En la búsqueda de la nefroprotección. Los pilares del tratamiento 2024.

Alternate Title: In the pursuit of nephroprotection. The pillars of the 2024 treatment.

Authors: Inserra, Felipe¹ felipe.inserra@gmail.com

Source: Revista de Nefrología Diálisis y Trasplante. 2024, Vol. 44 Issue 4, p211-222. 12p.

Subject Terms: *TYPE 2 diabetes, *MINERALOCORTICOID receptors, *CHRONIC kidney failure, *RENIN-angiotensin system, *KIDNEY diseases

¿Por qué debemos bloquear el SRA en prácticamente todas las condiciones de ERC?

Alternate Title: Why should we block the SRA in practically all CKD conditions?

Authors: Inserra, Felipe¹ felipe.inserra@gmail.com

Source: Revista de Nefrología Diálisis y Trasplante. 2024, Vol. 44 Issue 4, p169-171. 3p.

Subject Terms: *CHRONIC kidney failure, *RENIN-angiotensin system, *PROTEINURIA, *DISEASE progression, *PHYSICIANS

Protección cardiovascular, renal y cerebral, de los iSGLT2. Mecanismos hemodinámicos, tisulares y celulares implicados.

Alternate Title: Cardiovascular, renal, and cerebral protection by SGLT2. Hemodynamic, tissular, and cellular mechanisms involved.

Authors: Inserra, Felipe¹ felipe.inserra@gmail.com, Lavenia, Gustavo¹, Taylor, Marcelo Fabian¹, Castellaro, Carlos¹

Source: Revista de Nefrología Diálisis y Trasplante. jul-sep2023, Vol. 43 Issue 3, p184-196. 13p.

Subject Terms: *GLYCEMIC control, *MEDICAL research, *CARDIOVASCULAR disease prevention, *PEOPLE with diabetes, *CELL anatomy, *KIDNEY disease prevention, *DIABETES, *OXIDATIVE stress, *KIDNEY diseases, *METABOLIC disorders

Mitochondrial-epigenetic crosstalk as an integrative standpoint into gut microbiome dysbiosis and related diseases.

Authors: SIMãO, VINíCIUS AUGUSTO, CHUFFA, LUIZ GUSTAVO DE ALMEIDA, FERDER, LEóN, INSERRA, FELIPE, MANUCHA, WALTER

Source: Biocell; 2024, Vol. 48 Issue 10, p1429-1442, 14p

Subject Terms: SHORT-chain fatty acids, ORGANIC conductors, GENE expression, MITOCHONDRIAL pathology, HISTONE deacetylase, PROBIOTICS, GUT microbiome

Vitamin D high doses supplementation could represent a promising alternative to prevent or treat COVID-19 infection

Alternate Title: El suplemento con altas dosis de vitamina D podría representar una alternativa promisoria para prevenir o tratar la infección por COVID-19 (Spanish; Castilian)

Authors: Mansur, José Luis, Tajer, Carlos, Mariani, Javier, Inserra, Felipe, Ferder, León, Manucha, Walter ^*

Source: In Clínica e Investigación en arteriosclerosis (English edition) November-December 2020 32(6):267-277

El suplemento con altas dosis de vitamina D podría representar una alternativa promisoria para prevenir o tratar la infección por COVID-19

Alternate Title: Vitamin D high doses supplementation could represent a promising alternative to prevent or treat COVID-19 infection (English)

Authors: Mansur, José Luis, Tajer, Carlos, Mariani, Javier, Inserra, Felipe, Ferder, León, Manucha, Walter

Source: In Clinica e Investigacion en Arteriosclerosis November-December 2020 32(6):267-277

Lungs as target of COVID-19 infection: Protective common molecular mechanisms of vitamin D and melatonin as a new potential synergistic treatment

Authors: Martín Giménez, Virna Margarita, Inserra, Felipe, Tajer, Carlos D., Mariani, Javier, Ferder, León, Reiter, Russel J., Manucha, Walter

Source: In Life Sciences 1 August 2020 254

Nuevas ecuaciones basadas en creatinina y cistatina C para la TFGe, sin incluir raza.

Alternate Title: New equations based on creatinine and cystatin C for eGFR, not including race.

Authors: Inserra, Felipe^1,2,3 felipe.inserra@gmail.com, Greloni, Gustavo^1,4,5,6

Source: Revista de Nefrología Diálisis y Trasplante. abr-jun2022, Vol. 42 Issue 2, p99-102. 4p.

