Efficacy and safety of the neonatal Fc receptor inhibitor efgartigimod in adults with primary immune thrombocytopenia (ADVANCE IV): a multicentre, randomised, placebo-controlled, phase 3 trial

Authors: Fillitz, Michael, Knoebl, Paul, Meers, Stef, Amine, Ismail Mohamad, Gumulec, Jaromir, Hlusi, Antonin, Mayer, Jiri, Quittet, Philippe, Viallard, Jean-Francois, Betaneli, Magdana, Datikashvili-David, Irine, Iosava, Genadi, Makhaldiani, Levan, Rejto, Laszlo, Sharashenidze, Nino, Groepper, Stefanie, Röth, Alexander, Hamed, Aryan, Illes, Arpad, Carpenedo, Monica, Artoni, Andrea, Bocchia, Monica, Gamberi, Barbara, Borchiellini, Alessandra, Oliva, Esther Natalie, Patriarca, Andrea, Tomassetti, Simona, Miyakawa, Yoshitaka, Ando, Kiyoshi, Handa, Hiroshi, Katsutani, Shinya, Nishiwaki, Kaichi, Ito, Shoko, Ito, Tomoki, de Boer, Fransien, Jansen, A.J. Gerard, Ciepluch, Hanna, Fornagiel, Szymon, Grosicki, Sebastian, Soroka-Wojtaszko, Maria, Trelinski, Jacek, Bakirov, Bulat, Borisenkova, Elena, Volodicheva, Elena, Shatokhin, Yuri, Proydakov, Andrey, Alonso, Maria Aranzazu, Mingot-Castellano, María Eva, Sanchez-Gonzalez, Blanca, Valcarcel Ferreiras, David, Ayli, Meltem, Hacibekiroglu, Tuba, Demir, Ahmet Muzaffer, Nalçaci, Meliha, Sonmez, Mehmet, Tombak, Anil, Toprak, Selami Kocak, Turgut, Burhan, Vural, Filiz, Yagci, Munci, Altuntas, Fevzi, Turgut, Mehmet, Kaya, Emin, Romanyuk, Nataliya, McDonald, Vickie, Kazmi, Syed Rashid Saeed, Broome, Catherine, Cataland, Spero, Doshi, Ketan, Lentz, Steven R., Boxer, Michael, Rosenberg, Richard, Broome, Catherine M ^*, Kuter, David J, Al-Samkari, Hanny, Bussel, James B, Godar, Marie, Ayguasanosa, Jaume, De Beuf, Kristof, Rodeghiero, Francesco, Michel, Marc, Newland, Adrian

Source: In The Lancet 4-10 November 2023 402(10413):1648-1659

Daratumumab Plus Bortezomib, Melphalan, and Prednisone Versus Bortezomib, Melphalan, and Prednisone in Transplant-Ineligible Newly Diagnosed Multiple Myeloma: Frailty Subgroup Analysis of ALCYONE

Authors: Mateos, Maria-Victoria, Dimopoulos, Meletios A., Cavo, Michele, Suzuki, Kenshi, Knop, Stefan, Doyen, Chantal, Lucio, Paulo, Nagy, Zsolt, Pour, Ludek, Grosicki, Sebastian, Crepaldi, Andre, Liberati, Anna Marina, Campbell, Philip, Yoon, Sung-Soo, Iosava, Genadi, Fujisaki, Tomoaki, Garg, Mamta, Iida, Shinsuke, Bladé, Joan, Ukropec, Jon, Pei, Huiling, Van Rampelbergh, Rian, Kudva, Anupa, Qi, Ming, San-Miguel, Jesus

Source: In Clinical Lymphoma, Myeloma and Leukemia November 2021 21(11):785-798

Subcutaneous engineered factor VIIa marzeptacog alfa (activated) in hemophilia with inhibitors: Phase 2 trial of pharmacokinetics, pharmacodynamics, efficacy, and safety

