Diagnostic impact of DNA methylation classification in adult and pediatric CNS tumors

Authors: Laetitia Lebrun, Nathalie Gilis, Manon Dausort, Chloé Gillard, Stefan Rusu, Karim Slimani, Olivier De Witte, Fabienne Escande, Florence Lefranc, Nicky D’Haene, Claude Alain Maurage, Isabelle Salmon

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-14 (2025)

Subject Terms: DNA methylation, Neuropathology, CNS tumor, Pediatric CNS tumors, Next generation sequencing, DKFZ classifier, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/4def4ad9aa7549f598bb82420abc6083

Inverse correlation between the amounts of lymphocytic infiltrate and stroma in breast carcinoma

Authors: Camille Verocq, Jean-Christophe Noël, Manon Charry, Egor Zindy, Sandrine Rorive, Isabelle Salmon, Christine Decaestecker, Xavier Catteau

Source: Heliyon, Vol 10, Iss 22, Pp e40295- (2024)

Subject Terms: Breast carcinoma, Intratumoural lymphocytes, Lymphocytic infiltrate, Peritumoural lymphocytes, TSR, Tumour stroma, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024163268; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/c33b8ca817cd4db7a1eecebd34874f80

Validation of a targeted next-generation sequencing panel for pancreatic ductal adenocarcinomas

Authors: Marie-Lucie Racu, Andrea Alex Schiavo, Claude Van Campenhout, Nancy De Nève, Thomas Masuy, Calliope Maris, Christine Decaestecker, Myriam Remmelink, Isabelle Salmon, Nicky D'Haene

Source: Experimental and Molecular Pathology, Vol 139, Iss , Pp 104920- (2024)

Subject Terms: Pancreatic ductal adenocarcinoma (PDAC), Next-generation sequencing (NGS), Copy number alteration (CNA), Chromosome 18 loss of heterozygosity (LOH), Pathology, RB1-214

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S001448002400039X; https://doaj.org/toc/1096-0945

Access URL: https://doaj.org/article/60caf256d47f4ab1a2308a8d5e394c37

Autonomously functioning thyroid nodules present intermediate malignancy risk according to European Thyroid Imaging Reporting and Data System (EU-TIRADS) and yield indeterminate cytology results

Authors: Aglaia Kyrilli, Nunzia Tacelli, Lucia Russo, Laetitia Lebrun, Isabelle Salmon, Gilles Russ, Rodrigo Moreno-Reyes, Bernard Corvilain

Source: European Thyroid Journal, Vol 12, Iss 6, Pp 1-9 (2023)

Subject Terms: autonomously functioning thyroid nodules, ultrasound, thyroid cancer, cytology, scintigraphy, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://etj.bioscientifica.com/view/journals/etj/12/6/ETJ-23-0135.xml; https://doaj.org/toc/2235-0802

Access URL: https://doaj.org/article/1fe653b422d44cb7ba7526937d8e5515

Usefulness of FAPα assessment in bronchoalveolar lavage as a marker of fibrogenesis: results of a preclinical study and first report in patients with idiopathic pulmonary fibrosis

Authors: Philomène Lavis, Julien Pingitore, Gilles Doumont, Ani Garabet, Gaetan Van Simaeys, Simon Lacroix, Nicolas Passon, Christophe Van Heymbeek, Coraline De Maeseneire, Justine Allard, Amandine Collin, François Huaux, Christine Decaestecker, Isabelle Salmon, Serge Goldman, Alessandra Kupper Cardozo, Benjamin Bondue

Source: Respiratory Research, Vol 24, Iss 1, Pp 1-13 (2023)

Subject Terms: Idiopathic pulmonary fibrosis, Fibroblast activation protein, Bronchoalveolar lavage, FAPI, PET scan, Biomarker, Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: https://doaj.org/toc/1465-993X

Access URL: https://doaj.org/article/ed142acb536f4c96bffc9e6065b02936

Childhood craniopharyngioma: a retrospective study of children followed in Hôpital Universitaire de Bruxelles

Authors: Clémentine Magerman, Emese Boros, Marco Preziosi, Sophie Lhoir, Nathalie Gilis, Olivier De Witte, Claudine Heinrichs, Isabelle Salmon, Christophe Fricx, Françoise Vermeulen, Laetitia Lebrun, Cécile Brachet, Marine Rodesch

Source: Frontiers in Endocrinology, Vol 15 (2024)

Subject Terms: childhood craniopharyngioma, neurosurgery, radiotherapy, hypothalamic obesity, endocrine disorders, visual disorders, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2024.1297132/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/3395c87c732d41eeb941af31c00448cb

Radiological characterization of pediatric intramedullary astrocytomas: Do they differ from adults?