Subject Terms: *SOCIAL impact, *RACE, *CYSTATIN C, *GLOMERULAR filtration rate, *BLACK people

Geographic Terms: UNITED States

Renin–angiotensin system inhibitors positively impact on multiple aging regulatory pathways: Could they be used to protect against human aging?

Authors: de Cavanagh, Elena M. V.¹ (AUTHOR) elenacavanagh@yahoo.com.ar, Inserra, Felipe^2,3 (AUTHOR), Ferder, León² (AUTHOR)

Source: Physiological Reports. Jun2024, Vol. 12 Issue 12, p1-31. 31p.

Subject Terms: *ACE inhibitors, *RENIN-angiotensin system, *ANGIOTENSIN-receptor blockers, *AGING, *PRESSURE regulators, *MORPHOGENESIS, *AMP-activated protein kinases

Evaluación de la función renal para la detección y seguimiento de la Enfermedad Renal Crónica. Documento Multidisciplinario de Consenso 2021. Especial atención sobre situaciones clínicas específicas (Resumen ejecutivo).

Alternate Title: Assessment of renal function for the detection and monitoring of Chronic Kidney Disease. Multidisciplinary Consensus Document 2021. Special attention to specific clinical situations (Executive summary).

Authors: Inserra, Felipe¹ felipe.inserra@gmail.com, Lía Torres, María², Alles, Alberto¹, Bonelli, Carlos W.^1,3, Ceci, Romina², Corradino, Claudio^1,3, Echegoyen, Cecilia², Fraga, Adriana¹, Gilabert, Tomás¹, Girardi, Raúl², Greloni, Gustavo¹, Lujan, Pablo², Luxardo, Rosario¹, Pennacchiotti, Graciela L.⁴, Villagra, Alberto⁵

Source: Revista de Nefrología Diálisis y Trasplante. 2021, Vol. 41 Issue 4, p300-303. 4p.

High-dose vitamin D versus placebo to prevent complications in COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial (CARED-TRIAL)

Authors: Mariani, Javier, Tajer, Carlos, Antonietti, Laura, Inserra, Felipe, Ferder, León, Manucha, Walter

Source: Trials. 22(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194018667.0x000001&indx=1&recIds=ETOCvdc_100194018667.0x000001

Vitamin D supplementation: An alternative to enhance the effectiveness of vaccines against SARS-CoV-2?

Authors: Inserra, Felipe, Tajer, Carlos, Antonietti, Laura, Mariani, Javier, Ferder, León, Manucha, Walter

Source: Vaccine. 39(35):4930-4931

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100134164599.0x000001&indx=1&recIds=ETOCvdc_100134164599.0x000001

Metabolic Syndrome and Cardiac Remodeling Due to Mitochondrial Oxidative Stress Involving Gliflozins and Sirtuins.

Authors: Sanz, Raúl Lelio, Inserra, Felipe, García Menéndez, Sebastián, Mazzei, Luciana, Ferder, León, Manucha, Walter

Source: Current Hypertension Reports; Jun2023, Vol. 25 Issue 6, p91-106, 16p

2022 World Hypertension League, Resolve To Save Lives and International Society of Hypertension dietary sodium (salt) global call to action