Authors: Mahlangu, Johnny, Levy, Howard ^*, Kosinova, Marina V., Khachatryan, Heghine, Korczowski, Bartosz, Makhaldiani, Levani, Iosava, Genadi, Lee, Martin, Del Greco, Frank

Source: In Research and Practice in Thrombosis and Haemostasis August 2021 5(6)

Overall survival with daratumumab, bortezomib, melphalan, and prednisone in newly diagnosed multiple myeloma (ALCYONE): a randomised, open-label, phase 3 trial

Authors: Mateos, Maria-Victoria ^*, Cavo, Michele, Blade, Joan, Dimopoulos, Meletios A, Suzuki, Kenshi, Jakubowiak, Andrzej, Knop, Stefan, Doyen, Chantal, Lucio, Paulo, Nagy, Zsolt, Pour, Ludek, Cook, Mark, Grosicki, Sebastian, Crepaldi, Andre, Liberati, Anna Marina, Campbell, Philip, Shelekhova, Tatiana, Yoon, Sung-Soo, Iosava, Genadi, Fujisaki, Tomoaki, Garg, Mamta, Krevvata, Maria, Chen, Ying, Wang, Jianping, Kudva, Anupa, Ukropec, Jon, Wroblewski, Susan, Qi, Ming, Kobos, Rachel, San-Miguel, Jesus

Source: In The Lancet 11-17 January 2020 395(10218):132-141

Daratumumab Plus Bortezomib, Melphalan, and Prednisone (D-VMP) Versus Bortezomib, Melphalan, and Prednisone (VMP) Alone in Transplant-Ineligible Patients with Newly Diagnosed Multiple Myeloma (NDMM): Updated Analysis of the Phase 3 Alcyone Study

Authors: Mateos, Maria-Victoria, San-Miguel, Jesús, Cavo, Michele ^*, Bladé Creixenti, Joan, Suzuki, Kenshi, Jakubowiak, Andrzej, Knop, Stefan ^*, Doyen, Chantal, Lucio, Paulo ^*, Nagy, Zsolt ^*, Pour, Ludek ^*, Grosicki, Sebastian, Crepaldi, Andre H ^*, Liberati, Anna Marina, Campbell, Philip ^*, Shelekhova, Tatiana ^*, Yoon, Sung-Soo, Iosava, Genadi ^*, Fujisaki, Tomoaki ^*, Garg, Mamta ^*, Pei, Huiling ^*, Krevvata, Maria ^*, Carson, Robin, Borgsten, Fredrik ^*, Dimopoulos, Meletios A.

Source: In Blood 15 November 2022 140 Supplement 1:10157-10159

Efficacy, Safety and Pharmacokinetic Results of a Phase III, Open-Label, Multicenter Study with a Plasma-Derived Von Willebrand Factor (VWF)/Factor VIII (FVIII) Concentrate in Pediatric Patients <12 Years of Age with Hemophilia A (SWIFTLY-HA Study).

Authors: Khayat, Claudia Djambas (AUTHOR), Iosava, Genadi (AUTHOR), Romashevskaya, Irina (AUTHOR), Stasyshyn, Oleksandra (AUTHOR), Lopez, Marta Julia (AUTHOR), Pompa, Maria Teresa (AUTHOR), Rogosch, Tobias (AUTHOR), Seifert, Wilfried (AUTHOR)

Source: Journal of Blood Medicine. Jun2021, Vol. 12, p483-495. 13p.

Subject Terms: *VON Willebrand disease, *VON Willebrand factor, *CHILD patients, *BLOOD coagulation factor VIII, *PHARMACOKINETICS, *HEMOPHILIA, *DESMOPRESSIN

Pharmacokinetics, Efficacy and Safety of a Plasma-Derived VWF/FVIII Concentrate (Formulation V) in Pediatric Patients with von Willebrand Disease (SWIFTLY-VWD Study).