Authors: Nathalie Gilis, Laetitia Lebrun, Valentina Lolli, Philippe David, Marine Rodesch, Alix Bex, Christophe Fricx, Vivianne De Maertelaer, Isabelle Salmon, Olivier De Witte

Source: Brain and Spine, Vol 4, Iss , Pp 102671- (2024)

Subject Terms: Intramedullary astrocytoma, Pediatric spinal cord tumor, Pilocytic astrocytoma, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772529423009591; https://doaj.org/toc/2772-5294

Access URL: https://doaj.org/article/96d2655dbecf449495510fe88674e74a

SARS-Cov-2 infection and neuropathological findings: a report of 18 cases and review of the literature

Authors: Laetitia Lebrun, Lara Absil, Myriam Remmelink, Ricardo De Mendonça, Nicky D’Haene, Nicolas Gaspard, Stefan Rusu, Marie-Lucie Racu, Amandine Collin, Justine Allard, Egor Zindy, Andrea Alex Schiavo, Sarah De Clercq, Olivier De Witte, Christine Decaestecker, Maria-Beatriz Lopes, Isabelle Salmon

Source: Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-17 (2023)

Subject Terms: SARS-CoV-2, COVID-19, PCR, Postmortem procedure, Immunohistochemistry, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/0063eb97775a4c629d1ab928ec3cb66c

Clinicopathological and molecular characterization of a case classified by DNA‑methylation profiling as 'CNS embryonal tumor with BRD4–LEUTX fusion'

Authors: Laetitia Lebrun, Sacha Allard-Demoustiez, Nathalie Gilis, Claude Van Campenhout, Marine Rodesch, Celine Roman, Pierluigi Calò, Valentina Lolli, Philippe David, Christophe Fricx, Olivier De Witte, Fabienne Escande, Claude-Alain Maurage, Isabelle Salmon

Source: Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-7 (2023)

Subject Terms: Brain tumor, CNS embryonal tumor, DNA methylation, H3K27me3 protein expression, BRD4, LEUTX, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/a7e8b77961374116afca9f04379b01e9

Comparison Between Manual and Automated Assessment of Ki-67 in Breast Carcinoma: Test of a Simple Method in Daily Practice

Authors: Xavier Catteau MD, PhD, Egor Zindy PhD, Sarah Bouri MD, Jean-Christophe Noël MD, PhD, Isabelle Salmon MD, PhD, Christine Decaestecker PhD

Source: Technology in Cancer Research & Treatment, Vol 22 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1533-0338

Access URL: https://doaj.org/article/46f2061f9f984d21a8a84b1384847dc1

Correction: VEGFR1 and VEGFR2 Involvement in Extracellular Galectin-1- and Galectin-3-Induced Angiogenesis.

Authors: Nicky D'Haene, Sébastien Sauvage, Calliope Maris, Ivan Adanja, Marie Le Mercier, Christine Decaestecker, Linda Baum, Isabelle Salmon

Source: PLoS ONE, Vol 18, Iss 12, p e0295736 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0295736&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/6a0d4ec1d69a491c983bbdbce1bfb968

Initial Condition Assessment for Reaction-Diffusion Glioma Growth Models: A Translational MRI-Histology (In)Validation Study

Authors: Corentin Martens, Laetitia Lebrun, Christine Decaestecker, Thomas Vandamme, Yves-Rémi Van Eycke, Antonin Rovai, Thierry Metens, Olivier Debeir, Serge Goldman, Isabelle Salmon, Gaetan Van Simaeys

Source: Tomography, Vol 7, Iss 4, Pp 650-674 (2021)

Subject Terms: cellularity, digital pathology, glioma, histology, magnetic resonance imaging, reaction-diffusion model, Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://www.mdpi.com/2379-139X/7/4/55; https://doaj.org/toc/2379-1381; https://doaj.org/toc/2379-139X

Access URL: https://doaj.org/article/02b74fec94b3407b81533beeee94a801

Chemerin plasma levels are increased in COVID-19 patients and are an independent risk factor of mortality

Authors: Philomène Lavis, Sofia Morra, Carmen Orte Cano, Nurhan Albayrak, Véronique Corbière, Véronique Olislagers, Nicolas Dauby, Véronique Del Marmol, Arnaud Marchant, Christine Decaestecker, Françoise Mascart, Nathalie De Vos, Philippe Van de Borne, Isabelle Salmon, Myriam Remmelink, Marc Parmentier, Alessandra Kupper Cardozo, Benjamin Bondue

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: COVID-19, chemerin, ChemR23, CMKLR1, survival, ARDS, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.941663/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/82fabf54a5494ca4abcea9a910de8d4e

Clinical, radiological and molecular characterization of intramedullary astrocytomas

Authors: Laetitia Lebrun, Barbara Meléndez, Oriane Blanchard, Nancy De Nève, Claude Van Campenhout, Julie Lelotte, Danielle Balériaux, Matteo Riva, Jacques Brotchi, Michaël Bruneau, Olivier De Witte, Christine Decaestecker, Nicky D’Haene, Isabelle Salmon