Authors: Campbell, Norm R. C., Whelton, Paul K., Orias, Marcelo, Wainford, Richard D., Cappuccio, Francesco P., Ide, Nicole, Neal, Bruce, Cohn, Jennifer, Cobb, Laura K., Webster, Jacqui, Trieu, Kathy, He, Feng J., McLean, Rachael M., Blanco-Metzler, Adriana, Woodward, Mark, Khan, Nadia, Kokubo, Yoshihiro, Nederveen, Leo, Arcand, JoAnne, MacGregor, Graham A., Owolabi, Mayowa O., Lisheng, Liu, Parati, Gianfranco, Lackland, Daniel T., Charchar, Fadi J., Williams, Bryan, Tomaszewski, Maciej, Romero, Cesar A., Champagne, Beatriz, L’Abbe, Mary R., Weber, Michael A., Schlaich, Markus P., Fogo, Agnes, Feigin, Valery L., Akinyemi, Rufus, Inserra, Felipe, Menon, Bindu, Simas, Marcia, Neves, Mario Fritsch, Hristova, Krassimira, Pullen, Carolyn, Pandeya, Sanjay, Ge, Junbo, Jalil, Jorge E., Wang, Ji-Guang, Wideimsky, Jiri, Kreutz, Reinhold, Wenzel, Ulrich, Stowasser, Michael, Arango, Manuel, Protogerou, Athanasios, Gkaliagkousi, Eugenia, Fuchs, Flávio Danni, Patil, Mansi, Chan, Andy Wai-Kwong, Nemcsik, János, Tsuyuki, Ross T., Narasingan, Sanjeevi Nathamuni, Sarrafzadegan, Nizal, Ramos, María Eugenia, Yeo, Natalie, Rakugi, Hiromi, Ramirez, Agustin J., Álvarez, Guillermo, Berbari, Adel, Kim, Cho-il, Ihm, Sang-Hyun, Chia, Yook-Chin, Unurjargal, Tsolmon, Park, Hye Kyung, Wahab, Kolawole, McGuire, Helen, Dashdorj, Naranjargal J., Ishaq, Mohammed, Ona, Deborah Ignacia D., Mercado-Asis, Leilani B., Prejbisz, Aleksander, Leenaerts, Marianne, Simão, Carla, Pinto, Fernando, Almustafa, Bader Ali, Spaak, Jonas, Farsky, Stefan, Lovic, Dragan, Zhang, Xin-Hua

Source: Journal of Human Hypertension; June 2023, Vol. 37 Issue: 6 p428-437, 10p

Zinc deficiency during growth: Influence on renal function and morphology

Authors: Tomat, Analía Lorena, Costa, María Angeles, Girgulsky, Luciana Carolina, Veiras, Luciana, Weisstaub, Adriana Ruth, Inserra, Felipe, Balaszczuk, Ana María, Arranz, Cristina Teresa

Source: In Life Sciences 2007 80(14):1292-1302

EFECTOS RENALES DE LOS AGONISTAS GLP-1 EN LA DIABETES TIPO 2. (Spanish)

Alternate Title: Renal effects of GLP-1 agonists in type 2 diabetes. (English)

Authors: ELBERT, ALICIA, CASTELLARO, CARLOS, LITWAK, LEON, INSERRA, FELIPE, WASSERMANN, ALFREDO, SINAY, ISAAC

Source: Medicina (Buenos Aires); jul/ago2022, Vol. 82 Issue 4, p576-590, 15p, 8 Diagrams, 3 Charts, 1 Graph

Angiotensin II, mitochondria, cytoskeletal, and extracellular matrix connections: an integrating viewpoint.

Authors: De Cavanagh, Elena MV, Ferder, Marcelo, Inserra, Felipe

Source: American Journal of Physiology; March 2009 pt2, Vol. 296 Issue 3, pH550-H558, 9p

Moderate zinc restriction during fetal and postnatal growth of rats: effects on adult arterial blood pressure and kidney.

Authors: Tomat, Analía Lorena, Inserra, Felipe, Veiras, Luciana

Source: American Journal of Physiology; August 2008 pt2, Vol. 295 Issue 2, pR543-R549, 7p

Protective effect of the inhibition of the renin–angiotensin system on aging

Authors: Basso, Nidia ^*, Paglia, Nora, Stella, Inés, de Cavanagh, Elena M.V., Ferder, León, del Rosario Lores Arnaiz, María, Inserra, Felipe

Source: In Regulatory Peptides 2005 128(3):247-252

High-dose vitamin D versus placebo to prevent complications in COVID-19 patients: Multicentre randomized controlled clinical trial.

Authors: Mariani, Javier, Antonietti, Laura, Tajer, Carlos, Ferder, León, Inserra, Felipe, Sanchez Cunto, Milagro, Brosio, Diego, Ross, Fernando, Zylberman, Marcelo, López, Daniel Emilio, Luna Hisano, Cecilia, Maristany Batisda, Sebastián, Pace, Gabriela, Salvatore, Adrián, Hogrefe, Jimena Fernanda, Turela, Marcela, Gaido, Andrés, Rodera, Beatriz, Banega, Elizabeth, Iglesias, María Eugenia

Source: PLoS ONE; 5/27/2022, Vol. 17 Issue 5, p1-16, 16p

Subject Terms: VITAMIN D, CLINICAL trials, COVID-19, LENGTH of stay in hospitals, HOSPITAL mortality, DISEASE risk factors, DIETARY supplements

Geographic Terms: ARGENTINA