Authors: Auerswald, Guenter, Khayat, Claudia Djambas, Stasyshyn, Oleksandra, Iosava, Genadi, Romashevskaya, Irina, López, Marta Julia, Seifert, Wilfried, Rogosch, Tobias

Source: Journal of Blood Medicine; Jun2020, Vol. 11, p213-225, 13p

Subject Terms: VON Willebrand factor, PHARMACOKINETICS, ANAPHYLAXIS, VIRUS diseases

This result is not displayed to guests.
Login for full access.

An Open Label, Phase 2 Study to Assess the Efficacy and Safety of Tenalisib (RP6530), a PI3K δ/γ and SIK3 Inhibitor, in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)

Authors: Grosicki, Sebastian, Iosava, Genadi ^*, Zodelava, Mamia ^*, Tzvetkov, Nikolay ^*, Robak, Tadeusz, Radinoff, Atanas ^*, Routhu, Kasi Viswanath ^*, Barde, Prajak ^*, Nair, Ajit Mohanchandran ^*

Source: In Blood 5 November 2020 136 Supplement 1:25-25

This result is not displayed to guests.
Login for full access.

Daratumumab Plus Bortezomib, Melphalan, and Prednisone Versus Bortezomib, Melphalan, and Prednisone in Patients with Transplant-Ineligible Newly Diagnosed Multiple Myeloma: Overall Survival in Alcyone

Authors: Mateos, Maria-Victoria, Cavo, Michele ^*, Bladé, Joan, Dimopoulos, Meletios A., Suzuki, Kenshi, Jakubowiak, Andrzej, Knop, Stefan ^*, Doyen, Chantal, Lucio, Paulo ^*, Nagy, Zsolt ^*, Pour, Ludek ^*, Cook, Mark, Grosicki, Sebastian, Crepaldi, Andre H ^*, Liberati, Anna Marina, Campbell, Philip, Shelekhova, Tatiana ^*, Yoon, Sung-Soo, Iosava, Genadi ^*, Fujisaki, Tomoaki ^*, Garg, Mamta ^*, Krevvata, Maria ^*, Wang, Jianping ^*, Kudva, Anupa ^*, Ukropec, Jon, Wroblewski, Susan ^*, Kobos, Rachel, San-Miguel, Jesús

Source: In Blood 13 November 2019 134 Supplement 1:859-859

Phase 2/3 Trial of Subcutaneously Administered Marzeptacog Alfa (activated) an Engineered FVIIa in Hemophilia with Inhibitors - Pharmacokinetics, Pharmacodynamics, Safety and Efficacy

Authors: Levy, Howard ^*, Makhaldiani, Levani ^*, Iosava, Genadi ^*, Mahlangu, Johnny, Kosinova, Marina V ^*, Khacchatryan, Heghine ^*, Del Greco, Frank ^*, Booth, Frank V. McL. ^*

Source: In Blood 29 November 2018 132 Supplement 1:1198-1198

Rviii-Singlechain Pharmacokinetics and Safety in Children Less Than 12 Years of Age

Authors: Djambas Khayat, Claudia ^*, Stasyshyn, Oleksandra ^*, Iosava, Genadi ^*, Ong, Jeannie B ^*, Abdul Karim, Faraizah ^*, Bensen-Kennedy, Debra M., St. Ledger, Katie ^*, Limsakun, Tharin ^*, Veldman, Alex ^*, Pabinger, Ingrid

Source: In Blood 3 December 2015 126(23):3524-3524

This result is not displayed to guests.
Login for full access.

