Novel drug transporter substrates identification: An innovative approach based on metabolomic profiling, in silico ligand screening and biological validation

Authors: Nies, Anne T., König, Jörg, Leuthold, Patrick, Damme, Katja, Winter, Stefan, Haag, Mathias, Masuda, Satohiro, Kruck, Stephan, Daniel, Hannelore, Spanier, Britta, Fromm, Martin F., Bedke, Jens, Inui, Ken-ichi, Schwab, Matthias, Schaeffeler, Elke

Source: In Pharmacological Research October 2023 196

Inhibitory effects of vandetanib on creatinine transport via renal organic cation transporter OCT2

Authors: Tanihara, Yuko, Masuda, Satohiro, Inui, Ken-ichi

Source: In European Journal of Pharmaceutical Sciences 1 March 2021 158

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters

Authors: Alexander, Stephen P H, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Southan, Christopher, Davies, Jamie A, Amarosi, Laura, Anderson, Catriona M. H., Beart, Philip Mark, Broer, Stefan, Dawson, Paul A., Hagenbuch, Bruno, Hammond, James R., Hancox, Jules C, Inui, Ken‐ichi, Kanai, Yoshikatsu, Kemp, Stephan, Stewart, Gavin, Thwaites, David T., Verri, Tiziano

Source: British journal of pharmacology. 178:S412-S513

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140911764.0x000001&indx=1&recIds=ETOCvdc_100140911764.0x000001

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Transporters

Authors: Alexander, Stephen P H, Kelly, Eamonn, Mathie, Alistair, Peters, John A, Veale, Emma L, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A, Anderson, Catriona MH, Bröer, Stefan, Dawson, Paul, Hagenbuch, Bruno, Hammond, James R, Hancox, Jules, Inui, Ken‐ichi, Kanai, Yoshikatsu, Kemp, Stephan, Thwaites, David T, Verri, Tiziano

Source: British journal of pharmacology. 176:S397-S493

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100093528364.0x000001&indx=1&recIds=ETOCvdc_100093528364.0x000001

Isolation and Characterization of a Digoxin Transporter and Its Rat Homologue Expressed in the Kidney

Authors: Mikkaichi, Tsuyoshi, Suzuki, Takehiro, Onogawa, Tohru, Tanemoto, Masayuki, Mizutamari, Hiroya, Okada, Masahiro, Chaki, Tatsuji, Masuda, Satohiro, Tokui, Taro, Eto, Nobuaki, Abe, Michiaki, Satoh, Fumitoshi, Unno, Michiaki, Hishinuma, Takanori, Inui, Ken-ichi, Ito, Sadayoshi, Goto, Junichi, Abe, Takaaki, Nakanishi, Shigetada

Source: Proceedings of the National Academy of Sciences of the United States of America, 2004 Mar 01. 101(10), 3569-3574.

Access URL: https://www.jstor.org/stable/3371520

Management of dose variability and side effects for individualized cancer pharmacotherapy with tyrosine kinase inhibitors

Authors: Terada, Tomohiro, Noda, Satoshi, Inui, Ken-ichi

Source: In Pharmacology and Therapeutics August 2015 152:125-134

Evaluation of the Potency of Telaprevir and Its Metabolites as Inhibitors of Renal Organic Cation Transporters, a Potential Mechanism for the Elevation of Serum Creatinine

Authors: Nakada, Tomohisa, Kito, Tomoko, Inoue, Katsuhisa, Masuda, Satohiro, Inui, Ken-ichi, Matsubara, Kazuo, Moriyama, Yoshinori, Hisanaga, Noriko, Adachi, Yasuhisa, Suzuki, Masayuki, Yamada, Ichimaro, Kusuhara, Hiroyuki ^*

Source: In Drug Metabolism and Pharmacokinetics 2014 29(3):266-271

Association between CYP3A5 Genotypes in Graft Liver and Increase in Tacrolimus Biotransformation from Steroid Treatment in Living-donor Liver Transplant Patients

Authors: Hosohata, Keiko, Uesugi, Miwa, Hashi, Sachiyo, Hosokawa, Mio, Inui, Ken-ichi, Matsubara, Kazuo, Ogawa, Kohei, Fujimoto, Yasuhiro, Kaido, Toshimi, Uemoto, Shinji, Masuda, Satohiro ^*

Source: In Drug Metabolism and Pharmacokinetics 2014 29(1):83-89

Precise comparison of protein localization among OCT, OAT, and MATE in human kidney

Authors: Motohashi, Hideyuki, Nakao, Yumi, Masuda, Satohiro, Katsura, Toshiya, Kamba, Tomomi, Ogawa, Osamu, Inui, Ken-Ichi ^*

Source: In Journal of Pharmaceutical Sciences September 2013 102(9):3302-3308

Multidrug and toxin extrusion family SLC47: Physiological, pharmacokinetic and toxicokinetic importance of MATE1 and MATE2-K