Source: Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-14 (2020)

Subject Terms: Intramedullary astrocytomas-glial tumor-spinal cord-targeted next-generation sequencing-H3F3A K27M-KIAA1549-BRAF, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-020-00962-1; https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/2878ed91c2794ea0bf4331c5ccf2193b

Unspecific post-mortem findings despite multiorgan viral spread in COVID-19 patients

Authors: Myriam Remmelink, Ricardo De Mendonça, Nicky D’Haene, Sarah De Clercq, Camille Verocq, Laetitia Lebrun, Philomène Lavis, Marie-Lucie Racu, Anne-Laure Trépant, Calliope Maris, Sandrine Rorive, Jean-Christophe Goffard, Olivier De Witte, Lorenzo Peluso, Jean-Louis Vincent, Christine Decaestecker, Fabio Silvio Taccone, Isabelle Salmon

Source: Critical Care, Vol 24, Iss 1, Pp 1-10 (2020)

Subject Terms: COVID-19, SARS-CoV-2, Autopsy, RT-PCR, Immunohistochemistry, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13054-020-03218-5; https://doaj.org/toc/1364-8535

Access URL: https://doaj.org/article/978a832615f44b4db34ea1501648bc10

Case Report: Interest of Positron Emission Tomography in Pediatric Small Vessel Primary Angiitis of the Central Nervous System

Authors: Morgane Belcour, Pauline Dontaine, Anne Monier, Laetitia Lebrun, Isabelle Salmon, Olivier De Witte, Serge Goldman, Xavier De Tiège, Alec Aeby

Source: Frontiers in Pediatrics, Vol 10 (2022)

Subject Terms: primary angiitis of central nervous system, positron emission tomography (PET), cerebral vasculitis, magnetic resonance imaging (MRI), brain biopsy, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fped.2022.794294/full; https://doaj.org/toc/2296-2360

Access URL: https://doaj.org/article/95af7b6038ff478aafbf268a00763d95

Intracerebral administration of CTLA-4 and PD-1 immune checkpoint blocking monoclonal antibodies in patients with recurrent glioblastoma: a phase I clinical trial

Authors: Mark Kockx, Bart Neyns, Julia Katharina Schwarze, Gil Awada, Laura Seynaeve, Anne-Marie Vanbinst, Alex Michotte, Hendrik Everaert, Johnny Duerinck, Ramses Forsyth, Jens Tijtgat, Freya Vaeyens, Cleo Bertels, Wietse Geens, Samuel Klein, Louise Cras, Nicky D’Haene, Ben Caljon, Isabelle Salmon, Michaël Bruneau, Sonia Van Dooren

Source: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/9/6/e002296.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/3ba763cd5ca7402e845d3c9a49fd3c50

Neoadjuvant degarelix with or without apalutamide followed by radical prostatectomy for intermediate and high-risk prostate cancer: ARNEO, a randomized, double blind, placebo-controlled trial

Authors: Lorenzo Tosco, Annouschka Laenen, Thomas Gevaert, Isabelle Salmon, Christine Decaestecker, Elai Davicioni, Christine Buerki, Frank Claessens, Johan Swinnen, Karolien Goffin, Raymond Oyen, Wouter Everaerts, Lisa Moris, Gert De Meerleer, Karin Haustermans, Steven Joniau, P.E.A.R.L. (ProstatE cAncer Research Leuven)

Source: BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-018-4275-z; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/d756a2c91f6b4917b75eee73727709ee

CDK4 phosphorylation status and a linked gene expression profile predict sensitivity to palbociclib

Authors: Eric Raspé, Katia Coulonval, Jaime M Pita, Sabine Paternot, Françoise Rothé, Laure Twyffels, Sylvain Brohée, Ligia Craciun, Denis Larsimont, Véronique Kruys, Flavienne Sandras, Isabelle Salmon, Steven Van Laere, Martine Piccart, Michail Ignatiadis, Christos Sotiriou, Pierre P Roger

Source: EMBO Molecular Medicine, Vol 9, Iss 8, Pp 1052-1066 (2017)

Subject Terms: CDK4/6 inhibitors, breast cancer, cyclin‐dependent kinase 4, PD0332991, sensitivity biomarker, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/9b2d45e7df5c4aa580875b12ef3ec949

The potential of tumour microenvironment markers to stratify the risk of recurrence in prostate cancer patients.

Authors: Thomas Gevaert, Yves-Rémi Van Eycke, Thomas Vanden Broeck, Hein Van Poppel, Isabelle Salmon, Sandrine Rorive, Tim Muilwijk, Frank Claessens, Dirk De Ridder, Steven Joniau, Christine Decaestecker

Source: PLoS ONE, Vol 15, Iss 12, p e0244663 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ec82bfb8bd3541ba89838661fe6c91c8