Efficacy and safety of the neonatal Fc receptor inhibitor efgartigimod in adults with primary immune thrombocytopenia (ADVANCE IV): a multicentre, randomised, placebo-controlled, phase 3 trial

Authors: Broome, Catherine M, McDonald, Vickie, Miyakawa, Yoshitaka, Carpenedo, Monica, Kuter, David J, Al-Samkari, Hanny, Bussel, James B, Godar, Marie, Ayguasanosa, Jaume, De Beuf, Kristof, Rodeghiero, Francesco, Michel, Marc, Newland, Adrian, Fillitz, Michael, Knoebl, Paul, Meers, Stef, Amine, Ismail Mohamad, Gumulec, Jaromir, Hlusi, Antonin, Mayer, Jiri, Quittet, Philippe, Viallard, Jean-Francois, Betaneli, Magdana, Datikashvili-David, Irine, Iosava, Genadi, Makhaldiani, Levan, Rejto, Laszlo, Sharashenidze, Nino, Groepper, Stefanie, Röth, Alexander, Hamed, Aryan, Illes, Arpad, Carpenedo, Monica, Artoni, Andrea, Bocchia, Monica, Gamberi, Barbara, Borchiellini, Alessandra, Oliva, Esther Natalie, Patriarca, Andrea, Tomassetti, Simona, Miyakawa, Yoshitaka, Ando, Kiyoshi, Handa, Hiroshi, Katsutani, Shinya, Nishiwaki, Kaichi, Ito, Shoko, Ito, Tomoki, de Boer, Fransien, Jansen, A.J. Gerard, Ciepluch, Hanna, Fornagiel, Szymon, Grosicki, Sebastian, Soroka-Wojtaszko, Maria, Trelinski, Jacek, Bakirov, Bulat, Borisenkova, Elena, Volodicheva, Elena, Shatokhin, Yuri, Proydakov, Andrey, Alonso, Maria Aranzazu, Mingot-Castellano, María Eva, Sanchez-Gonzalez, Blanca, Valcarcel Ferreiras, David, Ayli, Meltem, Hacibekiroglu, Tuba, Demir, Ahmet Muzaffer, Nalçaci, Meliha, Sonmez, Mehmet, Tombak, Anil, Toprak, Selami Kocak, Turgut, Burhan, Vural, Filiz, Yagci, Munci, Altuntas, Fevzi, Turgut, Mehmet, Kaya, Emin, Romanyuk, Nataliya, McDonald, Vickie, Kazmi, Syed Rashid Saeed, Broome, Catherine, Cataland, Spero, Doshi, Ketan, Lentz, Steven R., Boxer, Michael, Rosenberg, Richard

Source: The Lancet; 20230101, Issue: Preprints

A Phase 3 Study Evaluating the Efficacy and Safety of Lenalidomide (Len) Combined with Melphalan and Prednisone Followed by Continuous Lenalidomide Maintenance (MPR-R) in Patients (Pts) ≥ 65 Years (Yrs) with Newly Diagnosed Multiple Myeloma (NDMM): Updated Results for Pts Aged 65–75 Yrs Enrolled in MM-015

Authors: Palumbo, Antonio, Adam, Zdenek ^*, Kropff, Martin, Foà, Robin, Catalano, John, Gisslinger, Heinz, Wiktor-Jedrzejczak, Wieslaw ^*, Delforge, Michel, Weisel, Katja ^*, Cascavilla, Nicola ^*, Van Droogenbroeck, Jan ^*, Iosava, Genadi ^*, Cavo, Michele ^*, Blade, Joan, Beksac, Meral, Spicka, Ivan ^*, Plesner, Torben, Yu, Zhinuan ^*, Herbein, Lindsey ^*, Mei, Jay, Jacques, Christian J., Dimopoulos, Meletios Athanasios

Source: In Blood 18 November 2011 118(21):475-475

Forodesine (FodosineTM), a PNP Inhibitor Active in Relapsed or Refractory T-Cell Leukemia Patients (Phase II Study).

Authors: Furman, Richard R., Iosava, Genadi ^*, Isola, Luis, Ravandi, Farhad ^*, Zodelava, Mamia ^*, Bennett, J. Claude ^*, Kilpatrick, J. Michael ^*, Bantia, Shanta ^{*, *}

Source: In Blood 16 November 2005 106(11):881-881

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.