIR Research Protocols, Vol 10, Iss 10, p e31212 (2021)

Subject Terms: Medicine, Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://www.researchprotocols.org/2021/10/e31212; https://doaj.org/toc/1929-0748

Access URL: https://doaj.org/article/321d530767b4476c9d3a0fbcb7c193d3