Repression of apelin Furin cleavage sites provides antimetastatic strategy in colorectal cancer

Authors: Béatrice Demoures, Fabienne Soulet, Jean Descarpentrie, Isabel Galeano-Otero, José Sanchez Collado, Maria Casado, Tarik Smani, Alvaro González, Isabel Alves, Fabrice Lalloué, Bernard Masri, Estelle Rascol, Jean-William Dupuy, Cyril Dourthe, Frédéric Saltel, Anne-Aurélie Raymond, Iker Badiola, Serge Evrard, Bruno Villoutreix, Simon Pernot, Géraldine Siegfried, Abdel-Majid Khatib

Source: EMBO Molecular Medicine, Vol 17, Iss 3, Pp 504-534 (2025)

Subject Terms: Apelin, Furin, Colon Cancer, Liver Metastasis, Safety Pharmacology, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/e863c4000fde414c8bab73098f746d4e

Sulconazole inhibits PD-1 expression in immune cells and cancer cells malignant phenotype through NF-κB and calcium activity repression

Authors: Simon Pernot, Mercedes Tomé, Isabel Galeano-Otero, Serge Evrard, Iker Badiola, Frederic Delom, Delphine Fessart, Tarik Smani, Geraldine Siegfried, Bruno O. Villoutreix, Abdel-Majid Khatib

Source: Frontiers in Immunology, Vol 14 (2024)

Subject Terms: PD-1, Jurkat T cells, PBMCs, NF-κB, calcium, cancer, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1278630/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/90571bd8e03445089bd4c69afb1017e6

Cardiac protection induced by urocortin-2 enables the regulation of apoptosis and fibrosis after ischemia and reperfusion involving miR-29a modulation

Authors: Isabel Mayoral-González, Eva M. Calderón-Sánchez, Isabel Galeano-Otero, Marta Martín-Bórnez, Encarnación Gutiérrez-Carretero, María Fernández-Velasco, Nieves Domenech, María Generosa Crespo-Leiro, Ana María Gómez, Antonio Ordóñez-Fernández, Abdelkrim Hmadcha, Tarik Smani

Source: Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 838-853 (2022)

Subject Terms: ischemia and reperfusion, miRNA, heart failure, apoptosis, fibrosis, Ucn-2, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253122000087; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/80b1b6ec2ec24c92bf07651ea1856b7a

Predicted Value of MicroRNAs, Vascular Endothelial Growth Factor, and Intermediate Monocytes in the Left Adverse Ventricular Remodeling in Revascularized ST-Segment Elevation Myocardial Infarction Patients

Authors: Raquel Del Toro, Isabel Galeano-Otero, Elisa Bevilacqua, Francisco Guerrero-Márquez, Debora Falcon, Agustín Guisado-Rasco, Luis Díaz-de la Llera, Gonzalo Barón-Esquivias, Tarik Smani, Antonio Ordóñez-Fernández

Source: Frontiers in Cardiovascular Medicine, Vol 9 (2022)

Subject Terms: STEMI, PPCI, inflammatory cells, monocytes, left ventricular adverse remodeling, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2022.777717/full; https://doaj.org/toc/2297-055X

Access URL: https://doaj.org/article/5e30ad1f82bb4e24a0a420338eb91d56

Corrigendum: SARAF and Orai1 Contribute to Endothelial Cell Activation and Angiogenesis

Authors: Isabel Galeano-Otero, Raquel del-Toro, Abdel-Majid Khatib, Juan Antonio Rosado, Antonio Ordóñez-Fernández, Tarik Smani

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: Orai1, SARAF, SOCE, HUVEC, angiogenesis, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.683097/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/0439388c52f94a6f84f374e41ac69c70

SARAF and Orai1 Contribute to Endothelial Cell Activation and Angiogenesis

Authors: Isabel Galeano-Otero, Raquel Del Toro, Abdel-Majid Khatib, Juan Antonio Rosado, Antonio Ordóñez-Fernández, Tarik Smani

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: Orai1, SARAF, SOCE, HUVEC, angiogenesis, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.639952/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/a209e74285db4c6e88cbe0052f99559f

TRP Channels: Current Perspectives in the Adverse Cardiac Remodeling

Authors: Debora Falcón, Isabel Galeano-Otero, Eva Calderón-Sánchez, Raquel Del Toro, Marta Martín-Bórnez, Juan A. Rosado, Abdelkrim Hmadcha, Tarik Smani

Source: Frontiers in Physiology, Vol 10 (2019)

Subject Terms: calcium, TRP channels, cardiac remodeling, hypertrophy, fibrosis, conduction disorders, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphys.2019.00159/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/feef09e17daf4f5f99ba75bacd422c7b

TRPC Channels: Dysregulation and Ca2+ Mishandling in Ischemic Heart Disease

Authors: Débora Falcón, Isabel Galeano-Otero, Marta Martín-Bórnez, María Fernández-Velasco, Isabel Gallardo-Castillo, Juan A. Rosado, Antonio Ordóñez, Tarik Smani

Source: Cells, Vol 9, Iss 1, p 173 (2020)

Subject Terms: trpc channel, ca2+ entry, cardiac infarction, cardiac repair, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/1/173; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/33c46d8de08e416994dd7849f8a2d236