Authors: Motohashi, Hideyuki, Inui, Ken-ichi

Source: In Molecular Aspects of Medicine April-June 2013 34(2-3):661-668

Novel riboflavin transporter family RFVT/SLC52: Identification, nomenclature, functional characterization and genetic diseases of RFVT/SLC52

Authors: Yonezawa, Atsushi, Inui, Ken-ichi

Source: In Molecular Aspects of Medicine April-June 2013 34(2-3):693-701

Urinary chemokine (C-C motif) ligand 2 (monocyte chemotactic protein-1) as a tubular injury marker for early detection of cisplatin-induced nephrotoxicity

Authors: Nishihara, Kumiko, Masuda, Satohiro, Shinke, Haruka, Ozawa, Aiko, Ichimura, Takaharu, Yonezawa, Atsushi, Nakagawa, Shunsaku, Inui, Ken-ichi, Bonventre, Joseph V., Matsubara, Kazuo

Source: In Biochemical Pharmacology 15 February 2013 85(4):570-582

Involvement of autophagy in the pharmacological effects of the mTOR inhibitor everolimus in acute kidney injury

Authors: Nakagawa, Shunsaku, Nishihara, Kumiko, Inui, Ken-ichi, Masuda, Satohiro

Source: In European Journal of Pharmacology 5 December 2012 696(1-3):143-154

Impact of Genetic Variation in Breast Cancer Resistance Protein (BCRP/ABCG2) on Sunitinib Pharmacokinetics

Authors: Mizuno, Tomoyuki, Fukudo, Masahide, Terada, Tomohiro, Kamba, Tomomi, Nakamura, Eijiro, Ogawa, Osamu, Inui, Ken-ichi, Katsura, Toshiya ^*

Source: In Drug Metabolism and Pharmacokinetics 2012 27(6):631-639

Renal Tubular Secretion of Varenicline by Multidrug and Toxin Extrusion (MATE) Transporters

Authors: Kajiwara, Moto, Masuda, Satohiro ^*, Watanabe, Shingo, Terada, Tomohiro, Katsura, Toshiya, Inui, Ken-ichi

Source: In Drug Metabolism and Pharmacokinetics 2012 27(6):563-569

Plasma and Pleural Fluid Pharmacokinetics of Erlotinib and its Active Metabolite OSI-420 in Patients With Non–Small-Cell Lung Cancer With Pleural Effusion

Authors: Masago, Katsuhiro, Togashi, Yosuke, Fukudo, Masahide, Terada, Tomohiro, Irisa, Kaoru, Sakamori, Yuichi, Kim, Young Hak, Mio, Tadashi, Inui, Ken-ichi, Mishima, Michiaki

Source: In Clinical Lung Cancer September 2011 12(5):307-312

The Effect of ABCG2 Genotype on the Population Pharmacokinetics of Sunitinib in Patients With Renal Cell Carcinoma

Authors: Mizuno, Tomoyuki, Fukudo, Masahide, Fukuda, Tsuyoshi, Terada, Tomohiro, Dong, Min, Kamba, Tomomi, Yamasaki, Toshinari, Ogawa, Osamu, Katsura, Toshiya, Inui, Ken-ichi, Vinks, Alexander A., Matsubara, Kazuo

Source: Therapeutic drug monitoring. 36(3):310-316

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100030254640.0x000001&indx=1&recIds=ETOCvdc_100030254640.0x000001

Reduced Renal Clearance of a Zwitterionic Substrate Cephalexin in Mate1-Deficient Mice

Authors: Watanabe, Shingo, Tsuda, Masahiro, Terada, Tomohiro, Katsura, Toshiya, Inui, Ken-ichi ^*

Source: In The Journal of Pharmacology and Experimental Therapeutics August 2010 334(2):651-656

Cerebrospinal Fluid Concentration of Erlotinib and its Active Metabolite OSI-420 in Patients with Central Nervous System Metastases of Non-small Cell Lung Cancer

Authors: Togashi, Yosuke, Masago, Katsuhiro, Fukudo, Masahide, Terada, Tomohiro, Fujita, Shiro, Irisa, Kaoru, Sakamori, Yuichi, Kim, Young Hak, Mio, Tadashi, Inui, Ken-ichi, Mishima, Michiaki

Source: In Journal of Thoracic Oncology July 2010 5(7):950-955

Identification and Comparative Functional Characterization of a New Human Riboflavin Transporter hRFT3 Expressed in the Brain1–3

Authors: Yao, Yoshiaki, Yonezawa, Atsushi, Yoshimatsu, Hiroki, Masuda, Satohiro, Katsura, Toshiya, Inui, Ken-ichi ^*

Source: In The Journal of Nutrition July 2010 140(7):1220-1226